Extracting the spicy chemical in black pepper
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- Опубликовано: 5 май 2017
- Hey guys, this is a new series called edible chem, where Ill be able to eat the stuff that I make. For this video, Ill be extracting piperine, but let me know what you would like to see in the future!
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Nile talks about lab safety: • Chemistry is dangerous. 
Наука
"...I'll use a different spoon, just to keep my piperine clean..."
*proceeds to spill the entire yield all over the table*
I was just about to make this comment.
When I saw that I just went "now SNORT it"
I thought he was gonna do a line.
@@falvius9804 That'll get you going in the morning
@@falvius9804 "Hi, my name is "NileRed"... and welcome to Jackass!"
Extract baby oil from babies
haha, that's a good one
If you dried it you could make baby powder.
@@unclekanethetiberiummain1994 dehydrated baby
@@unclekanethetiberiummain1994 if you cooked it you could have baby food
@@right9128 dry baby
dessicate neonate
Extracting the ‘spicy’ chemical from spicy peppers.
The conclusion he comes to is ‘it’s spicy’
I love science.
@@bufferr_ you made my day :'D lmfao
Black pepper dood. Spicy peppers like jalapeños or ghost peppers contain capsaicin
no he said "it's spicy, but not that spicy"
@@Alontrle you're not that spicy
@@omnacky you wanna go I'm like the ghost pepper of this shit..kidding im a green bell pepper at best
Nile: "The piperine was super fine"
*piperine blushes*
UwU
@@pumkin610 OwO
The Piperine: Why Thank you, UwU.
Noooooooo
OwO
UwU
EwE
RwR
extract menthol from mint leaves
yes! I got vial with menthol crystal and they are amazing !
Ben Dover you eat those
You could probably get lots of it from menthol soothers. I'd say a heck of a lot more.
extract acetyl-Aldehyde from peppermint.
@Willem DaFuckedUp Willem DaFoe you are supposed to be retired.
NileRed: im lazy
Also NileRed: *spends months on singular project*
uilsoum he’s smart person lazy. So smart that they know how to put in the least amount of effort
That's why he spends months on it probably. If he wasn't being lazy he could finish most projects within a few days to weeks (excluding the time he actually has to wait for some stuff).
@CKV „Is it possible to learn this power?“
Nile - *Uses spoon to keep it pure*
Product - *spills all over table*
Nile - :0
Z🤣 poor guy
loll
The soxhlet extractor is one of my favorite pieces of glassware. It's extremely useful, even in the culinary world. I use it with ethanol (ever-clear) and ground dried ghost peppers to extract capsaicin to enhance hot sauces.
“Enhance” what kind of sadist are you?!
Scrolling through the comments and so I learned that apparently it's not called a "socks hood" extractor smh
Also, “soxhlet extractor” is so fun to say
Dear NileRed, pure capsaicin isn't very spicy because it requires a carrier oil to stick to the mucous membranes and cause irritation (aka the burning sensation). Could it be that Piperine requires a carrier oil as well? Couldn't find anything online to confirm this.
MrFibonacci You're smart.
@@Omaroka He is.
Try olive oil (xv) or black walnut oil. These seem good as they cut white(yellow) phosphorus for demos.
Probably not, as he could still taste the spiciness. What he meant by "nothing" was probably that it was ONLY the spiciness, usually in food spiciness is just one flavor amongst many, so the burning sensation has background flavors that are actually tasteable, and not just sensations.
@@rachelmoody1520 no the point is that its not as spicy as its supposed to be
takes a new spoon to keep his product clean
dumps it on the table a few seconds later xD
Not the most efficient.
13:27 "I actually took about the same amount. So i have..." dumped everything on the table yes !
Your face was priceless !
Wiki says so far circumin has not shown to do anything good for you and is overall useless, but it false-positives a lot of health tests.
Nicolas Bana YES!!!!! 😂
NileRed How much time elapsed between the "...oh." moment and the moment you were able to resume the video? Also how long until we see the cut footage?
you made pepper for people who consider salt spicy
Lmfao
@Vanargand I am Mexican that sounds worse than death for me
@Vanargand that was a joke genius
It's ok girls, you can both wear a blue dress to the prom..
@Vanargand Sennssiiiitttiiiivvveeee
He really went from "This is my science project, hope you enjoy" to "Is it possible to eat gloves?"
YOU PUT THAT in the fridge?
"oh orange juice"
*shlurp*
"Ahh my liver!"
He almost certainly has a separate lab fridge.
@@Karreth and who drinks orange juice from a beaker with plastic wrap over it?
Caleb Angell how do you store your orange juice? That seems perfectly normal
@@calebangell77 do... do you not?
liver hurting juice
Nile you have made such progress....
