Looking for Answers in the Skull of a Zebrafish

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  • Опубликовано: 27 авг 2024

Комментарии • 296

  • @jessebob325
    @jessebob325 2 года назад +269

    I like Hank's quiet voice. It's such a change from his normal excited voice it makes me smile.

    • @adisfajic9074
      @adisfajic9074 2 года назад +3

      First of all amazing as always and ty Hank, but Jessebob i came here to actually say the oposite i like more the excited Hanks voice :)

    • @leogama3422
      @leogama3422 2 года назад +12

      I know it's Hank, but sometimes I still think it's another person. I have to repeatedly convince myself

    • @Le_Mouton_Noir
      @Le_Mouton_Noir 2 года назад +4

      The video itself is amazing but I can't stand anymore the endless flow of speech in all the videos these days.
      The 9:43 minutes of footage was covered by 9:40 minutes of uninterrupted speech, that's tiresome

    • @blasiuspolo3836
      @blasiuspolo3836 2 года назад +4

      THAT'S HANK?!

    • @jessebob325
      @jessebob325 2 года назад +2

      @@blasiuspolo3836 I know, right? I had listened for months when it suddenly came to me. 😳🤭🍻🥓

  • @cutlerphillippe
    @cutlerphillippe 2 года назад +163

    As a researcher working with micro-scale imaging, I find these kinds of both beautiful and medically relevant results inspiring.

  • @annajoules3033
    @annajoules3033 2 года назад +289

    I can’t believe this is the humble zebra Danio that’s so common in aquariums! I’d love to have a print of those photos, they’re truly beautiful 😍

    • @patldennis
      @patldennis 2 года назад +11

      it's also heavily relied upon in evo devo research (evolutionary developmental bio) as is the Aftican clawed frog which is also common to the aquarium hobby

    • @leogama3422
      @leogama3422 2 года назад +6

      I think scientists were initially interested in its zebra stripes pattern forming. It eventually became so widespread in labs that was turned into a "model species" for research (the simplest vertebrate of them)

    • @Ghryst
      @Ghryst 2 года назад

      CTRL + Print Screen, newb

    • @sugatasen1997
      @sugatasen1997 2 года назад +3

      We find these zebra danios swimming in even the most transient watery rice or paddy fields here in Bengal. They're extremely resilient and active little fish, both in the wild and in aquaria.

  • @ren3171
    @ren3171 2 года назад +3

    Im very happy that the researchers anesthetized that fish and got the cross sections via optical means rather than killing the fish to do their research.

  • @KH-mx7bg
    @KH-mx7bg 2 года назад +41

    Love this video, it's a nice break from microbiology. I use transgenic fluorescent zebrafish for investigating human craniofacial birth defects, so I appreciate a video like this showcasing what we do. When you tell people you're doing genetics work with fish to learn about human disease, it sounds really boring. I'll use this video as a visual aide now.

  • @driverjayne
    @driverjayne 2 года назад +83

    Every other creator on the planet should take note that THIS is how you do a sponsor video! Beautifully crafted, relevant to the channel theme AND seamlessly integrated. VERY well done.

    • @LANCEtheBOIL
      @LANCEtheBOIL 2 года назад +3

      What no " raid shadow legends"

    • @Le_Mouton_Noir
      @Le_Mouton_Noir 2 года назад +1

      Yeah maybe but matter of fact the 9:43 minutes of uninterrupted speech is tiresome.
      Everybody can make a very nice good quality video but speaking non stop is ruining it, especially when you don't have the voice of Sir David Attenborough's

    • @Stettafire
      @Stettafire 2 года назад +1

      And no VPN BS

    • @Stettafire
      @Stettafire 2 года назад +3

      @@Le_Mouton_Noir Dude, you're talking like 9min is a long time.

  • @ariochiv
    @ariochiv 2 года назад +29

    The choice of colors and contrast reveals some solid artistic sensibility. Congratulations on the recognition to the photographer.
    It's interesting how the lymphatic vessels follow the pattern of the scales down the sides of the body. Makes sense, just not something I would have thought of.

  • @animalpeeps
    @animalpeeps 2 года назад +28

    The 3D model of these images are literally how I (try to) imagine life and the physical world as. Never knew there were these detailed 3D models - I'm seriously so mind-blown!

    • @leogama3422
      @leogama3422 2 года назад

      For a couple years we have "real time" (time lapses) 3D models of live cells/animals

    • @jamesdriscoll_tmp1515
      @jamesdriscoll_tmp1515 2 года назад

      The semiconductor industry uses the image stacking technology to examine the test fixtures used to test microchips. The process is actually easy, with a little practice.

