New Study Shows Collagen Doesn’t Work? Controversial!
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- Опубликовано: 2 сен 2023
- A new collagen study has shown no effect for connective tissue protein synthesis, and has gone viral on social media. Before throwing out the collagen peptide supplements, we need to figure out how strong the previous evidence is, and how this new study fits in to the overall picture.
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Here are the links to the research papers referenced in the video:
pubmed.ncbi.nlm.nih.gov/37202878
www.sciencedirect.com/science...
pubmed.ncbi.nlm.nih.gov/23949...
pubmed.ncbi.nlm.nih.gov/26362...
pubmed.ncbi.nlm.nih.gov/32436...
pubmed.ncbi.nlm.nih.gov/33774...
pubmed.ncbi.nlm.nih.gov/36516...
pubmed.ncbi.nlm.nih.gov/36916504
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/31859...
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#Collagen #Health #SkinCare
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What do you think about the conclusion at the end?
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I do the collagen peptides 20 grams w 5 g of leucine and 5 g of creatine and am pleased w results
I think that like a lot of these trends like a caveman seeing an automobile. Cave man is smart enough to see it runs on petrol so thinks washing the car in petrol and putting petrol in every portal into the car will make it run faster.
I agree with your conclusion, that one study only talks about collagen protein, not peptides. And there’s a lot of good evidence like the one you’ve shown on this video collagen peptides are indeed beneficial.
I'll continue with my daily shake at lunch, 20grams of peptides, cacao with phenols, 5g maca root with 5g of pea protein included and green coffee bean, and 3 teaspoons of triple fiber (acacia, psyllium, and inulin). I mix this with banana milk.
@@agripermawhy maca ? what benefit does it give ? thank you
Started collagen over 2 years ago because of pain in my hips which is hell when you’re a side sleeper. Six weeks on the pain had completely disappeared! Call it whatever you want but that is just enough for me, a sixty year old, to keep investing in collagen peptides for the rest of my life.
Hi! What doses do you take? And which colagen suplement in particular?
Good customer
the placebo effect is powerful
Collagen from bone broth has kept what was increasingly disabling arthritis in remission for me for years now, & repaired hair & nail problems caused by a previously so-called 'healthy' excessively plant based diet.
@@jorgelizaso978this one they showed in the video with the 🐮 baby blue on the container . Is a good one!! It does help.✨there’s another one you can trust also from “ ANA MARIA LA JUSTICIA “.. Ashe has her own brand. She is from Spain, and has many years giving conferences talking about this collagen supplement as well as other supplements,for example “ magnesium “ deficiency… e. t.c. A trusting brand.✨
Taking Collagen has had a clear and obvious effect on my skin. For me, it absolutely improved my skin. I just add a couple scoops in my coffee every day and my skin is very smooth and young looking. I'm 57 and so the "before and after" is not subtle at all. I can recommend to anyone and everyone.
I had a similar experience my self
Which brand do u take?
@@King311___Ancient Nutrition for me. I’m convinced it has many benefits - gut, skin, hair…
it's true!
I take Sports Research brand. @@King311___
I had knee pain that came on and off for decades. Brought it to different doctors and specialists and none of them were able to figure it out or solve it. The only thing that gave me relief was regular collagen supplementation. In just under a year my knee pain gradually disappeared. Now I’m pain free.
Its called placebo.
Could be
Similar experience here... I started having knee pain in my right knee two years ago from doing so many hours of driving during the summer making Uber eats delivieries for extra cash. I stopped driving long hours, and my knee felt better, but it would still agrivate me enough that I'd just been taking ibuprofen every morning since then. Back in June, I started taking a Collagen Powder in my morning ice coffee (it has verisol, fortigel, and fortibone in it) for vanity reasons, I wanted nicer skin... I never thought about it helping my knee, but by the end of July, i realized that my knee wasn't hurting me anymore, and i finally stopped taking ibuprofen after a year. Did my knee just need two years of healing and taking ibuprofen, or did the collagen powder finally help it heal all the way? I believe in the collagen powder.
You probably got the supplement with the ideal peptides for joint health. It kind of confirms Dr. Stanfield's final remarks. Congrats.
@@Nobody-Nowhereok controversial but if it worked for them let them (even if it was just the placebo), if they stop taking it the effect will go away
Dr. Stanfield, Thank you so very much for your diligence in researching and comparing so many different studies that, for the layman, can be very confusing and/or misleading. I am a healthy, active 79 year old woman who believes in holistic health and in taking supplements. Being on a fixed income I must pick and choose wisely which of the reverse aging supplements I can afford. I trust your expertise and your judgment and truly appreciate you sharing your own regimen with your followers❣️🐅
Aaawww what a nice comment. All the best to you lady!
This latest study reminds me of the fitness industry, specifically single studies on muscle hypertrophy that start with the wrong question or faulty assumptions and then produce results that are generalized. For example, such and such exercise doesn't protect you from injury, says this new study. Only, nobody used this exercise because they think it protects them from injury. Yet, fitness influencers are quick to say, don't do this exercise, according to the new study. Your results are only as useful as the questions you ask.
Isn't this with about 90% of the studies you hear about? Once you've looked deep into a topic, most questions asked by studies make no sense (to you). They may make sense to somebody, though, from a different perspective. Like Vitamin D supplementation studies where the Vit D serum level is never measured (yes, these studies exist).
