Turning supplements into serotonin, kinda…
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- Опубликовано: 7 сен 2024
- Warning: do not attempt the actions seen in this video!
In today's video, I'll be making a neurotransmitter called serotonin! This compound regulates many functions in the body from mood to bowel movements but is commonly called the happiness chemical! So follow me today as I turn over-the-counter supplements into serotonin!
Enjoy! :)
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Trying and failing to produce lots of serotonin - I'm sure many people watching can relate :)
Unfortunately yes. It doesn't help that I lost my SSRIs at a hotel...
@@peir5074 I lost my virginity in a hotel
@@xmuzel did you see a plastic bag with medication in it when you were doing it by any chance?
@@peir5074 huh you know this might explain why no sex has been as good since?
Came here to comment something along those lines but couldn't phrase it as good as you did! 10/10
As a chemist who is currently synthesizing tryptamine analogs, I can in fact agree 130% that these scaffolds are very difficult to make. There is a reason why any time a new indole/tryptamine synthesis comes out it is always highly regarded and is from a very notable publisher like Nature. Although, if you want a tryptamine that is a bit more active centrally from an OTC source, I suggest you research melatonin de-acetylation to 5-MeO-Tryptamine.
🧐
Melatonin is scheduled in south africa
@Hilton Elske how in the world is melatonin scheduled?
@Jeffrey Schultz ask SAHPRA although its not heavily enforced
Probably following the same system as some other countries. Any substance that can be prescribed by a doctor is automatically scheduled. The only unregulated substances are the once’s with no proven effects i.e. no pharmaceutical use.
You're trying much harder to feel joy than most depressed ppl. Respect.
^ ur calling me out and it's super true
Dumbass commet
As a most depressed people i agree.
@@alanwatts8239 get happy
And you’re tha judge for that?
Imagine trying to synthesize serotonin but ending up making cursed mochi as a byproduct
Lol 😂
😂
the forbidden mochi 😋😋
What is mochi
@@BlackBeavisThataIsntReallyBlac imagine chewy bubblegum but you can eat it
I had a 8th grade teacher that made us read a book called "the cure" she loved the part where they drank "serotonin shakes"
I'm pissing myself laughing now knowing they were just drinking diarrhea shakes
No!!! You're wasting the ingredient for the piss shakes!
Nah I think it mostly refers to the drug mdma
Tbh, when you had a long constipation and you sit on the Porcelain Throne and your bowels are shaking and you feel like Saturn V taking off...that releases some serotonin.
@@isekaiexpress9450
More like endorphins, hurts so good DADDY
Serotonin doesn't cross the blood-brain barrier, so the shits is all you would get to be fair.
Incidentally Serotonin is implicated in the venom of a number of different species owing to it's tendency to produce irritation in the form of itching, exploiting it's purpose in the sensory function of the skin in mammals among others.
You probably already heard it, but I imagine that if you hadn’t boiled the first solution you’d have been fine. Heating flours of any kind causes the starches that they’re made of to gelatinize.
Also, if you change the Hydroxyl group from the... 5 to the 3 position, its psilocin.
Psilocin is 4-HO-DMT. So he would have to move it to the 4-position and stick 2 methyl groups on the amine.
@@brandonbennett3082 Right, I couldn't remember off the top of my head. I feel like mushrooms are like more of an entourage effect rather than just psilocin.
@@granderondeproductions3286 i.e
Psilocybin
Psilocin
Aeruginascin
Baeocystin
and their metabolites.
You re-taught my body on how to make serotonin
Very nice man! It's neat coincidence that you made this, because I'm actually working on synthesizing another neurotransmitter on my channel: dopamine! Not sure when I'll finish though...anyways, keep up the good work; love the content!
Love the content man! Looking forward to that video and the anhydrous hydrazine video!
Hey, I'm working on figuring out a synthesis of dopamine too, tbh I find the litterature pretty scarce on non enzymatic pathways. I'm interested, what pathway where you thinking of doing?
Science madness has some procedures I think.
@@sashboo1370 have you tried meth?
What would you do if you had 98% pure piperine?
