New Study links Omega-3 to Heart Problems… but, it isn’t the only one.
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- Опубликовано: 4 июн 2024
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References
[1] DOI: 10.1136/bmjmed-2022-000451
[2] doi:10.1001/jama.2020.22258
[3] doi:10.1161/CIRCULATIONAHA.121.055654
[4] doi:10.1016/j.eclinm.2021.100997
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#omega3 #omega3benefits #atrialfibrillation
AMENDMENT: 0:25 - accidental addition of 'The Trooper' instead of 'Run to the Hills' by Iron Maiden. I am ashamed of my blunder as a crazed metalhead! Please forgive me, oh Maiden.
up the irons! Any Maiden is good!
God forgives. Maiden doesn't.
dont get on any planes Bruce Dickerson is flying
LOL
Craziest Physionic Amendment to date
Omega-3 supplementation study that did not control for omega-3 intake. Yeah, sums up majority of the nutrition studies. Completely useless data.
And still people complained when Peter Attia basically said most of the field of nutrition science is a joke (my words).
@@pedro.almeida And yet studies consistently show that people who follow dietary guidelines have lower mortality than those who don't. Attia always gives the impression that his real criticism of nutritional science is that it doesn't always validate his opinions.
Not useless; there is a place for this kind of study. The problem is that science gets reproted in the general media by people without any science training or background and they don't understand there is no single kind of evidence you can make health management decisions based on, and that every study has to be put in a larger context. This stuff is complicated and you need to construct the big picture out of bits that are in themselves inconclusive.
My biggest concern with this study is whether the omega-3 users and non-users represent comparable populations at the outset. Perhaps people with a reason to be concerned with heart disease were more represented in the user population.
@@pedro.almeida Attia is definitely a joke..
Wait till you evaluate virology and look for "controls" in their cell culture isolation experiments. I think you know by me bringing it up what shocking results you'll be forced to conclude if you are a genuine science respecting person.
When you read the study carefully, you’ll notice that a deficiency in omega-3 can also lead to heart problems. Even more so than when overdosed. Therefore, it’s important to stay within the normal range. You won’t exceed the normal range by consuming up to 2000mg of fish oil. In case of doubt, simply request an omega-3 blood test at the laboratory.
I presume that means 2000mg of EPA plus DHA, since the oil itself has varying amounts of omega 3, depending on the source.
The study shows those who supplemented had increased risk. Says nothing about “over dosing”
This Study must be from the Food Industry, they want to sell their omega 6 rich fats, Soy, Corn, Sunflower, Rape Seed Oil's...
The Inuit ate nearly only very Omega 3 fat rich Foods, for thousands of years and they have been very healthy, as long they stayed on this Food intake.
Exactly - everything in moderation. I am getting so tired of first it's good, then it's bad and then as long as you take in moderation.
I’ve been taking 2000 mg of omega-3 supplement for 3 years to treat my blepharitis. Unfortunately, my LDL cholesterol went up. I’ve discontinued taking it and will see in a few months when I get my blood retested if anything has changed.
Anecdotal experience: 15 years ago I Started taking Omega 3 supplements and did good so tripled my dosage to about 5,040 mg (six soft-gels) and got arritmias, pounding beats, scary symptoms. Went back down to 2 840 mg soft-gels and everything back to normal again. I’m over 60 and take no medications - my BP is 115/70 average of all readings - resting pulse 50.
Thanks! Hit the upper Dosage limit! Adjusted. Thank you for sharing.
Wow, either of those seem like crazily high amounts - over-supplementing?! I take 1300mg fish oil gel once per day of which is 1040mg omega 3. This seems a sensible amount, and similar to what you would get naturally from a portion of salmon.
@@feled01 if I would eat Salmon, Mackerel or sardines but I don’t so I take 2 capsules daily (15 years now). I don’t follow Peter Attia but he shared this before: I'm taking four of these capsules a day,” Attia reveals, and at 1200 mg per capsule.
I’ll stick with my 1,640 mg daily.
Why would anyone in their right mind take 5g of fish oil?
@@AT-bq1kg ask Rhonda Patrick. she takes 4-6 grams daily.
I hate how they use the terms "fish oil" and "omega 3" interchangable, as if they're the same thing!
yeah there is also algae oil, which doesn't have the mercury in it that fish oil does but still likely has all the benefits.
@@rinkuhero True, also shrimp one
@@rinkuheroI mean fish oil in the end is just recycled algae oil.
Because it is, for any relevant purposes. Just because you use some obscure nonsensical source just to be different because it validates you insecurity of needing to sound intelligent, doesn't mean societal conformity should end with you.
@@user-is1yo3nj8p 1000 mg is simply the weight of the oil. If you look at formulations of these supplements each have differing amounts of omega 3, as well as EPA and DHA content. They're not all created equal, or so their manufacturers say. I don't know what the rest was in reference to.
I didnt know that Omega 3 changes the compositon of the membrane and influences the sodium-potassium pump. That's an amazing physiology lesson! Thank you so much!
I found it fascinating, as well. Thanks, Carmen.
@@Physionic Omega 3 changing the compositon of the membrane and influences the sodium-potassium pump. - a good thing or a bad thing ?
