CRISPR System and CRISPR CAS9 Technique, The full principle (Part 1)

This video is a full explanation of the CRISPR system and the utilization of this system in gene engineering (Part 1).
The link of part 2:
• CRISPR CAS9 Gene Editi...

[@merttantari5473]

finally someone who explains this topic very clear and also detailed enough :) thank you , it was really helpful !!

[@priyamvadam4928]

really good. much more detailed than most videos available on the same topic.thanks.

[@lembuhota]

True

[@anushabs6599]

Exactly!!

[@lethaltrix316]

GOAT CRISPR Video

[@chemistrymattersgetit4161]

Very well done, great for both undergraduates and the more advanced. I found especially useful the way you distinguished between the 3 different systems, which is often not clear to those who are first learning about the system.

[@aaryashashi173]

This is one of the best detailed video on CRISPR i have seen in RUclips

[@chuti_vanila]

Thanks​ you​ so much, you​ explained clearly for​ this​ topic.​

[@mirzamudassir3937]

Thank you so much for this vedio I exactly understand how crispr work

[@eddiewampande5107]

This was fantastic, i can now apply the technique of crispr in my research

[@RealJulWhite]

Great Video! Have suggested the channel to my professor so he can recommend throughout the next years

[@VijaySingh-tg1be]

So far the best video on CRISPR basics. Easy to understand in layman's langauge...

[@ahmedmohamed-iu2fj]

Wow I’ve watched this couple times and u explained it very well. Thank you

[@IbuWdesta]

Really nice presentation, much more detailed. Wait for your next presentations

[@OrlandoRodriguezHK]

Many thanks for the video, it is very clear. Well done.

[@lucasalopez-jirau4714]

Thank you!!! Excellent for undergrads having trouble with the primary sources; it really helped me. * thumbs up *

[@RomanKenzie]

Amazing, thank you for taking the time to make this- really helpful!

[@nataliyamelnyk5904]

Thank you for the great explanation of the great system work!

[@nika_cm]

thank you, this was very clear and easy to understand, it helped me out a lot!

[@animeshhb]

so nicely explained ! A big thanyou for making me understand the whole process in a easy way !

[@lukengai4956]

tysm this was what i was looking for for so long ;-;

[@kathleenranihagen9256]

This was great! Now I finally understand. Thank you!

[@biomedicalandbiologicalsci4989]

you are welcome :)

[@danielholley2495]

Excellent video. Thank you so much!

[@rababeleit5317]

Wonderful explanation!!!

[@NookKana]

Thank you so much. This is so helpful. Great video and great explanation :) I can understand about CRISPR system better in just twenty minutes. Thank you

[@biomedicalandbiologicalsci4989]

Thank you for your comment :)

[@inshaishrat4371]

The best of all videos. Thank you 💕

[@DhobyVic]

Thank you for a very helpful explanation. It's not an easy topic and I will need to watch the video again a few times for it all to sink in but, essentially, and for the first time, I feel I do understand.

[@StepsHardcore]

This is so generous and clear. Thank you so much.

[@sumantamohapatra6727]

Literally very informative mam

[@ximenaze8242]

Great video! Thanks for sharing

[@farhanabbas2728]

Very helpful video about CRISPR.... Thanks alot for guiding

[@maximilianfischer9198]

Great video, just a minor suggestion: I would give a short general overview (basically the summary that you give at the end of the video) of what the system does and the goal at the beginning of the video and then go in detail.

[@utsavvaghasiya]

very detailed and easy to understand this complicated mess. thank you

[@mdshahidulislam6805]

Yes, it was very good to understand easily. Thanx.

[@kianakhz4558]

Very helpful.Thank you

[@debashreedas9897]

Well explained. It helped me a lot! Thank you so much!

[@desuranus7349]

At 9:15, cas6e/cas6f cut at the junction of ssRNA and dsRNA. The graph is not correct. It should stop at the end of hairpin loop. But this is minor detail. Many thanks for the videos. This is the only CRISPR video in English I can find on youtube that teaches type I, II, and III. Thanks!

[@dimitragennimata89]

Excellent presentation. Ideal as an educational resource, for explaining how the system works in bacteria. Very well done, indeed.

[@biomedicalandbiologicalsci4989]

Thank you for the nice review ... stay tuned :)

[@AnkitKumar-nh5io]

Biomedical and Biological Sciences very good explanation

[@jacquelinelabovitz4613]

fabulous explanation. thank you

[@dennisalego6548]

Thanks so much, exactly what I have been looking for 🙏

[@giuliarossetti197]

Thank you very much! It saved my lifeeeee! :D

[@martingitonga5436]

Wow, very help basics! Thank you

[@CropScienceyt]

Detail information in simple language with presentation

[@BeUWinteer]

Thank for sharing this video. It very greatful.

[@70194tanner]

At 8:12 you refer to the lower strand as the coding strand. I believe that this strand is actually the template strand because the newly synthesized strand would have the same sequence as the top strand. That would make the top strand the coding strand and the bottom strand the template strand.

[@mohinitalwar2888]

You are right the coding strand is actually the Non template strand as it contains the SAME nucleotides as that of mRNA while the template strand contains the COMPLEMENTARY nucleotides

[@fagusformigordusfagordumfl1798]

yeah right

[@LKVPAWAR_ycmou]

Exactly right.. bottom strand is template ..

[@LKVPAWAR_ycmou]

@@mohinitalwar2888 I didn't got the Non template strand concept please explain what u said in didn't understand it please

[@mohinitalwar2888]

@@LKVPAWAR_ycmou as you know there are two strands, template and non template. And because template strand has the complimentary sequences with that of mRNA (the complementary rule) that means the another DNA strand (non template strand)has the same sequence as that of the mRNA (except T in place of U) that's it is called as conding sequence as it has THE SAME CODES as that of mRNA.