As a casual chemical enjoyer, i think its really cool that your also showing the steps that failed and also the reasonings why
I recently started taking melatonin at night and I've realized it boosted my serotonin greatly, i didnt even d oit on purpose. Im not super happy, but but I'm not sad like a i was and ive been getting lots of stuff done, 10 times what i was before.
A lot of hormones are responsible for therapy for depression besides Serotonin. Gaba regulators, NMDA receptor antagonists, Mu receptor inhibitors (like in some antidepressants and Opioids). Brain chemistry and stress hormones are essential but there is nothing that can increase or decrease Cortosone without massive side-effects or death. Yes, i find an antidepressant agent that are newer for Resistant depression is very cool. Nice video.
next video should be making Benzo's for the yo gaba gaba receptors.
Kappa Opioid Receptor*
@@williamwinn948 and ending up in jail lol
@sigma male depends on which benzo. Not all are scheduled or illegal to possess
@TheTaintPainter KOR receptors are responsible for stress and dysphoria.
The MOR and DOR receptors are responsible for base hedonic tone, ie mood and pleasure and are extremely important
You’re very fun to watch and listen to tbh. It’s like my friend telling and showing me something cool.
Or like the diary of a mad scientist
bro described being para-social
@@eltigre5785 you’ll one day learn that it’s okay to give a genuine compliment, show gratitude and leave it at that. Y’all quick to be bitter and weird about everything these days.
I’m glad that you included some caveats because the serotonin hypothesis of depression has been fairly comprehensively junked.
as a person who's had depression, and thought a chemical was my way out, well i never found one that wasnt temporary.. But what did work for me was: starting to exercise daily, cutting out alcohol & processed foods / sugars. its like putting crappy fuel in your car and expecting it to run well.
What do you eat on day to day basis? I have worked my way almost out of depression but I'm still really lazy and have a lot of pain issues that I wanna fix. I have been trying to at least walk everyday but I've had hard time getting back to lifting weights
B b but I need my kfC double downs
I love decarbing! I convert THCa regularly! Great video
Same here, my favorite substance to decarb yet!
Pothead humor is lost on me after moving back to the south.
@@shieeeet2334 Oh, good for you! Now go fly your stars 'n bars, OK?, OK!!
HAHAHAHAH i was searching for this typa comment right after boy said DECARBING
RUclips algorithm wild. This has no relevance to my life whatsoever, but I enjoyed it all
As an accomplished home cook that specializes in Japanese food, I was screaming "NO" when you added the water to that rice flour.
The only thing you're making with that are noodles, mochi, or some delicious tempura.
"Dot are yoi toin? Haayyyyiiaaa..."
L
Young man anytime you see rice flour, to add water with heating will always result in gravy. Lesson learned. We are happy to see new content, you will go far. wishing you luck for the future.😊
Not sure how pertinent to this video this will be but here it goes, I was on the edge of ending it and I told a friend and he said, "Hey man before you do something so brash why not try drugs first?" I was like ummm what kind of friend are you? but he told me 'You got NOTHING to lose in your opinion right?' So I said,......"Well yeah", Anyway we went downtown and bought some Crystal Methh. He showed me how to smoke it and I am not kidding you it saved my life that day.
Wanna talk about joy you should never feel? HOLY SH*T I felt so happy and said I would never think of such things again. I got a bit of a habit for awhile but I am not kidding you when I say Drugs saved my life. I am cureenty clean and I am still pro drug in certain situations because it can save your life if you are very depressed......I wouldn't suggest it to ANYONE unless you are getting close to the edge.
I have never seen anything else with such unclear instructions and I love it..
This is why I ove mushrooms (as a functional food). They both stimulate serotonin activity (like ye’ olde LSD) but support serotonin synthesis because of the tryptophan content. It also works upon the PNS (remember 5ht is also a hormone - and we do have 5ht2a receptors outside the brain) not *just* the CNS.
Genuine question here: given that psychedelics compete for serotonin in the receptors are we really getting extra serotonin? Psychedelics push serotinin out of the way to fit in the receptor.