@@Physionic Yes Sir. Could you take a similar look at that fifteen carbons chain (I think sometimes referred to as C:15 perhaps...). This is a structural saturated fat in the membrane. Proposed as a new addition to the already very long essential fats list ... heretofore, length of TWO. And these two are polyunsaturates. Proposed addition is SATURATED. And this comes with that cool backstory - dolphins serving in the navy getting metabolic syndrome / dementia type of diseases similar to what humans might get ... with the parallel story of the exhausted supply of candle fish ('hooligans') that used to provide a significant proportion of the dolphins' total C:15 intake.
Also, deuterium in whatever concentration can surely not be ignored in light of the fact that the sheer volumes of protons passed through the ATP synthase machines of the mitochondria renders even the smallest traces a potential issue. Indeed there is now ample evidence to support this.
@@charleyhoward4594 Seed oils do much the same. Then you get double chin etc. with too much fluid in your cells. Only use organic butter (better balance of different fatty acids) in your diet to avoid this, or if damage already, tighten your skin with higher portions of this butter.
I have a very curious mind, always have, and one of the reasons why I have subscribed to your channel is because you are able to explain extremely complicated studies for someone like me. Keep up the great work.
Thanks, Raeanne
That's like saying oncologist patients are more likely to die from cancer.
Myold Grandfather used to say Everything in moderation. lived to 85 My Grandmother on my mums side ate simple home made foods in modest portions and had a glass of Sherry every night She lives to 90, and her father used to say always leave the dinner table wanting a little more. A saying my mum taught me was- After Breakfast work a while After Lunch rest a while after dinner walk a mile.
It like my father technique. He said plan during eating. Stop eating when think if finish now and drink a glass of water after it you feel exactly full....not eat till feel full and when drink water after that feel bloat.
Why is your grandmother at all relevant to a discussion of a certain scientific study?
Good luck with consuming alcohol every day! Maybe you need the story as an excuse? Sounds like addiction to me 😂
Dr Rhonda Patrick had an expert on fish oil on. Dr Bill Harris was saying fish oil increased your risk for A fib but paradoxically decreased your risks for both stroke and heart attacks (both caused by A Fib)
But only the free fatty acid form, not as triglycerides, right?
@@wocket42Do you recommend a particular brand? 🙏🏻
Kinda like how exercise causes inflammation and damage to the cells but helps them stay healthy longer and reduces inflammation overall.
@@nickmagrick7702😳
What about krill oil? Is it a better alternative?
Thanks for reviewing this information -- very helpful!
I'm impressed that someone so young can appreciate Iron Maiden.
#1
The Greatest Metal Band of All Time!
My 29 year old son was raised on Iron Maiden. I put earphones on my belly.
I met a 20yo who liked Mozart and Beethoven. He's dead now.
It totally makes sense as every medicine and supplement is going to have an upper limit. The body is always trying to keep everything in balance So you can drink too much water, etc.
I agree!! There is an optimum / healthy margin for everything, balance is the most important! The whole being greater than the sum of it's parts! And as you rightly eluded too, Too much or not enough water, can kill you!!
Yes, more does not = better.
Even water can kill us if took too much
Great coverage on this topic!!!
Thanks. You did a great job, as usual, of hitting the key data points, strengths and weaknesses, and relevant references for this study. As always, it helps put things in perspective and provides the story behind the story.
Thank you for the work you put in for us to get educated by.
Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants
I started taking Natto after my triple bypass. I hope it helps
Yeah, nattokinase has been added to my stack since it’s horrible to eat - and I do consume & make lots of other fermented foods. Better to get useful food components from the food, if you can, rather than spending on plastic pots and marketing generally speaking.
@@gtbigdog3507 are you eating natto or taking nattokinase?
@@defeqel6537 nibbling..
Another factor I think that should be considered is the quality of the fish oils. Since supplements are not regulated, they could be rancid (oxidized). I think this could lead to increased inflammation in the body. Same with olive or avocado oil.
Exactly, no info about how they're stored before purchase, I see them just laying on the shelves in pharmacies, ordering them is even more concerning, even after all of this manufacturers may still mask the smell or taste, better off eating the source itself
Yup, that's a huge variable, another is the population studied; if you are already on statins, which reduce clotting, adding O3, which reduces clotting, to the mix, might indeed do more harm than good
There doesn't appear to be any evidence that shows rancid oils have any noticeable adverse effects. The primary effect seems to be that it reduces the amount of omega 3 that is being consumed.
@@dimseablue136 Once they're in the capsules they're pretty much sealed. On top of that the packaging they're in gets sealed. If there is oxidation it probably primarily happens during manufacturing.
I can't eat the source unless there is some way to mask the disgusting taste and smell of fish.
@@defeqel6537 Based on the information in the video that should all be irrelevant to atrial fibrillation.
I always enjoy you videos, the information is always great.
Thanks for this video. Coming from a guy that’s prescribed the icosapent ethyl pills. I did hear of this study. It seems like a new study comes out all the time that makes me question what I’m doing. There’s so much nuance to these headlines so thanks for breaking this down. I look forward to your results based on your research.
There's always a new study in the world of supplements saying the opposite of another study. I'm going to keep taking my omega-3's.
agree. I'm gong to keep taking your omega-3s as well.
