Taurine: Aging Backwards? [Study 193 Analysis]

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  • Опубликовано: 28 янв 2025

Комментарии •

  • @Physionic
    @Physionic  Год назад +114

    *My recommendation for Taurine* * : amzn.to/3JZx08n
    AMENDMENT:
    I believe I mention that taurine is an amino acid (true) that can be used in functional proteins - this last part is incorrect; taurine is an amino acid, but it not involved incorporated in proteins through protein synthesis.
    Also, on a quick search (I haven’t looked into this deeply), taurine seems to reduce or attenuate increases in cholesterol lipoproteins according to a meta-analysis (DOI: 10.1016/j.ejphar.2020.173533). So, as I suspected, it isn’t much of a worry (I’ll need to confirm this) - some people in the comments of my last video on this topic suggested that taurine levels may be elevated in people who consume more meat (saturated fat), which could have an indirect effect on lipoprotein levels. This is a good possibility.
    *This has been independently lab tested for purity and contaminants; additionally, this is an affiliate link, but I have no relationship with the brand.

    • @SamsonFernendez
      @SamsonFernendez Год назад +11

      At your convenience of course :) Would you mind talking about nutrient synergies and how to do it in a whole foods manner instead of through supplementation? Not that I'm against supplementation, but just that eating common foods seems easier than picking out high quality supplements and keeping track of dosage and price changes between brands and variations.. Also it's a bit easier when eating animals because most nutrients are passed down from the animal's diet into ours, so would be great if you could help with non-animal based combinations for good/ideal nutrient synergies :) Thanks loads in advance :)

    • @Danny-mg1hu
      @Danny-mg1hu Год назад +2

      ah yeah! this is what i was looking for!!!

    • @artlion_4748
      @artlion_4748 Год назад +10

      Quick question for you if
      you don't mind
      In your opinion can Taurine help with reducing inflammation that is caused by psoriatic arthritis and hyperthyroidism?

    • @danwylie-sears1134
      @danwylie-sears1134 Год назад +3

      Thank you for including the correction that taurine is not one of the amino acids used in protein synthesis. I scrolled down to comments as soon as I heard the error.
      "Sapiens" as our specific epithet is a Latin adjective in nominative singular form, not an English noun in plural form. There is no such thing as "a Homo sapien".

    • @susymay7831
      @susymay7831 Год назад +6

      Are you taking taurine yourself?

  • @edd.
    @edd. Год назад +210

    Thank you for NOT shortening your videos. I understand we are all pressed for time in this world with work, family's, and social media. Knowledge should not be sacrificed to accommodate a schedule. I feel we should make the time to properly absorb and digest the material. You teach a lot of topics and the depth you cover is important. More importantly is your clear explanation of the material. Please don't change a thing and continue doing what you do!!🙏

    • @jonny9finger
      @jonny9finger 11 месяцев назад +3

      Absolutely I've learnt so much from this man with great data supports the theory. Last 5 months my energy level went thru the roof with his advice.

    • @Нфт-ц8и
      @Нфт-ц8и 2 месяца назад +1

      True

  • @fidelogos7098
    @fidelogos7098 10 месяцев назад +13

    When I was in college, molecular biology was a NEW major! That was a lifetime ago, and though I eventually wound up in computer science as a career, I still love to hear "trash" talk from biology people. I'm also interested in it because I'm getting old and looking for the Fountain of Youth. I've been taking Taurine for about 3 months now, but haven't yet noticed any significant changes. I'm thinking about increasing my dosage. Thanks for this and good luck with your studies.

    • @glenntimberlake2413
      @glenntimberlake2413 7 месяцев назад +1

      How much do you take?
      With food? Or before food?

  • @FreeKekistann
    @FreeKekistann Год назад +248

    My great, great, great, great grandkids will ask me if I’m on taurine 😊

    • @Physionic
      @Physionic  Год назад +67

      Hahaha! And you'll jump out of bed with your newly acquired bionic legs and say, "Kids, let's go dunk a basketball."

    • @jmc8076
      @jmc8076 Год назад +12

      Great attitude. Hope it happens. ✌️

    • @FreeKekistann
      @FreeKekistann Год назад +1

      @@jmc8076 🙂

    • @Tobias_Kevorkazito
      @Tobias_Kevorkazito Год назад +2

      🙏🌸😂

    • @rogerbritus9378
      @rogerbritus9378 Год назад +4

      By then that will be old news.

  • @discokillers8674
    @discokillers8674 Год назад +82

    First time on your channel. You explained everything methodically and clearly for the average person to understand. Great job!

    • @Physionic
      @Physionic  Год назад +3

      That's kind of you to say - thank you.

  • @JohanLofgren-jc4mh
    @JohanLofgren-jc4mh Год назад +55

    Thank you for not adding stupid background "music". Please let your channel clean. It is the important message I want to hear. ❤ your education.

  • @Michael-oj5pr
    @Michael-oj5pr Год назад +78

    Awesome you are doing this, finally good scientific videos. I have a physics background and really appreciate the time and effort you put in this. We need more people like you!!

  • @birage9885
    @birage9885 Год назад +157

    My, my, my, how time flies. I remember Pearson and Shaw talking about taurine back in the 80s, saying that someday this would be the new vitamin C. I have been using taurine that long, and what was an inexpensive nutrient will turn into the new darling, become scarce, and go up in price. The dark side to these studies. The GlyNac study did the same thing.

    • @jackbuaer3828
      @jackbuaer3828 Год назад +29

      If Durk Pearson looked like he was in 20s ,30s, 40s or 50s, I might say that he is on to something that turns back the clock. Based upon visual appearance (and that counts for a lot in my book), his regimen, if effective at all, would be modest at best.
      People are quick to discount visual appearance as a marker of aging, but it typically and readily easily allows us to distinguish between young and old (if no cosmetic procedures). There is no doubt about this. A 50 year old looks way different than a 20 year old. If one could truly slow aging, they're likely going to slow the visual markers as well blood and other biomarkers.

