I am first year MBBS student and I have watched your many videos ...they always make the things very simple and easy to understand 👍🏻👍🏻 keep it up and thank u for amazing content
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9:22 ....I have question ..as u have said the alpha helix ends are slightly polar so they are neutralized by negatively charged group on N terminal end and positively charged group on C terminal end so I have to ask do alpha helices always end with *Lys* or *Arg* in C terminal end? I mean lysine or arginine is used to neutralize it to attain stability so would there always be Lys or Arg at that end?
not necessary ...we cant imagine alpha helix as a isolated entity ....in a protein there could be a long peptide chain and some part might take a conformation of alpha helix and some other part may take a conformation of beta pleated sheet....keep on watching this video series....things would be clear
brother it's my request to u that please make 11 and 12 ncert based biology animation vedio and form all chapter's playlist bcz these vedios help a lot to neet aspirants included me
Hi! is there a specific order for amino acids to be able to form an alpha helix? for exempel i had an exam question where they asked “ will this order of amino acid sequences form an alphab helix?” and the right answer were “no because every third amino acid is positive charged”
Different amino-acid sequences have different propensities for forming α-helical structure. Methionine, alanine, leucine, glutamate, and lysine uncharged ("MALEK" in the amino-acid 1-letter codes) all have especially high helix-forming propensities, whereas proline and glycine have poor helix-forming propensities. Proline either breaks or kinks a helix, both because it cannot donate an amide hydrogen bond (having no amide hydrogen), and also because its sidechain interferes sterically with the backbone of the preceding turn - inside a helix, this forces a bend of about 30° in the helix's axis. However, proline is often seen as the first residue of a helix, it is presumed due to its structural rigidity. At the other extreme, glycine also tends to disrupt helices because its high conformational flexibility makes it entropically expensive to adopt the relatively constrained α-helical structure.
No I am totally confident about the material .please refer to the following point. in alpha 3.6 (13 ) helix every mainchain C=O and N-H group is hydrogen-bonded to a peptide bond 4 residues away (ie O(i) to N(i+4)). This gives a very regular, stable arrangement. In contrast to 3.6(13 ) helix the 3(10) helix has a different pattern.Here the main chain hydrogen bonds are between residues separated by three residues along the chain (ie O(i) to N(i+3)). Literature support :www.pnas.org/content/pnas/100/20/11207.full.pdf check out the original feb 1960 nature paper as well www.sci-hub.ren/www.nature.com/articles/185422a0
Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8& You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
![Noob To Max With DRAGON REWORK In Blox Fruits [FULL MOVIE]](http://i.ytimg.com/vi/LnBMOinoOvA/mqdefault.jpg)
I am first year MBBS student and I have watched your many videos ...they always make the things very simple and easy to understand 👍🏻👍🏻 keep it up and thank u for amazing content
I will give you a detailed answer of your question soon when I am near my laptop. But anyway please share my videos with your mbbs friends
Have you passed mbbs test?If passed how many marks you got
Amazing!!! A lot better explained than my uni professors
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so cool thank you
Don’t forget to share with your classmates
@@animatedbiologywitharpan i sure will thank you ♥️
Awesome explanation and the animations looks so cool :) thanks bro
Please share my channel link with your friends and help me to reach big audience
around 8:02
- for Alanine you put the beta-alanine structure (you meant to put alpha-alanine)
- the structures of methionine and leucine are inversed
Have a quiz tomorrow, this helped me so much. Thank you kind sir!
It would be really useful if you could share my video with your friends. I am unable to reach many people, please share with your classmates.
Awesome explanation Sir, 😊
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Awesome... I've never watched such an informative and clearly understanding video I have exam tomorrow and this helps me alot thanks 😊
Please share my channel link with your friends and help me to reach big audience
9:22 ....I have question ..as u have said the alpha helix ends are slightly polar so they are neutralized by negatively charged group on N terminal end and positively charged group on C terminal end so I have to ask do alpha helices always end with *Lys* or *Arg* in C terminal end? I mean lysine or arginine is used to neutralize it to attain stability so would there always be Lys or Arg at that end?
Where is table 6.1 from? Like what textbook
It's from Lehninger's Biochem text book
Thank you!
Sir can we have videos on loops nd tertiary structure?
Soon those videos would be uploaded
Can you make a video on maxam Gilbert sequencing? Please
I need some time
@@animatedbiologywitharpan it's alright, you're the best study channel bro.