@@MrTweetyhack Mine? Wouldn't you rather take yours?
Yeah, i just take everything every other day as i think too much of anything isnt good. Ill go on small breaks for things too.
@@andrewhall7176 yours taste better.
I havent bought a supplement in over 3 years, and I've never been happier.
It would be great to look at algae-based versus fish-based since fish oil may be contaminated and far more toxic than just going straight to the source. After all, fish get it from algae. It would also be great to compare people who just eat a well-balanced variety of whole vegan foods including nuts and seeds. After all the RDA is for ALA not elongated fatty acids unless you're a breastfeeding infant...
Dr Tim Radak has a very deep dive talk on this on my channel but it's a few years old. There is a link to his site where he may be keeping up with the information.
I don't think even algae is safe.
"A new study in the Pacific Ocean suggests that algae at the water's surface absorb mercury from the atmosphere and then sink to mid-depths, where they decompose and release methylmercury, a highly toxic form of the metal that poisons both fish and the people who eat them."
But the body uses the other omega 3s, which we either have to get from sources like fish or algae or eat vast quantities of ALA. It's clear that as a source of all the omega 3s the body requires the ALA RDA is woefully inadequate. Also since atrial fibrillation is explained by the effect of an omega 3 on the cell membrane why would we need to introduce an additional toxin hypothesis?
@@loganmedia1142what evidence do you have that the RDA is woefully insufficient?
It would also be great to compare that with a whole food carnivore diet too
@@MrSidReal there's no such thing as a whole food carnivore diet. A significant amount of energy is lost when you eat an animal because the animal got their energy from plants. And then when the animal metabolizes the plant for that animal's body specific needs energy is lost, which might be why plants have on average 64 times more antioxidants to offset metabolism. This is also why eating animals is so unsustainable and uses about 80% agricultural land for only about 20% global food intake. And that's why they inevitably end up in concentrated animal feeding operations of which there's over 200,000 in the us alone. And this is of course more of a process after they've been artificially inseminated into existence which is another process. Then the animal that you're having killed for your mere taste pleasures goes through a slaughtering process, a cleaning process, a packaging process, refrigeration and transportation before It goes through a cooking process and finally is seasoned with herbs and spices which would be about the only whole foods you might get in the mix.
Thank you for your work, dr
i waited for this video to be after your comment on Dr. Brad Stanfield so much! just waiting when i finish learning in uni and then i will join the insiders!
This is a good reason why i takevery little notice of most of these studies.
*Hey! Let's run a multiyear study on a single variable without controlling any others! Ignore dosage, frequency, and all other factors! Just ask!-That'll be good enough!*
*Woohoo! This will be valid! Tenure, here we come!*
😊how wonderful this channel was recommended glad it was!! I love it!
Seriously thank you for breaking this down. The headlines of this was confusing as heck and I've taken omega 3's my entire life for the benefits of brain/cardiovascular. This was a great breakdown of everything.
I can only mention anecdotal evidence. Been taking 4 mg omega 3's for about 6 months as part of my stack. Started to get finger and foot cramps on left side. Also experiencing a shortness of breath/ irregular heart beat. Added magnesium which reduced the cramping and breathing problem dramatically. After seeing this video will reduce the dose of the omegas to 1 gram and report if it solves the cramping/heart beat prob in the near future. Appreciate your work sir!
4 mg won't do anything. I think you mean 4 gram.
4 grams fish oil or 4 grams combined EPA and DHA?
@@meltedsnowman9637 you just need 1gram of each EPA and DHA, so I think he meant 4gram regular fish oil, that would give around 1gram of each DHA and EPA.
I'm drinking tea, taking my omega 3 whilst watching this. Thanks for the reminder 😂
Thank you!
First: as a trainer and supplement-science nerd, I am very happy to discover this channel today. I can immediately see that you are my kind of person!
Second: I read the study in question. It seems the study affirms that a moderate dose of Omega-3s is beneficial.
I've been taking ~6G per day for the last couple of years, for heart health, and as an additional support for my intense body-training regiment. But based on this data, I might be wise to reduce it to 2G per day.
My conclusion is that by having 3 portions of fatty fish per week instead of potentially rancid supplements, we can avoid such risks, and still maintain reasonable level of fatty acids. I also try to get one tablespoon of flaxseed, Chia seed, and a tablespoon of olive oil. I hope that using natural resources like this (and with the hope salmon I ate is actually heavy metal free as claimed), we can still meet the bar without supplementation.
The same goes for other micro-nutrients. I am hoping to minimize the supplements I am taking and with low doses, and try more veggies and fruits.
Eat sardines for less heavy metals.
I completely agree with you. And what do you think about seed oils regarding Flax and Chia? Wouldn’t they be bad as the other seed oils we avoid now? Greetings
@@rodolfocampa95 I try to eat grounded flax seed and Chia, and it is only one small spoon for each, breakfast and dinner, respectively, with olive oil and a teaspoon of honey, all mixed.
Those seed oils do not get rancid as easily, as Olive Oil, if we do not heat, it is mainly ok. But still, I think the best bet is to eat the grounded versions and only in smaller amounts.
I heard they have lower conversion rates from ALA to DHE/EPA. But I will be satisfied (for now) with 3 meals of fish + whatever conversion I got from grounded seeds. And sardines maybe one of 3 fishes.
