Computational Chemistry 1.2 - PDB File Format

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  • Опубликовано: 21 дек 2024

Комментарии • 20

  • @randomwords102
    @randomwords102 7 лет назад +4

    This is freaking amazing. Thank you so much!

    • @TMPChem
      @TMPChem  7 лет назад +5

      I appreciate this very non-random selection of words.

  • @weekendresearcher
    @weekendresearcher 4 года назад +5

    Thanks a ton! Got a pdb of a proposed inhibitor for 2019-nCoV..can study the files better now.

  • @rtgo
    @rtgo 3 года назад +2

    Very useful video for starters with the PDB format. Small note: it is B-factor, not Beta-factor.

    • @TMPChem
      @TMPChem  3 года назад +3

      I looked around quite a bit after your comment to see if there is any source which refers to it as "beta" rather than "b", and I can't seem to find any. Perhaps it is a fabrication of my imagination. I assume the choice of "b" starting with the same letter as the thermodynamic property "beta", or inverse temperature times Boltzmann constant is a non-coincidence, though I'm surprised to see it not referred to as such in any references. Strange.

  • @mrhisenberg1763
    @mrhisenberg1763 3 года назад

    How can I change the charge of a metal ion like Zn in a pdb file to perform docking?

  • @Gokrix
    @Gokrix 7 лет назад +2

    Thanks I was searching for this, do you think you can also do a tutorial on using bioPython for PDB?

    • @TMPChem
      @TMPChem  7 лет назад +4

      Hi Gokul. I'm not an expert in many of the tools that are commonly used among macromolecular / atomistic biomodeling researchers. My experience is primarily in gas phase small molecule simulations where structure generation is not a prohibitively complicated problem as it is for proteins / nucleotides / etc. in the absence of good crystal structures. I'm happy to comment where my experience has given me the ability to, but it is wise for individuals to stay in their lane in public while discussing highly specialized topics in the role of an expert / authority figure.

    • @devargyachakraborty9068
      @devargyachakraborty9068 5 лет назад

      @@TMPChem do you have any tutorial of ionic liquid simulation uswing LAAMS

  • @joachimjohansen5796
    @joachimjohansen5796 7 лет назад

    Thank you so much!

    • @TMPChem
      @TMPChem  7 лет назад +1

      Thanks for watching, Joachim.

  • @sabrango
    @sabrango 4 года назад

    thx!

  • @andreyvartanyan6964
    @andreyvartanyan6964 4 года назад

    Thanks u

  • @vicenterubio6218
    @vicenterubio6218 3 года назад

    Drink some water before recording. Avoid the cotton mouth.

    • @TMPChem
      @TMPChem  3 года назад +1

      Sadly it's pretty much unavoidable. I drink a lot of fluids in daily life and am still clearing my throat all the time.

  • @marianaql
    @marianaql 6 лет назад

    Well done! Thx

    • @TMPChem
      @TMPChem  6 лет назад

      Thanks, Mariana!

  • @nithya2003
    @nithya2003 Год назад

    Thank you so much!!