Mechanism of Chymotrypsin and Catalytic Triad

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  • Опубликовано: 4 ноя 2024

Комментарии • 246

  • @mohammadhussaini2815
    @mohammadhussaini2815 5 лет назад +57

    I feel like I should pay you my tuition fees instead of paying it to my university, so sad can't do it. thanks mate helped safe my life from biochem

  • @kylecl12
    @kylecl12 9 лет назад +256

    Hey just wanted to say that I love all of your videos. Currently in Biochemistry, and this is helping me out so much. You go more in depth than my professor but at the same time it is much easier to grasp! Thank you

    • @AKLECTURES
      @AKLECTURES  9 лет назад +40

      +kyle clark Hey Kyle, thats wonderful to hear! Study hard and youll love biochem, its an awesome subject! :)

    • @thefenerbahcesk4156
      @thefenerbahcesk4156 6 лет назад

      Did you guys have to memorize the whole mechanism?

    • @agiemylona2347
      @agiemylona2347 5 лет назад +7

      @@thefenerbahcesk4156 I am doing a Biochemistry degree and we were told we have to know the mechanism. The key point is to understand the principles underneath (how it works, why it works that way, understand the flow of electrons) it so that you can be able to "solve" other mechanisms as well. Hope this is helpful :)

    • @debbyralph6136
      @debbyralph6136 3 года назад +2

      What degree do you have now?

  • @jemiller8678
    @jemiller8678 9 лет назад +109

    You've succeeded in making a semester where I'm taking PathMicro, Organic, AND Biochem seem just a little bit clearer. I can't explain how much sleep your videos have saved me and I can never thank you enough for the clarity your lecture bring.
    Seriously.
    You're awesome.

  • @Nitro0xide
    @Nitro0xide 9 лет назад +74

    You are better than 99% of profs in the world. Thanks a lot for your videos!!

  • @kumquats2842
    @kumquats2842 3 года назад +7

    a 15 minute video did a better job of explaining this than a 2 hour lecture from my professor. bless you my dude

  • @ro1882
    @ro1882 9 лет назад +15

    hands down, you deserve a trophy for teaching this! Thank you!
    sincerely, from a student attending an overly overrated high ranking university!

  • @No2clarinet
    @No2clarinet 4 года назад +8

    You are legitimately saving my grade right now! All of your videos are perfectly balanced with diagrams and knowledge. You don't overload us with minor details. Very well done!! Thank you so much

  • @JBrimBloodG
    @JBrimBloodG 7 лет назад +57

    my favorite educational 1.25x speed channel

    • @dovedon5583
      @dovedon5583 4 года назад

      ...lolz... I guess I'm not alone.

  • @mnoori100
    @mnoori100 9 лет назад +12

    I literally watched 5 other videos and read the text on this topic only to get more confused than I started. THANK YOU!!!! I finally understand it clearly. By far the best explanation found!! You're always the best :)

    • @AKLECTURES
      @AKLECTURES  9 лет назад +5

      Bella Thats wonderful to hear! thanks for watching ! :)

  • @nerdalert1496
    @nerdalert1496 8 лет назад +16

    All of your videos are so helpful. Thank you so much for making them! You're saving many biochem students!

  • @Abby-in6tk
    @Abby-in6tk 11 месяцев назад

    You sir have officially entered my list of "people I'd MUCH rather pay my tuition to". When my prof went over this, I was so overwhelmed. Now I at least feel I know the basics of what's going on here. If I survive biochem it's probably gonna be all thanks to you. Thank you so much for these videos 💙

  • @kennethbutler9164
    @kennethbutler9164 5 лет назад +1

    My dude. You explain things so well. So fluid. Thank you!!

  • @yuvalmohl8408
    @yuvalmohl8408 Год назад

    you're most definatley the best prof ever, you made it so much simpler than what I initialy thought when I saw it. thank you so so much!

  • @Freshtodeath2000
    @Freshtodeath2000 9 лет назад

    I've watched a lot of lectures on the internet, read a lot of books in my lifetime. This is one of the best explanations I have ever seen in any subject, clearly spoken, not many mistakes and summarizes the "big picture" so at the end of the day you are taking home the right message.
    subscribing

    • @AKLECTURES
      @AKLECTURES  9 лет назад

      teflon don thanks! I really appreciate that ! :)

  • @adesuwaomede7803
    @adesuwaomede7803 5 лет назад

    Hands down the best mechanism explanation video I have ever watched. Thank you.