I wouldn't eat any seed, absolutely pointless for me, I have a rule of thumb, all nuts and seeds are high in o6, if not then high in oxalates (or whatever other toxic compounds), if not, indigestible fiber, if not, I still don't want to invest in any, plus any oil high in MUFA or PUFA has the same capabilities as the supplements
@@dimseablue136 Flaxes have o6?
What about walnuts and pistachios? I heard they have pretty good stuff in it, of course, walnuts should not stink like corrosive metal as some do in the market...
I grew up with olive oil in West Turkiye, so I still munch in it. I must say prices are very high for it, compared to what it used to be, especially in the USA (where I live now).
Already liked the channel, but the Iron Maiden quote and sound clip has made me a fan for life. 🍻
Bill Harris did a critique of this study on the Omega Quant Lab channel, its called 'behind the headlines'.
It would be really interesting to hear your take on what he is saying. Obviously he has a special interest in this area and financial gain to be made through his associated company, but he is also a fatty acid researcher.
Well, i was suffering from heart arrythmias. Tried cutting out everything I could think of. Then, i stopped taking Omega-3s and the arrythmias stopped completely. I still eat Salmon once a week and doesn't seem to bother me, but supplementation did affect me. Just saying.
It would have been interesting to hear how much you were taking and for how long
Eating more fish would probably have the same outcome.
@@katgod , my thoughts exactly!
Tòo much of anything is Never a good thing!
Thanks for the info on this. I do take a lot of omega 3 but I'm not to worried about it. I may consider lowering my dosage some.
I give up. Every time I take something that's supposedly the new super healthy thing to take a study comes out saying the opposite.
Tell me about it 😢😢😂😂😂😂😂
The feeling is mutual, however if you read into a lot of things it ends up making more sense, and unless there is bloodwork and continuous monitoring, you can just give the Study very little weight. O-mega 3 are still healthy
@@elgaen555 Honestly, I'm at the point I don't think you can believe anything these people tell you. For example, You're told that vitamin K2 helps prevent Harding of the arteries by carrying the calcium to the bones where it belongs. Then a new study comes out saying no evidence of this was found. We're told that vitamin E is wonderful for years and now that it causes cancer of the prostate etc. And what do they do with it? They put it in every cereal known to man, along with BHT etc etc. I could give you example after example of the double speak coming from the health community of Doctors and researchers. If you take these people seriously, there is literally nothing safe to eat or good for you. I've had it with their bs, they simply have no idea what they're talking about, any of them.
A questionnaire... Thanks for mentioning it so early, I skipped the rest.
Except he does discuss two other studies that also link the same afib symptom to omega-3s and a physiological mechanism to possibly explain it. Science is in the exploration and the nuance, but you can absolutely wait for someone to give you the bullet points decades later. Probably still won't be 100% sure of anything though.
I would barely be able to use my joints if it was for fish oil, i have no choice but to take it or ill be in pain.
I enjoy your work. What comes to mind is the diet of all the participants of the study. It seems there is no way to isolate the effects of other PUFA's ingested from the Omega-3 fatty acids. This is not a comprehensive study since it doesn't take into consideration the physiological compensation going on within the individual patients/study members from the wide range of foods eaten by them.
Very good additional flaw in study. Your point I think is that some of these people in the study take Omega-3 fatty acids to compensate for other poor diet choices.
Thank you for the explanation ❤ on cell membranes. My father has afib and this may help me to solve another mystery.
On the question of whether this is a dose issue, I thought it was interesting that the study that found no deleterious effect was using an 800 mg dose. That is comparable to a serving of salmon (1.1 g/serving) or roughly half a serving of sardines (1800 mg). Consumers have a "more is better" mentality, and it's not hard to find supplements that claim to deliver 3000 mg or even 6000 mg per dose. Also omega-3 is only about 20% of the fat content of fish, so taking an 1800mg supplement isn't the same at all as eating a serving of sardines.
My biggest concern with Omega-3 supplementation is that consumers are relying on an effectively unregulated supplement industry. You don't know what's in the capsule -- whether it's contaminated, adulterated, rancid, or even whether it contains any omega-3s at all.
Thank you, you summarized the issues with this data much more concisely than I could have.
Seems to me that its best to get most nutrients from whole foods.
Of course people should be reading the labels to determine the actual omega-3 content. Eating oily fish at least twice a week is about 500mg of omega-3 per day. People who really like fish probably eat even more.
If I ate fish I would not really know what was in it either.
Studies are useless because everyone has a unique body with unique processes that need unique regiments.nuff said.
Please do a collaboration on this topic with Jay Feldman/Mike Fave from Energy Balance Podcast, that would be really interesting 👀
Ray Peat was writing about this 20 years ago. Using studies older than that..
I woke up several times, thinking I was dying of a hearth attack. This was 2 years ago and I took 3g of omega 3 in the span of 4 months. These "attacks" happened within that window and did last
Did it happen after taking Covid vaccine or contracting Covid? Also did you up you vitamin-D like many of us did due to Covid?
@@mbarlev it happened about 6 months after my second covid vaccine. I did take vitamin d, 2000iu’s with the omega 3.