@@TwiggySquidz causing an increase in free floating seratonin. Or the "afterglow" effect of psychedelics.
@@HerbaMachina Interesting, do you know of any good articles about this that I could read?
5:08 i've been doing chemistry amateurly for years and not once did i think of this, genius!
Great video man! If you're looking at neurotransmitters the endocannabinoid system some and there's a natural fatty acid that interacts with that system. I'm going to butcher the spelling but it's n-arachidoyldopamine. It would be fairly straightforward if you can get the fatty acid then maybe get it to an aldehyde and react it with dopamine to form an imine and reduce it. Great video man indole compounds are really cool!
Pleasure, joy, anticipation for pleasure and happiness are 4 completely different feelings and States of mind
dmt and ghb are my favorite neurotransmitters to make :)
Ghb is a dissociative what kind of weirdo are you. Dmt is fine
I mean you could just eat psilocybin mushrooms to fight depression... Just saying... You could make a tincture from the mushrooms so you can use drops for micro dosing. It's truly effective at eliminating depression.
Myco-life bro 🤘🤘
Another gem recommend by youtube. So happy to find you. All the best to you
Appreciate it!
Me: *Casually opens RUclips*
The first video suggested:
Me: *Reads comments*
Fedboi: *Leans in*
Awesome video. You did a good job at keeping attention even though it's 20 minutes.
Came here to say I actually love your style of production way more than NileRed. I really resonate with that dirty kitchen homemade chem lab vibe.
The most amazing thing I've seen all week... next to homemade graphene but that was impossible to be. The double gravity filtration unit!
I'm a Master technician & machinist & stumbled across your video. I'm amazed at your intelligence & your youthful age. I know nothing about chemistry & feel even less intelligent about the subject lol! But I'm glad we have people like you with awesome knowledge. Thanks for your time & hard work. I did learn a few things.
A much better solvent choice for initial extraction would be an alcohol or acetone if you have a bunch of starch or cellulose.❤
It's amazing that the body can make this naturally
it doesnt/ you need to consume tryptamine rich foods to converted to 5htp then serotonin
@@originsdecoded3508so it's made in the body then.
@@scotsman9755 so your body literally makes it. Idk why that distinction had to be mad3 that’s literally your body making serotonin, which is what op said.
@bretthepler722 you joined RUclips on the 28th of July 2013. 💩
I think anandamide should be your next target. It is a fatty acid amide that is the endogenous cannabinoid that activates CB1 and CB2 receptors. You could start with EPA eicosapentanoic (omega-3 /fish oil) acid to get to arachidonic acid then from there substitute in the amide group for the COOH.
What an earth have I found. Deep rabbit hole tonight. Younger me when I was more interested in this would’ve been amazing
On the topic of depression, SSRIs are overprescibed and kinda outdated/ineffective as seen in recent meta analyses. You could absolutely annihilate depression with a combination of tak-653(Ampa pam), Neboglamine(nmda pam), Pinealon (endogenous serotonin production), and agmatine sulphate. Which are all now readily available
Would you say that youre not depressed?
Sure bud 🙄
I don't know who you are or why RUclips recommended this video to me, but I'm glad it did.
I take a ton of psychedelics and this got me into this stuff, and I was gonna say that the serotonin was gonna just go into the gut once you mentioned digesting it, but then you mentioned it! It also looks very similar to 4-Aco-DMT (O-Acetylpsilocin).
Synthetic shrooms
it kind of looks like hash, i could imagine it being smokeable since its melting point is 120°
Lmao people who have taken psychs know the effects of serotonin on the gut lol
@@gigiman8324 youd destroy it and probably get crappy hits with anything but a glass nectar collector
It's also almost exactly the same as psilocin
I love how you failed many times, but showed it and continued anyways. Subbed for being real.
I'm 1:45 into this video and I already know not to snort pure serotonin 👍. This video is great
He never mentioned snorting serotonin, he was talking about taking serotonin orally/eating/swallowing it. Judging by your comprehension skills though, no, you shouldn't be ingesting pure serotonin in any shape or form regardless of the dosage or method of ingestion.
