The four horsemen of death and how to prevent them

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  • Опубликовано: 8 сен 2024
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    Watch the full episode: • 311 ‒ Longevity 101: a...
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    This clip is from episode #311 ‒ Longevity 101: a foundational guide to Peter's frameworks for longevity
    In this clip, they discuss:
    - What are the four horesemen of death?
    - How prevalent are each of the four horsemen of death?
    - Tactics for preventing each of the chronic disease categories?
    - And more
    --------
    About:
    The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
    Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
    Learn more: peterattiamd.com
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Комментарии • 81

  • @ilkhamfy
    @ilkhamfy Месяц назад +20

    🎯 Key points for quick navigation:
    00:00:00 *🚑 Cardiovascular Disease Prevention*
    - Cardiovascular diseases like atherosclerosis are heavily influenced by genetic and environmental factors.
    - Prevention focuses on reducing apolipoprotein B (apoB) levels, protecting endothelial health, and managing inflammation.
    07:46 *🩸 Cancer Prevention*
    - Cancer prevention involves understanding genetic predispositions like BRCA mutations and environmental triggers such as smoking and obesity.
    - Early and aggressive screening strategies are controversial but considered important in high-risk individuals.
    14:35 *🧠 Neurodegenerative Disease Prevention*
    - Preventing neurodegenerative diseases, like Alzheimer's, involves maintaining cardiovascular health through interventions such as exercise and metabolic management.
    - Cognitive and movement reserves play crucial roles in resilience against these diseases.

    • @tf-ok
      @tf-ok Месяц назад

      I am the 4th horseman.

  • @K4R3N
    @K4R3N Месяц назад +20

    His book (which i own and have recommended to many) summarized in 20 minutes (or 15mins at 2x playback speed!)

    • @NicholasOdinson
      @NicholasOdinson Месяц назад +6

      Wouldn’t 2x speed be 10min? 🤔
      Agreed, I’ve given his book to probably a dozen people.

    • @K4R3N
      @K4R3N Месяц назад +4

      @@NicholasOdinson damn I must getting Alzheimer's already!😂

  • @monicabroniecki7624
    @monicabroniecki7624 Месяц назад +4

    Very considered approach to questions by Nick, and then very clear responses by Peter. Works well.

  • @Joy80JJ
    @Joy80JJ Месяц назад +2

    Live your life with what makes your body feel & work well to sustain life as long as possible to avoid a medical intervention.

  • @K4R3N
    @K4R3N Месяц назад +5

    17:55 "virtually no therapeutic options" 😭😭☠️

    • @donaldwindland
      @donaldwindland Месяц назад +1

      If you can catch it soon enough, you can slow it down, but to cure/heal... yeah nah you up the creek on that one fam.

    • @K4R3N
      @K4R3N Месяц назад

      @@donaldwindland yeah man, even my neurologist friend admitted they got nothing more than some "experimental" drugs.

    • @SamShank175
      @SamShank175 21 день назад +1

      Look into Dr Dale Bredesen's work on Alzheimer's.

  • @laurentgaildraud9164
    @laurentgaildraud9164 Месяц назад +9

    I like this statistical approach, far from certainties and religion.

    • @K4R3N
      @K4R3N Месяц назад +3

      God doesn't care about my arteries

  • @gibby5335
    @gibby5335 Месяц назад +1

    Someone get me on this podcast. Inflammation and cancer is much easier to unpack than everyone thinks

  • @RonSwansonIsMyGod
    @RonSwansonIsMyGod Месяц назад +13

    The horsemen are drawing nearer
    On leather steeds they ride
    They've come to take your life
    On through the dead of night
    With the four horsemen ride
    Or choose your fate and die
    Aw yeah, yeah...

    • @OrlandoAponte
      @OrlandoAponte Месяц назад

      My favorite Metallica song

    • @GamerNxUSN
      @GamerNxUSN 23 дня назад

      Whoever thought you'd be better
      At turning a screw than me
      I do it for my life
      Made my drive shaft crank
      Made my pistons bulge
      Made my ball bearing melt from the heat
      Oh yeah yeah.....oh sorry.... wrong song.....

