Aaron’s spirit is AMAZING! “If it can’t help me, hopefully they can learn enough from me that it can help the next person..”. What a generous human being!❤
If they are able to restore sight i hope this man knows that every single human being from now to the end of time, who regains their sight via transplant, owes it in part, to him. Man is written into history. The doctors, researchers, and patient are actively laying the groundwork for humans to conquer blindness. What an amazing time to be alive. Think about how many countless people could have their sight restored again because of what started here. Human kind is sometimes awe inspiring. I hope him and the doctors keep making history
@@loganq I was talking about realistically thinking about the development of the tech itself. It's extremely difficult developing tech just to pick up signals from nerves to send to prosthetics, how do you plan on making an entire sensory organ that can connect to the optic nerve to send information? On the other hand we have transplants from dead people, which is more realistic since we've been doing it for a while now and its easier to work with since you're essentially just attaching something that you're sure is functional and letting the body deal with the rest by healing. TLDR: How are you so sure robotic eyes will be what you envision when we are nowhere close to that level of technology?
If you ignore the entire financial angle of that kind of surgery, then sure. But realistically most blind people currently alive would never be able to have that operation.
Will someone be able to afford it? Will a doctor have enough experience to do it? Will there be enough tax money to cure the whole blind population? Just questions of mine, you don't have to answer
@@Davian2073 as a taxpayer's ROI ending SS-payment's from one transplant at about 20yo patient is worthwhile but after 80yo probably not as most won't live past 82 or so anyways and complications from doing it might ended them in the hospital so other treatments are more effective im like this blind-man's attitude of he knows it's experimental but if it helps others and becomes routine ect, its a good thing, medical advancement would not happen without risk taker's and unfortunately war-criminals like DR.-deaths camp-experiment's, id rather have volunteers for advancing than forcing against someone's will
@@tackytrooper In the U.S. that would be the case, unless they adopt a system that doesn't put such a financial burden on those who rely on it. Countries that already have a single payer system wouldn't have this problem.
@monroe496 For sure. Im not completely blind in both eyes. But I may as well only have 1 since my left eye only works if my right eye is closed. So even if this surgery were capable of restoring vision. I don't know that it would work for me because of the dominant eye thing.
As a guy with regular sight problems, myopia and colorblindness this gives me hope too. With so many advancements, maybe in 10 years we'll get eye transplants and in 20 we'll get colorblindness treatment with stem cell injections
This is amazing! My 1 year old was born without eyes (but luckily has her optic nerves). If she could even get 1 eye transplant it would change her life. I wonder if it would even be easier because the nerves from her eye to optic nerve to her brain would not need to be re-written, it would just be like a baby opening it’s eyes for the first time.
Unfortunately it's the other way around - the longer the nerves and visual cortex go without stimulation, especially early in life in the critical periods when development is meant to occur, the more permanent the damage is. E.g. even if someone is simply born with treatable cataracts, the surgery must be done ASAP otherwise even when it's done the eyesight will always be extremely limited. In cases when someone can't get the cataracts removed as a baby because they don't have access to medical care, if it's done when they're an older child they still end up only partially sighted even once the cataracts are completely cured, because it's too late for the optic nerve and visual cortex to fully develop. The ideal time for the surgery is pretty much a newborn.
@@junbh2my friend has a degenerative eye condition and was getting confusing images from both eyes when she was little. Doctors covered one and let her brain forget about that eye. She's blind in one eye (but better vision overall). Modern medicine meant a surgery became available quite recently. Surgeons fixed both eyes. She's still only got vision in one eye (much better vision, actually). Like you've suggested, there's more to seeing than having healthy eyes - the brain plays the bigger part.
If a new born never had eye's then the brain won't develop the neuronal pathways needed to be able to interpret visual signals coming from a new pair of eyes... At least not easily. Maybe that will change one day.
The eye transplant is amazing. But also can I just say that the face transplant is definitely the best one that has ever been done so far? What a fantastic result all around. ❤
I can only but dream for the day we can repair optic nerve damage, I have optic disc atrophy, it’s taken away my driving licence and my perfect vision. Hopefully scientists and doctors will achieve this in my lifetime.
I understand where you are coming from, I have ocular albinism and I’ve never had a drivers license, I used to dream of driving and being independent, I’m 63 now and maybe a cure will be found in my lifetime.
After watching this, it brought me to attention to look at my experience as a bit of light to my city. I was first diagnosed with a Hemangioma on my tongue at 3, and after 3 'failed' surgeries, was upgraded to a Vascular Malformation. By the age of 10, and the only child in my city to have it, I've had 12 surgeries and one of them consisted of the removal of my tongue just behind the tonsils, to the front tip, and reattach it upside-down. We didn't have the greatest equipment at the children's hospital in the 90's. It wasn't until I was 15 and on my 3rd surgeon, he bought a used YAG laser from the US with his own money to further test treatments on me. 19 was my last surgery (over 25 surgeries total) and by this point, has been in remission for almost 20 years. I do get the odd flare-up. Also, from MRI results, it's not just my tongue, but my entire left side of jaw and down into trachea.