  • @vietkutie001
    @vietkutie001 8 лет назад +1

    OMG, just saved me!!! Been trying to find other resources to explain this process for weeks! Thanks so much!

  • @genthomasset8377
    @genthomasset8377 6 лет назад

    Please come teach at my school. At this rate, you're the reason why I passed / did well in orgo, immunology and hopefully now biochemistry. So helpful as always & thanks a million from a desperate college student.

  • @rythammanhasfilms
    @rythammanhasfilms 3 года назад

    Amazing Explanation, I am from India and don't have any trouble understanding your lectures. The clarity and depth with which you explain, hats off.

  • @meganlehr7632
    @meganlehr7632 Год назад +1

    i owe you my life

  • @user-gi6mh2dn7b
    @user-gi6mh2dn7b 8 лет назад +2

    I hope you are interacting with college students (be it TA, prof, etc.) because your explanations are always concise and clear! You've helped me with my general biochem course on a level no one else has ever! I appreciate your work.

    • @AKLECTURES
      @AKLECTURES  8 лет назад +2

      +R thanks, I appreciate that! I am doing something like that :)

  • @danielpie2046
    @danielpie2046 7 лет назад +1

    Explaining mechanisms does not get better than this. Thank you so so much!!!

  • @miminramzi6456
    @miminramzi6456 8 лет назад

    thank you for existing! i have exam this evening and i can't understand a single step in my notes but you save my life. thank you so much!

  • @Am-ug9np
    @Am-ug9np 7 лет назад +1

    My teacher doesn't lecture, just tells us to teach ourselves out of the book then quizzes us for the entire class period. I need someone to explain things to me so this is literally saving me 👏 Thank you so much

  • @bv8560
    @bv8560 8 лет назад

    Hey just wanted to agree with everyone else and send my deepest thanks to you! This was three exam questions & I can confidently say I don't know what I would do without this video along with your other biochem videos. You rock!

  • @sandraz3466
    @sandraz3466 9 лет назад +5

    I wish I had seen your videos earlier when I was taking some of my other hard science courses! I am taking biochemistry now and doing MCAT prep and you make the concepts so clear. Thank you so much for these videos and keep on spreading your knowledge! :)

    • @shaktiramnath6694
      @shaktiramnath6694 3 года назад +3

      hey girl hope youre a successful doctor/med student right now

  • @LifewithAmairanny
    @LifewithAmairanny 22 дня назад

    This was a true masterpiece, if I've ever seen one

  • @daphnesilvertand
    @daphnesilvertand 2 года назад

    I watched this a while ago and did understand then I forgot and I could not manage on my own for over an hour, then I watch this movie and in 10 min it is clear again! Amazing thanks!

  • @violetlavi2207
    @violetlavi2207 2 года назад

    Thank you for simplifying such a complicated mechanism!

  • @chueklamable
    @chueklamable 9 лет назад +3

    much clearer than my notes~~~ thanks for your effort

  • @amsd5780
    @amsd5780 2 года назад +2

    Thank you so much, so quick and clear ! It made this processus go from really scary to actually very interesting :)

  • @HardmanTech
    @HardmanTech 9 лет назад

    First video in hm... 100 videos that I see and now I understand, then thank you bro!
    From Brazil.

  • @magkann
    @magkann 7 лет назад

    you are A MILLION TIMES better at teaching than my professor!! I LOVE YOUR VIDEOS BLESS YOUR SOUL

  • @niralivachhani7560
    @niralivachhani7560 7 лет назад +1

    Your videos are awesome! I struggled with biochemistry but your videos are really helping me, it makes easier for me to understand the concepts.

  • @hellojmister
    @hellojmister 8 лет назад

    Amazing the clarity with which you explained this - It really helps that you explain each step and why it happens instead of just describing what happens. I can't explain how poorly and confusingly my lecturer taught this.

  • @DR-kh9bl
    @DR-kh9bl 5 лет назад

    thank you so much, what a life saver. this mechanism looked impossible to understand, but not anymore thank youuuuu.

  • @thanasisgiantzaklidis5497
    @thanasisgiantzaklidis5497 2 года назад

    Once again, incredible and 110% explainatory video, I wish you were my university teacher!!!

  • @sakshisharma3297
    @sakshisharma3297 5 лет назад

    You provide the best explanations on the most confusing topics... Thankyou so much for making learning easy.... Keep doing the good work... You really are being highly blessed by the students that get your help through the lecture.... Keep making videos on every little topic related to biochemistry and biotechnology....

  • @clarissagilmore
    @clarissagilmore 5 лет назад

    you will probably be the reason I pass Biochem, I love you.