  • @Case10y
    @Case10y Месяц назад +1

    In regards to diet have you seen an increase in cancer risk with the increase in processed foods? Such as aspartame, high fructose corn syrup, food coloring.....

    • @Great_PatBingsoo
      @Great_PatBingsoo Месяц назад

      How do you isolate these from other factors, even in rats? Results will be equivocal at best…

  • @nickst0ne
    @nickst0ne Месяц назад

    Thanks for the insight on atherosclerosis.
    In one of Chris Williamson's podcast this year, a female guest mentioned that Omega-3 supplementation can have a positive effect on longevity with an effect size equal to the negative effects of smoking one pack a day.
    I'd love to hear your input on this.

    • @SamShank175
      @SamShank175 21 день назад

      Rhonda Patrick talks a lot about Omega 3s.

  • @mellink14
    @mellink14 Месяц назад +2

    Diagnosed with a slower developing leukemia (CLL) 9 months ago. Wish I could get an edge how to keep it from advancing as much as possibly. I have always had a healthy lifestyle. Searching for the most optimal diet. Any recommendations?

    • @hillsofwi
      @hillsofwi Месяц назад +1

      Some claim to have had success with fasting. You might look into that. Best wishes to you.

    • @mellink14
      @mellink14 Месяц назад

      @@hillsofwi I'll research that. Thanks!

  • @georgeyoung2123
    @georgeyoung2123 Месяц назад

    There is an agent to better manage endothelial inflammation and that is low dose colchicine. Review the Lo-Do-Co studies. Maybe low dose colchicine should be a primary preventive therapeutic in high risk individuals.

  • @2023Red
    @2023Red Месяц назад +1

    Four horseman. I wonder if there is fifth called nanoplastics.

  • @KJSvitko
    @KJSvitko Месяц назад +4

    You are what you eat. Your diet impacts your health.
    Lower stress, reduce obesity, get enough sleep and more exercise are key to a healthy life.
    Obesity in children and adults is rising across the world.
    Fast food and sugary drinks including fruit juices are contributing to the problem of poor health and obesity.
    Eat a healthy plant based diet and exercise regularly.
    Reduce or ELIMINATE cows milk, eggs, cheese and meat. Eat more salad greens, beans, fruit and vegetables. Eliminate fast food, snacks like cookies, cakes, chips, and sugary drinks and juices.
    Every adult and child should own a bicycle and ride it regularly.
    Regular exercise will help you sleep better. Yoga is a great stress reducer.
    Obesity is all too common today. Get off the couch. Get off the phone, ipad or video game.
    A variety of stretching and other exercises help with increased mobility.
    Ride to work, ride to school, ride for fun.
    Every city should be a bicycle city.
    Speak up for bicycles in your community

  • @Cathy-xi8cb
    @Cathy-xi8cb Месяц назад

    I have treated too many children who die of disease. Bad luck is happening to many people, every day.

  • @user-ip8zo7wn6d
    @user-ip8zo7wn6d Месяц назад

    Air pollution in with smoking,or oxidative damage? Like your presentations, Peace

  • @naumanshah4764
    @naumanshah4764 Месяц назад

    That’s brilliant

  • @AmanKumarSharma-de7ft
    @AmanKumarSharma-de7ft Месяц назад

    What I don’t understand is he talks about how you should never over nutrition which is bad matabolically and he also talks about putting more muscle mass as soon as possible since thats your currency and it stats depleting once uou are over 30 and this requires you to be in a calarie surplus and thats the difference between theoretically talking about it and practically implementing it.

  • @cookinthekitchen
    @cookinthekitchen Месяц назад

    I am still confused about if hyperinsulinemia is the cause of insulin resistance and if this is solely caused by elevated blood sugars or if there is another major reason for this condition.

    • @EVanDoren
      @EVanDoren Месяц назад +1

      The cause of insulin resistance is intracellular fat. Look up the Shulman episode.

    • @chriskozak7356
      @chriskozak7356 Месяц назад

      Excess PUFAs from seed oils and added sugar foods in combination. IE Ultra Processed foods, cereal, refined grains etc.