    • @midnightsnack1306
      @midnightsnack1306 Год назад +24

      @@jackbuaer3828I’m sure a lot of aging folks would certainly want to look like they are in their twenties forever but for people me I just want to be strong and healthy enough that I can still play tag with my grandchildren when the day comes.

    • @birage9885
      @birage9885 Год назад +3

      @@jackbuaer3828 Ha, ha, I can't argue that about their appearance. However, I think P&S did other things that sabotaged their ability to age slowly. Of course, at the time, science was limited on nutrient intervention, etc. Finally, if you use that as a determining factor to validate the study on taurine, it looks like taurine isn't as good as they are saying, lol.

    • @jackbuaer3828
      @jackbuaer3828 Год назад +9

      @@birage9885 I want to clarify that I was in no way meaning to denigrate their appearance. I was only trying to say that they look their age. There is nothing wrong with that. Most people look their age or worse. I was also trying to make the point that it is likel difficult to biohack aging through extreme efforts.
      So far I am not aware of a miraculous regimen or supplement that reduces the visual impact of aging. We see some Asian people that look much younger than their age, but many of them are not following a single regimen.
      If at some point we get a miracle pill or miracle regimen, I expect it will cause "across the board" improvements visual appearances among those over 50 presuming that have started the pill or regimen in their late 20s, 30s or 40s. Some people that look much younger than their age in their mid 50s or early 60s claim to do nothing out of the ordinary.

    • @damien2198
      @damien2198 Год назад +3

      @@jackbuaer3828 " I was only trying to say that they look their age" They were looking awful for their age

  • @justkidding9751
    @justkidding9751 Год назад +44

    Excellent vlog. I've been taking Taurine for six months and at 64 I'm feeling the benefits. But the best thing I found it useful for is my 8 year old Dog whose epilepsy has returned after 2 years on a medication called Epiphen. The seizures started back in August and as I keep a seizure journal I could see how these seizures have come back gradually until December from the 1st up until the 14th she suffered 16 seizures. After hearing it helps with brain dysfunction and is ok for dogs I gave my dog a dose and since the 15th December she hasn't had 1 single seizure. I have documented this and done a RUclips vlog confirming how it has helped her and I'm doing weekly updates. Unlike the Epiphen the Taurine may even extend her life and it's beneficial for her overall health which is more than I can say for the Epiphen. Anyone wishing to hear the progress on my findings can see it for themselves on my RUclips channel (Just Kidding) yes that's the name of it.

  • @Web3Dre
    @Web3Dre Год назад +62

    Thanks to Physionic I'll be an amateur molecular medicine scientist soon. Mom will be so proud of me 😃

    • @theantiqueactionfigure
      @theantiqueactionfigure Год назад +1

      Have you started your RUclips channel yet? ❤ 😂

    • @Web3Dre
      @Web3Dre Год назад +1

      @@theantiqueactionfigure lol. No I'm not as charming as Physionic. Maybe in another life😅

    • @Amandaetutor
      @Amandaetutor Год назад +1

      A new skill

    • @Amandaetutor
      @Amandaetutor Год назад

      That’s how I started 30 years ago - I now include all this in my regular teaching - they love it
      And it keeps me interested

  • @pocketsuperman7108
    @pocketsuperman7108 Год назад +15

    I am 51 and take Taurin 2 grams daily for 6 months. My sleep got better, my mood is like more balanced and i have more energy keeping low heard pace.
    I don‘ t know the reason, but my doktor seing my blood work, regading my LDL cholesterol asked me if i take any medicine. After my negative answer he said, that he has never seen so low cholesterol lebels on individual with my age without taking any pills.
    Regards

    • @Mikolas649
      @Mikolas649 7 месяцев назад +2

      Low TC And low LDL, contraindicated for longevity, despite what centralized doctors tell you

    • @hfctab3799
      @hfctab3799 7 месяцев назад +2

      Not so, can be the sign of efficient hormone activity. As high cholesterol is one of the signs of low thyroid function

  • @jmc8076
    @jmc8076 Год назад +83

    Only few min in and gave thumbs up just on quality of research and effort to organize data and facts for viewers. Brilliant. Thx Nic.

  • @pungar12aa
    @pungar12aa Год назад +90

    I have taken 7 grams of taurine for over 7 years to renew my lungs from smoking. I can now run without any issues, wheezing is gone, no more trouble feeling like I'm not getting enough air. I still smoke when I'm having cocktails. No apparent side effects.i suppose I should add that it has been 7 grams (7000mg) a day

    • @tullyapx500
      @tullyapx500 Год назад +21

      I quit smoking after 42 yrs of smoking. I didnt take anything, but I run regularly and only had wheezing and out of breath issues when I started running. I have no obvious ill effects from smoking. All we can offer is our own anecdotal evidence, and both ours have the same outcome with or without taurine.

    • @supernice_auto
      @supernice_auto Год назад

      you should just quit smoking- it's disgusting

    • @rogerbritus9378
      @rogerbritus9378 Год назад +2

      ​@@tullyapx500You don't say how long ago you quit. Give it some time and a different result could appear. Make sure you test your lungs frequently for abnormal growths!

    • @pjaworek6793
      @pjaworek6793 Год назад +5

      Interesting comments guys. Nick should do a video on respiratory issues. So much going on from alcohol effects on lungs, evali, covid, supplements like NAC, nmn, vitamins/minerals, omega3, ginseng, and now taurine.

    • @Utoko
      @Utoko Год назад

      Good for you! but anecdotes can be misleading and throw you of the fast of truth seeking fast. You could share where you based your assumption that it would renew your lungs on.

  • @markbrogan157
    @markbrogan157 10 месяцев назад +38

    I’ve been taking taurine the last month
    I’m 60 and I feel as fit now as I did when I was younger
    It’s amazing 🥊

    • @tiz6549
      @tiz6549 6 месяцев назад +4

      How much are you taking?