@@thomk3282 I had palpitations which are benign arrhythmia and dont feel like heart attack but still. I attributed this to either stress I experienced at the time, covid vaccines and over does of vitamin D. I Dialed down the vitamin D but continued with omega 3 and upped my magnesium and my palpitations went a way for the most part. When comparing to similar incident of a family member the common ground for the palpitations onset and subsiding was time from covid vaccines. I am bout 50 y/o. Also there is a channel (I forgot the name) of someone who had lot's a palpitations and Afib episodes and nothing helped and was on the verge of abbelation. He got rid of this by supplementing with electrolytes more specifically magnesium and potassium. I would look it up. Not a medical recommendation of course but may be worth it to compare notes so to speak.
I been using Omaha 3 for years , with no problem at all . Nature made fish oil is what I use . They removed mercury.
What brand? I use Nordic and so far no problems at all.
They will push statins, while ignoring marginal A1C issues, carbohydrate intake, actual Mg status, sugar intake, inflammation, etc.
yes, how dare they make recommendations based on decades of scientific evidence?
@@tomgoff7887 How dare they make recommendations based on profit?
How to reduce inflamation?
@@nenadcubric2663 Pay attention to this gentleman, Dr. Cywes, Dr. Ken Berry, Dr. Eric Berg, many, many others.
Then you have all these other people pushing red yeast rice supplements...which is a statin but not as controlled or tested
I had 75% blocked carotids, years back, and my mainstream Dr. had me take Fish oil and RYR for three months and I did nothing else and they cleared to about 10% in that span of time.
That's no mainstream doctor.
You woulda had stents by now.
@@mballer True LOL😆
This is why we have Meta-dudes like you. Waiting for the next chapter. Chop chop.
@@mballer He seems to go back and forth a little over the years. I think his controllers get wind he is pushing things other than drugs at times. Then other times he stays away from things alternative all together. Other times in the past he would whisper alternatives like there is a recorder in the room. For several years now he mentions nothing alternative because he has an actual "Stenographer" putting in everything says to each room. He hasn't talked alternative things since he has had to have that.
2 grams of fish oil thrice daily. A lot of fish oil at that.
I am Scandinavian and we eat lots of fish but grew up in canada, lots here too, people think i am in my early 20s. Fish oil works, and make sure you exercise.
Well, its just a correlation. People who take anticancer drugs die of cancer more than those that dont. Because they have cancer. Those that supplement with O3 are those more concerned with their cardiovascular health. Sometimes with a reason.
O3 is already in regular use - and I don’t think you should be using the abbreviation - it conflates Omega 3 with a highly reactive, oxidative substance.
Use Ω3
logic 1.0.1.
Exactly! Thank you...
That's what I'm not sure about, what's the lifestyle of these people?
Worthless study.
Not all supplements are created equal.
Too many unknown variables.
Need actual blood/cell omega level testing.
Why were people taking omega 3? Heart health? Were they also doing other things such as unhealthily reducing salt intake?
Were they on other medications?
Who was getting their intake from fish and other foods?
For anyone to be strict on their intake over years, they must have been very well chosen.
Maybe I missed it, did they reference weight and activity levels of participants?
We're they using supplements as a surrogate for getting of the couch?
Given the size of the participants I would assume the majority have used rancid oil and called it omega 3
Careful now, you're asking reasonable questions!
It was designed to give the result that it did. Funded by Bill Gates - say no more.
Why is everyone coping so hard in the comment section? Read some Ray Peat, he already had this figured out. It's called lipid perxoidation
@@ArimaSenne1
What do you mean "coping"?
we've known for ages that omega 3 shows slight cytotoxic effects against certain types of cells under certain conditions. This is not really news. In fact it's a useful trait as many of the cells that it shows preferential toxicity to are cancer cells.
On the bad, at high concentrations, omega-3 fatty acids can be cytotoxic to neuronal cells, leading to oxidative stress and cell death, although lower concentrations are generally neuroprotective. Similarly, high doses of omega-3 fatty acids have shown cytotoxic effects on endothelial cells, potentially impairing cell function and viability. It is important to note that the cytotoxic effects of omega-3 fatty acids are highly dependent on the concentration, type of fatty acid, and the specific cell type involved.
But the good, Notably, omega-3 fatty acids, particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), have demonstrated cytotoxicity in various cancer cell lines, including breast cancer, prostate cancer, and colon cancer cells. The mechanisms behind this cytotoxicity include the induction of oxidative stress, apoptosis, and the inhibition of cell proliferation. Additionally, omega-3 fatty acids have been shown to induce apoptosis and reduce the viability of leukemia and lymphoma cells. However, the effects are not limited to malignant cells.
don't forget, "All things are poison and nothing is without poison; only the dose makes a thing not a poison." - Paracelsus
I want to know what is a high or low dose. I have seen supplements with varying amounts of EPA and DHA levels with varying mg of oil. Rhonda Patrick said something like 2 grams so ive been taking roughly 2.5 per day since a few months now. Haven't noticed any heart issues yet but i also have a light workout routine and I'm in and out of ketosis since i keep on low carb (under 60g/day)
Anecdotal experience: 4 grams daily fish oil gave me at one point, heart pains. I poke a hole into the gel and it smelled really bad. I stopped taking it and the heart pains went away, mind this was an expensive premium brand with certificates.