    • @EVanDoren
      @EVanDoren Месяц назад

      @@chriskozak7356 Bullshit, it's saturated fat

    • @chriskozak7356
      @chriskozak7356 Месяц назад

      @EVanDoren definitely not bullshit. Fat coats the cells, causing excess sugar to not be processed. It's both, but especially fat.

    • @EVanDoren
      @EVanDoren Месяц назад

      @@chriskozak7356 🤦🏻🤦🏻🤦🏻 There is no such thing as "fat coats the cells". It's very specific fat metabolites, diacylglycerol containing saturated fatty acids, which can dock on the IRS-1 inside the cell, thus inhibiting the downstream signal transduction from the insulin receptor.
      Please don't elaborate on anything if you don't have a precise understanding of how things work on the molecular level.

  • @KilliMilliMeter
    @KilliMilliMeter Месяц назад

    It's likely that research or clinical trials were conducted with people who represent only 16% of the world population. Q: Are these findings specific to North American population (i.e., USA and Canada)?

  • @KJSvitko
    @KJSvitko Месяц назад

    Processed food manufacturers need to hear from consumers that less ADDED chemicals, sugar, oil and salt is wanted in their food products.
    Why is there so much ADDED sugar in everything, even bread. That's just crazy
    Email, text, tweet or phone your favorite producer of poison and let them know consumers want less salt, oils and sugars in their products.
    Let their customer service department know that all the extra added salt, oil and sugar is not necessary or desired and is causing health issues.
    Reduce or eliminate highly processed food from your diet if you can.

    • @SamShank175
      @SamShank175 21 день назад

      They only care about profits, they ensure profits with addictiveness. All the sugar and salt is what's addictive. They literally do experiments to test the Bliss Point, that's the amount of sugar and salt that makes your brain light up. They won't take the crap out, they just rename it, that's why there's a million names for sugar and "natural flavors", that are anything but natural when they're done with them.

  • @tjanderson6162
    @tjanderson6162 Месяц назад

    I'm confused. Doesn't exercise also cause increased inflation and growth factors? Would exercise then increase cancer, like for obesity?

    • @bc1033
      @bc1033 Месяц назад +5

      The key with exercise is it is an acute transient stress. Allowing for rest, recovery and adaption.
      These diseases/pathologies are chronic and constantly stressing you. While you're awake while you're asleep all the time.

    • @Tritiuminducedfusion
      @Tritiuminducedfusion Месяц назад +1

      Exercise is literally a cure-all. You sound like a lazy person, trying to justify being lazy. 🙄

  • @AndrewPawley11
    @AndrewPawley11 Месяц назад +10

    A whole food plant based diet addresses each of these risks directly.

    • @ShastaTodd
      @ShastaTodd Месяц назад +1

      YEP, low glycemic/ keto vegetarian since 1977.
      I am 68, have a CAC of 2, RHR of 45, BP 120/60 and am super healthy and fit!

    • @AndrewPawley11
      @AndrewPawley11 Месяц назад +2

      @@ShastaTodd An RHR of 45 at 68 is an achievement worthy of note. Great job!

    • @KJSvitko
      @KJSvitko Месяц назад +1

      Go vegan for your health, whole food plant based.
      Go vegan for the animals. Go vegan for the planet. Go vegan and be healthier and happier.
      A lower risk of heart disease and cancer for you and a better planet for everyone, human and animals.
      Eating healthy is not a diet it is a healthy life style.
      Go out and look around. The vast majority of people you see are obese or al least over weight.
      People do not need to be fat shamed BUT being over weight is not healthy and leads to a host of illnesses.
      When you look around you can see all the unhealthy people without taking a blood test or a fitness test
      "NORMAL" for the average American is "UNHEALTHY" The health of society is in decline.

    • @EVanDoren
      @EVanDoren Месяц назад +1

      Yes. 💯

  • @debbiesc.5957
    @debbiesc.5957 Месяц назад

    Is eating fruit seeds healthy?

  • @chrischris8481
    @chrischris8481 Месяц назад

    How does one lower Apo B?