  • @Jade-sv2wp
    @Jade-sv2wp Год назад

    My gosh this helped me understand this mechanism so much better thank you so much TT!!!

  • @thynguyen911
    @thynguyen911 7 лет назад +1

    I can't thank you enough for making these biochemistry videos! You explain everything much better than my professor! THANK YOU (:

  • @deemaalobaidi4630
    @deemaalobaidi4630 4 года назад

    Your teaching style is amazing ...thank you!

  • @barbxrox
    @barbxrox 5 лет назад

    U ARE AN ANGEL OF A HUMAN BEING!!!!! THANK YOU FOR DOING WHAT MY PROFESSOR COULD NEVER! school is a scam kids

  • @IqraLiaqatspbsbt
    @IqraLiaqatspbsbt 2 года назад

    Very well explained. It is very helpful thanks alot. May you prosper. Ameen

  • @robertgrassi6285
    @robertgrassi6285 8 лет назад

    Wow, bravo. Very clear, very comprehensive, very neat.

  • @lauradumo
    @lauradumo 7 лет назад

    Seriously, I love you!I don't even have to go to class anymore

  • @lyanadhamirah7381
    @lyanadhamirah7381 4 года назад

    so glad I found your channel. Very well explained.Thank you so much!!

  • @minervagao7223
    @minervagao7223 2 года назад

    Bro you save my life!!! Life saver!

  • @tomiowoeye9407
    @tomiowoeye9407 5 лет назад

    You make things make so much sense

  • @DR-kh9bl
    @DR-kh9bl 5 лет назад

    Thank you again I will watch this vid many times, even though I understood it from the first time, but you explain so beautifully and clear that makes me want to watch it again. it is so fun when u understand. thank you

  • @geraldinelee9230
    @geraldinelee9230 4 года назад

    Best educational video, plus watching ur videos feels like riding a roller coaster phew

  • @tahirtantary7438
    @tahirtantary7438 2 года назад

    Best ...Lots of Love from Kashmir...

  • @konvicteddestruction6183
    @konvicteddestruction6183 3 года назад

    Thanks a lot for your videos! Its really helpful for our curriculum.

  • @chabby_joe
    @chabby_joe 9 лет назад

    You are a boss!!! I've got my biochemistry exam tomorrow and I feel really ready now thanks to you!!!! Keep up the amazing work!!!

    • @AKLECTURES
      @AKLECTURES  9 лет назад +1

      Joe Charbine Thanks Joe, best of luck on your biochem exam! let me know how it goes.

  • @notagunexpert8117
    @notagunexpert8117 9 лет назад

    You are saving me in Biochem right now! Thank you

  • @qraxulz4376
    @qraxulz4376 2 года назад

    Zain Nassar loves your videos man ong

  • @gabrielatheismarchan7059
    @gabrielatheismarchan7059 3 года назад

    geat explanation. Really helped me to understand better

  • @anshukamboj8615
    @anshukamboj8615 4 года назад

    Thanku so much it helps me alot. Love from india

  • @hankhill8044
    @hankhill8044 9 лет назад +28

    In step 3 you should have an amine group leaving and deprotonating the histidine, not an amide.

    • @user-gi6mh2dn7b
      @user-gi6mh2dn7b 8 лет назад +1

      +Hank Hill I was confused about this for a second. I'm glad I wasn't the only one who noticed! He did a fantastic job otherwise

    • @thefenerbahcesk4156
      @thefenerbahcesk4156 6 лет назад

      Amine vs Amide what's the difference?

  • @AriJeru
    @AriJeru 8 лет назад

    This is so fantastic. Please keep it up, these are so so helpful

  • @skittless3949
    @skittless3949 9 лет назад

    Great work! Clear, concise, and very helpful! Definitely subscribed and will spread the word about your amazing videos!

  • @afaq289
    @afaq289 6 лет назад

    Thank you so much for all videos you are doing. help me a lot in my biochemistry class.

  • @edene7354
    @edene7354 Месяц назад

    Thank you so much for this! It helped me so much!

  • @tsewangladol8514
    @tsewangladol8514 8 лет назад

    if u were my professor of biochem class,i would hav topped the class..u r an amazing teacher.thanku for the great videos

  • @josejr7278
    @josejr7278 3 года назад +1

    If you speed up the video at 1.75x this dude is loudly and aggressively teaching you

  • @dejanvukovic9763
    @dejanvukovic9763 Год назад

    This is the best explanation

  • @kikicucci1910
    @kikicucci1910 5 лет назад +1

    thank you so much so helpful for medical school

  • @Barbie4wido
    @Barbie4wido 9 лет назад

    you are the best. awsome lectures.