Your thought on 'starting with the wrong question' is pervasive in so many scientific studies. I will also add the fault of not addressing confounding factors is also a massive issue.
That would be injury from exercise, so the question was does the supplement help you heal better and not get injured as much working out, which are hypertrophy questions.
And the Aussieker 2023 study looked at a small group, one day, one dose. Meh.
@@TwdlD there are no wrong questions, only questions that are relevant or irrelevant to you. It's up to the person reading the study to decide whether it applies to them.
Just started collagen not too long ago. Was never a believer in collagen. I can already see a difference in my face complexion looking better, and my nails growing faster. I’m definitely not protein deficient either. The reason I did not use collagen in the past was because I consumed well enough protein. But after listening to so many anecdotes about collagen use, decided to give collagen a try, and I’m not going back.
Which brand do u take?
Which brand are you taking please? Thank you.
@@Lolipop59 which brand r u taking
@@Lolipop59 Lake Avenue collagen peptides, by IHerb. The cheapest you’ll find, but no different quality than the expensive brands.
@@King311___ Lake Avenue collagen peptides, by IHerb. The cheapest you’ll find, but no different quality than the expensive brands.
Back in 2020, I started a job that required a lot of walking (at least 20 kilometres, 5 days a week) and it wasn't long before I started feeling a tingling pain in my knees and my ankles.
Back then, I had no clue about collagen. All I knew was any issues in or around bones means taking calcium, D3, and K2. I found out about collagen through online forums and decided to give it a shot. What it did for my knees and my ankles was no short of astonishing. It started to reduce the pain and eventually made it vanish altogether while I continued to do the same job with the same frequency AND continued by intense cardio routine at least 6 days a week. This is not an isolated case as even my colleagues in that job had the same experience when they started supplementing with collagen peptides. I personally used a blend of collagen peptides and turmeric in the beginning.
To this day, I take bovine collagen peptides so much religiously that my protein shake isn't complete if it doesn't have 10 grams of collagen peptides in it.
(For anyone concerned about the 6 days a week cardio bit, it has been replaced with resistance training now 😉)
Im also adding 10g Collagen peptides into my smoothies but also taking Tumeric and 1000mg DHA fishoil daily, so im not sure what exactly is keeping my bones and joints pain free but it works. Also taking lots of other supplements but im pretty confident it's either one or combination of above 🌴
Thank you both for your comments. 💙🙏
I eat only 3g collagen per day 😢
@@indiankid8601 i doubt 3 grams will do anything, you need between 10g and 30g per day. I only take 10g but I also take 30g whey protein amino acids, big dose fishoil and eat animal fats and skin, every day.
@@indiankid8601why ?
As someone who struggles with very dry skin and psoriasis patches, I definitely take collagen peptides to help with my skin specifically and I'm satisfied enough with the results that I've been taking it consistently for 3 years now.
Living with dry, cracked skin is torture, so even 10-15% improvement in skin hydration is enough for me 😂
Which brand are you taking please? Thank you
@@Lolipop59I'm taking FINE Japan Collagen, but I switch it up depending on what I can get my hands on because I just follow the criteria of 1) at least 5000mg collagen peptides per serving and 2) Marine collagen with no porcine elements (because of religious reasons).
Check your diet. I’ve cured my eczema with fasting.
Does collagen improve skin quality?
@mirasingh7428 not sure about skin quality in general, but if you're like me and have extremely dry skin to the point where there is tightness and cracking, you will feel a difference.
Very good to know ! I have been taking collagen peptides recently. I noticed it made my skin so much more firm!
That study was bad science!
They replaced a reasonable dose of a good protein for protein synthesis with an equal dose of collagen, which is not a complete protein, and not very bioavailable.
My guess is those given the collagen supplement were protein starved!
Did they even used hydrolyzed collagen, which is much better bioavailable?
The correct way to uses collagen is to add it to your ordinary protein, and not as a replacement. And utilize a hydrolized form.
Just add about 10% of your proten as hydrolized collagen, or about 12 g.
If the researcher had done that, they would have gotten results. Just like you do if you do it like that!
OP like click bait titles cause he’s a failing Dr. From what I can tell..
@@taccntb4345I am starting to think this. He seems very plant based biased to me.
@@carnivoroussarah thinks a guy who advocates collagen supplementation is "plant biased"😂
I think collagen peptides have made greater improvements on my skin more than any creams or lotions I have used on my face. Within 2 wks I already started to see the difference.
What results u noticed?
Please reply
@@mirasingh7428 The skin has become more plump and tight.
I’m in my 70s, a classical guitarist who suffered with extremely thin, peeling nails and tried everything for years; finally started adding 2-4 tablespoons of collagen in a daily protein shake; now have strong nails, better skin and hair, too. Also noticed joint pain disappeared. Collagen works if taken regularly.
Thank you for your input, I found his comment that most people take collagen peptides for their skin so therefore no discussion of joints to be rather dismissive even if that can be proved because many people are interested in the potential benefits for joints. I hope it will be addressed in future discussion as a lack of joint health as one ages is far more critical to a healthy active life than an 8% improvement in skin moisture or elasticity which may be addressed through other means.
I'm also a guitarist that suffers from dupytrens contracture, which is when collagen attacks your fingers. I'm wondering if taking collagen supplements will worsen my condition
@@paulfreedman8121 Interesting question. In theory, it might. dupytrens contracture appears to have a genetic component. So you'd want to find a top notch ND or functional/regenerative MD who can recommend epigenetic treatments. Self Decode may give you some clues.