  • @TinselDoll
    @TinselDoll 11 месяцев назад +3

    I'm just so into these lectures of yours, Verhoeven.
    As a neurologist, all this is so fascinating to me. Immeasurably more fun than allopathic medicine.

  • @joel6427
    @joel6427 3 месяца назад +6

    I have been supplementing Taurine with 12 grams per day. My triglycerides were measured at 33, and LDL was equally low. There was no sign of disease in any other levels, including A1c, and no signs of dyslipidemia. At 76, I feel way too good to stop supplementing taurine for any possible negative side effects.

    • @akhileshp6419
      @akhileshp6419 3 месяца назад

      Any effects on creatinine or kidney function?

    • @AliceR27
      @AliceR27 Месяц назад +1

      12g is a huge dose. Wondering how things are a year later?

  • @cthornton523
    @cthornton523 Год назад +11

    Please do not shorten the vids. I want ALL the data. Thx Nic.

  • @zonkedoutzygote
    @zonkedoutzygote Год назад +19

    By far the best channel I've found for indepth explanation of studies. Thank you so much for taking the time.

  • @vicvin64
    @vicvin64 Год назад +13

    The algorithm is lagging i love this type of content and have never heard of you until now.
    I started dabbling with taurine 20 years ago when i was an idiot that took clen to get summer lean and heard Taurine prevents clen muscle cramps. The cramps were for real. Taurine seemed to help. I forgot about Taurine until a few years ago when i heard it helped with bile so i took it when i noticed digestive issues.
    Cut to a year later i read that taurine helps with anxiety by converting glutamate to GABA and potentially by reducing blood pressure which is part of the anxiety cycle ; feeling physiologically excited (heart rate hot face) thinking others notice this which is furthering nervousness. Anyways i had always been someone who lived with anxiety like literally sweating if someone i didnt know well was close to me talking to me for long enough to elicit this response. But i noticed as i read about this plausible taurine mechanism that i had not gotten that anxiousness since regularly taking taurine. So theres that.
    It also helped my sleep onset which used to take hours sometimes likely from anxiety over thinking when trying to sleep and taurine seems to just calm the mind it's amazing for so many things.

  • @rodrigsantsil
    @rodrigsantsil 3 месяца назад +2

    Your video is so FANTASTIC I'm going to turn on my TV for the first time in 11 YEARS ❗❗❗ so I can view all the graphs and charts of it and sturdy it properly.
    CONGRATS! 🎉🎉🎉
    Keep up the good work.

  • @LA_Viking
    @LA_Viking Год назад +8

    I'm watching this particular video for the third time to glean the maximum amount of information contained herein. I am a classically trained epidemiologist and tend to dismiss...or outright laugh at...most medical channels here on RubeTube. You have a winner and a subscriber.

  • @rodrigosanchez7539
    @rodrigosanchez7539 3 месяца назад +4

    Hi Nico, I love you content, I learn a lot and I am precticing my english listenig skill too , all good. Your channel is great... good vibes from Chile..

  • @TheEbulla
    @TheEbulla Год назад +10

    Don't shorten your videos. Wonderful lecture.

  • @ericbyrd5393
    @ericbyrd5393 Год назад +57

    Dr. Verhoeven, thank you for your work here. I've been supplementing taurine for about 10 years now, buying it in bulk packages of 1 kg and mixing it in drinking water in gallon jugs, with large quantities of MSM. My daily dosage is about 2.5 g of taurine. I started doing this only for this one reason: I had read that in places like Japan, where people are famous for their longevity, one of the isolated factors for this was that their diet was high in taurine. I didn't really learn much of the details until I saw your work.
    But there is one thing that troubles me. I also powerlift regularly, so building and retaining muscle mass is a priority for me. And apparently, taurine supplementation short-circuits the end of the mTOR pathway. I know there are several paths to activate mTOR, but apparently taurine suppresses the very end stage, of this special protein that is responsible for stimulating muscle protein synthesis, so it appears that regardless which way you approach mTOR, taurine suppresses muscle protein synthesis.
    There are several known compounds that do this, that are all associated with longevity and anti-aging: rapamycin (whence comes the name "mechanistic target of rapamycin" or "mTOR"), resveratrol, epi-gallo catechin gallate, etc. All are known for improving longevity, but suppressing mTOR. Apparently taurine supplementation has the same exact effect: it improves your longevity generally, by delaying cell senescence and the subsequent buildup of "zombie" cells, but it also suppresses the buildup of muscle mass. If this is right, it's very disappointing: if I want to retain muscle mass, I have to live with the normal aging pathways. If I want to delay aging, I have to live with my powerlifting not yielding one of the most desirable rewards of that work.
    Do you know of any way to get around this?

    • @rubensonorio8805
      @rubensonorio8805 Год назад +4

      Thanks for sharing 😅

    • @jac6541
      @jac6541 Год назад +14

      I’m very interested in the answers to this.

    • @justdave1
      @justdave1 Год назад +5

      If someone has a workaround, I'd like to see it myself. Until then the best path may be one of lowered expectations. It seems like living longer has more benefit. I suspect you have a lot of muscle allready, more than enough to take you comfortably into older age. I'm 72 and weak as a kitten, which I am fighting (with myself) to change. I've lost 80 pounds and time to work on some muscles. I need some but not really that much. I think Taurine will help me in general and not interfer with normal body building or shaping. If your one of the powerbuilding elite then your needs are specialized, I'd ask a professional somebody for advice.