@@chaoticatmos1461 The Audacity you have to mention comprehension skills and then completely and utterly fail to comprehend my point.
Why do humans snort things? Because it goes straight past the blood brain barrier. He said serotonin cannot pass through the blood beain barrier. Therefore if you want the effects of Serotonin, snorting it is not the play.
He doesn't need to mention snorting when I have a brain and I fucking think for myself you actual brain dead mannequin
@Blingy McDaddy "didn't hear him not mention it" What? & Why are we making drugs? To practice chemistry thru actual experience in person. If you think that the end product on many of these videos is just for ingestion, than you are significantly misinformed, & you are exactly the kind of person who should stay away from the videos.
@Blingy McDaddy it can to take a lot strength to self reflect, thank you for taking the time to look at yourself.
@Blingy McDaddy leave chemistry to professionals or people who actually want to learn, if you want to be consuming drugs go to your local plug/substance dealer.
That was very funny the " I don`t know what it is. " and even the boiling point of water is different from website to website. In fact the whole thing had a tone like, " This is still better quality info than libraries found online offer. ".
That has been my experience of it as well.
You gained a sub this is definitely a new favorite channel I hope to learn with you !
This channel fills the NileRed shaped hole in my heart
Most antidepressants converge at their ability to induce BDNF expression, the serotonin system is but one of the ways to acheive this affect, even this depends on which receptors are involved.
Yeah, I get rapid long term activity from 7,8-dihydroxyflavone, AMPAkanes like Sunifiram, and NSI-189!
just think you made the world a happier place.
Psilocin (from psilocybin mushrooms) is a great agonist of serotonin receptors to abuse as a psychedelic or in low dosages as an antidepressant or nootropic. I'm not sure if supplemental serotonin would be able to cross the blood-brain barrier to cause a psychological effect.
Good old 4-HO-DMT
Joy is much more complicated than just serotonin!! God I wish it was that simple!
Great! So I can make a potent AND cursed laxative? Hell yeah!
3:33 also, why didn't you thought it was going to become cooked rice?
5:55 The forbidden coffee.
Thought that maybe I’d still be able to filter it lol
@@PyrotechnicalScience Lol. At least you now know how to make rice paste. Next time try using it to make a cursed bread lol
Ingest enough SAMe (S-Adenosyl methionine) and you will most likely have your intestines produce enough serotonin to get the same effect.
This makes so much sense how when on psilocybin or dmt you feel a Rush of happiness
Acetophenone has the best results, but separation is usually a bitch, because of the tryptamine-acetophenone imine being very stable for some reason. Better results are obtained by decarboxylation in turpentine containing a few % DMSO, using d-carvone as the ketone catalyst. Also for salt formation you want want to look into making the benzoate or fumarate salts. As benzoic acid or fumaric acid is soluble in organic solvents. Gassing tryptamines with HCl gas is not the way to go, usually results in tarry mess.
btw if you have brown amine salts, try cleaning them up by boiling with activated carbon.
Not really sure what i see in this video, apart from an Amateur Chemist actually Doing stuff to see if it works !
Awesome.
The Experience simply cannot be gained any other way - definitely not by reading.
Bravo !
You remind me of a younger version of myself playing around with chems in the back yard with improvised equipment sometimes making different substances for fun and intrigue.
People refer to getting serotonin from watching a funny video online when really they should say dopamine because that’s the neurotransmitter associated with short term happiness.
New to your channel and enjoyed science at school but never did anything with it like you have...
... Really liked the honesty in your video here showing mistakes you claim (I don't know any better 😂).
Yeah do more, do a dopamine one!🎉
Hope to watch you again soon!
Yep i can relate to the ,"poor" statement.lol.thanku for video.
Awesome! That would be an interesting one to perfect. How about one of the enkephalins? They're our endogenous pain killers.