Do you take collagen or collagen peptides?
Fantastic video, thank you! I’ve seen other doctors on RUclips jump on the collagen supplements don’t work because of that one study, when that study only talks about collagen “protein”, not peptides.
Great work, as always.
Very intersting, thanks for helping us keep up with the research :)
I personally have been taking collagen daily from a brand called Renewed Health. Their collagen also contains vitamin C, zinc, silica, and biotin for the collagen boosting properties. For me, I really noticed an improvement in gut health and skin health almost immediately. Again probably due to the combo of collagen with vitamin C, zinc, and silica. Really incredible stuff!
Combo of placebo and vitamin C.
@@Nobody-Nowhere Collagen is well known for improving gut health, so it might not be placebo. I do actually consider collagen to be a relatively 'poor' quality protein, but it certainly works for some people. I've never used a collagen supplement myself. Personally, I eat a mostly meat and eggs (hyper-carnivore) and that includes gristle, sinew, tendons, skin, anything that is reasonably edible, which is normally everything.
@@Nobody-Nowhereyou don’t have any evidence to support your remark.
@@Nobody-Nowhere Yep.
@@Nobody-Nowherewell all of modern medicine like vaxs and stuff is all placebo
Thank you Brad! As usual, top notch professional non-bias constructive approach.
I know how it has helped me. I will never not take it! Thank you so much for all your work!
Now we need more studies finding out what each individual type of Collagen do.
Exactly
Type 1 = all for fun
Type 2 = looking for you
Type 3 = all about the wee
Type 4 = wants more albacore
And more on organs, not just skin. Looking young isn't enough.
We have them. Lots. They just conveniently ignore them because they don't fit the plant based agenda since many amino acids are found only in animal products and the false consensus is that animal protein is bad.
@@MochaZilla 😂
Adding to the chorus of anecdotal evidence, collagen has eliminated both my shoulder and knee pain from injuries that left lingering pain for years. Now that I think about it, my skin is better too. I don’t believe it’s a placebo effect, given the severity of my past pain, so I’ll be taking it for life.
Dr Stanfield, so many channel owners could take lessons from you. Your videos are always well organized, well presented, and easy to follow. You always manage to provide a significant amount of detail in a surprisingly short amount of time. Keep up the great work!
Interesting. Thanks for pointing that out
Thanks for the clarification! 😘
All I can say I definitely see a big difference since I’ve been taking collagen every morning in my tea. My skin elasticity is great and improved I stopped itching on my forearms neck and face. I no longer get heartburn after anything I eat versus any and everything I ate felt like it would come back up (and many times it did come back up) those days are gone.
My 80 year old parents started taking 1 scoop of vital proteins unflavored in their morning tea and said their joint pain and stiffness is gone, the only study I need.
Hi.hooe you don't mind if I ask.what vital proteins unflavored your parents taking?
Hmmm…interesting. I have been taking Ancient Nutrition collagen peptides and my nails were/are growing like crazy. I don’t really have any joint pain or skin issues. Anyway, I once tried the Vital Proteins brand and my accelerated nail growth stopped. Your parents may want to consider Ancient Nutrition brand…
There was a mri study years ago which showed the improvement in cartiledge in bones, the skin has been well shown and it has been found in the tendons a long time ago when labelled compounds were used. There seems to be an inherent flaw in the methodology.
Excellent evaluation as usual, Dr Stanfield. Thanks!
The molecular weight, type (1,2,3), formulation (e.g. UC-ii), dosage etc have a huge effect.
But perhaps also, what other ingredients were in the supplements? Sugar could reduce the effect.
I also wonder if timing in the day makes a difference too.
So many clinical studies show benefits on skin, joints and even gut lining.
Would love to see a review of hydrolysed collagen vs vegan collagen builders
Thank you Dr Brad, much appreciate this video. Glad of your approach.
Your studies are good at disapproving every supplement, nice work, keep it up
Good video, topic was covered honestly and clearly... Personally I take both whey and collegen peptides.. not for muscle repair, but because these represent some of the best sources of cysteine and glycine respectively... And if taken at the right ratios, they cover most ( but not all) of your essential and conditionally essential amino acids...
Could you share information about ratios, and how to get them right ?
@@freshstrt3140 absolutely... As a general rule, when considering the 9 essential amino acids, it's best to keep intakes to multiples of the adequate intakes for each one. As in if you take twice the AI for histidine, you should also take twice the AI for the other essential amino acids as well. When it comes to the conditionally essential amino acids, that's a bit more of an open question as this is an area of ongoing research. However when it comes to the amino acids cysteine and glycine, there is sufficient evidence to suggest that glycine should be taken in excess of cysteine. A 3:1 glycine to cysteine ratio seems to be likely to be close to optimal. There are multiple reasons for this, partly due to how the body uses more glycine than cysteine in a number of processes, and partly because when glycine availability is too low to sustain normal rates of glutathione synthesis, the consequent rise in tissue levels of gamma-glutamylcysteine results in increased conversion of this compound to 5-L-oxoproline that is then excreted in the urine, making glycine the the limiting factor in the synthesis of glutathione, even in the presence of excess cysteine....