[@qaisarshakoor09]

Thank you very much for the explaination

[@garyraab9132]

Informative content, with simple and useful animation.
Having produced hundreds of science videos and animations, some simple suggestions for the sound track.
First, write out a clear concise script.
Do a second edit on the script.
When recording the script, speak each line clearly, leaving a long pause in between each comment.
Avoid ummms and awes!
With audio editing software it’s easy to adjust the length of the audio to match the animation.
With the audio editing software, it’s easy to recognize and find, ummms and awe waveforms and replace audio distractions with silence.

[@carloseduardoferreirapache9428]

Very well explained, thanks!

[@srishtisharma3200]

Amazing video !! You win it !!!

[@harunkimathi8515]

thank you! very clear

[@gcris9927]

Thank you, very useful!

[@juandavidolayacelis2626]

Great video. Thanks!

[@bdhome2010]

thank you. it was an awesome video.

[@medineadin4700]

Thanks, it is a very good explanation

[@edthoreum7625]

4:09,3 steps
1-spacer acquisition,4:21
2-crRNA processing,7:30
3-interference,10:55

[@ryanhimawanwibowo6014]

Thank you so much!! well explained :)

[@sydfarag3345]

Great work, thanks

[@tukombemuleya9689]

well well. this was so clear ma'am. i understand it well

[@IshitaJain10]

A great help...thanks

[@lembuhota]

So simply explained with details... And also very simple and nice animation.... Great work... Keep explaining topics like this.... Your video helped me a lot... Thank you 😊😊👏👏

[@vaishnavibhike1586]

Well Explained!

[@ankushbajaj5764]

👏👏👏GREAT JOB. pls keep uploading videos on ur channel. 🤗🤞

[@ahmedalfahad3866]

Thanks very useful

[@maiaralarissa8805]

Thank you very much! Excellente explanation!

[@biomedicalandbiologicalsci4989]

Welcome :)

[@suvethas1851]

Very well explained 👌

[@arvindgond4149]

Very well explain
I think 1st (this video) is essential to create base to understand CRISPR .
Thank you for breakdown it and explain it in the simplest way 🙂

[@v.ariabod5488]

excellent and very useful video and explanation

[@lucho0849]

very good explanation am able to better understand the processes involved

[@_MercyStephen_]

You made it so well

[@maomaotan8270]

YOU ARE AMAZING!

[@arkveth6921]

I believe that at 10:43 you wanted to say Cas6 homolog (as written in diagram) instead of Cas9.

[@oui1205]

Great Job, you helped me a lot

[@biomedicalandbiologicalsci4989]

This is my target :) thank you

[@amonoracheal9118]

impressive explanation:)

[@lujainalnemr8983]

Thank you so much you are the best

[@Wathiq199317]

thank you it was very clear and easy

[@sandeepshinde8806]

Great attempt 👍

[@mohammedtolba9886]

Great .. really Great

[@hemastandard7649]

Great video I understood really nicely and loved the accent, very understandable (perhaps you can make an updated video on the subject).

[@Quotila0]

Loveeeedddd it. Very detailed.

[@OzgeSonmezler]

Hi! Thx for the video, helps a lot. Is there any place i could find it as pdf or ppt?

[@sumerarajper8294]

Very informative

[@zph1806]

Thank you so much for your very nice explanation it wa really very helpful ❤️

[@dikshashreedevi4568]

very usefull...plz make more videos.

[@enerandmackon761]

great job

[@MatheusLimaMatias]

Well done

[@anshumathur7585]

Thanku mam to share this video Its good enough to understand the mechanism of crispr bt i hv a query regaring this as u told about crispr mechanism to bacteria protect from viral infection as immunity, bt there is also the lytic or lysogeny cycle where they protect from adverse conditions what about ds?

[@hiraateeq3186]

Best explanation very helpful

[@biomedicalandbiologicalsci4989]

Thank you for the nice comment :)

[@cagaditamiaditas6280]

Fuck you

[@wdyafw]

This video explanation is very helpful especially for a beginner like me. Could you please also explain how CRISPR/Cas9 disappear from the genome of an organism? Thanks.

[@rumasarkar1382]

Thank you very much...

[@Shadowdarknessone]

a really great video. I just dont understand one thing. where did you know where to cut. And how did crispr knew where its needs to cut and replace the dna/rna or modifie the dna/rna. As far as i understand it crispr splits the rna/dna up but where did know what you need to pick.

[@bioinformaticforall]

very helpful tnx

[@md.ridwanahmed1769]

Do you have this crispr 2 video as an article???

[@toyito1]

Thanks!!!!!

[@familieaa1968]

شكرا جزيلا

[@bakeral-shara4530]

Nice go ahead

[@bharathreddy9337]

thank y very much and I like your video presentations. have y made any videos jumping genes(transposons)?

[@biomedicalandbiologicalsci4989]

Thank you for your comment, I will try to do it :)

[@sarmadElhassan]

Very helpful, however PAM position is on the non target strand 3’ to the protospacer

[@ahmedshadulla7463]

🔥🔥🔥

[@andreagoh6198]

thank u for teaching me what my teacher did not teach but wants to test T.T

[@majdr.sweidan4606]

Hello thank you for the interesting vedio, i really enjoyed it, but I have one question, Im smolecular biology and genetics student and I have studied that the coding strand is the strand that is identical to mRNA " thymine instead of uracil" but in the vedio you said the the coding strand is the strand that was transcribed into mRNA , can you explain this to me ?
Thank you

[@rikkigupta9546]

thanks alot for easy explanations could u pls send me its refrences

[@christianadipratama2310]

Does it always be 5' to 3' that became the template DNA? I was taught that 3' to 5' is the one that will undergoing transcription.