Hypoxic pulmonary vasoconstriction | Circulatory system physiology | NCLEX-RN | Khan Academy
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- Опубликовано: 27 ноя 2012
- Watch how blood gets diverted away from alveoli with low oxygen levels. Rishi is a pediatric infectious disease physician and works at Khan Academy. Created by Rishi Desai.
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Basically:you are shunting blood from an area (alveoli) of low oxygenation to an area of higher oxygenation, so that you increase gas exchange in an attempt to maintain good oxygen saturation.
More simply: Take blood from where there is no oxygen to an area where the blood can pick up more oxygen and give it to the rest of the body!
More Simpatico:Move Blood from where there is no O2 to an O2 rich area!
What is both lungs were oxygen deficit ? Will HPV still happen? If yes, where will it shunt the blood to ?
Thank you for this straight to the point explanation!
@@florence6654
it just like if both kidneys death = failure of kidneys....
so what happen to the lung lack of blood flow and oxygen? Ischemia?
Excellent explanation and very relaxing, comforting voice.
Found it! See a paper by Wang et al (2012). In a nutshell: Hypoxia is thought to inhibit K+ channels of capillary membranes to cause depolarisation. This depolarisation is propagated via connexin-40 to arteriole membranes. There, voltage-dependent calcium channels open and caclium influx results leading to the constriction of arteriole smooth muscle.
Explained it so well, great job!
perfect thanks
thank you sooo much. you just save my grade.
This is perfect!!
Great video! Thanks
This is the best explination i heard about this topic 👏 ❤
Great explanation, used this to compare/contrast with response to hepatopulmonary syndrome vasodilation... Two reactions happening in the same lung.
-Brad RRT
Thankyou ❤️ very well explained.
good expline :)
and it is chronically leads to right side heart failure . Because of the hypertension of pulmonary vessels and cor pulmonale develops
Only lungs, in other tissues low PO2 induce vasodilation.
Thank you 🙏
so can I use health and medicine videos to prepare fro MCAT ??
Thank you very much
you are the best, i love you keep going
What a great explanation, THANKS A LOT!!
Awesome
Superb!
Great video, but I could not help thinking of Jack Sparrow and his "peanut,mine!" moments in the 3rd pirate movie :)
Man, you just rulled it! Thanks a lot!!
What is the treatment for hypoxic vasoconstriction.?
What is the signal? In exams we need to name stuff like that!
Why not vasodialatation occurs as in systemic hypoxia vasodialatation occurs?
Does this only happens for arterioles in the lungs or in other organs as well?
Only the lungs
How fast the hypoxic pulmonary vasoconstriction occurs after an acute bronchial obstruction?
Depending on what you read when PaO2 falls below 70