Make the opposite of a pain killer
You can try making melatonin , pretty simple but very long
Small channel for no reason, very Explosions&Fire vibes I’m in LOVE. Keep up the great content👍🏻
Bro made raising a single mothers rent: the chemical
broooo
I believe their was just a report essentially disproving the idea that serotonin is linked to depression. So SSRI’s will hopefully stop being used as an antidepressant since frankly the mechanisms by which it works is not well understood and the withdrawal from them is just insanity on top of the fact that they can increase suicidal tendencies.
Fun fact: if you give a bunch of grasshoppers serotonin, they turn into locusts on an individual level. Crazy, right?
There's a wild mushroom in this area, that contains a high amount of seritonin-like chemicals. Not actually psychedelic , no trips, but if you eat those the world becomes bright shiny and cheerful.
There's still things the world at large doesnt know.
But I do know, heating starch in H20 makes gravy.
SSRIs are mediocre antidepressants. As far as anyone can tell, they work by having useful off-target effects, and the fact that they all increase serotonin in the synapse is a coincidence (like how a couple of early antimicrobials coincidentally have bright colors). Our first-line antidepressant should be a selective MAOI like selegiline or moclobemide.
If only psychiatrists and doctors would take SSRIs themselves and see what they actually do to you. All they know is what they read on their stupid medical studies. So many people are missing out on life saving medication cause they might die if they ate some cheese while taking it. Fucking bullshit.
I love all these new chemistry channels such as yours. Providing excellent content to us viewers, but also jobs to various interns at FBI
why?
I did the same extraction with the same type of pills, however just with caffeine. I basically made caffeinated bread dough with the rice flour.
I tried a vacuum filter as well and that didn't work. I also just tried boiling water, and a gravity filtration.
I think when dealing with flour and a chemical trying to extract it using an organic solvent is the best. I unfortunately did not have enough chloroform to do it, and I didn't want to boil chloroform to increase solubility.
Proper RD40 threaded masks are relatively cheap to get, and (I am not a chemist, just a safety nerd) active filters are relatively cheap to get, too. You probably know more about the boiling point of chloroform than I do, but just select a filter according to boiling point of the solvent, there are good guides out there on chosing the right class
You know what makes your science better? Working out
Sweet! Now if you could tell us how to synthesize Anabolics from Amazon supplements, that’d be spectacular. When we mix the 2, that’s where the magic happens... SHREDDED and Non-homicidal 💯
😁 jk man, love the channel, def subbed & awaiting more 👊🏽
I can tell it made you very happy throughout the process of making it :D
I think the boiling step was the mistake, although water is perhaps not very good solvent here.
some stuff you did and explained is questionable, i still like the courage and the idea tho, this is to learn about it after all ^^:
when hydrolyzing the imine with hcl, try not to use concentrated hcl (gassing with hcl works tho which is weird), a lot of the imine will be hydrolized already anyway, with funky organics like that try to acidify just a bit, aim for a ph of 6.
11:13 its a phenol, group is called hydroxy, dont worry too much about it. also why did you say acid based extraction is not as yielding, but then doing it anyway by doing an acid extraction.
"aqueous hcl can destroy tryptamine" im not too sure about that myself, tryptamines do however become easily oxidized and go through a similar way as adrenaline (become catechols, and polymer goo up, assuming 5HT is already more voulnerabl to that lol)
if you want to try it again, you can use less of the acetophenone by using a high boiling point solvent instead, as you said its quite expensive for you, why not use turpentine with 10% by mass acetophenone for example. Temperature should be measured to stay around 150C, going above will create a lot of sideproducts, going below will take ages.
imo the decarboxylation can reach yields up to 90%, isolation is the hard part.
what worked best so far was dissolving some benzoic acid in acetone, and adding that to the RM, stirring and waiting for crystallization. after that add any ether and filter your salt.
5HT benzoate should like T benzoate be almost insoluble in everything (except water and hot alcohols)
oh also, no beta carbolines, dont even know how they could form, you might have drifted a couple topics too far into the purely theoretical synthethis involving formaldehyde (and likely a reducing agent like NaBH4 :P) which however would be called "tryptolines" because they form from tryptamine and have a saturated ring. yeah
tryptamine salts that cryst out nicely: fumarate, oxalate, benzoate
forget about crystallizing the freebases, its really hard due to small amounts of tarry oxidation, chromatography and distillation is almost the only thing that can help lol
might the first stuff preciping out be the carbonate salt of the 5HT?
oh also after watching the video again, i feel like you started recording and learning/improving along i like that :P
toluene works, just has to be hot lol.