And even when you had a low number of subscribers, you never lost the quality of the videos... Keep up good job
GayRainbow Unicorn xx i wonder if he will do a face reveal for us when he hits 150k 😍
he also did a face reveal in the green chemistry video
And he is actually cute as hell...>_>
he is..
What? He's at the end. And has been in a lot of his recent videos.
7:39 - Me when I do the dishes
so good but so few likes... same tho
nice.
When im wiping my ass
@@jakep111 ahahahah. you got me "waking up my parents in the middle of the night" laughing
When my dog is done licking my plate
Nigel: I’m lazy
Also Nigel: *does everything else he does on his two channels and is one of the most productive RUclips creators I know*
I'm four semesters into my chemistry bachelor and we just started with the organic lab last Monday and boy - my appreciation for your videos has easily quadrupled since then. Organic Chemistry is so tedious and takes so long and you go through all the hard work just to present us the cool stuff condensed into 10-20 minutes.
Recommending you to all my pals from university now, so they can see some lab techniques btw ^^
Same boat hello!
What're you doing with your degree nowadays?
@@zrspangle He has become Heisenberg, Making coainer
Chemistry degrees are useless unless you get a masters
@@blank888 what I’m tryna do. You’d be amazed how easy it is for some stuff. Nothing good is easy but there’s some hallucinogens that take 6 hours and 3 separate easy to find chemicals to extract. Life is sometimes awesome
Oh my god your expression when you dropped it was priceless, so sweet
What are thirsty girls doing here? This is a science video
Lil Borki girls can thirst for cute science boys and science, there’s no limit on the thirst that is possible
@@wetowl479 how dare someone express a feeling
thirsty? drink the chemicals
he doesn't have facial expressions.........ever
Nile 5 years ago : Let's extract spicy chemicals from food
Nile now : Building a nuclear reactor from scratch in his garage
in 1 minute
now he creates the spicy chemicals
Drinking game: take a shot every time he says “isopropanol”
*take a shot of isopropanol every time he says "isopropanol"
We'd all die from alcohol poisoning before the end of the video
@@ChiffCharang take a shot of whatever alcohol he names when he names it. You might even live
Gregory Khvatsky methanol it is👍
I tried counting every time he said “isopropanol” in the video (not counting alcohol) and it looks like you’ll be drinking 12-13 shots for the game
It makes sense that it doesn't taste like anything. The piperine only interacts with heat-sensitive membrane proteins and not other proteins related to taste.
So it's basically just concentrated "heat"
apparently the fact that it doesnt dissolve well either takes a lot of taste away.
NileRed is it possible to make a water soluble salt of piperine
Holdin McGroin i did not understand ... where did you learn about interactions of piperine? biochemistry??
yes
Holdin McGroin can u explain me what he said at 2:10
You have set a dangerous precedent by tasting your product in this series; The viewers will demand more sacrifice. Good Luck
*eats all the piperine*
"what does it taste like"
"P A I N"
When doing a soxlhet extraction, I would always put my material in a reagent tube made from fine mesh cotton, and plug it with cotton - this would enable you to powder the pepper corn as fine as you wish, increasing the yield
Or use paper filter tube. These are also food grade and are just hassle free to use
Never eat or drink in lab
Nilered HOLD MY FLASK
He went to the kitchen to eat it.
high school chemistry: having a bag of sweets next to your titration setup because it just takes forever
Hold my toilet paper moonshine
Already excited for this series
9:30 Don’t confuse the fresh orange juice with the pepper extract, potasium hydroxide, isopropanol and water
Thank you for keeping 13:26 in, you point at it briefly with an "oh shit" look and gesture and then you move on like a pro. 🤣 I love your channel!
Yay! Someone is finally doing edible chemistry
Acrimonious Oxide all chemistry is edible ;) you just might not want to eat it
Acrimonious Oxide what codys lab has been eating indium and whatnot for years???
Kevin Crossland Oh yeah I forgot. I remember he drank cyanide, mixed KOH into drinks,...
+Kevin Crossland He hasn't been "eating" indium, he only chewed it like chewing gum. Even if he did it's non toxic so meh.
That's MDA, Ecstasy is MDMA
Fun-fact: Cosmetics industries uses capsaicin along side with epiderfill on lipsticks in order to cause a minor irritation that make the lips grow in size by just a little bit.
Also, as a chemist undergraduate, i love your videos and i forbid you to stop making them.
Alberto Terk i am in second year can you explain me what had he done?
As the hot solvent recondense on top of the crushed pepper it pass through it and carries the piperine with it
Hes just using some fancy pants glassware(Soxhlet extractor) to keep things simple and easy.
You can alternatively extract by drag if i'am not mistaken, but as he stated is much more 'labor intensive'.
That's pretty much it. The Soxhlet extractor, keeps recycling the same alcohol, so that he ends up with a more concentrated solution at the end, than if he just heated the pepper in a large quantity of alcohol and boiled it off.