As for how to achieve the correct ratios.. luckily, this is thankfully quite easy to achieve due to the unique properties of whey and collagen peptides... Although there is some variation between vendors, as a general rule, 30gr of whey protein concentrate and 5grams of collagen peptides will provide a 3:1 ratio of glycine to cysteine, and the correct ratios of all 9 essential amino acids...
Hope that helps.
@@michaelransom5841 What research are you looking at for cysteine to glycine ratios?
Thank you for keeping us up to date on the latest research findings! Helpful for me to make informed decisions.
would love to know more about supplementing collegen peptides vs gelatin as amino acid supplements
Thank you for all your expertise that you share.
Before I started taking collagen I never had to cut my hair. Hadn’t cut it for years! Now I have to cut it at least every 6 months. It grows so fast.
Same here. It helps!
male 47, I use collagen in an effort to preserve muscle and connective tissue and articulation health. My current course is 100mg vitamin C, 12g glycin, 20g collagen hydrolysate powder from beef. I do not count collagen in the protein consumed. From january to July I lost 14kg and the withings says I lost only one kg of muscle (so I lost mostly fat in the abdomen, the belt shrunk). The main strategy is low sugar flour ethanol, and more protein and fats, and do zone 2 walking fasted. Feeling is amazing, mood is stable happy, cognition and productivity at work are much improved. As a side effect I can see in the mirror face is also improving. The collagen powder taste great in salads, eggs, mixed in minced meat, or in sauces. I don't care if it works or not, I feel so great that I don't want to change anything!
Perfect analysis as always…
Dr. Brad, great as always. In the late 70’s and early 80’s I was in contact with Dr. Alibi at the Pittsburg burn center. He had worked with a number of peptides to accelerate wound healing. He indicated to me that certain dipeptides were much more effective than others at accelerating healing. I believe his pick at the time was leu-ala or gly-leu. So I think your hunch was correct about specificity. About that time, George Blackburn (who came under fire later for some of his publications) published a book called, “Amino Acids”, wherein he surveyed many of the studies to date that elucidated the mechanisms of peptide absorption, metabolic fate and effects. For example, Tyrosine might be conditionally limiting in athletes under certain athletic and dietary stresses. The information at the time supported the statement that, as a free amino acid, tyrosine is so slowly absorbed from the gut that it can still be identified in mucosa 4 hours later! But as a dipeptide with glycine it is absorbed in minutes. I think there is still a great deal of work to be done here, because good science is so hard. Our early conclusions may be invalid or, at least, insufficiently understood. But I think information has been available for more than 40 years that supports the conclusion that peptides can make a difference over intact proteins and that the composition of the peptides matters. Best to you!
Great video Brad! "Enough protein" seems to provide 2g of glycine per day. I was sold on collagen with the microscope pictures, before and after. Small improvements are felt on such a huge organ filled with sensation.
@@PaulB_864u millionaire, I luv 🥩 but too expensive 😢
@@PaulB_864according to Google skirt has more than 25g per each 100g
I started collagen several years ago. Didn't really think anything much about it - just started taking it and forgot about it. Well, after about 6 months (with no other change in my diet) - I was shocked at the following results. 1) my skin inflammation on back of elbows disappeared after 40 years; my skin elasticity returned like a 20 yr old (I'm now 70) - nothing short of miraculous; and my damaged left knee of 20 years seemed to heal itself - so much so that i could run high speed again on treadmill. None of those issues have returned, and it's been over five years since i first started taking it.
Awesome to hear your are feeling better. Thanks for sharing
love your site - never miss your videos and often watch them multiple times! thankyou @@DrBradStanfield
@tracyau9122 Impressive! Skin elasticity of a 20 year old being 70? Is that possible? Meaning no wrinkles after using it?
Please explain.
listen, I would pull my skin up on back of my hand and it wouldn't even drop back!! ! - that is how scary my skin was. After the collagen and for last 5 years, it literally bounces back like a 20 year old. I wish I could enclose a video to show you! LOL @@MarsX69
@tracyau9122 Would be helpful if you could share the name of the brand. thanks much! 🙏
Hey Doc, what about for tendon health and repair? Any studies on this?
Thank you for your analysis
It works, my skin is fuller and glossier. The downside for me is stomach or lower abdomen (right side) pain when taken continuously.
Kidney stone?
@@rickgauden nah, apparently most people have that reaction when taking it. This happens to me if I take it more than 3 days continuously, so I do it on and off.
I am into Immunology and immunotherapy research work in Asia.
There are many collagen supplements in the market and some may be marketing products of low quality and also having false claims. Its not easy to believe what these companies and manufacturers (big pharma) use in their supplements, not to mention the huge profit margins on these supplements making them extremely costly.
I strongly believe in the consumption of fresh whole foods rather than go for processed supplements.
Dr Stanfield, have you thought about emailing the authors of the study to ask about the kind of collagen used?
I do believe there are specific peptides that give benefits for the skin. I've tried many brands, both marine and bovine, everytime I go back to one specific brand of marine collagen peptides due to how good my skin looks.
Which brand please
@@kathleen9456 It's a no-name cheap brand in Norway. I get that since I live here. Right now I'm looking into other well known brands with marine collagen to see if I get the same effects. I can report back.
Is it available on amazon? Looking for a good marine one
Men vad heter märket då? Var köper du det?
I see & feel 2 things *only* when I take protein powder (with all of the collagen types) 1. Removes joint pain in my knees 2. My skin gets very soft and bumps on the back of my arms disappears - I think it does help some with anti aging
I agree! I started giving it to my husband and saw a big difference in his skin, and I've definitely seen improvement in my own skin too.