    • @Lulu-kt6gr
      @Lulu-kt6gr Год назад +5

      Is it a significant amount of suppression? Meaning, would it keep a person from gaining bulk or would it keep the muscle from growing at all? As a woman I’m only interested in maintaining firm muscles that are also strong

    • @miriaml.150
      @miriaml.150 Год назад +14

      In regard to the dose you are supplementing with for taurine you may need to pull back. There's something called a hormetic effect. That means that something is more effective taken in a smaller amount and can actually harmful taken in a larger amount. I would investigate that as a pertains to taurine.
      (Dietitian since 1982)

  • @zoey907
    @zoey907 10 месяцев назад +2

    Please never stop making videos!! I just found you today & took my 1st Taurine!! (60)....Love how you take your time and break it down !!the longer the video the better!!!♥️

  • @justkidding9751
    @justkidding9751 Год назад +4

    This was a great breakdown of this study and you covered it well, and you put it into layman terms that we can all understand. You provide good evidence and as a 64 year old with a deteriorating spinal condition I found it encouraging and have now included Taurine into my diet. I have in the past 5 years made many changes in how I look after myself and the first thing I did was to stop smoking, then I worked on my weight and completely changed my diet and have been a pestcaterian for 2 years, I have gone from 18.4 stone down to 13 stone and I have a daily exercise routine. I include kefir in my diet as I understand the importance of gut health. I have managed to come off all my medications which there were many including Statins and blood pressure medication, and this vlog has convinced me that this is really an essential supplement that all over 50s should consider. Thank you for this breakdown on Taurine I found it encouraging. Great channel you're a good man. Thank you, Thank you.

  • @nvrancher
    @nvrancher 10 месяцев назад +4

    Started taking taurine and creatine because of you in depth reporting. Looking at glynac. I see you are somewhat ambivalent about glynac. Back ground, 74 yr old, went from sissy squats to 280/300 pound 3 set/20 rep squats. Thanks for all your help in understanding supplements.

  • @lsh6832
    @lsh6832 Год назад +2

    No need to shorten!!! Perfect concept!! Not average

  • @SeekTruth64064
    @SeekTruth64064 Год назад +15

    Fascinating research! If I understand this correctly, Taurine has so many benefits except for muscle development where it can be a negative side affect if trying to build muscle. If that is correct, then no elders should take this. I'm 71, petite, female and have been supplementing a 1000 MG. I feel like I have lost muscle not gained, even though I lift heavy weights. A clarification would be appreciated. Thank you, Nick, I love your videos and learn so much from you. PS: and you sure are easy on the eyes. 😊

    • @lovemissle
      @lovemissle Год назад

      Oh noooo😢. I just ordered a bottle from Amazon. 1000mg is that what I should take?

    • @lighthealerastrid1465
      @lighthealerastrid1465 Год назад +1

      @@lovemissle Oops so did I… the powder. Also 71 like Kathy and enjoying muscle hypertrophy.

    • @kiranbala90
      @kiranbala90 Год назад +1

      Powder is cheaper to buy than capsules.

    • @paulharrisonadventuregearm5457
      @paulharrisonadventuregearm5457 9 месяцев назад +3

      Taurine is fine for muscle development.

    • @paulharrisonadventuregearm5457
      @paulharrisonadventuregearm5457 9 месяцев назад

      ​@@lighthealerastrid1465dhea is your answer among a range of vitamins. In females a tiny amount of dhea is highly anabolic in older females

  • @jaredt1983
    @jaredt1983 8 месяцев назад +6

    Ok, hear me out. I'm 41yo, a reasonably healthy male. I've just started supplementing taurine and noticed some magical things started happening! Energy levels are up, very noticeably - I used to love working out but over the last few years I've somewhat deflated, lost my edge and will to work out - straight after supplementing taurine I started to feel the urge, the tingle to hit the gym and my muscles hard again! The quality of sleep dramatically improved, especially the falling asleep aspect, which in turn seems to have started to normalise my circadian rhythm. Borderline insomnia has been my struggle as long as I can remember. I've always dreamt of becoming an early bird - maybe now I have a chance to achieve it. But wait, there's more! Most importantly of all I noticed a dramatic improvement in my RSI (forearms) and radial nerve damage in my right arm. The pain has gone from severe to barely noticeable just after a couple of days of supplementing taurine. Before, I've tried everything, all supplements (apart from the taurine) and exercises, including the "nerve flossing" exercises, with very little impact. Looking forward to seeing what comes next. Best regards to all!

    • @JENNANDJUDD
      @JENNANDJUDD 8 месяцев назад

      I’m very much like you and libido’s gone lol since my youth and I hope this tablespoon a day helps my issues

    • @heidih3048
      @heidih3048 3 месяца назад

      What are your thoughts now, after a year regarding taurine benefits?
      Edit-- 4 months, not a year-- sorry

  • @osis1k
    @osis1k Год назад +2

    From a fan of orthomolecular medicine I love this delivery info.

  • @mboiko
    @mboiko Год назад +10

    Yes, it's VERY important to follow LDL/HDL results using Taurine in further videos.

  •  7 месяцев назад +2

    I’m so glad you didn’t shorten the video. Every second was time well spent. When I saw the length of it I thought I should just watch the intro and then listen to the rest during my daily walk. Once I started watching, I couldn’t stop. The visual information you provided was essential in helping me understand everything you said. Thank you for the time you spent creating this video.

  • @spockboy
    @spockboy Год назад +18

    Excellent work! Appreciate the time stamps for future reference.

  • @Wide_awake316
    @Wide_awake316 Год назад +2

    Thank you for not shortening these videos ❤️

  • @MannyWC
    @MannyWC Год назад +14

    Taurine is used greatly by the brain> GABA, the heart and the thyroid. I have been rx taurine for dysfunctional thyroid and elevated LDLs, anxiety…ETC for years. Scientific publications have documented all the above-- years ago. When it makes it to MSM/textbooks etc, it is 5-10 yrs old info if not older.

    • @lostinthoughts5645
      @lostinthoughts5645 Год назад

      So did you manage to significantly reduce anxiety and is your thyroid ok now? May I ask what is your dosage? Thx!