  • @vlogbrothers
    @vlogbrothers 2 года назад +24

    This is my kind of party. -John

  • @scotttod6954
    @scotttod6954 2 года назад +34

    This is amazing! These people who come up with new ways to see the world are on a whole other level. I am in awe of it.

  • @rageraptor7127
    @rageraptor7127 2 года назад +3

    Something about having so much life on our planet. Knowing it’s in the very soil and air we interact with. I find beautiful.

  • @project.eutopia
    @project.eutopia 2 года назад +14

    Seeing immune cells moving through lymphatic vessels in real time (7:26) in vivo is absolutely incredible!

  • @jessicaclakley3691
    @jessicaclakley3691 2 года назад +41

    Omg, absolutely stunning!! I couldn’t take my eyes off the gorgeous images

    • @jakobraahauge7299
      @jakobraahauge7299 2 года назад +3

      Absolutely!
      Had to watch it on the tellie after having a look on my phone 👀
      And Hank has a wonderful voice! So good on some nice loud speakers!
      If you haven't watched the first episodes yet it is absolutely brilliant work, despite the fact that the latest updates on the equipment are wonderful!
      Loads of love from Denmark 🤗

    • @jessicaclakley3691
      @jessicaclakley3691 2 года назад +1

      @@jakobraahauge7299 I need to watch them on a honest to goodness television! I can only imagine how entrancing they would be considering they cast such a magnificent spell even in small format

    • @jakobraahauge7299
      @jakobraahauge7299 2 года назад +1

      @@jessicaclakley3691 It's amazing like that! As good as David Attenborough!! 😍

  • @nautilusproducciones1040
    @nautilusproducciones1040 2 года назад +23

    GREETINGS FROM CHILE - I LOVE YOUR WORK, YOU SAVED MY QUARANTINE. Weed + Journey to the Microcosmos RECOMENDED.

  • @ProjectPhysX
    @ProjectPhysX 2 года назад +65

    I have seen the cut spinal cord of a Zebrafish regrow after 3 days. I have no idea how they do it, but unlike humans they can fully recover their neurons.

    • @LANCEtheBOIL
      @LANCEtheBOIL 2 года назад +10

      It's not just zebra danios, I do a lot of fishing and have caught multiple species that at one point were literally broken yet survive and are fully functional ( kinda)

  • @marisanya
    @marisanya 2 года назад +12

    I was part of a developmental biology lab recently that used a close relative of Zebrafish, Cichlids, as a way to try and understand monogamous behavior in-situ. By staining certain pathways in Cichlids and then comparing those pathways to Zebrafish's ones and scouting for differences, we're in the early stages of understanding why monogamy might arise physiologically. Zebrafish and their kin have a lot of use in science!

    • @emb7854
      @emb7854 2 года назад +1

      Hasn't this already been explored with pair bonding vs tournament species?

  • @desmontube
    @desmontube 2 года назад +3

    This video is a whole experience, I can’t believe how much time my jaw was dropped. Just amazing

  • @runs2288
    @runs2288 2 года назад +3

    Thank you, Hanks, for the beautiful clip, the sound is tidy, everything But it makes you feel like you are in another world

  • @Ninth_Penumbra
    @Ninth_Penumbra 2 года назад +5

    Extraordinary. The aesthetic detail is stunningly gorgeous, but the implications of this imaging technique & all the scientific discoveries captured within this single (composite) microscopic photograph, are wondrous indeed...

  • @Her_Viscera
    @Her_Viscera 2 года назад +4

    I have a school of Zebra Danios and I breed them from time to time, they indeed lay eggs when I turn on the lights every morning 😅

  • @hipopickle2216
    @hipopickle2216 2 года назад +52

    This has to be my favorite video by you, I can't wait to see how your channel will progress overtime, keep up the amazing work

  • @gamedirection_us
    @gamedirection_us 2 года назад +4

    I've been watching these videos for weeks now and just now learned this was Hank Green!? WTF, how does this man keep showing up in my RUclips feed. The true master of science and learning videos of the 2010's!

  • @texxstalker
    @texxstalker 2 года назад +1

    Simply just beautiful. Thank you for the trip Hank!

  • @EmilyJelassi
    @EmilyJelassi 2 года назад +2

    This picture of the zebra fish is definitely art and is absolutely beautiful!!

  • @areside
    @areside 2 года назад +1

    I study zebrafish and have worked on similar fluorescent imaging projects...SO awesome to see this research presented so beautifully!

  • @Leeuwver
    @Leeuwver 2 года назад +2

    As a chef I’d like to see yeast and lacto fermenting bacteria. This channels amazing I love it

  • @milchesarreal6964
    @milchesarreal6964 2 года назад +1

    What a marvelous image!
    I honestly never knew that about the humble zebra fish, something so small packed something so extraordinary.
    Science is amazing!