@@flashgordon6510 Excellent! It definitely does something. I wonder if maybe it was the brand of Collagen they used ? I noticed the most difference when I switched from just a Type 1 to all types of collagen. I just know what I experienced and still do. =)-
Thanks for sharing your experience
I started to double my collagen from 1000 to 2000 mg about 3 months ago after I viewed your video on supplements (also doubled omega 3)
Have not really noticed anything re skill but my knees have been brought back to functional👍(had 4 op on meniscus over the years two on each knee🙁)
I now can play pickleball for over 2hrs without out pain😊
(Usually play 2x a week )
Not sure why but I’m gonna continue with the collagen and omega😊
@@DrBradStanfield Thanks for your information! We all have to be open to info that comes out and adapt where we need to if it proves to be accurate =)
Collagen is proline + glycine, both of which are easily absorbed. And the collagen "peptides" are broken apart by protease and stomach acid into those two individual amino acids anyway.
idk why people keep buying expensive collagen when they can just buy those two aminos for much much cheaper (and increase the dose) Glycine tastes like sugar, and proline is kind of sweet too. I use them to sweeten my tea. To rejuvenate skin and joints, add hyaluronic acid to the regimen with the money you save.
Bone broth does it all and more!
Interesting… how much to take of each?
@@larryc1616 however bone broth is very high in histamine, so it can severely disagree with people with histamine sensitivity and mast cell disorders. Since histamine and mast cell disorders are relatively recent discoveries, many who have them are undiagnosed. Those of us with these issues do better with supplements - but not all collagen supplements have the same benefits, particularly skin vs. joint health. I take proline, glycine and hyaluronic acid, but that can be fairly costly too and it is less convenient than a single supplement. Haven’t yet cone across a supplement with proline, glycine and HA - does anyone know of one?
Very interesting.
Collagen contains way more amino acids than just those two...
Amazing video! Thank you so much for the review on the different studies; you're really asking the right critical questions here. I think I've seen enough from various Dr. study analysis to judge that, yes, it is worth taking a PEPTIDE supplement. I think there's really a breakdown in understanding from the "team Whey" group of why people are actually taking the peptide supplement.
Interest& helpful!
I do have a question to anyone who is taking collagen and saw improvements in their skin - what source of collagen do you use? Marine / bovine? What brand do you recommend? And if you were taking collagen from different sources and brands was there any noticeable difference? Thank you.
Following
Following
Vital collagen..
As usual, I’m pleased to see your in depth reviews of the studies to clarify the knee jerk reactions triggered by this release of a particular study.
I will continue my collagen too! ..my nails, hair ..knee pain almost gone. I recently had a MOHS surgery on my nose… 2 days later I went to the plastic surgeon to fix the big hole left and he was amazed at the tissue strength and ease of doing the reconstruction. I’m 75 and he says usually skin is paper thin.. which mine used to be 2 years ago before taking collagen. Now it is no longer dry and itchy. My legs actually glow. I started lifting weights last year and feel much stronger with no pain. The MOHS surgeon said I had beautiful skin! So… I can see no downside of continuing the collagen.
Now if they would invent a Time Machine to undo the sun exposure I did in my 20’s and 30’s! Paying the prince now! Use LOTS of sunscreen after you take your collagen. Now THAT will be a miracle combo!😍🥰❤️🩹
RX
I use both collagen & glycine (and more) skin seems better at 76 years young.
Love that you're taking care of yourself ! I wish you the best
Been on collagen for two months. Dudes are giving me compliments on my skin. Never in my life had this.
thanks brad
Unlikely, there are too many people including myself seeing an improvement. That said, I'm really more interested in the hope that it also does help with internal organs, since I'm rather into longevity, not just looking young.
Great Work!
No placebo control
@@EkilRevolution
Sure, taking it yourself is not a study with a control group. But if something isn't harmful and it's cheap, then I certainly won't stop taking it, just because the science about it's usefulness is undecided.
That said, I wrote this before watching the video, and the study claiming that it isn't useful has it's own flaws.
@@NoidoDev studies very often return incorrect results, my only point was that your experience wasnt placebo controlled. i take collagen as well because it is high in glycine and low in essential amino acids and methionine. i have no idea from my own experience the effects of collagen, speculating on stuff like this leads to delusion and living outside of reality.
Honestly as a protein supplement in conjunction with other nutrient dense protein sources, VP Collagen has a wonderful effect on my performance. Stamina and strength during strenuous heavy lifting and high speed interval sports / training. Also muscle contractions are smooth with quick recovery.
Is this a hidrolized collagen ? Thank you
@@Lolipop59 the Vital Proteins brand Collagen Peptides is hydrolyzed and from Grassfed -Pasture raised cows. Costco has on sale with significant discount presently. Some complain of minor headaches because it’s rapidly absorbed, but I defeat that effect with beetroot juice or other antioxidant blueberry smoothie. Start with lower dose than recommended find what works.
I use it for joint health in combination with glucosamine sulphate and cod liver oil.
I have reduced pain allowing me to squat weekly where before I was often in too much pain to continue my session past warmups.
I wish I had access to testing methods to see what actual changes are taking place inside my body with the supplements.
So I'm wondering, is there a universal scale of measurement for these tests or does each study choose? That could effect the percentages produced.
