Lupus nephritis - causes, symptoms, diagnosis, treatment, pathology

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  • Опубликовано: 14 дек 2024

Комментарии • 93

  • @Askify
    @Askify 2 года назад +33

    My transcript notes of the video:
    00:03
    The term lupus refers to systemic lupus erythematosus nephritis refers to the nephron the greek word for kidney and itis means inflammation so lupus nephritis refers to
    00:15
    inflammation of the kidney that results from having systemic lupus erythematosus lupus is an autoimmune disease in which the immune system attacks various parts of the body including the skin the joints lungs heart central nervous
    00:29
    system and of course the kidneys in fact about half of all individuals with lupus develop some form of lupus nephritis in lupus what happens is that some cells have their dna so badly damaged that the
    00:43
    cell undergoes programmed cell death or apoptosis and it dies this produces all these little apoptotic bodies and exposes the insides of the cell including parts of the nucleus like dna
    00:57
    histones and other proteins to the rest of the body now with lupus the immune system is more likely to think that the cellular parts are foreign or antigens and since they're from the nucleus
    01:09
    they're referred to as nuclear antigens and immune cells try to attack them not only that though individuals with lupus have less effective clearance essentially meaning they aren't as good at getting rid of these apoptotic bodies
    01:23
    and so they end up having more nuclear antigens floating around so as a result of all this b cells start producing antibodies against these pieces of nucleus which are called anti-nuclear antibodies
    01:36
    these anti-nuclear antibodies bind to nuclear antigens forming antigen antibody complexes which drift away in the blood and deposit in various places including the kidneys
    01:49
    these immune complexes can then initiate an inflammatory reaction which is known as a type 3 hypersensitivity reaction lupus nephritis is classified into various types depending on the exact site of these immune complexes and
    02:05
    subsequent inflammatory reaction the most common side of deposition is just underneath the capillary wall also known as the endothelium but deposits can also be within the bowman space of the nephron the basement
    02:17
    membrane or near the mesangio cells the extent of inflammation within the kidney can be focal which involves nephrons in just one area or diffuse involving almost all the nephrons in both kidneys
    To get the full transcript of the video with PDF screenshot notes, try Askify chrome extension

  • @Moana-y3x
    @Moana-y3x 6 месяцев назад +8

    I'm so glad i found this video. I finally understand what actually happened to me 4 years ago

    • @AdarshJain-h2q
      @AdarshJain-h2q 2 месяца назад

      are u fully cured now?....how long does you took medicines??

    • @Moana-y3x
      @Moana-y3x 2 месяца назад +1

      @@AdarshJain-h2q from the kidney problems itself, yes I'm fully cured now. I think i took medicine for about two years. But i already feeling way better and normal again after around 18 months. However i still have lupus, but it's in remission mode now, which means it's kinda sleeping and i don't really have any health problems.

  • @CassieHW
    @CassieHW Год назад +8

    this was so helpful, thank you. makes it so much clearer

    • @osmosis
      @osmosis  Год назад +1

      You're very welcome! 😊

  • @soogymoogi
    @soogymoogi Год назад +7

    My mom just got diagnosed with this (on top of sle and sjogren's). Glad there's probably not a huge genetic component 😢
    Thanks for the education.

    • @osmosis
      @osmosis  Год назад +2

      Most welcome 🙏🏼

    • @Imakerandomvideos247
      @Imakerandomvideos247 2 месяца назад

      Hey I also have both. Hope your mom's doing well.

  • @matheusgrechi2139
    @matheusgrechi2139 3 месяца назад +1

    This is a great, simple explanation. Thanks a lot.

    • @osmosis
      @osmosis  3 месяца назад +1

      Glad it was helpful! ❤️

  • @mercedes.de.losangeles
    @mercedes.de.losangeles 2 месяца назад +1

    Thank you. I think this is happening to me now. Unfortunately, the nephrologist I was referred to doesn't have an opening till April!

  • @blackbeauty7499
    @blackbeauty7499 2 года назад +4

    Great video thank you, can this only be found out by a kidney biopsy or is there other ways? I have lupus SLE and have a new urologist (my last one who was great left the hospital I’m at) he has booked surgery to check out my bladder next week… can he check out my kidneys through stretching my bladder under general anaesthetic? Oh pre-op assessment is today 🙏🏾❤️🇬🇧

    • @nancycarlos5695
      @nancycarlos5695 2 года назад

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on RUclips i come and cross Dr.Auchi on RUclips channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️

    • @Pr0ph3cy-k5z
      @Pr0ph3cy-k5z Год назад +1

      The bladder is checked with a Cystoscopy procedure.

  • @angeljohnson2835
    @angeljohnson2835 2 года назад +4

    Loved the way you teach❤💯

    • @osmosis
      @osmosis  2 года назад +1

      Thank you, Angel! 😃

  • @rehankhanzimri461
    @rehankhanzimri461 2 года назад +3

    Loads of love for Osmosis.. very nice platform for learning

  • @leaveittolefty
    @leaveittolefty 2 месяца назад

    exxcellent presentation! clear, concise. thank you!

    • @osmosis
      @osmosis  2 месяца назад

      Most welcome! 🙏🏼

  • @suki765
    @suki765 Месяц назад

    Thank you ! 😁

  • @terefesamuel7086
    @terefesamuel7086 Год назад +1

    This is helpful 😊thanks sir

  • @StelyoManhique
    @StelyoManhique 2 года назад +5

    What software is used to create this kind of video?