  • @glennberry4829
    @glennberry4829 2 года назад +3

    I'd hoped the competition would get some of the images into public domain so we could legally copy and use them (as, for example a desktop image). It doesn't, so all the competition images are copyright protected unless out of copyright for other reasons. Most photo competitions don't do that, but a few do. Anyone know if a microphotography competition that does?

  • @ArtemisAndromeda
    @ArtemisAndromeda 2 года назад

    Not just something new or beautiful, but NEAUTIFUL

  • @Cillana
    @Cillana 2 года назад +1

    0:40 Little kid: "What are those two fishies doing?" Adult: "Uhh... they're dancing... yeah, that's it... 😅"

  • @jakobraahauge7299
    @jakobraahauge7299 2 года назад +15

    Thank you Hank!
    Lovely voice work - I really do appreciate that! The best thing of Journey to the Microcosmos used to be the beautiful speak, despite the amazing footage, exquisite editing, and intriguing topics! I am glad to hear you give a little ech of those magical first speaks!
    🤗
    And the rest of you - fantastic work! Thank you guys! 😙✨

    • @mrslinkydragon9910
      @mrslinkydragon9910 2 года назад +3

      I dont like him on scishow, use to but not anymore. way too over the top and obnoxious. Here however 👌

    • @jakobraahauge7299
      @jakobraahauge7299 2 года назад +1

      @@mrslinkydragon9910 early Journey was just beautiful! Hank branched out to Tik Tok - to bring in a new crew perhaps, or just because life happens and we find new paths
      can't disagree with you tho

  • @mryellow4633
    @mryellow4633 2 года назад +1

    Most amazing they didn't add 20 seconds of buffer to make the video 10+ minutes :O I've learned so much from Hank and John Green, it truly shows they are in this to spread knowledge-profit is a side concern.

  • @mickcarson8504
    @mickcarson8504 2 года назад

    I love the Zebra Danios. My favourite little darlings in my aquarium. I love also the Cardinal Neon. Beautiful fish that help me healthy.

  • @rgibson7305
    @rgibson7305 2 года назад +1

    "...for obvious...stripe related reasons." I

  • @MaryAnnNytowl
    @MaryAnnNytowl 2 года назад

    Such beauty just from a small change in the light put on it! Thank you!

  • @Cosmiccoffeecup
    @Cosmiccoffeecup 2 года назад +3

    Simply breathtaking.

  • @CatsAndPokemon
    @CatsAndPokemon 2 года назад +2

    i am so excited I'm alive right now and able to witness these amazing discoveries..

  • @mrfosilman
    @mrfosilman 2 года назад +5

    Funny how those zebrafish decided to spawn while the video recorded.

    • @Sara3346
      @Sara3346 2 года назад

      Don't they spawn daily?

    • @mrfosilman
      @mrfosilman 2 года назад +2

      @@Sara3346 Not really. Usually zebrafish prefer to spawn at night, and normally it takes two weeks for a female to develop more eggs.

  • @daniell1483
    @daniell1483 Год назад

    The images in this video are simply stunning. From the Nikon photography competition, to the 3d model composed of 2d images, it just reminds me that the future is here today. Seeing a 3d reconstruction of a living organism without invasive imaging just blows my mind, as it is something I'd expect to see in Star Trek or something. Our age has its problems to be sure, but there is no other time in human history I'd rather live in. Scientists from just a century ago would say we've discovered magic; what will we have to say of the people in another century or so?

  • @genexxer1
    @genexxer1 2 года назад

    Beautiful and beguiling. On the one hand, majesty of creation, on the other, the nefarious possibilities.

    • @BeckBeckGo
      @BeckBeckGo 2 года назад

      Somebody read Square!

  • @seaham3d695
    @seaham3d695 2 года назад +2

    The diatoms!!! Oh my god!!! We need a new video every day! Much love

  • @Hallands.
    @Hallands. 2 года назад

    Blown away completely! Did you notice a pair casually mating and spawning at the start of the sequence?

  • @lourias
    @lourias 2 года назад

    SPECTACULAR!!!! The florescence of the Zebra fish was truly moving!

  • @beansabina3281
    @beansabina3281 2 года назад +1

    Nice to hear your calm 'Grown up' voice again: I've missed it!

  • @GGGG_3333
    @GGGG_3333 2 года назад

    I have been a subscriber for several years now to scishow and (more recently to this channel), but I never could hear Hank's voice in this channel and only realised that it is him after he said it in this video. I am mindblown right now.