I have heard about this study just recently from another RUclips channel that I watch sometimes by Lane Norton, and even if it's true and that it doesn't help to grow tendons I am taking for the skin health mainly based on the information from this channel. However we have to admit that the mechanism of action is not clear .. so it makes sense to be skeptical. If everything turns into bunch of amino-acids in the stomach how it suppose to work differently? That's still unclear to me, or how the mentioned transporter suppose to work in that case.
Thanks for your comment. I agree that there are significant unknowns, as explained in the video. It's possible that there are specific peptides which offer the benefits from collagen peptide supplements
I take it and it stops the pain in my knees! I think people who say it don't work have ulterior motives. .. I don't need a study to tell me that, I know that it works from direct experience that can't be argued.
@@bonanzatimeOMG, same here. After one week, my hair and nails grew faster with Vital Protein but I'm too lazy to take it because of the clump and hate using it in hot beverages because it changes the taste and smell of it. I bought the tasteless one but I need motivation to use it. I wish Vital Protein could offer liquid collagen.
It doesn't matter if we do or don't know how it works, if it still works. It would be great if we knew how it works, but if the evidence shows that it works, then we follow the evidence.
@@cheekymonkeygirl3378adding lemon juice makes easily drinkable for me.
Very good video.
You can find any study to say anything that you want it to say! I have used them for years and they are working for me! That’s all the study I need!
Can you do an examination of results based upon age, gender, and other parameters?
Great video! I wonder what do you think about gelatin powder as a supplement since it has exactly the same amino acid profile as collagen.
Wondering this, too.
The day after taking the supplement in your thumbnail shot, my hangnails clear up. Every time. I don't need more evidence than my self-experiments at this point.
I started to use collagen supplement three months ago… pretty much the same diet as thru the whole year, just added also Spirulina and Ginkgo and I have to say it’s a first time in YEARS that my cellulite on my butt got better. On left side in the middle I literally had like a hole and it drove me crazy and now I start to see improvement, definitely at least 30% better. I cannot imagine what else it could be then collagen as I didn’t change anything else.
Does collagen tighten skin
I suspect that the peptide's molecular weight influences how much it is broken down during digestion.
For years collagen powder has rid me of my back pain, so I'll keep taking it, thank you very much.
May I ask which type and brand you take? I have a long list of back problems that contribute to pain, so I’m hoping that at least some could benefit from collagen supplementation. I’m now considering surgery, but the doctor says that usually doesn’t relieve all the pain. 😥
Hey Brad I emailed the address provided in the study to ask about the type of collagen used. Will note if I get a response. edit: hydrolysate.
I started taking collagen five months ago, my horizontal split toe nails are no longer split. I also noticed that there is new hair growth albeit a very small amount.
When you look at the biochemical structure (i.e. a tight helix) and composition of collagen (i.e. mostly glycine, proline, or hydroxyproline) it is clear why some peptides or peptide combinations are more important than others.
From Wikipedia: the most common motifs (i.e. repeated structures) in the amino acid sequence of collagen are glycine-proline-X and glycine-X-hydroxyproline, where X is any amino acid other than glycine, proline or hydroxyproline.
These simple amino acids are necessary to support collagen's tight helical structure and other larger or more complicated amino acids are only incorporated occasionally.
Be nice to see a study comparing collagen peptides versus supplementing with glycine, proline, and hydroxyproline only
N group of one, anecdotal evidence here! Did this ( supplementing glycine, proline, lysine, zinc couldn't find hydroxyproline as a stand alone supp) while following a strict whole food, plant based diet.
Saw nothing positive. Until I jumped on the marine collagen peptide bus.
As an older female, my body needs all the help it can get. I'm rather annoyed with myself for sacrificing my skin and joint health on the altar of vegan dogma. But glad I woke up in time.
@@laurieparis2203
Thanks for the input! That’s interesting!
I was thinking about trying the same as I am also vegan. I have been curious about vegan alternatives that might also have benefit versus eating collagen. I was going to start with just the 3 amino acids and maybe try Vecollal. If those 2 approaches do not provide benefit I, like you, will try and see if I get benefit from the marine collagen. In the end, we have to put our health first and just do the best we can 😊
@@anthonymccollim3769 Hi Anthony. Yes. I want to do the best for myself, the planet and animals. But there comes a point whereby I have to put my health first. Being unable to function due to hip pain, allowing my skin to wrinkle bc I won't take a collagen supplement that mitigates those problems, is madness. But within the vegan community one such "transgression", and you're a pariah. Or you're told it's all in your head, it's placebo effect. Mostly by young vegans who have no injury or arthritis. So beware!☺️
And best to you with those supps you mentioned! I hope your body will like them. There's so much individual variation in body chemistry, what works beautifully for one can do nothing for another. 🌱
@@laurieparis2203
I agree with you. If it helps you, and there are no other vegan alternatives that work the same, then absolutely take it. Yes, there are definitely some Vegans that can be judgmental and only accept perfection. It’s not about being perfect, it’s about doing the least harm possible. Sounds like you are very aware of doing the best you can for the planet and that’s great. I don’t think you should feel bad about taking something that helps you when you have tried other options first 😊
I am also considering this myself
I wish I could take Collagen peptide supplement, but every time I start taking it I fall into a depression. I didn't know that's what was causing it at first, but one day I stumbled upon some information that links taking collagen supplements to depression. I think it was helping my sore elbow, but I didn't see any hair, skin or nail benefits.