    • @EVanDoren
      @EVanDoren Месяц назад +1

      Plant-based diet, nattokinase, barberries, amla, exercise

    • @SamShank175
      @SamShank175 21 день назад

      It's definitely not a plant based diet, those tend to come with other health issues. Look up vegan diet and thyroid, osteoporosis, etc.
      A healthy diet should be good for the whole body. I guarantee Peter isn't recommending plant based to any of his patients.
      They want you to believe that cholesterol is settled science, but they really don't know.
      Look up the work of Dave Feldman.
      Focus on what causes damage to the endothelial membranes, diabetes, metabolic syndrome, high blood pressure, smoking, etc.
      These are also the things that work on inflammation.

    • @rezedent9104
      @rezedent9104 19 дней назад

      Cut saturated fat too.

    • @EVanDoren
      @EVanDoren 19 дней назад

      Green tee, beta-glucans in the morning (oats, barley, mushrooms, nutritional yeast)

  • @swamphawk6227
    @swamphawk6227 Месяц назад +6

    War, Famine, Pestilence, and Death.

  • @oldnatty61
    @oldnatty61 Месяц назад +2

    There's only one horseman of death now days. That's this over examination and complication of something that was once simple and straightforward.

  • @Nick-gg6tg
    @Nick-gg6tg Месяц назад

    He's wrong

  • @Sunlightsam24
    @Sunlightsam24 Месяц назад +1

    Don’t take jabs!

  • @rudy6814
    @rudy6814 Месяц назад

    Wtf is he talking about

  • @anewsongpsalm333
    @anewsongpsalm333 Месяц назад +3

    Revelation 6:2 “And I saw, and behold a white horse: and he that sat on him had a bow; and a crown was given unto him: and he went forth conquering, and to conquer.”
    The word for bow is simplest of fabrics kind of like a mask.
    C (3-Abaddon)
    Ovid- latin sheep
    19- slaughter strongs
    Zechariah 11:4 “Thus saith the LORD my God; Feed the flock of the slaughter;”
    Revelation 18:23 “And the light of a candle shall shine no more at all in thee; and the voice of the bridegroom and of the bride shall be heard no more at all in thee: for thy merchants were the great men of the earth; for by thy sorceries were all nations deceived.”
    Sorceries- 5331 pharmakeía (from pharmakeuō, "administer drugs") - properly, drug-related sorcery, like the practice of magical-arts,
    1 Timothy 4:8 “For bodily exercise profiteth little: but godliness is profitable unto all things, having promise of the life that now is, and of that which is to come.”
    Blessings family...

    • @ShastaTodd
      @ShastaTodd Месяц назад +3

      religious spam... sigh

    • @LVArturs
      @LVArturs Месяц назад +4

      The title seems to have attracted the weird people.

    • @jik4107
      @jik4107 Месяц назад +3

      Brudda medicine is not sorcery. Why not to live better quality. I believe God but comon now 😂

    • @anewsongpsalm333
      @anewsongpsalm333 Месяц назад

      Keep in mind that the first male recipient of the covid vaccination in England was William Shakespeare. Covid was announced at pandemic by The WHO 222 months after 9/11. The first case of covid in the United States was 222 days after Donald Trump's birthday. When Barack Obama got covid it was 222 days after his birthday. If the world indeed is a stage you would have to ask yourself if this was coincidence?

  • @nadinejoyce1203
    @nadinejoyce1203 Месяц назад +1

    Why are you dressing like a 12 year old?🧢👕

    • @Tritiuminducedfusion
      @Tritiuminducedfusion Месяц назад +1

      You sound brain-damaged... or 90 years old. He only possesses 100X your intellect. Is this a fashion channel?🤡

  • @Cultural_Savant
    @Cultural_Savant 29 дней назад

    Or you can do everything right and get an extremely rare form of lung disease called Interstitial Lung Disease that's idiopathic and progressing, so now you're 35 on oxygen and can barley walk a block without being completely out of breath (with oxygen).

    • @rezedent9104
      @rezedent9104 19 дней назад

      I'm sorry to hear about that diagnosis. Life isn't fair, or just. I hope you (or whoever got the diagnosis) are able to get support. We are all here trying to learn a bit more, but life can be so cruel despite how much more "educated" we get.