    • @MannyWC
      @MannyWC Год назад

      @@lostinthoughts5645 I am a doctor that prescribes it for these issues. Yes it works along with much other support. Dose is dependent…

  • @susanfisher4551
    @susanfisher4551 Месяц назад

    Thanks!

  • @RobertaPeck
    @RobertaPeck Год назад +11

    I love love love you as my RUclips professor!!!

  • @eddietrujillo7914
    @eddietrujillo7914 Год назад +10

    Historical I’ve been skeptical of taurine supplementation, but this new research has my interest. Excellent review of this research 👏🏾

    • @EdT.-xt6yv
      @EdT.-xt6yv Год назад

      Don't forget exercise & eating greens ,,,

  • @Nyonide
    @Nyonide 8 месяцев назад +2

    Great video!! And it is great that you stay away from advertisments

  • @citypsychotherapy3968
    @citypsychotherapy3968 Год назад +2

    A gastrointestinal transit test is a diagnostic procedure used to assess the movement of food and waste through the digestive system. It is often employed to diagnose conditions such as constipation or gastrointestinal motility disorders. The test involves tracking the passage of a substance (such as a radioactive marker or a capsule containing markers) through the digestive tract. The transit time is then measured to evaluate the function of the digestive system.
    To detect an improvement in a gastrointestinal transit test, you would typically look for a decrease in transit time. A faster Transit Time: If the transit time of the substance through the digestive tract decreases, it suggests that the motility of the gastrointestinal system has improved. This can be an indication of improved muscle contractions and coordination in the digestive organs.
    Good guess Nicolas!

  • @eldadyamin
    @eldadyamin 3 месяца назад +1

    By far one of the most interesting channels! Thank you!
    The research is amazing!
    The only thing I would add is your personal recommendation in regards to dosage, etc.

  • @Heirloom-HavenTeam
    @Heirloom-HavenTeam 9 месяцев назад +3

    Love this hardcore science. Excellent job explaining, and so patient with us! Thank you!

  • @glennthorn367
    @glennthorn367 8 месяцев назад

    Thanks

  • @KhalidKhan-sp9yq
    @KhalidKhan-sp9yq Год назад +1

    Mightily impressed Dr. Sahb. Im your newest subscriber

  • @brainwithani5693
    @brainwithani5693 Год назад +31

    I'd love to see a video on Thiamine- there are a lot of claims of it's health benefits in high doses and the different forms of it. Specifically TTFD and benfotamine.

    • @amylee9
      @amylee9 Год назад +3

      It helped my young son improve his stutter significantly. The effects would wear out but I would just supplement again while also trying other methods. He’s now a teen and no longer stutters.

    • @Bazza5000
      @Bazza5000 Год назад +2

      I hear a lot of people talking about that stuff, but don't know much about it. I am desperate to heal my gut health.

    • @brainwithani5693
      @brainwithani5693 Год назад

      @@Bazza5000 check out Elliot Overton

    • @brainwithani5693
      @brainwithani5693 Год назад

      @@amylee9 wow that's great!

    • @jenniferboehm514
      @jenniferboehm514 8 месяцев назад

      Benfotamine helped tremendously for my essential tremor for about a month. For some unknown reason, it stopped working. Frustrating. Finding that sweet spot of dosing has been difficult.

  • @HaMashiachSaves
    @HaMashiachSaves Год назад

    Thanks

    • @Physionic
      @Physionic  Год назад

      Thank you - just saw this.

  • @Gul0gulo
    @Gul0gulo 3 месяца назад +1

    This is an awesome presentation!

    • @Physionic
      @Physionic  3 месяца назад +1

      Thank you kindly!

  • @marccas10
    @marccas10 Год назад +406

    I knew an old guy, thin as a rake and he was always chugging Monster energy drinks. I have to admit to being worried for the guy. Little did I know that he was immortal.

    • @garyssimo
      @garyssimo Год назад +38

      33 grams sjger per 8 ounces will ruin his health.

    • @transkryption
      @transkryption Год назад +35

      @@garyssimo sjger is that the new street drug from Prague? or is that cake?

    • @user-fy7ri8gu8l
      @user-fy7ri8gu8l Год назад +25

      @@garyssimo Not really. Compared to what? What is his TDI for sugar? How active is he? 33g is basically jack shit for moderately active people that work out and do cardio during the week. It's a lot for S.A.D. metabolic disorder having American couch potatoes that are the problem. A person with a healthy metabolism really needs 60-90g per hour of zone two work out alone, a can of this will do nothing to them, American couch potato will need to shoot themselves with insulin just looking at it.

    • @kathybrown8533
      @kathybrown8533 Год назад +7

      recommended dosing for a 65 year old active female

    • @kathybrown8533
      @kathybrown8533 Год назад +7

      can this supplement help someone w/ cancer?

  • @tatsumakisempyukaku
    @tatsumakisempyukaku Год назад +2

    16:35. Over time we shrink. Hay, I was a tad taller than 6 feet in high school now that I’m 45 in a tad taller than 5’ 11”. I have back issues now. So, that degenerative joint disease is real. All you younger people take care of yourself. Your older version of yourself will thank you for it

  • @whitewolf6730
    @whitewolf6730 Год назад +2

    I supplement with Taurine, about 6G a day for longevity reasons. Are age of 68, I would like to be 67 next year thank you. I work out heavy 5 times a week, I also do creative and glycine.

  • @iamcookbook
    @iamcookbook Год назад +2

    awesome video, love the details you go into, keep your videos long!

  • @JimJim-md8ll
    @JimJim-md8ll Год назад +3

    Awesome presentation! You answered many of the questions I had as I've been taking Taurine for awhile now. Can you do a presentation on vitamins D3and K2 with respect to the circulatory system?