I also have had this depression effect, but only from one brand I bought at Costco (possibly Biocell). I’m now taking Skin Rejuvenator with Verisol 10.58 oz | Bioactive Collagen Peptide Powder | Types I and III | Non GMO, Gluten Free Supplement | by Horbaach, with no depression side effect. I also have taken UC-II in the past without issues, but that I think may just benefit joints.
Which collagen peptides would be helpful for repairing fascia? To help with a hernia for example.
thanks for the video
I take collagen for skin and joints, not muscle.
Krispy Kreme does work, however.
Lol .
😂😂😂
🤣
Krispy Kreme injections directly into the heart ❤️
Agree 😊
Doctor Stanfield, what's the recommended daily dosage of collagen that I should take for skin elasticity improvement?
@6:15- We DO know that the study used "collagen protein hydrolysate", because that's what the study says. That's what many studies use. A powder made from hydrolyzed collagen. Similar to what we'd buy at the store (e.g. "hydrolyzed collagen peptides").
I have been taking the same brand for years, and feel that it helps manage my Bone on Bone Knees. There have been times that Amazon was out and I had tried a different brand. I can tell a big difference if I use a different brand. My nails are not happy, but worse yet - I feel it in my Knees. The Brand is: Wellpath Renew and is about $24 when not on sale.
I have been taking collagen for years but I don't know. I notice a different in my skin when I drink much more water than usual.
@ald6873
It fixes the skin problems older people has. Younger might not notice anything like that.
But collagen is in everything in the body. And not enough of that gives you weak tendons, blood vessels, cartilage, and even bone.
I think the reason for so much joint problems we have are because we doesn't eat much collagen nowadays.
There shouldn't be so many older people needing joint replacement operations, I think.
The key ingredient are the 2 amino acids Hydroxyproline and Hydroxylysine, which our body needs to make using Proline and Lysine. Collagen is by fare the most abundant protein in our body. So eating small peptides with these amino acids from collagen, makes it for the ageing cells much much easier to absorb as compared to making themselves, and make new collagen. So most of these studies are difficult to compare as the body needs also good quantities of Vitamine C and Zinc to make these unusual amino acids for new collagen....in short, collagen works fantastic for my knees and skin!
As I commented on your earlier video about collagen: I used for few years best available multi collagen, but didn't feel absolute any positive effect.
@DrBradStanfield from what age would you recommend one start supplementing with NAC / Glycine? What are your thoughts on the findings that it may impair muscle synthesis?
@marcocee197
There are no such findings!
What GlyNAC does is restoring the youthful level of glutathion.
Idiots can get the idea that it blunts the effect of exercise, because glutathion is an antioxidant.
Do they also think that younger people has diminished response to exercise?
NAC is also an antioxidant, with some health effects. But most of it is intended to be consumed building glutathion, isn't it?
I'm much more interested in the use of collagen peptides for joint health and healing than skin health, being a 62 year old hermit with osteoarthritis due to a combination of COL2A1 polymorphisms and hyperhomocysteinemia. Many over 60 would be much the same as myself, and be more concerned with joint and bone health than a few wrinkles. It would be good if your focus and videos could cover a wider demographic, and not overly concentrate on skin health and weight loss. Many over 60 really could benefit from many of these 'longevity supplements' for multiple reasons other than skin health or weight loss. For example I take 500mg of Metformin four mornings a week (not on my three exercise days) even though it's not suitable for weight loss, as my BMI is around 20. I take collagen peptides for joint health and to try to help my arteries recover from homocysteine-driven accelerated athersclerosis. I suppose I see wrinkles as a sign of deeper issues rather than something to fix up without correcting the underlying faults. I see it as a sign of insufficient autophagy as well as collagen dysfunction, with less wrinkles equating to a healthier metabolism with reduced ROS and AGE metabolites and increased glutathione. If hydrolysed collagen peptides are found to have no effect on skin health but are found to support joint health (and eye health) I'll certainly keep taking it. If found to help fix fine wrinkles but no other beneficial effects I'd possibly still take it but wouldn't bother having it regularly, as how well my body 'runs' is more important to me than how I look to others.
I have a number of genetic issues and would probably not still be here if I hadn't commenced a one-meal-a-day calorie reduced diet in 1990, at the ago of 30. I only really started on supplements a few years ago and for decades relied on diet and exercise to keep my hyperhomocysteinemia in check and keep my osteoarthritic joints as healthy as possible. In the past few years I've needed to add certain supplements to reverse the homocysteine-driven COPD and osteoporosis and athersclerosis and early-onset Alzheimer's. Hydrolysed collagen peptides seem to have very minimal risk of side effects, and may help offset my COL2A1 polymorphisms. Could you do a more comprehensive video on the use of hydrolysed collagen peptides, in particular the potential non-skin benefits, and also if it can possibly exacerbate some conditions? I have developed some type of hand arthritis since taking hydrolysed collagen peptides, similar to Dupuytren's contracture or 'trigger finger's, and have had lumps form in my palms directly below both middle fingers. It's probably not connected, but I have wondered if the lumps are collagen related and if hydrolysed collagen peptides effect those with collagen gene polymorphisms, such as my COL2A1 polymorphisms, differently than those with healthy collagen processing genes. Any ideas on this topic?
Statistical significance shows the odds of a result having occurred by chance versus as a result of what is modelled, it does not show strength of effect.