  • @kennethbutler9164
    @kennethbutler9164 4 года назад

    Awesome job man. I wish I could give more than one like on this video

  • @zarawarsi
    @zarawarsi 2 месяца назад

    Awsome lecture in just 12 mint❤

  • @sarahmoselyyy
    @sarahmoselyyy 7 лет назад

    great explanation!! way better than my profs

  • @동쪽-z5v
    @동쪽-z5v 9 лет назад

    respecting your teaching! thank you for your simple explanation.

  • @kp9269
    @kp9269 Год назад

    Amazing showstopping brilliant

  • @NguyenPham-fg7gi
    @NguyenPham-fg7gi 3 года назад

    YOU MAKE SO MUCH MORE SENSE THAN MY PROFESSOR =(((( THANK YOU SO SO SO MUCH

  • @adityasiddharth6782
    @adityasiddharth6782 9 лет назад

    That was a beautiful explanation...Love yours vids...Keep up the good work

  • @Jay-wy8uv
    @Jay-wy8uv 9 лет назад +1

    nice lecture. easily understood! thx

    • @AKLECTURES
      @AKLECTURES  9 лет назад

      안희태 you're welcome! :) thanks for watching

  • @אינהפיגלצוק
    @אינהפיגלצוק 4 года назад

    Best lecture ever

  • @kr7638
    @kr7638 8 лет назад +58

    I love you.

  • @theranaxo
    @theranaxo 7 лет назад

    Your videos are saving me in Biochemistry!
    I'm sure my whole class watches your videos haha, I wish you were my professor :(
    Thank you so much!!!!!

  • @fabolous989
    @fabolous989 7 лет назад +1

    Fantastic explanation. Thank you!!

  • @nathaliekirshman3335
    @nathaliekirshman3335 8 лет назад

    Thank you, this was so clear and easy to understand!

  • @emmaforrester7677
    @emmaforrester7677 4 года назад

    Your videos honestly are saving my biochemistry grade. These videos actually make me like the subject! Thank you so much!

  • @oldaccountm3477
    @oldaccountm3477 6 лет назад

    Thank you, this was very clear and helpful.

  • @kareem9102
    @kareem9102 8 лет назад

    Wow. That was amazing explanation. Thank you very much.

  • @nxph2108
    @nxph2108 7 лет назад

    Sir you have been saving my ass every time i get serious the day before the exam. God bless u

  • @mirizapisotsky7778
    @mirizapisotsky7778 Год назад

    amazing video! helped me a lot! thanks

  • @Larcen157
    @Larcen157 8 лет назад

    great explanation ! thanks for the hard work.

  • @skittless3949
    @skittless3949 9 лет назад +13

    5:04, you said asparte uses its full positive charge, I think you meant negative.

  • @rimkenan4654
    @rimkenan4654 8 лет назад

    Thank you you are saving my life!

  • @valeriewarkins3704
    @valeriewarkins3704 4 года назад

    Wow this was so clear, thank you!

  • @bitasadeghi7995
    @bitasadeghi7995 2 года назад

    I feel like you are going to win a Nobel prize one day

  • @xueyuzhang1849
    @xueyuzhang1849 6 лет назад

    you saved my life

  • @tejasshinde3006
    @tejasshinde3006 6 лет назад

    Awesome explanation

  • @hamedhosseini4938
    @hamedhosseini4938 7 лет назад

    Dude, You are legend. I wish you were still active and had your channel alive so you could make more videos. It's shame that you gone, nevertheless wish you all the best with your career.

  • @haneefakram3001
    @haneefakram3001 7 лет назад

    your videos are too good

  • @SaraiGarage
    @SaraiGarage 5 лет назад

    Amazing Video. Thank you 🙌🏾

  • @aunmurtaza9964
    @aunmurtaza9964 9 лет назад

    Amazing explanation, u know how to teach and explain. You should have also mentioned the Pka of Histidine and how it is increased making it a strong base.

  • @dordor42
    @dordor42 7 лет назад

    Amazing lecture! you helped me alot. thank you!

  • @garciabreezy
    @garciabreezy 8 лет назад

    Thanks a lot, it was a great help for me your explanation!

  • @billoryraja
    @billoryraja 7 лет назад +1

    man you're the best

  • @sharonsequeira8080
    @sharonsequeira8080 8 лет назад

    This was extremely helpful! Thank you so much!!