Splicing and Dicing DNA: Genome Engineering and the CRISPR Revolution
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- Опубликовано: 18 май 2024
- CRISPR: It’s the powerful gene editing technology transforming biomedical research. Fast, cheap and easy to use, it allows scientists to rewrite the DNA in just about any organism-including humans-with tests on human embryos already underway. The technique’s potential to radically reshape everything from disease prevention to the future of human evolution has driven explosive progress and heated debate. Join the world’s CRISPR pioneers to learn about the enormous possibilities and ethical challenges as we stand on the threshold of a brave new world of manipulating life’s fundamental code.
This program is part of the Big Ideas Series, made possible with support from the John Templeton Foundation.
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Original Program Date: June 3 2016
MODERATOR: Richard Besser
PARTICIPANTS: George Church, Luke Dow, Josephine Johnston, Ben Matthews, Harry Ostrer, Noel Sauer
What is CRISPR? 00:00
Introduction by Richard Besser 3:58
Participant Introductions. 5:02
What is so powerful about CRISPR? 7:25
How is CRISPR is used? 13:00
How will CRISPR help eliminate Zika Virus? 20:45
Modifying 60 genes at once in a pig. 26:02
What are potential agricultural advantages from CRISPR? 28:44
If you have eaten CRISPR cells? 35:00
Using a gene drives to eliminate virus? 37:40
Creating an off switch for CRISPR 40:27
How is it ethical to not rid the world of malaria? 42:55
What is the difference between editing a germ line and editing a cancer cell? 48:27
Why would the first CRISPR baby create backlash? 58:48
How do we regular CRISPR used in military applications? 1:06:33
What is the regulation to be expected from CRISPR? 1:13:09
What does a CRISPR-ised world look like? 1:16:00 
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Why subtitles are not working please help
This experiment from the human aspect already failed...This is 2022 and we know international groups involved with the topic of our day always show humans involved are guilty of doing the unimaginable for personal gain...As far as science goes the history of experimenting on the public without their knowledge is well established...
@@marcgottlieb9579 Agreed, well said.
Your Chinese friend is the one who modified SARS virus replicated RNA to produce the various strains of COVID virus to use it as a pandemic driven reser of Global economics.
It makes me really uncomfortable that the World Economic Forum states that ‘RNA Technology’ is the
‘Gateway’ to Transhumanism. Where are the Doctors that should be protecting us from this?
CBDC's and Crypto need Electricity and the Net , They can Never be Honest Money on a Scale like Silver
and Gold
Satoshi Nakamoto Means your Death , Your wealth is at the Whim of Others Blockchain was Made to Keep
the Wealthy
holding Wealth and The Undereducated Broke
Do you want to be the reason your grandkids get Killed by Digital Programmable Money ?
Digital Programmable Money . CBDC's like China , Everything like China for your descendants .your fault
?
Digital Money is a threat to Mankind , The End Result is we die leaving the children with their Doom
and Demise
My last Vaccine was in the 1973 - 74 School Year , I will not allow an Ethylene Oxide Swab in my
Head , so COVID 19 is just a Lie to Me , I had a flu in Jan 2020 it went away , I feel great and I
will take it as a "threat to my life" if you come at me with a Swab or Jab.
What frightens me the most is that all are saying that they want to help humanity but then they only talk about "products". Notice any lies here?
ZSSolomon it's because of the chemistry background. A reaction has an educt and a product. So I guess they say it because of that and don't think about it in the commercial way
They are going to try and starve us all to death .
They're not referring to the commercial 'product'. They're using product as in ' 4 is a product of 2+2'. In this example, the number 4 is not something you can actually buy, 'product' in this context just means the result of a process.
Crispr Cas9 is a great achievement, and rightly so. But, as was to be expected, the military recognized this very quickly. They realized that Crispr can also be used to modify viruses. There is always money for that. Was this also how the coronavirus was developed? Viruses, fantastic weapons. Easy to transport, hardly any trace of where they come from. And they have an enormous threat potential.
BIO WEAPON CREATION.
@@angela8187 There is no reason to assume covid was made with crispr
Specially for people like you they recently combines original coronavirus with 80% mortality with omicron version which has 80% virulence.