The extract works as a d distillation unit, so the the evaporated alcohol is mostly pure when it condenses at the top. It's hot and as it drains through the pepper, it dissolves the piperine.
When the siphon tube fills to the top, it quickly drains the solution with the dissolved piperine, and the cycle repeats.
The siphon tube is working with the same principle as a flush toilet.
How are you doing now, 5 years later?
I'm actually learning from all this, this made me want to take some classes and i'm also doing research too on all of this. Thank you i've never been this happy in a while, you're such an amazing inspiration.
"Tastes like nothing." - NileRed
"Tastes like emptiness"- HTME
Have you considered dissolving the piperine in some sort of cooking oil and tasting it afterwards? I guess due to the poor solubility there's no chance for the piperine to unleash its full potential on your receptors..
Edit: Btw - great format! :)
Very jealous of all the glassware/equipment you have access to!
It's all available online....
www.coleparmer.com/i/kimax-601000-0624-soxhlet-round-bottom-flask-500-ml-1-pk/9903766?PubID=UX&persist=true&ip=no&gclid=CjwKCAjwhOvPBRBxEiwAx2nhLisZDN8itw3PVInSDfXM79mdCy-WjCZCr_okYx7_CvRYMHrP7HCb1BoCf70QAvD_BwE
Very jealous of how intelligent this fifteen year old is.
@@drippingwax he is 28 this year
@@Weaseldog2001 Whoa! You can buy things on the internet? WOW! I never knew! Without a doubt, he's referring to the price. Smug, or ignorant. Either way, your comment sucked. Just thought I'd let you know.
@@genericalfishtycoon3853 I'm glad I could help you.
Yes, posting links to where you can buy things, does suck. I can see how you'd hate people who post links.
Love this! Current food science student and chef, and we haven't done anything like this in the lab...yet. Keep it up man, this kind of inspiration keeps me going through midterms and long reports - reminds me why I chose this field.
2:01 this is the moment i realised traditional indian cooking methods have so much scientific advancements in them
The quality of your work and videos are steadily increasing. Please keep making them, they are super fun to watch.
0:44 Chavicine, AKA: "essence of English bogan".
His videos are both relaxing and educational, his consistency with the editing is so satisfying. Easily one of my favourite RUclips channels.
Dude, you're an inspiration. Thank you for all your videos and demos.
Wow. The color, cleanliness, and order to your kitchen in this public appearance could speak volumes.
I get the feeling that you had a highly structured upbringing.
Sounds like a great idea for a series!
The explanation of the soxhlet extractor was super cool!!! I love your channel so much~!
THIS is the video that made me sub. oh yea, the extracting citric acid video too. Great job!!
13:15 "impressive spoonflip"
I wonder how coffee would taste if brewed with a Soxleth-extractor.
Full immersion + filtration. I would guess it’d taste like what you’d get from using a clever dripper.
This gives me an idea for a video *runs to cupboard and has neither a clever or a Soxhlet extractor*.... never mind
That was my thought too. But reboiling your coffee over and over will make it terrible... perhaps not if you do it at low pressure so it boils cooler.
That is called a perc pot. Brewing coffee with a perc pot is an art. You have to stop it at the right point or it gets bitter.
Your videos are so entertaining because of the professionalism in hobby chemistry -- keeping so chill about spilling most of your product!
Went from food grade to making grape soda from nitrile gloves.
Seeing crystals form never gets old!
It's been two years, and there is no response from Wei. What have we done?
FINALLY, SOMETHING I CAN EAT WITHOUT GETTING POISONED IN 9000 DIFFERENT WAYS! I would love to see more of these Edible Chem videos in the future man, I really enjoyed it!
Thanks, more to come for sure!
Cheeser100 The isopropanol is a bit toxic, it is an irritant. It should have evaporated off though. My point is that in theory it could hurt you in one or a few ways.
improperly cleaned glassware would be the kicker ;)
What kind of things do you wish to eat that are not already available to cheaply buy ?
Like he says in the video, the pepper remained peppery, and the extracted crystals were pretty much tasteless.
Guardian of Bullshit. Confirmed.
I really love this channel. Keep up the good work.
I like this part of your channel. Interesting to explore things we consume.
9:36 mmm orange juice
Best chemistry videos on youtube. Thank you Nile!
Great videos keep it up and stay confident WE BELIEVE IN YOU !!!!
Anyone else just enjoy the fluid movement of the bubbles?
its so calming!
You are literally so adorable please show your face more
Hes a part time model, on the side.
@@lt-devilwolf3871 Incel.
@@derpinbird1180 LMAOOOO
Cryptic Wolf3391
Jesus, shut up she’s just complimenting someone.