    • @osmosis
      @osmosis  2 года назад +4

      Hi Stelyo! Thanks for asking! Here’s how Osmosis videos are made: www.osmosis.org/blog/2020/11/27/how-osmosis-videos-are-made# 👍🏼

    • @StelyoManhique
      @StelyoManhique 2 года назад +4

      @@osmosis Thank you. I’m gonna try it out as I want to create content like this but for biochemistry and in my local language (Portuguese) because our students can’t really understand English.

    • @nancycarlos5695
      @nancycarlos5695 2 года назад

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on RUclips i come and cross Dr.Auchi on RUclips channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️

  • @newtekintl
    @newtekintl Год назад +1

    Thanks for sharing

    • @osmosis
      @osmosis  Год назад

      Thanks for watching! 😊

  • @DrNas968
    @DrNas968 2 года назад +2

    Informative video,thank you

    • @osmosis
      @osmosis  2 года назад

      Most welcome! 👍🏼

  • @mrrishiraj88
    @mrrishiraj88 2 года назад +1

    Thanks

  • @kazheali893
    @kazheali893 8 месяцев назад

    Can you tell me you edit videos? Because they are very beautiful

  • @Handle70770
    @Handle70770 2 года назад +10

    I have Lupus. It sucks.

    • @VivekKumar-hi6wg
      @VivekKumar-hi6wg 2 года назад

      I was really happy I got a recommendations of Dr Ewi1 on youtube that cured me of my Lupus diseases. I used his herbal medicine in less than a month I swiftly recovered from this disease

    • @nancycarlos5695
      @nancycarlos5695 2 года назад

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on RUclips i come and cross Dr.Auchi on RUclips channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️

  • @healthylivingeachday
    @healthylivingeachday 2 года назад

    Thank you very much 💜

    • @osmosis
      @osmosis  2 года назад +1

      Welcome! 😊

  • @valsartanay7117
    @valsartanay7117 2 года назад

    Thank you💖

    • @osmosis
      @osmosis  2 года назад +1

      You're welcome! 👍🏼

  • @sairamuqaddaskhan2562
    @sairamuqaddaskhan2562 2 года назад

    Loved it thank u soooo much♥️♥️

    • @osmosis
      @osmosis  2 года назад

      Most welcome, Saira! 🙏🏼

  • @ibnat5972
    @ibnat5972 2 года назад +2

    🤗informative

    • @osmosis
      @osmosis  2 года назад +1

      Thanks! 💕

  • @1saac_wayne
    @1saac_wayne 2 года назад +38

    It's never lupus "house M.D"

    • @VivekKumar-hi6wg
      @VivekKumar-hi6wg 2 года назад

      I was really happy I got a recommendations of Dr Ewi1 on youtube that cured me of my Lupus diseases. I used his herbal medicine in less than a month I swiftly recovered from this disease

    • @nancycarlos5695
      @nancycarlos5695 2 года назад

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on RUclips i come and cross Dr.Auchi on RUclips channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️

  • @நலம்வளர்
    @நலம்வளர் 2 года назад

    Very nice

    • @osmosis
      @osmosis  Год назад

      Thank you! 🙏🏼

  • @sweetynaiko2932
    @sweetynaiko2932 Год назад +1

    Is there any cure for this disease

  • @Mina-jz5vk
    @Mina-jz5vk 2 года назад +1

    Sheesh cool 🔥🔥

    • @osmosis
      @osmosis  2 года назад

      Thanks, Mina! 👍🏼

  • @doctortabark
    @doctortabark 7 месяцев назад

    ❤❤❤

  • @LauraW102
    @LauraW102 2 года назад +8

    That's what happened to Selena Gomez right? she has Lupus and Had to get a Kidney transplant.

    • @fook12345
      @fook12345 2 года назад +1

      yeah

    • @LinneaSanchez
      @LinneaSanchez 2 года назад

      She doesn’t have lupus, she has a lupus like disease. Maybe MCTD?

    • @annebarwick583
      @annebarwick583 2 года назад

      Yes, she would have almost died if it wasn't for her best friends donating her one of kidneys.

    • @nancycarlos5695
      @nancycarlos5695 2 года назад

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on RUclips i come and cross Dr.Auchi on RUclips channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️

  • @Trafie307
    @Trafie307 11 месяцев назад +1

    Why r u so fast ?

    • @osmosis
      @osmosis  11 месяцев назад +2

      Hi! You may adjust the video speed on the menu at the bottom of the video screen to a more comfortable speed. We hope this helps! 🙏🏼

    • @Trafie307
      @Trafie307 11 месяцев назад

      @@osmosis ok sir thanks

  • @ganardian6224
    @ganardian6224 7 месяцев назад

    Keluar agen farmasi dan

  • @ozmelkan2251
    @ozmelkan2251 2 года назад +1

    Guess who is watching 😕😕
    Just taken an exam today and verifying my answer....😥😥😥😥🙃🙃🙃🙃and it turned out wrong😕😕😕😕😕😕😕.....

    • @osmosis
      @osmosis  2 года назад +2

      Let's do better at the next one, then! 👍🏼 You may view our entire video library when you signup for a trial account at osmosis.org (we won't charge you once the trial expires) for the topics that you need that aren't available on our channel. 🙏🏼

  • @doctortabark
    @doctortabark 7 месяцев назад

    ❤❤❤

  • @oshyobass8678
    @oshyobass8678 3 месяца назад

    ❤❤❤