Understanding Dose, Fractionation, & Toxicity

Radiation dose is a complicated concept, because it's not nearly as simple as the total dose prescribed. The dose per fraction matters a lot, the tissue that's being radiated matters a lot, and the total time over which the dose is delivered also matters a lot. How do we reconcile all of these when it comes to understanding radiation dose, fractionation, and how that plays into normal tissue toxicity? In this talk, we try to break down how to think about radiation dose, fractionation, and how they play into normal tissue toxicity.
This presentation is created purely for educational purposes and does NOT constitute medical advice. If there are any errors or questions/concerns, we welcome comments and discussion!

[@2minutesrevisionmbbs401]

Thankyou mam this is soo helpful please make more videos like this 🙏 I'm doing radiation oncology from India

[@ArshmeenKaur]

In the summary slide i think there's a typo. Early reacting tissues have high alpa/beta and vice versa right?

[@Rad_Onc_Talks]

Thank you for noticing! Yes, that is a typo. Early-responding tissues (e.g., tumor) have high alpha/beta ratio and late-responding tissues (e.g., spinal cord) have low alpha/beta ratio. There is another error earlier on as well - "biologic equivalent dose" should actually be "biologic effective dose."

[@ArshmeenKaur]

@@Rad_Onc_Talks thanks for replying, excellent videos btw!