This is amazing. Even though the eye doesn't send visual information to his brain, it's still fantastic that the transplanted eye is doing as well as it is. Maybe someday people with my eye condition (retinopathy of prematurity) will have surgical options available to us. I'm praying for Aaron, and any/all the doctors who have worked, or who will work with him. What an exciting time to be alive.
@@robinvanderpal372 Responding for him but he is right. Praying is quite pointless for anything at all really. And if some does pray, the issue with that is they most likely believe in some fictional, higher up force. I mean, I know religion is influential but like... The bible is literally just the biggest piece of fiction literature ever and nothing beyond that. So are all of the holy books.
This is a milestone! Once scientists figure out how to get optical nerves to bind together again and function, eye transplants could become mainstream. i wonder if they are getting closer, however, because there are reports of full arm transplants that have worked and nerves were joining to the point where the person can move the arm and fingers. Fingers crossed!
As someone who’s had both eyes removed as a child but still have most of my optic nerve this is so encouraging to me. This is a great step towards helping so many people.
Gives us hope and other direction. As I had surgery due to glaucoma and spent a month in bed being blind hoping to recover my eye pressure... I decided to end my life when blind again due to glaucoma... Now, I know that I don't have to (maybe)...
Wow. Thanks for the video, Michael! I had a nearly 20 year career in eyecare starting out working as a lab tech making prescription lenses, then 15+ years as an ophthalmic tech. Spent the last 3 years of that working for retina specialists. Got burned out and needed to take a break for a while, but that "while" has been almost 8 years so far. I often wonder how much has advanced in ophthalmology since 2015, all I've learned is "still there" like muscle memory, and sometimes I feel like I could just pick up where I left off, but I'm positive there's a lot of new methods and tech I'm unaware of. If anything, it's nice to see a video like this as it may be the catalyst of returning.
Really cool of him to accept the risks with the hope of teaching and helping others in the future. Human experimentation is incredibly useful but it MUST be done with informed consent and this is a great example of that.
To this point where he had the guts to put the first ever eye in another person those doctors need to put EVERYTHING on the table to get his vision. This is history. And it's actually really cool just because milestones are being hit. My late aunt had cancer twice, if she didn't go for the clinical trials, well, it would've been over like 10 years ago. Or even 2 years ago. She died because of something else and i'm kinda happy to say that. You can recognize a warrior by it's scars.
The face transplant looks like it went really well. He looks good! Congrats to Aaron & his amazing doctors for such a milestone. It'll be amazing if he manages to regain sight in the new eye. That would so cool.
I applaud the Doctors, gives ppl hope for future . They didn’t expect eyesight to return , but watch the work they have done , and the eye transplant was necessary , and it helps the future patients .
The coolest and best thing would be if in the future they can make artificial bionic eyes and artificial optical nerves and have it transplanted and the artificial nerve going all the way back into the brain where the sight is interpreted. To somehow simulate the same way a real optical nerve would transmit the electrical signals. If that would ever happen it would set the stage for tremendous things in sight.
I can tell you from my own experience with two detached retinas…. Tissues like retina cells that are not supposed to be able to regenerate….they do! It’s been a lot of years, but the eye they said I’d never regain useful sight in again, it’s 1000% better than after the operation. The human body somehow knows what to do I think. On things that are as critical for survival as eyesight, I think the body figures out its own solution and I bet that’s what’s happening for that blessed guy in his optic nerve.
Amazing times we live in....thank you for this wonderful and informative video. Perhaps one day they may even be able to transplant a brain for those that lack one.
The nerve connections would be too complex to ever accomplish vision restoration via an eye transplant. To answer your question, vision would have to be restored using a prosthetic eye camera connected to stimulate the olfactory lobe sensor area similar to Neuralink but as a receiver not a sender.
The very first heart transplant patient only lived 18 days before passing away. Today the average life expectancy for a heart transplant patient is about 10 years although some have lived on for more than 20 years with one person living for more than 30 years. Why does this matter? It matters because once someone took the first step, even if it wasn't an immediate success, it opened the flood gates and the technology and knowledge in that field improved to the point where today, heart transplants are an almost common procedure and can extend a person's life with at least 10 years. Imagine what the field of eye transplants will be like in 50 years. Perhaps it will also be a more common procedure and even though we can't yet regenerate nerves, in 50 years we might be able to do that and even more. But you have to start somewhere, no matter how pointless it might seem.
His statement to his partner post accident and her response made my eyes leaky. "Look, if you want to leave, you know, I get it." - "No we're in this until the end"
so... my mother suffered with lupus, an autoimmune disease, she died in 2006 and was an organ donor. Due to the lupus they couldn't really use her organs but they could use her eyes because of "eye immune privilege" and I was told that two people received eye sight because of her. Was that not an eye transplant then???
I wonder if injecting Yamanaka factors where the optic nerve is attached could restore vision. Somehow even if that works, I suspect it would be garbled and just distracting, as nerve alignment is probably far from correct, and he would have to keep the eyelid closed most of the time.
So many blessings to the family of the donors family. So name blessings and so much gratitude to this man and his family for not giving up and willingness to help all of humanity in receiving this transplant. Praises to the teams who have worked so hard to further our understanding of science so humanity will benefit.