@@tunerd1921 please share with your friends
So, alpha helix structure contain one polypeptide chain??
not necessary ...we cant imagine alpha helix as a isolated entity ....in a protein there could be a long peptide chain and some part might take a conformation of alpha helix and some other part may take a conformation of beta pleated sheet....keep on watching this video series....things would be clear
@@animatedbiologywitharpan thank you. This is helpful :)
can you make vedio on structure of fibrinogen
sure
brother it's my request to u that please make 11 and 12 ncert based biology animation vedio and form all chapter's playlist bcz these vedios help a lot to neet aspirants included me
Please share my channel link with your friends and the videos would be uploaded very soon
Check out all my playlist.....you might find interesting things
Thank you sir. Clear and concise!
ruclips.net/channel/UC4IpyopsGWSjaPACNTZLuqg please subscribe to my other channel as well 🙏
Great sir 🔥🔥🔥
can we say peptide bond is hydrogen bond ?
No it's a amide bond ( covalent)
Then which is hydrogen bond in protein structure?
Hi!
is there a specific order for amino acids to be able to form an alpha helix? for exempel i had an exam question where they asked “ will this order of amino acid sequences form an alphab helix?” and the right answer were “no because every third amino acid is positive charged”
Different amino-acid sequences have different propensities for forming α-helical structure. Methionine, alanine, leucine, glutamate, and lysine uncharged ("MALEK" in the amino-acid 1-letter codes) all have especially high helix-forming propensities, whereas proline and glycine have poor helix-forming propensities. Proline either breaks or kinks a helix, both because it cannot donate an amide hydrogen bond (having no amide hydrogen), and also because its sidechain interferes sterically with the backbone of the preceding turn - inside a helix, this forces a bend of about 30° in the helix's axis. However, proline is often seen as the first residue of a helix, it is presumed due to its structural rigidity. At the other extreme, glycine also tends to disrupt helices because its high conformational flexibility makes it entropically expensive to adopt the relatively constrained α-helical structure.
Please share my channel link with your friends and help me to reach big audience support.
very very helpful, thank you
Please help me by sharing with your class mates
just a small concern on the material of this video. H-bonding between alpha C and N in the backbone isn't it between 1st C and 4th N (n+3 not n+4).
No I am totally confident about the material .please refer to the following point.
in alpha 3.6 (13 ) helix every mainchain C=O and N-H group is hydrogen-bonded to a peptide bond 4 residues away (ie O(i) to N(i+4)). This gives a very regular, stable arrangement.
In contrast to 3.6(13 ) helix the 3(10) helix has a different pattern.Here the main chain hydrogen bonds are between residues separated by three residues along the chain (ie O(i) to N(i+3)).
Literature support :www.pnas.org/content/pnas/100/20/11207.full.pdf
check out the original feb 1960 nature paper as well
www.sci-hub.ren/www.nature.com/articles/185422a0
Please make lecture video on Riboswitches
Ok it would be uploaded soon
@@animatedbiologywitharpan thank you sir🙂
IFAS biochemistry ka playlist me upka vidio dekha?
Thanks for informing......I don't know how that happened....I am not linked with them
@@animatedbiologywitharpan Ha ha, actually upka vidio slides bahot famous hai😂😂
Anyway please share my channel link with your friends and help me to reach big audience
Sir can u explain about major and minor groove of DNA
Yes very soon there would be videos on that
But please take some time to share my channel link with your friends and help me to reach big audience
@@animatedbiologywitharpan yes am already shared among my frnds sir
kamal💯
Please share my channel link with your friends and help me to reach big audience
Dada Tumi Kon book follow korecho ba korechile etar jonno?
Lehninger/ Voet
Nice👍👍
Please sharee with your friends and help me to reach big audience
I used this for last min uni prep
Worked out great
Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me
Why there is no translation 😕
I am really sorry for the inconvenience
@@animatedbiologywitharpan its ok , i hope you add translation at your next videos
Awesome
please share among your friends
@@animatedbiologywitharpan yeah.Nice work.I really like your animations
اللهم صل على رسول الله صل الله عليه وسلم
could not understand
HBB gene 🧬 147 honey 👌🦚🐝
Wow.... Thanks
Please share my channel link with your friends and help me to reach big audience
@@animatedbiologywitharpan sure Sir
لا اله الا الله وحده لا شريك له, محمد رسول الله
Thanks
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
As a gd player I would add one to the start of the name
Tq sir
Please share my channel link with friends and help me to reach big audience
HBB gene 🧬 147❤ honey 👌🦚🐝