  • @FayeFahrenheit
    @FayeFahrenheit 2 года назад

    These are some of my favorite fish to keep. They are friendly and goofy and fun.

  • @mcstabba
    @mcstabba 2 года назад +2

    I though this was gonna be about the third eye of zebrafishes and the relation to our pineal gland, another time perhaps. This was intresting too! Beutiful images as well.

  • @1.4142
    @1.4142 2 года назад

    Art and science go hand in hand.

  • @gebeleysis
    @gebeleysis 2 года назад

    This channe is an island of calm in a turbulent internet. Thank you.

  • @Darkchylde50
    @Darkchylde50 2 года назад +1

    I had no idea this was a Hank Green voice over much less video! This version of you compared to TikTok & SciShow is massive! Mind blown! Me gusta 💯😎🔥

  • @jefferywise1906
    @jefferywise1906 2 года назад

    Excellent presentation, thanks Hank.

  • @KessuPutte
    @KessuPutte 2 года назад

    One of the most gorgeous photos I've ever seen. Absolutely beautiful!

  • @bigbrady2244
    @bigbrady2244 2 года назад

    Perhaps your best video yet

  • @nicholasgarrett8594
    @nicholasgarrett8594 2 года назад

    I watched the video, and then immediately shared a link with three fellow nerds! Great video!

  • @deathsnitemaresinfullust2269
    @deathsnitemaresinfullust2269 2 года назад

    😯 That's an Absolutely Brilliant image of a Zebra Fish, no wonder why it won.
    It's just So Amazing.😄👍

  • @mlgiggleman9786
    @mlgiggleman9786 2 года назад +1

    Absolutely fascinating. The art appreciation wasn't that important to me, anyway. But the information was incredible. All the different structures revealed were just amazing.

    • @stillnobuddy
      @stillnobuddy 2 года назад

      Perhaps the beauty of life is what makes it art.

    • @mlgiggleman9786
      @mlgiggleman9786 2 года назад +1

      @@stillnobuddy Good point!

  • @Alien590
    @Alien590 2 года назад

    It is really awesome to see as I currently work with zebrafish Danio for my master thesis! :)

  • @AV1461
    @AV1461 2 года назад +1

    Can you believe I've been watching this channel for over a year and didn't know this was Hank Green, until he said his name now?! Only then I associated the voice xD. I watched SciShow and CrashCourse for such a long time.

  • @ByrneBaby
    @ByrneBaby 2 года назад +1

    That had to be one of the smoothest sponsor shills I've ever seen. Feels disrespectful to call it a shill tbh lol

    • @malcontender6319
      @malcontender6319 2 года назад

      Pages of comments and you're the only one mentioning the ill shilling. Well spotted.

  • @RDLondon2023
    @RDLondon2023 2 года назад

    So cool after Antonie van Leeuwenhoek these microscope videos are still from a lot of Dutch people.

  • @Troy-ol5fk
    @Troy-ol5fk 2 года назад

    these scales look so cool

  • @PACstove
    @PACstove 2 года назад +1

    I always wondered if a transparent fish got big enough to fillet, would you grill it up and it would be a clear fish you eat for dinner?

  • @dannileigh6426
    @dannileigh6426 2 года назад

    Woah! That was so beautiful and awesome in the fullest meaning of the word!

  • @crylune
    @crylune 2 года назад +1

    I'm so glad I found this channel.

  • @volmyk6196
    @volmyk6196 2 года назад +2

    you should also check out work of Ertürk Lab from Helmholtz Zentrum München. they developed DISCO clearing techniques to make transparent mice for imaging

    • @limiv5272
      @limiv5272 2 года назад

      Are the mice bald? I'd imagine the hair gets in the way

    • @volmyk6196
      @volmyk6196 2 года назад

      @@limiv5272 As I understand, fur must be gone after a mouse is treated with all those solvents. Or they just use furless mice, Im not sure.

  • @s.n.8128
    @s.n.8128 2 года назад

    I honestly had no idea it was Hank Green behind the voice. No wonder i find these videos awesome!

  • @SB-qm5wg
    @SB-qm5wg 2 года назад

    nikonsmallworld = my wallpaper slide show

  • @grahamrankin4725
    @grahamrankin4725 2 года назад

    Nikon small world competition has inspired many students to pursue careers in science

  • @bobthegoat7090
    @bobthegoat7090 2 года назад +1

    I hope they have a budget competition where amateurs have a chance, so they don't have to battle with researchers that have a $5.000.000 microscope.

  • @benjamintice6400
    @benjamintice6400 Год назад

    Watching in 2022 when we found genes that could regenerate hearing in Zebrafish. Truly in awe of nature.