You can reattach an arm to a person and it will still work. What is the difference to that is attaching an eye to the optic nerve which causes it to not work? Is the optic nerve too complicated for current medical understanding to successfully make an operation like this? How long until this should be possible?
@@Katchi_ I didn't make any broad claims though? I was asking why vision doesn't return if you connect the optic nerve in an operation when transplanting an eye. Unless you mean the claim that an arm can be reattached and still work, which have been something doctors can do since the 60s...
Actually there have only been 300 attempts at hand transplants (not the same as reattaching a person's own hand which was cut off in an accident) and only about 100 of those people have reported recovering ANY sensation. So it's not an easy thing to even do that, and the signals from a hand are far less complicated than the signals from an eye. Your hand doesn't have to tell you what frequency the light waves are hitting it to interpret into colors for instance.
And actually even reattachment of the hand only really relies on blood flow and working tendons to be able to close the hand, they don't even have to worry about if you can feel your fingers, just if you can close them.
@@kristyw89 where did you find the source for the number 300? I looked but couldn't find any numbers. And I think I said "still work", didn't talk about sensations, but limb replantation success rate is over 80% though. For hands I found a source saying 100 had been done so far, but they have over 90% success and feeling can return even after several years, so I suppose it's all about time for nerves to reconnect. I suppose that's something that could happen to the eye transplant if we wait a few years? I still don't think my statement that we can reattach an arm and it will still work is incorrect 🤷♂️
Damn, I’m impressed! That is so much science wrapped up in one operation! 140 surgeons, nurses, and healthcare professionals. On one operation? Damn, that was some technical stuff. I just don’t know what to say.
Using an Optomap on the retina is incredible because they’re also capable of viewing and tracking the macular health and longevity of the transplanted eye.
I’m very impressed at how your videos are so easy to understand and super informative. All I want for next Christmas is an iPhone camera to replaced one of my eyes.
My girlfriend fell down a few years ago and she has nerve damage in her leg as a result. From what I hear, the nerve was pretty much flattened, and she has lost the ability to lift her right foot. I’m really hoping this paves the way for better and more affordable stem cell procedures, so she can eventually restore feeling and movement in her foot and no longer be a fall risk. As parents, it’s been really hard on both of us. Part of me is hoping that there’s enough nerve there that it could provide a scaffolding for stem cells, another part hopes new nerve tissue can be grafted onto it. But we are neither wealthy nor in a great place for such a procedure. Fortunately technology is moving faster than it ever has, so hopefully solutions are around the corner.
First time I see one of his videos, he's a really good speaker. He got me exited thinking about the investigation to be done and the further undersanding of how our body can be fixed. Regards.
Hopefully this man can soon see out of that eye. He’s definitely pioneering something really special and potentially opening the door for other blind people to regain their vision through these new types of surgeries.
A January 29th, 2014 I went into a Cancer center in is Bakersfield California to have a carcinoma removed from my nose. Unfortunately it was much more advanced than I thought that only was my nose taken but part of my cheek area and it was all the way down to the bone., Unfortunately this left a huge gaping hole in my face. Thanks to the kindness of a grieving family I received a partial face transplant with his nose and I have had it on my face for the last ten years. I thank him and his family every day from this gift and all of you should think about putting that little pink dot on your driver's license it could help a lot of people live a better life.
If someone is a doctor can you tell me, can we mix the donor body's dna using crispr with the receiver to avoid rejection? Essencially disquising the receivers body as the donor's
Hopefully first for his sake he surprises the world & gains exceptional eyesight. More importantly our heroes the donor & his family for making this possible. Yes lets pray the risk taken to perform this surgery pays off in treatments & cures in 2024 & beyond.
If he gained slight light perception and his eye reacted to a flashlight in the eye, that would already be near miraculous and would make medical history. The doctors don't expect that to happen though.
If I remember correctly nerves can heal but it's like on a basis of years not like months or a year so since it's an extremely sensitive area this could take 10 plus years for his optic nerves to attach to his new nerve endings in the new eyeball
I'm 39yo. I've been 90% blind in one eye due to an injury when I was 3. I've had countless surgeries including artificial lens implant, just to save the eye. I love seeing this technology move forward. I can't imagine what it would be like to be able to see out of eyes.
Thanks for your videos. I still have many to view. Some questions that I have not heard answers by you or other eye doctors. 1 - For monofocal iol implant, how close should the patient see 20-20 for far vision (8th ? line on an eye chart pinned to a wall). 2 - Do monofocal iol come in different sizes and how is the size determined? 3 - What are the difference in monofocal iol? Can the differences be measured in numerical percentages of (a) light passing through and (b) contrast sensitivity? 4 - Compare the eyhance and iPure. 5 - What is seen through a multi-focal iol? I tried a tri-focal eyeglasses and found that I had to bob my head up and down among the 3 lenses to find the usable one. A nuisance and a pain in the neck. Thanks in advance for your answers.
Wouldn't the optic nerve dry out and die where it was cut off from the eyeball, during the time he was waiting for a donor? What did the surgeons do to keep that from happening?