Later I bought another premium brand, poked a hole before consuming and it smelled fresh, so I took it. After 3 weeks I started getting heart pains again, I did the same test again (poked another hole in the gel capsule) and sure enough it smelled awful... I stopped taking it, and pain went away after 3-4 days.
It's a shame because I was getting good brain improvements and decreasing joint pains from workout, so I will try again later with vegan omega3.
Were you keeping the capsules in the fridge? If not they will oxidize, hence the smell
Eat fish...
@@andy78226 always in the fridge, I am a health nerd so I am very aware but thanks for the tip 🙏
But thing is, the vendor do not keep them in a fridge and even tho the gel capsules are air tight and usually even have added anti oxidants, they still go bad fast once you open the bottle.
@@Icenflamesrush you need to eat a lot of fish every day to get same benefits as you get from 4-5 grams of omega3 (+1000mg DHA and EPA).
@@orion9k you better put them in the freezer, because otherwise they oxidize too fast. Also did your brand put the totox level on the package? Its the level of oxidation at the time of production, which is important to know before you buy it.
It is quite amazing how inconclusive the DHA/EPA results have been for decades. I continue to take 900 mg DHA/EPA but I'm not strongly convinced that it does me any good -- or any harm.
I'm not normally against playing The Trooper, but I think this called for Run to the Hills.
Having watched this channel long enough, I have to think, "that's the joke.."
@@danbance5799 Might be, the deadpan humor of this channel doesn't really hit home for me. I'm just here for the graphs and statistics.
Im takeing Omega 3 now every day !!
Not surprised, I started taking them when I heard O3 reduces inflammation compared to O6, took me a while to learn they can be rancid due to terrible production then also had concerns about the storage conditions, THEN also had concerns the manufacturers would try to mask the smell or color
Confirms the old saying, if a little is good, a lot is not always better. Even too much water can disrupt sodium potassium channels, so it makes sense that any substance and too high of a quantity will do that.
Just survey the cardiologists that prescribe omega 3 fatty acids. The prescription form is used as a drug to lower ldl. Doctor's have been prescribing then for decades. Usual dose is 4gm a day.
death by doctor. if a doctor prescribes it, run.
Frankly, if it's true, I'm not surprised. I'm a firm believer that omegas should be consumed in their natural whole food delivery systems. Never isolate them. Eat wild caught salmon 2 or 3 times a week. Nature is brilliant, balanced and offers synergistic ratios with other nutrients and compounds in the fish that work in harmony. So the sum is greater than it's parts.
excessive consumption seems unnatural … not enough people appreciate that the sweet-spot of health is homeostatic balance. few things other than exercise are better with “lots more”
@jamesstrom6991 that's exactly right 👍
@@jamesstrom6991And exercise can be overdone as well. I used to have a very physical job and it depleted my body tremendously. Very low potassium, a kidney stone, etc. I couldn’t gain weight no matter what I ate and drank, which sounds good, but being thin doesn’t mean you’re healthy. Most people in this day and age do need to exercise a lot more, but some people actually need to cut down. Everything in moderation, including physical activity.
@@cryingforthemoon truth. take care of yourself brutha. my youngest is 20 doing tree work and i talk to him all the time about pacing his exertion and how it can accumulate. fortUnately he has his own business so he can take rest days.
Correlation is not causation. The paper shows an association between omega 3 and heart health. But the most likely reason A is correlated to B is not that A causes B but that A and B are a result of some other factor C. Medicine is particularly prone to this mistake. Research is needed to determine and then prove a causal mechanism.
Please respond who funded the study. That usually tells you what you need to know. Because they can make a study say whatever it wants to push an agenda.
Thanks forthe review. Most informative.❤
What type of stroke risk was increased? hemorrhagic or ischemic?
I am 68 and been taking Omega3s for decades … still ok with no afib or diagnosed heart disease.
In addition I eat fish multiple times a week.
Let's get some black fermented tea benefit videos ? Green teas daily. Great information on fish oil. Watched after Dr. Brad's breakdown.
Very interesting. I’ve been taking fish oil for probably around 12-14 years now. I saw some evidence that it can reduce inflammation, but that it should be taken at dosages much higher than the typical 1 gram. So I’ve been anywhere from 8-12 grams per day. Before I started, I had been having chronic bronchitis. I got bronchitis 3 times in about 15 months, and each time it lasted for about 3 months. I think it may have been some form of asthma, as it got bad at night. However this went away after I started taking the high dose fish oil. I did get bronchitis a couple more times over the last decade. Each time I doubled my fish oil to 20 grams per day, and it went away within 3 weeks (instead of 3 months like previously). One thing I did seem to notice is I would have a pounding heartbeat while on it. Not fast, just felt extra strong. Anything I could find about that suggested it was nothing to worry about. Since this study came out, I have taken a break from the fish oil. Heartbeat is currently normal. I’ll probably take it again but not at the higher dosages, or maybe I’ll just temporarily take high dosages to get over an inflammatory condition like bronchitis…
I am about to watch the video but I am wondering is related to non-purified fish oils. My cardiologist recommends Vascepa but it’s not covered by my insurance unfortunately.