Just to show you how really human made virus should looks like.
@@danirabinowitz5049 cause it probably was
@Dani Rabinowitz But you always have a lot of delusional trumpanian conspiracy believers around ¯\_(ツ)_/¯ 😂
This video was produced just a little over 4 years ago. I'll have to watch it again. Should be a million hits on this. Amazing information.
You only like it because that big fat elephant in the room (man playing god) gets totally ignored per usual big money interest only interested in profit, you shaved headed psycho-ignoramus.
AI made the Moderna shot. Think who is overseeing the engineering ...
The devil what do you think AI is
Genetic engineering if done correctly can be more important and revolutionary than splitting the atom. However genetic engineering at the moment is like a blind man leading another blind man around. Meaning unless we find out exactly what each sequence and strand of our DNA does and what effect it has in our body or the role It plays. We should not blindingly be modifying anything because the consequences could be disastrous.
Yes. Dude 5050 I think you're exactly right.
I really hope and pray that true information is shared and not just biased what they want you to know information.
But think of all of the people who would benefit from this if intended n applicated correctly in many healing forms and avenues.
The consequences could " Be " disastrous .
I'm sure Fauci agrees
I see this as the ultimate cure for genetic problems. Familial mental disorder, systemic disease, and the fall of IQ in the past three decades. Obviously the last is controversial.
Yet the panel only talked about the negative consequences for a full 37 seconds.
Yeah I trust these guys with my genetics 🧬 makeup !?🤪
There is multiple layering of information in the genome. It is read forwards, backwards, on both sides and now there is also another layering of information across the genome. Change one thing and you could be changing multiple functions.
Yes
nothing's impossible, we will master it someday, but you always have to crack some eggs to make omelette
Martin Kočíšek It is impossible because everything falls apart at a much greater rate than they supposedly fall into directed working order.
+Seekmosttoprophesy they would also have to test it on people I doubt most people would sign up for it do they' probably would either test it on prisoners or force people to do it which is a dick move either way
there are terminally ill people who will sign up and all kind of geeks and enthusiasts
This technology has so much potential, for both good and bad outcomes. Hopefully with the right amount of education, proliferation, and regulation it can make a reality of the dreams of each one of the panelists. I remain skeptically optimistic though.
Cool, like Blade Runner.
You feed the world by improving the soi and doing smal scale organic farms.... you prevent disease by ending the hiearchy of wealth and health, and by feeding the body well, with nutrients. vitamin c could save billions of dollars if given to everyone. reduce disease? out law mcdonalds and other companies selling death. High falooting folks with big salaries see to have no time to think about basics and the rise of disease as an outcome of cultural practices
Governments will say that they are regulating it but they will really be sponsoring it to suit their own ends. The genie is out of the bottle. Now, we will see where this all goes but trying to regulate it will be futile. Even the countries that cry for regulations won't abide by their own regulations. None of them will. They don't trust one another, as well they shouldn't. This is going to go into a lot of different directions and you can be sure that some of them will be bad. But regulations will be a joke.
This is America, there is no regulation because the regulators have been corrupted. The FDA is Mansanto...the list goes on. Proven facts.
Thank you for the informative video. Worthy to be viewed again while taking notes. Enjoyed seeing George Church and hearing what he had to say.
Dr. Doudna is one of my heroes.
Excellent moderation. Nicely done Dr. Besser.
This is all about GMO of everything - PERIOD!!!
Island of Dr Moreau . Unless those days were cut short no flesh would be saved ,Book of Matthew.
In the future internet companies won't just sell our contact information. They will sell our DNA information. That way they can predict what medicine we need, how tall we are, what hobbies we have, what we like and other stuff. This is like having your address and life history.
I love how they always say oh it's going to be a cure for cancer for 60 years I've been hearing that and I have yet to see them advance in any kind of way with all their technology
Right
C mon can't you wait 60 more,china will.
The only thing this cures is reasonable moral reponsibility.
It's atheists all the way down to the devil, Goddammit!