@@Girthopkins omg what happened here
Lmao I thought you complimented the Piperine at 9:50 XD
I know this is years later, but I want a t-shirt that says 'Keep my Piperine Clean' . Found your channel not long ago and I love the work you do. Binge watching NileRed for quarantine. Woo!
8:12 At first, I wanted to note that both enantiomers are of course reacting exactly the same with non-isomeric compounds, but then I realized that Chavicine is actually a geometric isomer of Piperine.
Now we know you do exist outside of the lab! I'm really excited for the rest of this series.
ha, i do have a life outside of chem (surprisingly).
NileRed how old are u btw?
"I will only be using food grade materials"
Procedes to mix red bull and acid to take out the caffeine
Great educational entertainment as usual, Nile! :)
I love Soxhlets 😄 They're super convenient, awesome to look at while extracting and generally have a super smart design. Only used it once tho (for piperine as well). But I used a cellulose based extraction tube instead of cotton. The solvent passes through the pepper a lot nicer and it was easier to remove the pepper after the extraction was finished.
Extract the depression from my brain!
Sorry there's not enough brain to work with. The depression yield would be too low.
@@mikehunt4048 too low for what? Good try, but not a very well thought out quip.
Dat funny haha you sad and said joke!
Kratom and dxm are nice but addiction can lead to dependence which is absolutely horrible.
@@NoodlePastie what
13:26 HIS FACE WHEN IT FALLS I CANT
Wat
Wat
Wat
Wat
Wat
5:00
...It’s a fancy science percolator
Great series bro counting on it
13:51 nice line you got there on the table
"It actually tastes pretty horrible.."
the time lapse crystalization was incredible!
I'm excited for the Capsaicin one! I'm a spice junkie lol I've considered buying pure cap because of how much I love spice. Add a crystal to my food when 5 ghost peppers won't cut it lol
Nile is too young to have all this knowledge xDDDGood job NIle, keep up the great work!
13:20 he spilled it oof ^_^
i don't even like chemistry but i just fell in love with your videos they're so interesting I've watched everything
I love this channel it sum how gets to take a nap 20/10
This is late but:
Use a BURR GRINDER for black pepper, or in general, if you want a controlled fineness to your grains. Blade grinders just chop in a mess.
got to have my daily dose of chemistry
Mikko Mallikas Yessss
It makes sense now why my mom always tells me to include black pepper with tumeric and milk when I'm not feeling well
I really love your videos brother !!! 🙏🙏🙏 have a great day !!!
What is the point of this comment
@@longsnake5758 to say that they like his videos
Can you make MSG?
Ill look into it. There might be an interesting way
Yes, make e621.
ahh... I see... Ramen is just the generic name for MSG
+
ThunderGirl Emi monosodium glutamate
13:28 is fricken hilarious im dying😂😂😂🤣
For the extraction from fine powders you may want to use a soxhlet thimble or capsule. These things leave enough room on the sides to let the solvent drain,while offering the increased specific surface area of fine powders. They are commercially available, but you should be able to make one yourself.
These videos are always so anticlimactic. I love it.
"to help me out because I'm lazy.." HAHAHHA. I really love your attitude! 😍😍
We did this in organic chemistry last fall! Was really fun to do. While checking the melting point to see how pure it was, the entire lab coughed like crazy, and one of the lab engineers had to step outside to get some air :P
That last background of the Chromyl Chloride is an amazing picture. I would love to take pictures like this all day long!
If you don't have any extractor thimbles, you can use scrunched up coffee filters. Just make sure that the reflux condenser drips inside the top of the filter for best results. As long as the top of the filter is above the top of the siphon, it will work fine and the grind of your powder will not be as critical.
Extract curcumin from turmeric :)
what about extracting the thing that makes ginger so harsh
Their souls? You'd probably need a priest for that
@@pegleg2959 I actually have the spawn of Satan in my cupboard
She wasn't harsh to me.
ahh really interesting i love learning about this type of stuff thanks! :))
Dude I study chemistry in the 5th semester. Guys like u made me do it. Thanks, nice video. Keep them up :)
"To help me out, because I'm lazy", made me laugh.
3:28 “get rid of the larger pieces” *ad containing scantily clad anime girls plays*
nigel: i will only use clean glasswares and food grade chemicals in this series.
me: ok. WAIT WHAT?
I love your monotone face during the whole thing😂😂
Holy shit!
I have that exact same coffee grinder!
dang, lookin good there
I remember trying to do this in High School during lunchtimes! We didn't have a soxhlet extractor so we just had to boil it under reflux for a few hours, and we had to order in KOH (which didn't arrive in time), but I did get a few of those crystals
with very fine powders, acid-washed sea sand can be mixed in with it, this allows the solvent to flow through even very fine powders, which increases the extraction enormously
finely ground substances naturally increase the yield and the sea sand allows the solvent to penetrate the powder very well