  • @gibberishname
    @gibberishname 2 года назад +1

    so flippin cool

  • @alexandrefurtado3469
    @alexandrefurtado3469 2 года назад

    Always exceptional. A contribution to humanity - images and content (an aesthetic scientific scholarship - very rare)

  • @_Solaris
    @_Solaris 2 года назад

    Hank Green narrates this? It's a pleasant change from the usual commercial mania of Scishow.

  • @Mythreesons137.
    @Mythreesons137. 2 года назад

    Confocal creates a depth of field by stacking the images

  • @depressedhombre3387
    @depressedhombre3387 2 года назад

    Wow, my favorite fish ever. You can keep a school of these guys alive in a red solo cup for over a day. Not that you should try, they’re just super hardy and lively fish

  • @badkarm4
    @badkarm4 2 года назад

    Thank you sir, they choose a good judge. 👍

  • @planetmario
    @planetmario 2 года назад

    STUNNING

  • @joyglocker8318
    @joyglocker8318 2 года назад

    I like your style: poetic and beautiful and interesting. Thanks.

  • @bobthegoat7090
    @bobthegoat7090 2 года назад +3

    Researcher 1: How do I get microscopic images of a zebra fish.
    Researcher 2: You just slice it up and put it on a slide. I kill thousands of mice and rabbits to get my results.
    Researcher 1: Nah. I am just going to put it under anesthesia and set it up in a very complicated setup.

  • @tatoverde9312
    @tatoverde9312 Год назад +1

    Would you address in one of your shows, the artifacts in fixed microscopy and electron microscopy? Artifacts resulting from physisical/chemical changes as a result of the slide preparation and use of dyes?
    What is the impact of those artifacts on the development of thesis and theories? How to validate them?
    Thank you.

  • @kmcsciguy
    @kmcsciguy 2 года назад

    This is incredible

  • @yddishmcsquidish3904
    @yddishmcsquidish3904 2 года назад

    I'm genuinely surprised this channel hasn't hit 1mil yet

  • @instaperil
    @instaperil 2 года назад

    Truly breathtaking

  • @stephanieparker1250
    @stephanieparker1250 2 года назад

    The termite gut … WOW! 😲🙌

  • @oogooboggins5956
    @oogooboggins5956 2 года назад

    How have I never realized this channel was voiced by Hank Green???

  • @km6832
    @km6832 2 года назад

    Just found this channel and this is the coolest craziest shit ever

  • @technoraptor7778
    @technoraptor7778 2 года назад

    There you go getting me inspired for art again

  • @mmerritt143
    @mmerritt143 2 года назад

    This is remarkable.

  • @mondraymondo
    @mondraymondo 2 года назад

    I love these fish, i used to keep them and they happily breed in my tank :) very active and lively too

  • @GryphonGamerBR
    @GryphonGamerBR 2 года назад

    That's the most beautiful thing I saw today.

  • @thelaughinghyenas8465
    @thelaughinghyenas8465 2 года назад

    Such a cool video. Great and relaxing video with such incredible images. I am so glad you got a sponsor like Nikon.

  • @mondprasident6932
    @mondprasident6932 2 года назад

    That blew my mind.

  • @bigxberzon
    @bigxberzon 2 года назад

    KNEW IT WAS GOSH DARN HANK GREEN

  • @thanos879
    @thanos879 2 года назад +1

    All this time I didn't know this was hank green 😂

  • @yland6003
    @yland6003 2 года назад +1

    Genomes are really crazy because we can share genes 🧬 with other animals, but how those genes are expressed vary between individuals of different species. Like how we share about 60% of our DNA with bananas 🍌 yet we are vastly different. Also my pet bird has color mutations that cause freckling patterns and lighter colored feathers. I have blonde hair and freckles and we also share about 60% of our genes 🧬.Obviously it’s like comparing apples to oranges, but if you look close you can find similarities between different animals and I think that’s cool! Nature is amazing!

  • @onegreenev
    @onegreenev 2 года назад

    Oh yes, the Zebra fish. The fish that can live in 110 degree water when all others are cooked. Learned that from a failed fish tank heater. Heater failed on and the water was 109 degrees and all but the Zebra fish were cooked. Amazing little fish.

  • @mohamedlotfi982
    @mohamedlotfi982 Год назад

    WOW, JUST WOW.

  • @FredSena
    @FredSena 2 года назад

    Casper version of everything! I better be careful with what I wish tho...

  • @78deathface
    @78deathface 2 года назад

    Those crystals at 2:36 sure are pretty

  • @markwoll
    @markwoll 2 года назад

    Wow, just wow!