  • @tfokeefe
    @tfokeefe Год назад +12

    You have the most unusual talent to explain things very clearly, I am so glad I found you , I hope you expand your repertoire! 😍😍😍😍😍

  • @peggidoug
    @peggidoug Год назад

    Thanks!

  • @DebLeeMn
    @DebLeeMn Год назад +63

    Excellent info, thanks! Btw, bone mass matters way before 80 yo. Women start losing bone density in their 50's or even earlier.

    • @theantiqueactionfigure
      @theantiqueactionfigure Год назад +3

      They don't test men for bone density until it's too late. Don't ask me how I know!

    • @johna5484
      @johna5484 Год назад +9

      @@theantiqueactionfigureI’m a man and started getting tested in my 40’s. You have to ask. You are your own health advocate. Nobody else really cares about your health .

    • @Hack3r91
      @Hack3r91 Год назад +6

      Bone density peaks in your 20s, starts declining in your 30s and plummets from your 40s onwards

    • @bencyber8595
      @bencyber8595 Год назад

      yes, true

    • @TheMommom8
      @TheMommom8 Год назад

      Excellent presentation! A question..I normally always have a low white blood count , do you think taurine supplementation would be a problem? Thank you for all the time and work you invest in these podcasts!

  • @kevshan6518
    @kevshan6518 11 месяцев назад +2

    I would love to sit and chat with you. Amazing brain and fantastic break downs. I'm rebuilding after a sudden cardiac arrest. 42 mins dead. I have always had a huge interest in learning about naturally healing the body and mind. Love learning. If you're ever in Ireland, let me know 😁👍

    • @spoudaois
      @spoudaois 8 месяцев назад

      Look up Dr Dean Ornish who reversed coronary artery disease with nutrition

  • @lassereinhold9439
    @lassereinhold9439 Год назад +11

    I'm wondering what the taurine contents is in the lab food for the mice, fish and worms are. I know they use some form of standardized food pellets. But if these are deficient in taurine compared to the *natural* foods of the animals out in wild nature, then no wonder that supplementation has big effects. It's like: Give 100 mice food pellets with no vitamin C, and give other 100 mice food pellets + vit. C supplementation. Now watch how all mice in the first group die young, and conclude that "vitamin C supplementation doubles life span". But taurine is found in meat, so maybe baseline intake is already optimal in human?

    • @jb_1971
      @jb_1971 Год назад

      You raise a valid point, but note that there was an added benefit to a higher dose of taurine, which would be impossible to get from food alone.
      Also, I'm not a mouse expert, but I don't think mice have much taurine in their natural diet.

  • @danschweri
    @danschweri Год назад +1

    Incredible work you put in - thank you!!

  • @wmtnez
    @wmtnez 17 дней назад

    About why they reordered A, Y, and AT columns; well, it seems (according to the lines on the top) that they draw the two colums with closer values to the right. So in skeletal and brain cells the methylation values of aged taurin supplemented was closer to young, but it did not happen in liver cells.

  • @Laura-gx9jr
    @Laura-gx9jr 11 месяцев назад +1

    Just found your channel. Fantastic breakdown, Nick. 👍👍👍 Subscribed!

    • @Physionic
      @Physionic  11 месяцев назад

      Thanks, Laura :)

  • @larryfromchicago6526
    @larryfromchicago6526 Год назад +7

    Optimal dosing information should offered in the public segment.

    • @smarzig
      @smarzig 9 месяцев назад +1

      Left out purposely

    • @lizvaughn6598
      @lizvaughn6598 3 месяца назад

      The $19.95 hustle.

  • @wojciechkrupa9288
    @wojciechkrupa9288 Год назад +3

    really awesome video man, i really appreciate your work.

  • @carlogheller6779
    @carlogheller6779 6 месяцев назад

    I listen to your information while doing a work out at my gym! Not a problem!!😊

  • @gigisnippets6525
    @gigisnippets6525 Год назад +7

    I haven't watched the video yet, just read the title, but what I can tell you is, that I used to drink a lot of red bull (which contains Taurine) for most of my teens and 20s... im 27 now, and not drinking it as much anymore.. but as a 27 year old, I still get mistaken for a 16 year old sometimes, literally the other day I couldn't buy cigarettes for my mother because they were not sure if I was 18 or not. Maybe I should add that I'm vegan and also very careful about being in the sun and using spf.. so that probably adds to it too

    • @CampingforCool41
      @CampingforCool41 Год назад +2

      Yeahhhh I’m pretty sure it wasn’t the Red Bull that kept you looking young lol. A combination of good genetics and good skin care/sun protection will do the job.

    • @chuckleezodiac24
      @chuckleezodiac24 Год назад

      if you avoid the sun and eating animals, make sure you're getting enough Vitamin D.

  • @jackiemansfield8325
    @jackiemansfield8325 6 месяцев назад +2

    This individual has the discipline and the intelligence to be a scientist.

  • @joanhui2041
    @joanhui2041 Год назад +1

    Thank you for this informative video, very interesting.

  • @dlg5485
    @dlg5485 Год назад +2

    I don't currently supplement with taurine, although I am considering it. I found the section on WBC quite interesting because my recent lab results showed a low WBC which was initially concerning to me. However, I did some research and discovered that a slightly reduced WBC count is an indication that your immune system is likely optimized, i.e. your white blood cells aren't being called upon as much to fight infection and therefore are naturally lower. Lower WBC is indeed an indication of reduced inflammation. I should mention that I am very healthy... I do IF, exercise daily and take high quality immune boosting supplements, so a low WBC makes sense for me.

  • @salmanuel4053
    @salmanuel4053 Год назад

    He does the most entertaining research reports.

  • @kathleennorton2228
    @kathleennorton2228 Год назад +3

    L Taurine is the compliment of glutamine.
    If you are sensitive to MSG taking L Taurine can balance out MSG when you feel you have ingested too much of it. MSG is slathered into so many processed foods, even under different names.
    Truth in labeling is an org that is educational on how much MSG people are actually eating under different labeling.