Nothing. They state clearly that this has no chance of restoring his vision. Even if the optic nerve is perfectly undamaged we have no ability to connect it. It's kind of just medical research. 'Success' in this case means the eye has blood flow and hasn't gotten diseased or died or something. But it doesn't do anything.
I thought this was a fake video - based on my education, nerve can't be attached, hopefully they learn something and can get better at it. This is a great step.
Interesting! Since Aaron naturally has light blue eyes, I wonder if his brown donor eye will stay brown or eventually lose some of it's melanin and turn the same colour as the other eye.
I am glad it looks like it worked out for him and didn't get rejected or anything. I don't know if I was in his situation if I could have gone through with it. It is nice of him to risk it all to help research.
You know if you think about it Apple and the human body are kind of the same, both serialize their parts and don't accept third party parts. I think the EU should really make a law and fix this.
The key to vision is the optical nerves and retina to recieve light signals. If they can find a way to regenerate the patients own retina cells and transplant it to an artificial eyeball which is superior in its function and structure to human eyeball then there is no need for a live organ transplant. Like prosthetic arms and legs, an artificial eye can be attached to the ciliary muscles of the eye socket to enable the patient to move his eye and adjust the focus.
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Aaron’s spirit is AMAZING! “If it can’t help me, hopefully they can learn enough from me that it can help the next person..”. What a generous human being!❤
I thought the same thing. What a beautifull human being!
@ianchandley @ghaloise are you both aliens, I'm getting a vibe you two are aliens.
@@cosmicwavexd28You are the one called cosmicwave ;)
@@cosmicwavexd28 aliens? SOUNDS LIKE WE GOTTA DELIVER SOME FREEDOM AND DEMOCRACY TO THEM RAAAAHHHHH
@@NahIdSword no, dont tickle a lion feet in his sleep. Or we will armageddoned 😂
This guy is a pioneer to eye transplants. I hope we learn so much from this and hope he lives long to share the tale. Amazing time to be alive
FOOL.
FYI This surgery was done at NYU Langone and I believe the ophthalmologist involved was Vaidehi S. Dedania, MD,
Thanks internet guy
when you lost your eyes then you understand that they was better than all gems in the world.
If they are able to restore sight i hope this man knows that every single human being from now to the end of time, who regains their sight via transplant, owes it in part, to him. Man is written into history. The doctors, researchers, and patient are actively laying the groundwork for humans to conquer blindness. What an amazing time to be alive. Think about how many countless people could have their sight restored again because of what started here. Human kind is sometimes awe inspiring.
I hope him and the doctors keep making history
It's much more likely they'll use robotic eyes.
@@loganqand what makes you think that?
@@lambertmariano1680Because the robotic eyes will be more available, standardized and able to interface with technology.
@@loganq I was talking about realistically thinking about the development of the tech itself.
It's extremely difficult developing tech just to pick up signals from nerves to send to prosthetics, how do you plan on making an entire sensory organ that can connect to the optic nerve to send information?
On the other hand we have transplants from dead people, which is more realistic since we've been doing it for a while now and its easier to work with since you're essentially just attaching something that you're sure is functional and letting the body deal with the rest by healing.
TLDR: How are you so sure robotic eyes will be what you envision when we are nowhere close to that level of technology?
@lambertmariano1680 Elon Musk already has answered a lot of these questions.
if they figure out how to get his eye working, that means blindness has been cured from damaged eyes
It’s extremely unlikely he will ever seen from that eye.
If you ignore the entire financial angle of that kind of surgery, then sure. But realistically most blind people currently alive would never be able to have that operation.
Will someone be able to afford it? Will a doctor have enough experience to do it? Will there be enough tax money to cure the whole blind population? Just questions of mine, you don't have to answer
@@Davian2073 as a taxpayer's ROI ending SS-payment's from one transplant at about 20yo patient is worthwhile but after 80yo probably not as most won't live past 82 or so anyways and complications from doing it might ended them in the hospital so other treatments are more effective
im like this blind-man's attitude of he knows it's experimental but if it helps others and becomes routine ect, its a good thing, medical advancement would not happen without risk taker's and unfortunately war-criminals like DR.-deaths camp-experiment's, id rather have volunteers for advancing than forcing against someone's will
@@tackytrooper In the U.S. that would be the case, unless they adopt a system that doesn't put such a financial burden on those who rely on it. Countries that already have a single payer system wouldn't have this problem.
As a dude born blind in an eye this fills me with so much hope.
Same here!!!
@monroe496 For sure. Im not completely blind in both eyes. But I may as well only have 1 since my left eye only works if my right eye is closed. So even if this surgery were capable of restoring vision. I don't know that it would work for me because of the dominant eye thing.
I was too but,it’s all the way through to the optic nerve so this leap wouldn’t help me but WHAT A LEAP in medicine!!!
I was born with both but managed to damage both at one point and then get a nail stuck in one some years later which is totally blind now.
As a guy with regular sight problems, myopia and colorblindness this gives me hope too. With so many advancements, maybe in 10 years we'll get eye transplants and in 20 we'll get colorblindness treatment with stem cell injections
He has the best possible outlook and attitude.
Best of luck to him.
