Enzymes | Mechanism of enzymes | Lock and key model | induce Model | NBF | federal board | FBISE

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  • Опубликовано: 18 окт 2024
  • Lock and Key Model:
    Description: The Lock and Key model proposes that enzymes have a rigid, pre-formed active site that perfectly complements the shape of the substrate molecule.
    Key points:
    Enzyme active site is shaped like a lock
    Substrate molecule is shaped like a key
    Substrate binds to active site with high specificity
    Enzyme-substrate complex forms, facilitating catalysis
    Limitations:
    Does not account for flexibility in enzyme structure
    Does not explain how enzymes can bind to multiple substrates
    Induced Fit Model:
    Description: The Induced Fit model proposes that enzymes have a flexible active site that changes shape to accommodate the substrate molecule.
    Key points:
    Enzyme active site is flexible and dynamic
    Substrate binding causes conformational change in active site
    Active site shapes itself to fit the substrate molecule
    Enzyme-substrate complex forms, facilitating catalysis
    Advantages:
    Accounts for flexibility in enzyme structure
    Explains how enzymes can bind to multiple substrates
    Provides a more accurate representation of enzyme-substrate interactions
    Note: The Induced Fit model is a more modern and widely accepted explanation of enzyme action.
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