  • @Jaco-b9f
    @Jaco-b9f 3 месяца назад

    I ❤ the bookmarking you've done on this video

  • @richglaser4566
    @richglaser4566 Год назад +2

    Thank you for this video. You a a brilliant man. Very interesting video

  • @That0therGirl
    @That0therGirl Год назад +1

    Great video. Extremely interesting.

  • @GIBZ1966
    @GIBZ1966 8 месяцев назад

    It is pleasure to listen to your lectures.

  • @MannyWC
    @MannyWC Год назад +6

    Nick so happy to hear you say “to be FRANK with you” instead of ‘to be honest’…!

  • @Peter-x29
    @Peter-x29 Год назад +2

    That's absolutely great channel! Thank you so much for your work

  • @redberries8039
    @redberries8039 Год назад +4

    Re. the elevated cholesterol etc: Dr Aseem Malhotra (cardiologist) and others don't seem to worried about them. I think he and others have speculated the statin reductions in mortality may be due to a decrease in inflammation? With all the positive effects of Taurine ...I dunno?

    • @redberries8039
      @redberries8039 Год назад +2

      @@MajesticArtimus It's complicated I don't have a sense of certainty about the issue, but that doc I mentioned is a respected guy. He's worth a listen.
      Genetic differences may account for you/hubbies cholesterol differences, different diets can benefit people with differerent genetics.

  • @kathyfann
    @kathyfann Год назад +2

    So glad I found your channel this is extremely interesting. Thank you!

  • @omvilla7469
    @omvilla7469 3 месяца назад +1

    Small comment on cardiovascular effects and Dislipidemia... As many probably know cholesterol and LDL are not really a concern any more and there seems to be no association with cardiovascular disease. On the other hand Triglycerides seem to be very much related since they reflect sugar intake. I see what taurine does and it seems that it should improve cardiovascular health as well...👍👍👍

    • @thetayz72
      @thetayz72 3 месяца назад

      Hi, I'm curious if you can tell me more about why cholesterol and LDL are no longer a concern?

  • @phillustrator
    @phillustrator Год назад +7

    Man, I'm binging on your stuff.
    If you get a chance to take a look at the omega 6/omega 3 ratio claims, I'd be very grateful.
    My intuition is that it's nonsense, but I would love to see a thorough break down by someone like you.
    Cheers!

    • @Nobody-Nowhere
      @Nobody-Nowhere Год назад +3

      It is nonsense, there are no real studies about it.
      Both, omega 6 & omega 3 are essential fatty acids, and both are anti inflammatory even in large quantities.
      If you are interested in quality content, check out channel named "nutritionmadesimple".

    • @limitisillusion7
      @limitisillusion7 Год назад +1

      I'm not convinced yet, but I have seen the video from NutritionMadeSimple. I would like to see more research. I have no problem with corn oil and inflammation in moderation. But if I eat a ton of it, it does cause me inflammatory issues. But I am more inclined to credit that inflammation to the caloric surplus that comes with eating a whole large pizza drenched in corn oil. Eating at caloric maintenance and exercise can work wonders for all this chronic inflammation, even if you're eating like crap.

    • @phillustrator
      @phillustrator Год назад +1

      @@limitisillusion7
      Buddy, the majority of the fat in pizza comes from cheese, the majority of which is saturated.
      Sounds like you really want to blame corn oil.

    • @limitisillusion7
      @limitisillusion7 Год назад +1

      @@phillustrator No, I used to eat pizza without cheese and the same effect occurred when I ate a whole pizza. I also get inflammation from eating too much fried potatoes or lean fried chicken. I don't want to blame corn oil. In fact, I love the stuff. I'm not convinced is all. I think inflammation is a phenomenon that we haven't quite narrowed down yet. My inflammation also decreased when my omega 6:3 ratio dropped to ~5.

  • @nurisadiandalu4382
    @nurisadiandalu4382 Год назад +6

    Would diet provide enough taurine as we age? If so, what food will give us enough taurine? Sadly, studies, nowadays, mostly always revolve around supplementation instead of real food.

    • @Nobody-Nowhere
      @Nobody-Nowhere Год назад +1

      No, you want to avoid foods that have taurine. As the best predictor of longevity is legume consumption ,meaning plant proteins.
      In the study, they used massive quantities that are nothing you can get even close from food. 250mg per kg of bodyweight, so around 20g daily!

    • @nurisadiandalu4382
      @nurisadiandalu4382 Год назад +1

      @@Nobody-Nowhere where in the study that says legume consumption is best? As far as i can tell, there is currently no study on taurine in human. Hence, that automatically negates any idea on food containing taurine.

  • @Cletus_the_Elder
    @Cletus_the_Elder Год назад +1

    This is the most thorough treatment I've seen here. I am considering supplementation, but wary of the sedative effects. Some report lethargy with taurine supplementation. I had a horrible experience with choline. Even taking a small amount of choline made moderately challenging tasks herculean.

    • @criticalbil1
      @criticalbil1 Год назад

      Choline didn't seem to do anything for me either, including soy lecithin and DMAE. Taurine is intriguing me though.

  • @petermichalantos5038
    @petermichalantos5038 Год назад +3

    You rock, Nick. Thank you. Your breakdown is perfect. As a newbee, I am looking forward to the rest of your content. No more researching for me. cheers champ.🏆

  • @kathyfann
    @kathyfann Год назад +2

    Thank you I love this wonderful video! We appreciate the Information!

  • @christinamilioni6325
    @christinamilioni6325 Год назад +5

    Great content as always!!

  • @mrich1625
    @mrich1625 Год назад +5

    I don't want you to shorten these videos whatsoever.

    • @Physionic
      @Physionic  Год назад +6

      I get a lot of comments saying I should, but I have zero intention of doing that, haha. Glad you're on board, mrich.

