Thank you for taking the time to make the animation and explaining the concepts. I couldn't understand the graph and didn't know how to interpret it until I watch your video. Keep up the good work!!!!
Fantastic video! I was just wondering if the net ultrafiltrate illustration at the end should actually cover even smaller highlighted area because there's a gap between the bottom line of each P_bs and pi_bs. Rather technical and not rly important (plus nothing's wrong with the calculation and equation) but just wanna make sure I get it correctly. That aside, thanks for making the video. Very succinct and helpful.
Hi, interesting observation. It's possible that it could be a little smaller in the illustration since we only approximated the calculation in the animation. Hopefully, that wasn't confusing. Thanks for the comments.
Hi playitback8623, Good catch, you are correct, hydrostatic pressure decreases slightly as blood moves into and out of the glomerular capillary due to filtration.
Yes. In fact, this can happen when the filtration fraction increases from the typical 20% to near the maximal of 40%. This is referred to as the paradoxical effect. Does that help?
@@LanceMillerPhD Unfortunateley, I do not know about this effect. However, now I know how this is called and I will do some research. Thus, this helps me. Thank you for your answers and videos! Greetings from austria :)
You are welcome. You are not the first ask this type of question. In fact, it's a challenging topic to teach and it's often tested on the USMLE Step 1 exam. You've motived me to make a short video to explain the paradoxical effect. I'll be posting it by the end of the week. Cheers.
When there are proteins in a fluid, they like to keep the water for themselves and this happens in all the vessels. in this case, glomerular capillaries proteins are preventing the water from escaping towards Bowman's Capsule. AKA they "oppose" filtration.
Now this is a guy that really deserves the Doctor title. Hats off
Absolutely perfect description with this animation. I can't begin to tell you how much this has help me with that concept
Thank you for taking the time to make the animation and explaining the concepts.
I couldn't understand the graph and didn't know how to interpret it until I watch your video.
Keep up the good work!!!!
Thank you so much this is a very straightforward and clear explanation
amazing animation and explanation..
.keep up the good work
The explanation is marvelous. I liked it
Best explanation of this topic I was struggling with it thank you
Perfect explanation.Thankkkkkss
This is perfect explanation, thank you very much
Glad it was helpful!
Incredible!
Fantastic video! I was just wondering if the net ultrafiltrate illustration at the end should actually cover even smaller highlighted area because there's a gap between the bottom line of each P_bs and pi_bs. Rather technical and not rly important (plus nothing's wrong with the calculation and equation) but just wanna make sure I get it correctly. That aside, thanks for making the video. Very succinct and helpful.
Hi, interesting observation. It's possible that it could be a little smaller in the illustration since we only approximated the calculation in the animation. Hopefully, that wasn't confusing. Thanks for the comments.
Thank you so much
We appreciate your effort!
Thank you so much doctor! you made it very easy
Outstanding! 👏🏻
You’re the best thank u
Thank you so much sir
Beautiful video :)
This is good. Thanks!!
how can hydrostatic pressure stay the same if there is so much loss of volume that the colloidosmotic pressure increases by about 15 mmHg?
Hi playitback8623, Good catch, you are correct, hydrostatic pressure decreases slightly as blood moves into and out of the glomerular capillary due to filtration.
@@LanceMillerPhD Hi, can a slight decrease really account for such an increase in colloidosmotic pressure or are there other factors involved?
Yes. In fact, this can happen when the filtration fraction increases from the typical 20% to near the maximal of 40%. This is referred to as the paradoxical effect. Does that help?
@@LanceMillerPhD Unfortunateley, I do not know about this effect. However, now I know how this is called and I will do some research. Thus, this helps me. Thank you for your answers and videos! Greetings from austria :)
You are welcome. You are not the first ask this type of question. In fact, it's a challenging topic to teach and it's often tested on the USMLE Step 1 exam. You've motived me to make a short video to explain the paradoxical effect. I'll be posting it by the end of the week. Cheers.
Why does the glomerular capillary Colloidal osmotic pressure oppose the formation of filtrate?
I have the same question
When there are proteins in a fluid, they like to keep the water for themselves and this happens in all the vessels. in this case, glomerular capillaries proteins are preventing the water from escaping towards Bowman's Capsule. AKA they "oppose" filtration.
@@doctord7171 thank you replying , it's been so long I don't remember shit 😭
@@shanthala1345Yeah I bet you are graduated now haha
Bless you.
Thnku sir😇😇😇
What is Filtation
Your too deep bro
Great job
wonderful thank you
Nice
Speactular... 👍
Thanks.
🙏❤️❤️❤️❤️❤️ than you
Speactular... 👍
Thanks.