There is no profit in a cure. The money is in life long treatment. Nothing will ever be cured again. This is our world now
"I'M LEGEND"
as far as creating 'super soldiers' or 'super bugs', the only entity interested in such things would be a government.
Yes.. application is key.
I have to believe that the government is good and so is the true nature of mankind and very hopeful in the endeavors of curing. I just am a bit puzzled by how they are releasing the technology.
Like pushing these vaccines as a one size fits all.
I just saw a little girl with a terrible skin disorder. I believe that the technology exists to fix this. It's just getting it to her...
I wish I had a magic wand.
Or anyone looking to make a whole lot of money.
Editing an empryo of humans will cause significant problems down the road. We are an incredibly delicate balance of biological function. Changing an adult will be much safer believe it or not. But doing so to an embryo could cause unfathomable complications.
Playing with embryos like that is a crime because there’s a thing called CONSENT.
There is no way to stop the abuse of this technology!
To think we can make laws to prevent misuse is naive.
@@benhof2140
Getting to play god, for good or evil.
WOW. Can mankind be trusted with
such technology? We can only Hope
and pray for the best.
When my local Chinese tailor made alterations to my jeans, he said that he was a Jean Editor.
Dude :D I'm striked out with this one
Next step will be whole process gen editing of really long stretches if chromosomes even to create new quimeruc speciea from virus bacteria to pluricelular organisms and transplantable organs We are just beginning By the way its extremely easy to wipe out the human speciea with an edited lethal coronavirus..You havent many developmental editing ussues both in DNA and ARN
😂😂😂
Now Bill Gates can help edit the human Genome
How'd u get in those jeans' - genuine 🎵
Very interesting topics indeed and also What and Excellent findings of crisper Cas9 ! 🙏
For every action there is a reaction so is this really flawless
Yes. But the reaction is a cure for many, many diseases this time.
+OmniversoSinDios but what I'm saying is that it's the cure for the diseases we know of but the power to beat contains the structure to fall victim to something knew one it gets put into a world full of bacteria.... So yeah there goes cancer but what's next. The only fool proof way for this to work is by making the biggest threat something we have a cure for already like interlacing it to some like the common cold of the fule something we understand,
+gh0stly1777 sorry for my spelling errors I'll do better next time,
Best videos on the web. Thank you very muhc
Hi. I'm Heather McLaughlin. I think this video is so exciting and interesting. There's so much to offer the work through CRISPR
I love this channel ❤️
Nice video. Keep it up
Goose bumps
Nice jobs,thanks share
this is basicaly installing mods for games, but with human dna in the real world
some mods contain viruses and malware which can damage your system :)
Dello Morgan good point. but i think the benefits still outweigh the risks, and you should always make sure you get your mods
from a trusted source and look look at the effect they have on other peoples machines first
your right If we can genetically modify the DNA before the kid is born to prevent the kid from inheriting any genetic disease or birth defect this would we awesome.Its not as easy as it sounds I think in about another 50 years we will be able to prolong life and as long as this is used for the good reasons its cool. :).Hay I always download mods from credible sources and learn from others mistakes,but don't forget that person learnt the hard way!
That's exactly how I think of it, or like modding an Android device.
+Dello Morgan Try, in the next 15 years, the only things holding this technology back are people's feelings otherwise known as morals/ethics and government suiting the needs of idiots, of course there are obviously the genetic detriments but those are the only real problems that should be considered.
Man will achieve anything he puts his mind to... the problem will be when he doesn't want the consequences of his actions that he will absolutely be accountable for..
Using it now in human beings on a worldwide scale
Yep in the jab.
Funny, that was my exact first thought.
@@Verde212 Because you are a wise person. LOL God Bless you.
@@Verde212 It is in there. Look up the patent for the different pharmacueticals who are marketing the savior jabl
Don't mind my approach. Clarity, coherence, and adequacy concerning...is vital! What is to persevere? But to observe! How else? Can...
how come the cas9 protein can produce overhangs. I mean if I am interested in inserting a certain gene it's better to produce overhangs like the case of some restriction enzymes actions so parts of the DNA to be inserted can hybrid with the overhangs eventually being inserted. how cas9 can accomplish such thing?