This is amazing! My 1 year old was born without eyes (but luckily has her optic nerves). If she could even get 1 eye transplant it would change her life. I wonder if it would even be easier because the nerves from her eye to optic nerve to her brain would not need to be re-written, it would just be like a baby opening it’s eyes for the first time.
Let's hope in the future 🙏
The nerve would not work in this case, unfortunately
Unfortunately it's the other way around - the longer the nerves and visual cortex go without stimulation, especially early in life in the critical periods when development is meant to occur, the more permanent the damage is. E.g. even if someone is simply born with treatable cataracts, the surgery must be done ASAP otherwise even when it's done the eyesight will always be extremely limited. In cases when someone can't get the cataracts removed as a baby because they don't have access to medical care, if it's done when they're an older child they still end up only partially sighted even once the cataracts are completely cured, because it's too late for the optic nerve and visual cortex to fully develop. The ideal time for the surgery is pretty much a newborn.
@@junbh2my friend has a degenerative eye condition and was getting confusing images from both eyes when she was little. Doctors covered one and let her brain forget about that eye. She's blind in one eye (but better vision overall).
Modern medicine meant a surgery became available quite recently. Surgeons fixed both eyes. She's still only got vision in one eye (much better vision, actually). Like you've suggested, there's more to seeing than having healthy eyes - the brain plays the bigger part.
If a new born never had eye's then the brain won't develop the neuronal pathways needed to be able to interpret visual signals coming from a new pair of eyes... At least not easily. Maybe that will change one day.
The eye transplant is amazing. But also can I just say that the face transplant is definitely the best one that has ever been done so far? What a fantastic result all around. ❤
This is incredible! Even if he never gains sight, it's a huge step forward to understanding what is possible in the future.
Aaron has a heroic spirit. I hope miracles happen for him.
I can only but dream for the day we can repair optic nerve damage, I have optic disc atrophy, it’s taken away my driving licence and my perfect vision. Hopefully scientists and doctors will achieve this in my lifetime.
I understand where you are coming from, I have ocular albinism and I’ve never had a drivers license, I used to dream of driving and being independent, I’m 63 now and maybe a cure will be found in my lifetime.
This guy just paved the way forward to help so many folks with missing eyes now that we know it works.
Gullibleloser.
This made me so conscious of the pains people go through. Bless this man. I hope he recovers quickly.
After watching this, it brought me to attention to look at my experience as a bit of light to my city. I was first diagnosed with a Hemangioma on my tongue at 3, and after 3 'failed' surgeries, was upgraded to a Vascular Malformation. By the age of 10, and the only child in my city to have it, I've had 12 surgeries and one of them consisted of the removal of my tongue just behind the tonsils, to the front tip, and reattach it upside-down. We didn't have the greatest equipment at the children's hospital in the 90's. It wasn't until I was 15 and on my 3rd surgeon, he bought a used YAG laser from the US with his own money to further test treatments on me. 19 was my last surgery (over 25 surgeries total) and by this point, has been in remission for almost 20 years. I do get the odd flare-up. Also, from MRI results, it's not just my tongue, but my entire left side of jaw and down into trachea.
He got hurt at his old job, but never quit looking for the next one. A real hero.
This is amazing. Even though the eye doesn't send visual information to his brain, it's still fantastic that the transplanted eye is doing as well as it is.
Maybe someday people with my eye condition (retinopathy of prematurity) will have surgical options available to us.
I'm praying for Aaron, and any/all the doctors who have worked, or who will work with him.
What an exciting time to be alive.
Praying doesn't work. There's no Skylord.
@@joevarga5982Good God!
@@joevarga5982 Is that a nice thing to say to a well-meaning person, Joe?
@@robinvanderpal372 Get lost, troll. I'm not the one who brought up religion on here.
@@robinvanderpal372 Responding for him but he is right. Praying is quite pointless for anything at all really. And if some does pray, the issue with that is they most likely believe in some fictional, higher up force. I mean, I know religion is influential but like... The bible is literally just the biggest piece of fiction literature ever and nothing beyond that. So are all of the holy books.
This is a milestone!
Once scientists figure out how to get optical nerves to bind together again and function, eye transplants could become mainstream.
i wonder if they are getting closer, however, because there are reports of full arm transplants that have worked and nerves were joining to the point where the person can move the arm and fingers.
Fingers crossed!
Society goes so far and evolve so fast yet there are still people who belive in this rainbow nonsense.
Getting a pair of Kiroshis.
@@Azetaris Gay people exist. Get over it.
@@Azetaris it isn’t harming anyone so why do you care?
@@Azetarissociety has evolved a lot but some people are still bigots. Hint. You.
We shouldn't be asking whether he can see, rather how powerful his genjutsu!
As someone who’s had both eyes removed as a child but still have most of my optic nerve this is so encouraging to me. This is a great step towards helping so many people.
I hope we get you either a transplant or cybernetic eyes soon.
Wait a minute, if you have no eyes, how did you type this comment? 🤔
@@ghoulbuster1 my phone talks. Technology is amazing.
@@ghoulbuster1wow how ignorant haha
@@Gaffermanhey there's no bad questions. This one question that seems ignorant to you might have been enlightening to one hundred people.
