Melanoma and BRAF (pronounced “Be-Raf”)

In this video, Melissa Wilson, MPAS, PA-C, Melanoma Lead at UPMC Cancer Center and AIM at Melanoma's Ask A Medical Expert, explains what BRAF in melanoma is, when is BRAF tested for melanoma?What does a positive BRAF test mean? Is it better to have BRAF positive or negative?
How is BRAF mutation detected?
The information in this video is correct as of 26 August 2022.
For more information about melanoma or to ask Melissa a question, visit: www.aimatmelanoma.org/
Twitter: / aimatmelanoma
Facebook: / aimatmelanoma
Instagram: / aimatmelanoma

[@bobjensen7136]

Thanks for your videos and sharing your knowledge with us. You are very informative and I will like to hear more from you. Sincerely Bob

[@jennistevenson796]

My son is recently diagnosed stage 4. He is B-Raf wild and has been told targeted therapy is not an option for him. He lives in the UK. Do you know of any target therapy for B-Raf wild. He is starting immunotherapy in a few weeks , combination nuovo-ipi. He has had a brain tumour removed and has lung nodules and liver mets.

[@Tammy-mj2rw]

🙏

[@FromTheClinicToTheLivingroom]

These are our partners in the UK: www.melanomauk.org.uk/
I would reach out them with your questions as some treatments are different.

[@noorsharabi5399]

Braf isnt in normal cells??

[@FromTheClinicToTheLivingroom]

Yes, all cells in the body have the BRAF gene. The BRAF gene is located on chromosome seven and encodes the B-Raf protein, which regulates cell growth, differentiation, and proliferation. When the BRAF gene is working properly, it's an important part of how cells function. However, a faulty BRAF gene, also known as a mutation, can work against the body and allow some cancers to grow- melanoma is the most common cancer where the BRAF mutations are found.

[@noorsharabi5399]

@@FromTheClinicToTheLivingroom thank you so much