Ask to speak to your cardiologist's tax accountant and/or financial advisor. May shed some light on their recommendations.
So what does this mean for Cod Lover Oil?
I’ve been taking roughly 4g/day. I did have a weird heart thing on the first week I started. Now in the 1.5 months I feel really good, and no heart palpitations since. Anecdotal obviously but just wanted to share
When you follow up on this info, can you address the fact that numerous longevity experts state that 2g of omega 3 per day will help you live 5-8 years longer, because of the decreased mortality. They site several studies backing this claim.
Thumbs up for the Iron Maiden reference 👍🤘
that was my biggest take away too
but if we cant take a lot of Fish oil for example, how else are we gonna achieve a good omega3 to 6 ratio? would it be the best option to actually pay more attention to consuming less omega6 instead?
The main point seems to be that we don't need huge doses of the omega 3s found in fish oil, and that those high doses might carry some risks. There is also quite a bit of evidence that the omega 6 to omega 3 ratio matters little, if at all, if you're consuming adequate quantities of omega 3. Adequate here meaning enough for your body's needs (cell membranes etc.)
It is important to remember that the human body needs EPA and DHA, but can't make either and that conversion a vegetable omega 3 like ALA is very inefficient. So we must either get our required omega 3s from food (fish/algae) or supplements.
bingo
So thanks to this video I have a better understanding of A-Fib risk. I would be curious to hear of the benefits of higher doses. For instance, a family member takes high doses to treat chronic dry eyes. I realize that may be a lot to unpack though.
Excellent point. I take higher dose of omega 3 for dry eyes. It makes a difference. If I skip a day, my eyes get so dry.
@@helios4425 Same in this situation. She takes very high doses of a pretty expensive omega.
@@helios4425 That seems a bit like a placebo effect. I don't think the blood levels of omega 3 would drop that quickly.
@@user82938 I know. I wish I could explain it
Apparently, people who eat a lot of oily fish are in danger. Hmmm.
Always check the funding / possible conflicts of interest of the authors of the study. There also was such a nonsense one about intermittent fasting increasing the risk of heart problems by 91%...just ludicrous.
For the past several years, my Dr at Kaiser Permanente has had me taking 2 tablets of Omega-3 every night to curb my triglycerides. They are 2500mg (1500mg EPA, 568 DHA, 50mg DPA), heavy metal tested, and I keep it in my fridge. Never had a burp that seemed in the least bit rancid. I'm 44 now, been taking 2 every night since I was 37 or 38. I haven't noticed any adverse side effects. So either I've been lucky, or I'm just not predisposed to Afib. Something to consider tho. Perhaps I should take just one 2500mg gel-cap a night instead of two.
I eat canned mackerel or sardines in water daily for omega 3. They're too small to be farmed and swim too deep to worry about mercury. My skin went from dry, flakey, bleeding around knuckles and cracked heels to soft and smooth within a few weeks of daily consumption.
The postulated "mechanisms" are interesting, but might point out that "Omage-3" is but one of many, none the least of which would be the Electrolytic charge influenced by the "Sodium Pump" system, which is established by a ~ 2 to 1 ratio of Potassium to Sodium. It would be interesting to know of the sample base, how many of those supplementing with Omega-3 were also operating under a "Low Sodium Diet", thus adversely impacting the required Potassium-Sodium Ratio.
Rhonda Patrick shared a study that showed poeple who smoke and take omega 3 has faired better from a mortality aspect vs poeple who did not smoke. The results were significant.
Just shows how bad study design give random results.
Nicotine offers a number of documented health benefits; smoking simply is not the preferred delivery mechanism.
@@OTatime In addition to overwhelming negative health effects.
Now I gotta start smoking... Damnit.
@@user255 no duh…obviously
I have been taking 2 grams a day for 40 years, I will continue to do so I'm 75 years go figure.
me too, 74 and I take 6 grams a day
@@YarisWRC2
Holy moly! 6 grams?
I'd like you to be studied.
2gr is not a problem
@@triphan5842 Source? Another MD yesterday said the threshold is about 1000mg, and he just 840mg, so where are getting 2000mg?
If I take 6 grams daily, after a few days it starts to leak out of my butt or when I poop it's fishy lol. Happened when I was a teenager too. I found that the only thing that helps is taking TUDCA and increasing carbs.
Since I don't do too many carbs I just stick to 1 or 2 grams whenever i take brain boosting herbs and I don't run into leaky butt.
anecdotal experience:
omega3 shortage make me zombie-like quite fast.
Was eating 1 sardines serving a day + fish oil, total around 4g.
Switched to plant-based, vegetology supps, currently running 3-3.4g/day, upper limit I tried was 4g.
Started from 1.6g/day, and it was insufferable.
Never had any heart burns or smth like that.
I intermittently take omega 3. I take a number of low dose detox for heavy metals as well. I'm looking forward to more research on fatty 15. I use some grass fed butter and ghee in hopes of improving cellular function.
840mg per day as in total fish oil, epa or dha? (Approx 9 mins)
Total (fish) oil. They've not said if that refers to algae based oils, but you can assume it's the same.
i have the same question!