You were a good story teller. Made the science entertaining. Not to mention the uplifting spirit of Aaron.
This is juicy! We are living in the dark ages of medical care, but the future is bright.
b r i g h t
What a dumb fucking comment.
We lived in the dark ages of medicine until about the mid 1850s where science started to catch on.
As someone with Uveitis, who is always scared of pressure causing glaucoma and eventual vision loss. This is a surprisingly hopeful story.
Gives us hope and other direction. As I had surgery due to glaucoma and spent a month in bed being blind hoping to recover my eye pressure... I decided to end my life when blind again due to glaucoma... Now, I know that I don't have to (maybe)...
I'll save u ten minutes. He can't see.
Dang
Thx man
Admire Aaron's spirit and sacrifice!
They also did a partial face transplant and it looks really good
Thx bro
Damn imagine how cool it will be when we get the 1st eye transplant where patient will see, can't wait :)
This is awesome! I respect Aaron going through with the surgery if nothing else, to provide beneficial information to the medical field as a whole.
I’m starting med school this September and stories like this are so amazing and fascinating and I just can’t WAIT to join the field!
Wow. Thanks for the video, Michael! I had a nearly 20 year career in eyecare starting out working as a lab tech making prescription lenses, then 15+ years as an ophthalmic tech. Spent the last 3 years of that working for retina specialists. Got burned out and needed to take a break for a while, but that "while" has been almost 8 years so far.
I often wonder how much has advanced in ophthalmology since 2015, all I've learned is "still there" like muscle memory, and sometimes I feel like I could just pick up where I left off, but I'm positive there's a lot of new methods and tech I'm unaware of. If anything, it's nice to see a video like this as it may be the catalyst of returning.
I really hope him the best
Eye & partial face loss can happen to anybody at any time. Audience wishes him all the best. Cheers!
Well, thanks for making my anxiety go 📈📈📈💀
This sounds as goundbreaking as hearing about the first ever internal organ transplant. Exciting stuff for the world of medicine.
Really cool of him to accept the risks with the hope of teaching and helping others in the future.
Human experimentation is incredibly useful but it MUST be done with informed consent and this is a great example of that.
Outstanding. Determination is key. I read about the first heart transplant. It was pushing the limits, thats how we go further!
I love how you smiled while talking about this, shows youre passionate about this and health science in general. Kudos to you.
7:48 OMG this shows what he looked like before. No wonder he couldn’t eat solid food.
Scary as hell🫣. Reminds me the Nemesis boss from Resident evil.😬
To this point where he had the guts to put the first ever eye in another person those doctors need to put EVERYTHING on the table to get his vision. This is history. And it's actually really cool just because milestones are being hit. My late aunt had cancer twice, if she didn't go for the clinical trials, well, it would've been over like 10 years ago. Or even 2 years ago. She died because of something else and i'm kinda happy to say that. You can recognize a warrior by it's scars.
The face transplant looks like it went really well. He looks good! Congrats to Aaron & his amazing doctors for such a milestone. It'll be amazing if he manages to regain sight in the new eye. That would so cool.
Short version: He can't see.
Just Be Quiet .
What Do You Know ??? SMDH.
@@dukeofrideshare I watched a video. Try it some time, TROLL.
@@joevarga5982 So Did I . Just SHTFU !
@@joevarga5982 Put your self in Arron's place, I pray for him to be able to see again.
@@uNknownrMx Praying doesn't work. There's no God.
I’m glad to see doctors didn’t turn a blind eye to it.
Absolutely amazing!!And the fortitude of Aaron and his family are out of this world. Good luck to all xx
Amazing! One stop closer to unlocking the Eternal Mangekyo!
I applaud the Doctors, gives ppl hope for future . They didn’t expect eyesight to return , but watch the work they have done , and the eye transplant was necessary , and it helps the future patients .
The coolest and best thing would be if in the future they can make artificial bionic eyes and artificial optical nerves and have it transplanted and the artificial nerve going all the way back into the brain where the sight is interpreted. To somehow simulate the same way a real optical nerve would transmit the electrical signals. If that would ever happen it would set the stage for tremendous things in sight.
maybe they need to go at this backwards, try to create a mechanical eye with camera that can interpret the brain signals from the optic nerve
It's heartbreaking to see he suffered such a terrible injury. It's also a miracle he survived. I wish him all the best in his recovery.
I can tell you from my own experience with two detached retinas…. Tissues like retina cells that are not supposed to be able to regenerate….they do! It’s been a lot of years, but the eye they said I’d never regain useful sight in again, it’s 1000% better than after the operation. The human body somehow knows what to do I think. On things that are as critical for survival as eyesight, I think the body figures out its own solution and I bet that’s what’s happening for that blessed guy in his optic nerve.
What an honor it would be to take part in such an exciting experiment! I can't wait to see how it progresses.
Amazing times we live in....thank you for this wonderful and informative video. Perhaps one day they may even be able to transplant a brain for those that lack one.
This is a very good man, Thank you Aaron , we all love you and wish you the best in life.
I hope this surgery would be named after him.