The idea of dying from consuming too much serotonin is an oddly appealing concept in the sense of how insanely ironic it seems to be
The Pharmacology of Lithium and how anticonvulsants for Mania work are quite interesting too.
gabapentin controlled my mania very effectively before i built a tolerance to the substance
@Blingy McDaddy I was on Lithium salt it caused kidney impairment and chronic toxicity. What is scary no symptoms except for excessive tiredness. My lithum was 1.4 close to toxic levels. I got dehydrated. It could have easily shifted to above-lethal limits.
@Blingy McDaddy Yes How does Lithium work we discovered it in the 1950 and don't know everything about it. It depolarizes ions at the nerves when at high dosages (replaces sodium) this explains its toxicity if you get dehydrated. It slows nerve signals and increases Glutamine, Serotonin and reduces Norepindrine. It a salt how does a salt change the sleep cycles not many drugs can do that. I hope good alternatives are developed.
@Blingy McDaddy yeah i'm on Oxcarbazepine for it now. Gabapentin was definitely more effective for me, but Oxcarbazepine feels like it sharpens my mania to a point that i'm still able to do things. I still feel like I'm about to jump out of my skin, but I'm not paralyzed by the feeling. Gabapentin flushes the whole feeling out of me entirely and replaces it with a confident mental relaxation that allows me to focus very well on whatever I'm trying to focus on
@Blingy McDaddy Often it did nothing but make me tired or edgy. It is not recommended for Bipolar 2 only Bipolar 1. I don't understand why people still consider it a gold standard when it is so toxic.
all you alchemists here make me proud, much love
love chemistry, and you seem like a decent person. subbed and cheers
I wonder how useful chat gpt could be for amateur chemists. You could get it to write up a synthesis and then try it out
That’s actually a really good video idea! Although I wouldn’t have much faith in it I’ll ask some questions tonight and see what it spits out!
@@PyrotechnicalScience I wouldn't either but its worth trying it out for a laugh
Some of the guys on sciencemadness tried it and it wasn't very good. It'll keep learning though, it would be cool to do a video on a synthesis written by it and see the results.
@@chemistryofquestionablequa6252 yeah like you say it will improve and at some point it'll use real-time Internet data. The fact it doesn't know what it's saying will always make it dubious when it comes to the truth
@@SodiumInteresting with all the politically correct restraints they've put on it, it's definitely questionable how accurate of an answer you'd get. Someone asked it if there was a nuclear weapon that would kill millions of people, but could be defused by saying a racial slur, which would it chose? Apparently saying a word is worse than millions of deaths.... The Bing chatbot seems another better, but there's a waiting list to use it.
"Welcome back everyone, today we're making serotonin" is such a funny line to me
Very enjoyable to see your suffering (sorry) but fun and interesting video!
Aww, reminds me of extracting codeine phosphate from OTC pain medication when things were dry. It got to a point where I was way more into the chemistry than the result, particularly the satisfaction of growing pretty crystals ... but maybe it both was equally. The production of serotonin in the gut is something that fascinates me as well. I have Crohn's disease, and a lot of the time, the psychiatric symptoms are so closely related to motility and almost every aspect of bowel function. After my last hemi/partial colectomy, I was left with about 20cm of small bowel, and have since struggled even more with depressive episodes and panic, and I wonder if it's a relationship as simple as the reduction in the absorption of nutriment, in that "short gut syndrome" can mess with serotonin production as well; a lot would make sense.
Thoroughly enjoyed this video (despite it being a _little_ "triggering" [I kinda hate that word - but not "yeet", that makes me feel young to hear in something I'm watching, but I wouldn't dare use it myself.]) Love, from the antipodes.
Ever hear about the latest study showing that dish detergent drying agent ethoxides strip the outer layer of the gut mucous membrane which causes leaky gut syndrome? Try rinsing your dishes after after going through the washer.