    • @mrich1625
      @mrich1625 Год назад

      🙌🏾🙌🏾🙌🏾

  • @carolematar3760
    @carolematar3760 7 месяцев назад

    Love your channel and your information dissemination

  • @andrewj2411
    @andrewj2411 Год назад +1

    Thanks for a great video. I really like the detailed, longer format.

  • @ski8799
    @ski8799 Год назад +6

    Great work, thanks. I’m on board but going in with extreme caution. We have been manipulated for decades and the research always points to supplementation vice some small dietary adjustment; i.e eat broccoli sprouts, etc. We all run out and spend hundreds of dollars, whilst telling ourselves “this is the one”. NMN, resveratrol, pterostilbene, quercetin, NR, spirulina, magnesium… and Taurine will have it’s day.

    • @florflor-i5h
      @florflor-i5h Год назад +1

      nr and magnesium good, topping up aminos is probably a good idea. those other things you list are good for the bin

    • @amperage8032
      @amperage8032 Год назад +1

      Agree, I’ve fallen prey to this. I’m much more discerning now. Diet and lifestyle continue to be my focus and I’ve paired down supplementation

    • @thisisreallife5086
      @thisisreallife5086 Год назад +2

      You're wrong on NMN. I have physical proof of its benefits (on myself). Not self-deception, but curing of a physical condition I had for 10 years until I made one and only one change - taking NMN.

    • @ski8799
      @ski8799 Год назад +2

      @@thisisreallife5086 I don't disagree with you, I was speaking general terms, I actually use NR myself, NMN is further up the pathway and would seem to be more effective than NR but far less studies on NMN led me to NR, still effective but safer IMO. Best to you and your journey.

    • @jorgeluisrodrigues1322
      @jorgeluisrodrigues1322 Год назад +2

      Collagen peptides.

  • @velikanskaglava2087
    @velikanskaglava2087 Год назад +2

    44:45 they switched it because it is a similarity tree, dendrogram, ordered by similarity, look on top of each stack image. Taurine works better on muscle and brain than liver (taurine aged liver is more similar to aged, than young).

  • @cdkslakkend5742
    @cdkslakkend5742 Год назад

    Wow, Excellent presentation. I thank you for taking the time to put this together. Incredible information.

  • @johnkennett3265
    @johnkennett3265 Год назад +31

    I am age 81, never smoked or used alcohol and exercise regularly but I am feeling weaker so I will seek source and dose of Taurine immediately.😅

  • @GaryHost-qs9pg
    @GaryHost-qs9pg Год назад +6

    Thank you for making this content physionic

    • @Physionic
      @Physionic  Год назад +2

      Thanks for watching, Gary. :)

  • @isa-manuelaalbrecht2951
    @isa-manuelaalbrecht2951 Год назад +2

    Nope no shortenings, much much too important what we can learn and whst you've to say..thanx and greetings from Switzerland - Isa 🤩

  • @HappyEddyMcGuire
    @HappyEddyMcGuire Год назад +3

    Great video! Can you go next level breakdown on oxalates? And then the link - bad link - between it and curcumin, which was a bummer to hear from a great oxalates doc video on YT. That's me asking. Who the hell am I to ask? I don't know, I'm just asking, you don't have to get pissy about it. A nod to your humor, which is awesome!

  • @stoppernz229
    @stoppernz229 Месяц назад

    I've been supplementing with Taurine for about 6 months...and exercising, body weight , high volume calisthenics type training, feel a couple of decades younger, much more mobile and strong, at 53 I'm even getting a 6 pack.
    I also take branch chain aminos and creatine everyday.
    also I'm a pretty solid drinker...which ya think would give me a beer belly.
    This video has given me a few heads up, cholesterol, I've always tested a bit high on the bad and low on the good, I consume less carbs more fat and not too much protein.
    Might get my cholesterol tested just to see if there's been any change.
    I've been taking 1/8th of a teaspoon of taurine in the morning, might up the dose if my cholesterol isn't too far out of whack.
    Cheers for the info.

  • @voltrading4966
    @voltrading4966 Год назад

    Thanks for another great video!
    Note that despite all the positives for hypotaurine the study doesn't discuss hypotaurine induced colorectal cancer which is well researched elsewhere.

  • @susymay7831
    @susymay7831 Год назад +1

    Good timestamps!❤❤❤❤❤

  • @ScottSummerill
    @ScottSummerill Год назад +6

    Taurine declines with age (what doesn't?). Did this study look at blood levels of taurine before supplementation? Meaning, was the supplementation simply bringing the blood level back to normal or was this a dose in excess of normal levels (mega dosing). I'm about to do an amino acid profile test. If my taurine comes back in the normal range do I still supplement?

    • @Physionic
      @Physionic  Год назад +3

      Back aches increase with age. :)
      If taurine is in normal range (for young men), then no, I wouldn’t supplement.

    • @rickbudslife
      @rickbudslife Год назад

      Deuterium

    • @nancysmith-baker1813
      @nancysmith-baker1813 Год назад

      I took a test done by cellular nutrition assays . A blood test , a natural path had me do it .
      My taurine was very low .
      But my B1 was ok . But I question this cause I don't swett perspire. That's a sign of low B1 .
      The test really help . I started to take taurine but not high doses now I will .
      I am going to go on ketoe diet geared more to carnivore.
      A regular blood test will probably not help .need a more indepth one .

  • @timdavis4332
    @timdavis4332 4 месяца назад

    The more information I hear on this nutrient, the more it sounds like its deficiency could be the cause of a bunch of symptoms that have been lingering,sometime before, and more so after having thyroid surgery, thats mess up my metabolism thoroughly.
    One thing that seems to be linked is a lingering problem with low body 1:05:56 temperature, which I guess taurine helps to regulate.
    But U've been all around the block, looking for a way to balance my metabolism, and so far ,taurine seems promising. 🤔👍🏻😌🙏⚡🔥