Whatever other issues the study has: most omega-3 supplements are rancid; they are oxidized. Most are not oxidation protected, hence they are just costly poison pills. Anyway, the issue isn’t low intake of omega-3s, the issue is high intake of omega-6s.
The critics argue that we should cut back on our intake of omega-6 fats to improve the ratio of omega-3 to omega-6s. Hogwash, says the American Heart Association (AHA). In a science advisory that was two years in the making, nine independent researchers from around the country, including three from Harvard, say that data from dozens of studies support the cardiovascular benefits of eating omega-6 fats (Circulation, Feb. 17, 2009). "Omega-6 fats are not only safe but they are also beneficial for the heart and circulation," says advisory coauthor Dr. Dariush Mozaffarian, an assistant professor of medicine at Harvard-affiliated Brigham and Women's Hospital.
@@tomgoff7887 Nice appeal to authority. :D A bit like American diabetes association supporting high carb diets for type-2 diabetes.
In your own words: why and how did they come to the conclusion that omega-6:s are beneficial for cardiovascular health? Could it perhaps have everything to do with the many years ago debunked LDL-hypothesis? Most likely.
@@Divinefapper You clearly don't understand that referring to the AHA's scientific report summarising and citing the evidence is not an "appeal to authority". Just as you clearly don't understand the scientific evidence behind the ADA's recommendations.
@@DivinefapperThey all got kickbacks from the seed oil industry
@@DivinefapperCiting a study in detail is an authority fallacy nowadays. Oh dear.
You know he gave you enough information for you to read the study yourself, right?
I just started taking Vegan Omega-3 Veggie Gels; DHA 450 mg, DPA 70 mg, two capsules per day. At age 58, I was curious if it would help improve heart and brain related issues. After a month of use, I am still having trouble finding those car keys; working on stubborn BP 145/85, and dealing with jiggling love handles... so why the vegan experiment? Maybe plants can reverse my years of overindulgence... learning from your videos, thank you.
I'm pretty sure this study mentioned that the risk showed up for women and not with men.
Some years ago they linked Omega 3 fish oil even with prostate cancer . Taurine alarming research is out now 😢
What does Taurine have to do with this?
What is the problem with taurine, which study is that?
What was the source of Omega 3s ?
Ask the source of the funding - Bill Gates.
@@simonwiltshire7089 stop
I've been searching for a table, guide or document which has optimal blood result markers to aim for. Obviously "nirmal" ranges are easily available. But optimal ranges aren't. I hope you can help sign post me or cover in a future video
The iron maiden line was so funny... I still remember a friend of mine got an A in their poetry assignment when they submitted an iron maiden song. Lolwhut
What about flaxseed omega 3, it’s not fish oil?
It's also mostly not converted into the relevant omega-3. Your body needs the omega-3s that come from fish/algae. The problem this study is highlighting is not fish oil per se, but what is possibly an excessive amount.
I swear the answer to every research question is: "It depends"
Context is everything. That is probably why we have qualified doctors as they can make finer judgements than me.
You know why I'm angry? Because no one studies profoundly the effects of those food additives that are consumed on a daily basis, and the other types of herbicides and free amino acids (Lizine)that are given to animals, (and eaten by us) ruining their immune systems, digestive system etc. The abundance of glyphosates in our bread causes infertility, IBS, high triglycerides, and more. Yet, another study comes out claiming that Omega-3s are not that beneficial, even though it has been demonstrated over many years, that in Eskimo populations there are no heart diseases whatsoever due to the high consumption of fish rich in Omega-3s. Now they want to sell GMO corn oil( rich in glyphosates) , of course... damn.
You're conflating fish with Eskimos having no heart disease. So were the original researchers. You're exposed to seed oils and other highly processed foods that they aren't. Their lifestyles are highly active and very cold, where cold water is proven to be restorative. It's just not as simple as "fish bits".
The study also did not look at the quality of the supplements taken. Many cheaply manufactured fish oil supplements are essentially rancid before the cap is even removed.
Irrelevant since the cause of the problem here is the omega 3 itself. The fact that this result has been found with pharmaceutical grade fish oil as well adequately demonstrates that the changes in the cell membrane that result from too much omega 3 are the likely cause. I don't know why so many people are so desperate to create spurious causes like rancidity. Just stick to sensible intakes of these fatty acids.
PHYSIONIC, you should start with a simple summary of the results - answer the main question - is the study right or wrong? Then after that, explain all the studies for the few people who want to understand all the details. Most people don’t have time to study all that - they’d rather trust someone like you, to read the studies for us and give us the answers.
What is the opinion on algae based Omega 3 and DHA ? I use a iwi life brand for both.
Curious if the study corrected for the possibility the fish oil was oxidized. The proportion of people with negative consequences could match the proportion of oxidized fish oil on the market.
This would also be the case for non animal based omega 3 supplements as well
Any evidence that oxidation can have this effect on the heart rhythm? Why would we need to introduce an oxidation hypothesis when the presence of omega 3s adequately explains the increased risk of atrial fibrillation? In fact we'd expect oxidation to lower the likelihood of atrial fibrillation, because it reduces the omega 3 content.
How about people who care about their health by taking supplements just check their heart more often, so they notice and report atrial fibrillation more?
I would like them to report the brand of fish oil when fibrillation begins.
That's something that would interest me.