IE "significant improvement" and "statistical significance" are not synonymous. You could have a significantly insignificant strong effect or a statistically significant weak effect.
To put it another way, statistical significance is about measuring the accuracy of the model and not the effect of the treatment.
I used vital proteins for a month for joint pains at 53 and developed very painful acne on the back of my skull. After stopping, it took a few months for it to clear up completely. During the month of using it, my hair and nails grew extremely fast and my joint pain ceased. I recently tried it again just to see if the acne would return, and it did just on the back of my skull.
That’s weird. I also got cystic acne on the back of my skull around the same timeframe I tried Vital Proteins collagen peptides. Coincidence? I never thought it could have been that to be honest.
I went back to my preferred brand -Ancient Nutrition and haven’t had the acne problem. 🤷♂
When I stop taking collagen for two weeks, my hip pain becomes unbearable. I start taking collagen and the pain practically disappears in 1 week.
biolayne, menno henselmans and other fitness influencers were quick to condemn collagen as soon as they learned of this latest study, but I can't find anywhere in the paper whether any mention of collagen peptides. That's confirmation bias for ya.
The author told me hydrolysate
@@jaro6985 cool, where did he tell you, email?
I was gonna say. LETS ask the study authors, duh😮
I mean just taking it to make sure your body gets the amino acids it needs for the day is good enough. The amino acid profile in collagen is amazing with all that glycine and it's very easily absorbed and utilized. It's also easy to take, virtually no taste easily dissolves and doesn't have hormone issues or lots of calcium like the problem with whey. It's all around just good for basic health and I've noticed that effect especially when sick. So that alone has been reason enough for me.
I wonder if they've been taking collagen peptides in the form of a shake or smoothie. If that's the case, then the water is expected to increase skin hydration.
I'm still hoping for a diet and supplement video in relation to osteoarthritis.
OA is a leading cause of chronic pain in middle age and older people. Its becoming more common (perhaps triggered by an inflammatory processed food diet and obesity?)
Get off processed foods and sugar!
Turmeric or curcumin has pretty good evidence for reducing pain and inflammation.
For sure! Check out Dr Berg and Dr Ekberg for curing inflammation.
@littlevoice_11 Do you take collagen peptides for OA and if so, what have been your results? I'm going to start this week..
I took collagen peptides religiously for 2.5 years. Honestly, I couldn’t find any improvement to my skin even though I wanted to.
What was your diet and lifestyle? What was the brand?
Very interesting ! I was wondering what to take between collegen and whey protein as at the end we talk about amino acids. Answer is still not clear but I will take collagen and check I do overeat proteins.
If it is for wrinkles alone, then take a look at micro needling, the premises are that the body rushes collagen to repair the needle punchers and, in the process, rebuilds your sub layer, and also stimulates hair growth.
This channel is about general health optimization, especially during aging. I found it while being interested in longevity optimization. The hope is that collagen helps with some tissues and organs inside the body as well. Like you can tell people with a bad skin are likely to be sick, not only related to their skin. Then the other way around, good skin might indicate more benefits.
I took hydrolyzed collagen peptides (I&III) for 6 months. I noticed zero positive change and actually thought that it made my face look worse and my body look more bloated. Rather than mess up my body's natural blood chemistry and remain dependent on the extra collagen, I chose to discontinue. My family has good genes for natural longevity, so I'm hesitant when doing artificial things that may hurt me if I discontinue in the future. Dependency on a supplement should only be done if it's absolutely proven. Again, I saw no benefit and actually thought I started looking worse.
I tried that kind too. That Dr. Ax guy. And it didn't help my joints (specifically my knees) one damn bit.. I think that Dr. Ax and his little sidekick guy are a couple of con artists.
I had the exact same experience as you did, but I also had an additional problem- I got leg cramps. I only took the collagen for a month or two, but that was enough time to tell me to stop.
That's nonsense. Collagen does not cause that, it's a freaking protein
I take collagen peptides (The Andrew Lessman Marine that is on the beginning of your video), but I don't take it for the skin, I take it for joint health. I have been taking it off and on for 5 years plus now, and when I don't take it I really feel it in my knees (I'm in my 50s and work physical labor), when I resume taking it my knees feel better. Thank you very much. .. I take the marine kind because I think it works better than the bovine kind.
I too take collagen for joint health and like you I have noticed a difference. About four years ago my knees started to become fairly sore, possibly due to overtraining on my exercise bike. (I am 62.) I tried ultrasonic treatment, a massage gun, a few sessions with a chiropractor and glucosamine tablets and none of them really worked. I then started taking four scoops of collagen a day with my beverages, plus glycine, and the soreness has almost gone away.
@@dpstrial I'm glad you found the solution. And Yes, I do notice a difference if I take more or less of the collagen peptides. You take 4 scoops a day, that's alot. I only take 1 to 2 scoops per day and sometimes every other day (because of budget reasons). But when I take 2 scoops my knees feel even better than if I just take 1 scoop. So 4 scoops should should work even better. There's No Doubt That Certain Collagen Peptides Work.
@@bonanzatime I read somewhere that it was dose-dependent and my experience confirms this. I shall continue to take it. I recommend "The Collagen Cure" by Dr James DiNicolantonio and Siim Land.
@@dpstrial Siim Land, I'm familiar with. He's a Smart kid👍
Very interesting research,
I take collagen peptides,
Thank you so much for the video.