The nerve connections would be too complex to ever accomplish vision restoration via an eye transplant. To answer your question, vision would have to be restored using a prosthetic eye camera connected to stimulate the olfactory lobe sensor area similar to Neuralink but as a receiver not a sender.
This is the side of human beings and human interaction that gives me hope for our futures
I subscribed to your channel for more such information .
Hope you will be bigger youtuber one day who will influence PPL for good
Wow! To have a chance at future vision is a great thing!
This is incredible
The very first heart transplant patient only lived 18 days before passing away. Today the average life expectancy for a heart transplant patient is about 10 years although some have lived on for more than 20 years with one person living for more than 30 years. Why does this matter? It matters because once someone took the first step, even if it wasn't an immediate success, it opened the flood gates and the technology and knowledge in that field improved to the point where today, heart transplants are an almost common procedure and can extend a person's life with at least 10 years. Imagine what the field of eye transplants will be like in 50 years. Perhaps it will also be a more common procedure and even though we can't yet regenerate nerves, in 50 years we might be able to do that and even more. But you have to start somewhere, no matter how pointless it might seem.
His statement to his partner post accident and her response made my eyes leaky. "Look, if you want to leave, you know, I get it." - "No we're in this until the end"
so... my mother suffered with lupus, an autoimmune disease, she died in 2006 and was an organ donor. Due to the lupus they couldn't really use her organs but they could use her eyes because of "eye immune privilege" and I was told that two people received eye sight because of her. Was that not an eye transplant then???
I wonder if injecting Yamanaka factors where the optic nerve is attached could restore vision. Somehow even if that works, I suspect it would be garbled and just distracting, as nerve alignment is probably far from correct, and he would have to keep the eyelid closed most of the time.
I am a left leg amputee and blind on the left eye,im hoping 1 day that eye transplant would just a ordinary proceedure and not a very rare one
Acclimating to his new face! DAMN! It's not just the eye but also a FACE TRANSPLANT? DAMN!
If not him, I hope to soon see vision restoration surgeries in the near future.😊
No he can’t see through that eye! there I saved you 10 minutes
thank a lot
Thanks
So many blessings to the family of the donors family. So name blessings and so much gratitude to this man and his family for not giving up and willingness to help all of humanity in receiving this transplant. Praises to the teams who have worked so hard to further our understanding of science so humanity will benefit.
Remember that accident. I too work on powerlines. Hope all goes well brother we are praying for you!
RESPECT! for doing what your all doing
You can reattach an arm to a person and it will still work. What is the difference to that is attaching an eye to the optic nerve which causes it to not work? Is the optic nerve too complicated for current medical understanding to successfully make an operation like this? How long until this should be possible?
You making broad claims does not make it true....
@@Katchi_ I didn't make any broad claims though? I was asking why vision doesn't return if you connect the optic nerve in an operation when transplanting an eye. Unless you mean the claim that an arm can be reattached and still work, which have been something doctors can do since the 60s...
Actually there have only been 300 attempts at hand transplants (not the same as reattaching a person's own hand which was cut off in an accident) and only about 100 of those people have reported recovering ANY sensation. So it's not an easy thing to even do that, and the signals from a hand are far less complicated than the signals from an eye. Your hand doesn't have to tell you what frequency the light waves are hitting it to interpret into colors for instance.
And actually even reattachment of the hand only really relies on blood flow and working tendons to be able to close the hand, they don't even have to worry about if you can feel your fingers, just if you can close them.
@@kristyw89 where did you find the source for the number 300? I looked but couldn't find any numbers. And I think I said "still work", didn't talk about sensations, but limb replantation success rate is over 80% though. For hands I found a source saying 100 had been done so far, but they have over 90% success and feeling can return even after several years, so I suppose it's all about time for nerves to reconnect. I suppose that's something that could happen to the eye transplant if we wait a few years? I still don't think my statement that we can reattach an arm and it will still work is incorrect 🤷♂️
Hopefully he'll be able to regain vision one day.
Stuff like this is what makes me so interested in science and makes me excited about the possibilities we’ll have in the future.
Curious how much harder it is to not only transplant the eye but the vision also. I can only imagine it being many times harder.
Never though I would be following an eye doctor, but damn dude you are very well spoken
Damn, I’m impressed! That is so much science wrapped up in one operation! 140 surgeons, nurses, and healthcare professionals. On one operation? Damn, that was some technical stuff. I just don’t know what to say.
Using an Optomap on the retina is incredible because they’re also capable of viewing and tracking the macular health and longevity of the transplanted eye.
The first flight is from Santos-Dumont, not the Wright brothers.
Medical advancements and Science behind it is so fucking amazing.
Dude did it all for the better of the world!
I didn't know you could transplant a whole face like that... wild... I hope it all works out!
I hope everything goes well and more people can get benefits of that.
Aaron, all the best mate!