@@numberpirate Haha. Wow! I can't tell if that's possibly true or a just a great joke. I'm gonna look it up; sounds plausible ...
Though, seems like one of those things that, if mentioned to a doctor, receives a response of, "get off the internet". I'd better check this out before I go mentioning it to my gastroenterologist. Ha.
O Crocodil ? Y Russian ?
Hey uh... Got any spare seratonin? I've seemed to have misplace mine.
A natural Little walter white in training! Bravo my boy!!! Bravo!!!
Thank you so much, a personal pet project of mine has been to synthesis all the main neurotransmitters and serotonin was a bitch. I got some 5-htp stored up and can’t wait to try this. also i have that exact same hot plate, slow as fuck but it can work, does the wool insulate better than just standard aluminum foil cause that’s what i’ve always used. I did a similar reaction of tryptophan to get tryptamine but i used benzoic acid to create the benzoic salt which crashed out of solution really nicely, im not 100% sure if it would work with serotonin but if you ever try this again it might be worth a shot
I have the same hotplate as well lol i have found that if you make a bowl out of aluminum and fill it with sand to use as a heat bath it insulates better than plain aluminum
2 suggestions:
1. Edit out (delete) the first 8 1/2 mins, which you could simply summarize in 30-40 seconds.
2. Try simply "happier" rather than "more happy". Simple language hack that applies to many currently superfluous uses of the word "more".
Thanks for the video. It made me more happy...I mean, well, you know what I meant: Made me happier.
The Serotonin you made is nowhere enough to pay for the suffering you went through to make this video
all these half-assed (meant endearingly) procedures still managed to produce more seratonin than me in the same timespan
I love your video and I want to watch more! You are an awesome person and pure of heart. It would be interesting if you could synthesize adrenochrome or oxytocin. :)
Look back at oxytocin, and tell me where to even begin. They'd give you a nobel prize if you synthesized that from scratch
@TiMMY 2PHONE5 Why? Have you done it before? I mean tried adrenochrome …..
oxidize epinephrine
Earth needed the serotonin
...OXYTOCIN
I wish
Neat video, I appreciate you including all your mistakes and hangups. There are Mucuna Pruriens extracts that have become available with high L-Dopa content, might be a good place to start for trying dopamine.
Synthesis of Estradiol and Testosterone would be really helpful for a huge swath of people rn
Wouldn’t help them anyways, making DIY pharmaceuticals would definitely be a very bad idea
@@PyrotechnicalScience well the knowledge base is important, as one never knows if or when their medication of any form is going to disappear and it may also grow your viewerbase.
@@SeaforgedArtifacts we rely on China almost exclusively for medications. They could cut off the supply at any time, that's why I collect syntheses of important medications needed for things like major surgery and other life saving situations.
Maybe if he had his Ph.D. in organic chemistry. That would be very difficult
@@science_and_anonymous maybe, it would definitely be interesting to learn the process
Maybe the real neurotransmitter here is the dopamine we made along the way.
I live sometimes as If things are moving. No I don't do drugs. I just simply wake up and some days if I'm walking down the street I'll see it- and when I'm looking at the walls and ceiling I'll see it- (warp)... I don't mean to sound nuts but this is soemthing genuine that's been happening for years. I tend to zone its not great..
Thanks youtube algorithm for suggesting to me your videos!
i ate over 6,000 ecstacy pills in the late 90's and i heard that depletes the serotonin levels..i must say those were the best times of my life and had a good time every time.
I have no idea of what is going on In a science language but wow this is very interesting
Serotonin is the happiness chemical just like melatonin is the Sleepytime chemical. Or tryptophan. It doesn't give a super scientifically accurate view of the whole story... But it's a good way to summarize it for the general public
Just like how the radiator and coolant in your car engine isn't responsible for powering your car and moving it forward. But without it things go bad quickly
Really enjoying your videos and wish you a lot of luck in the future!
textbook nerd but mad respect.
This is how they teach us in school because its entertaining as fuck