I’m very impressed at how your videos are so easy to understand and super informative. All I want for next Christmas is an iPhone camera to replaced one of my eyes.
if it can be connected to your brain. not sure how it will be wired. but i would be happy if i get back even 10% of my eye sight for the bad eye
My girlfriend fell down a few years ago and she has nerve damage in her leg as a result. From what I hear, the nerve was pretty much flattened, and she has lost the ability to lift her right foot. I’m really hoping this paves the way for better and more affordable stem cell procedures, so she can eventually restore feeling and movement in her foot and no longer be a fall risk. As parents, it’s been really hard on both of us. Part of me is hoping that there’s enough nerve there that it could provide a scaffolding for stem cells, another part hopes new nerve tissue can be grafted onto it. But we are neither wealthy nor in a great place for such a procedure. Fortunately technology is moving faster than it ever has, so hopefully solutions are around the corner.
Starts with girlfriend then changes to parents. You banging your daughter?
@@Katchi_reading comprehension. Him and his girlfriend are parents; they have children.
First time I see one of his videos, he's a really good speaker.
He got me exited thinking about the investigation to be done and the further undersanding of how our body can be fixed.
Regards.
Hopefully this man can soon see out of that eye. He’s definitely pioneering something really special and potentially opening the door for other blind people to regain their vision through these new types of surgeries.
A January 29th, 2014 I went into a Cancer center in is Bakersfield California to have a carcinoma removed from my nose. Unfortunately it was much more advanced than I thought that only was my nose taken but part of my cheek area and it was all the way down to the bone., Unfortunately this left a huge gaping hole in my face. Thanks to the kindness of a grieving family I received a partial face transplant with his nose and I have had it on my face for the last ten years. I thank him and his family every day from this gift and all of you should think about putting that little pink dot on your driver's license it could help a lot of people live a better life.
Wow! I love the way you explain everything. You got a new sub. Amazing video!
If someone is a doctor can you tell me, can we mix the donor body's dna using crispr with the receiver to avoid rejection?
Essencially disquising the receivers body as the donor's
Hopefully first for his sake he surprises the world & gains exceptional eyesight. More importantly our heroes the donor & his family for making this possible. Yes lets pray the risk taken to perform this surgery pays off in treatments & cures in 2024 & beyond.
If he gained slight light perception and his eye reacted to a flashlight in the eye, that would already be near miraculous and would make medical history. The doctors don't expect that to happen though.
If I remember correctly nerves can heal but it's like on a basis of years not like months or a year so since it's an extremely sensitive area this could take 10 plus years for his optic nerves to attach to his new nerve endings in the new eyeball
I'm 39yo. I've been 90% blind in one eye due to an injury when I was 3. I've had countless surgeries including artificial lens implant, just to save the eye. I love seeing this technology move forward. I can't imagine what it would be like to be able to see out of eyes.
They are so far away..
I'm 95% blind in both eyes, so no offense..we won't see that day
holy crap , i had a wisdom tooth removed n thought "I am incomplete :(" I couldnt survive what he is going through. very strong willed person man.
Thanks for your videos. I still have many to view. Some questions that I have not heard answers by you or other eye doctors. 1 - For monofocal iol implant, how close should the patient see 20-20 for far vision (8th ? line on an eye chart pinned to a wall). 2 - Do monofocal iol come in different sizes and how is the size determined? 3 - What are the difference in monofocal iol? Can the differences be measured in numerical percentages of (a) light passing through and (b) contrast sensitivity? 4 - Compare the eyhance and iPure. 5 - What is seen through a multi-focal iol? I tried a tri-focal eyeglasses and found that I had to bob my head up and down among the 3 lenses to find the usable one. A nuisance and a pain in the neck. Thanks in advance for your answers.
Madara did it in 2 seconds mid fight
Face transplant looks surprisingly good.
OSK Treatment would likely restore vision. It already has in mice and is currently in testing with NHP
Wouldn't the optic nerve dry out and die where it was cut off from the eyeball, during the time he was waiting for a donor? What did the surgeons do to keep that from happening?
Nothing. They state clearly that this has no chance of restoring his vision. Even if the optic nerve is perfectly undamaged we have no ability to connect it. It's kind of just medical research. 'Success' in this case means the eye has blood flow and hasn't gotten diseased or died or something. But it doesn't do anything.
@@junbh2 Will he be able to at least move the eye around, even if that eye doesn't actually see anything?
I wonder if he has to take any medication to keep his body from rejecting the foreign eyeball.
I thought this was a fake video - based on my education, nerve can't be attached, hopefully they learn something and can get better at it. This is a great step.
Interesting! Since Aaron naturally has light blue eyes, I wonder if his brown donor eye will stay brown or eventually lose some of it's melanin and turn the same colour as the other eye.
I am glad it looks like it worked out for him and didn't get rejected or anything. I don't know if I was in his situation if I could have gone through with it. It is nice of him to risk it all to help research.
But did he awaken the eternal mangekyo sharingan tho?
I wonder how long that eye will remain viable, and whether or not it causes him any pain/discomfort.
You know if you think about it Apple and the human body are kind of the same, both serialize their parts and don't accept third party parts. I think the EU should really make a law and fix this.
The key to vision is the optical nerves and retina to recieve light signals. If they can find a way to regenerate the patients own retina cells and transplant it to an artificial eyeball which is superior in its function and structure to human eyeball then there is no need for a live organ transplant. Like prosthetic arms and legs, an artificial eye can be attached to the ciliary muscles of the eye socket to enable the patient to move his eye and adjust the focus.