Starts at 7:40
Wonderful discussion. Thank you.
Moustache guy at 1:09:43 is so wholesome. I wish he were my dad.
Kurzgesagt
Their video was better.
ikr
do you mean kursgesagt or this one was better
Everything is better if made by Kurzgesagt :)
For the ignorant ones here--- tell us who or what the fuck is this thing?? I kow I can look it up, but if you took the time to post it at lest say what the hell it is, you pedantic fool.
Around 1:08, he is talking about creating super soldiers as bio weapons that is not only the concern. He forgot to think on such techniques of "targeting the specific area" could be used as the bio weapons "like the kill button to switch off or overload of the person who can't handle the information or neurotransmitters of the person's brain's electronic synapses", perhaps in the case of getting attacked by the electriric nuclear super sonic attacks. As far as I observed the concerns on the worry about the application of such technical skills and the knowledge on the thema of bio weapons use. 🧐 Because the team has been forgetting to think about the good technical skills are not creating super soldiers, but the purpose of killing the enemy to kill or uour patients to to heal and let live healthy are on their hand by choice. That is the most serious concern of the applications under the abuse by the terrorists with advanced level of science, when the good such skills will be not used as therapeutics. CRISPER is wonderful technical improvement, yet under the abuse of bio terrorism "kill or live switch buttons". The noise from upper level of educated scientists have been silenced, it seems.
Mari Kleinen,
CRISPR is an attempt of genocide, it is eugenics creeping through the back door. We know they are going to eliminate those of us who don't want to be cured, just like they're already trying to destroy Down Syndrome.
What makes it their choice who is worthy of life?
Great video, sincerely appreciate it and praise GOD for smart intelligent people!!!
Thanks for sharing!
🌼🌼🌼🌼🌼🌼🌼🌼🌼
God, really ... ? Is that suppose to be funny ? I mean, GOD was a very smart and busy scientist wasn't he/she that wrote so many DNA sequences, created so much matter on Earth and universe.
+Pleb Schmuck
Really, never stop searching!!!
Keep looking🔎🔭📡🔦💡🏮📕📖📚📓📒📃📜📄📰
"SEEK AND YE SHALL FIND!!!"
~ BIBLE ~
Great discussion and good moderating. In the limited time the panel has most of the important aspects of the topic were discussed (of course we now have the first human babies gene edited so will wait and see). Thank you!
When government sees how good this works, the race will be on. If it isn't already. AI and Gene Editing. Both exciting and scary at the same time
@@jimbobaggans1564 more like the race will be over; they will dictate life and death of any family or peoples they want to.
STILL trying to acsertain WHY that thumbs down button is there.
with this technology is it possible to take an egg from the great apes (24) fuse the 2nd and 3rd chromasomes to make 23 egg add 23 male homosapien place egg in surrogate would the offspring be similar to a pre human?
as taj mahal said "if you ain't scared you ain't right"
6yrs later..now., I hope we have figured out , Environment, Habits, influence, drive many Decisions we make for our lives and others within our control. 😇 👼
this is both amazing, but also scary... this reminds me of bioshock so much
Let us continue to move forward into long life and better health...
It will destroy lives, not save lives.
Can you recall homosexuality defined as a pathological disorder? Hitler and racial hygiene? Females are intellectually inferior? Black people are not even humans? Why were alternative races defined as diseases? Humans clearly cannot be trusted, they will no doubt abuse people with it with selfish motives. You probably think that's pseudoscience, but no, they were the claims the best scientists of their day concluded, it was bad science based on confirmation bias by racists as CRISPR is bad science by ableists.
I am autistic and I don't want to be cured of the gifts that come with it, they should not have the right to change people without our consent, it is racism and discrimination.
Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution."
Evelyn Fox Keller explains:
"We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution."
The mutants behind autism offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction.
Psychologist Howard Gardner warns:
"With the coming of age of genetics, the danger magnifies. Beyond doubt we will discover genes that are important for reading alphabetical scripts; and there is already evidence that a small set of genes may be related to reading problems. As with the brain evidence, such information can be helpful for early intervention; but it could easily be used for stigmatising purposes. Indeed, it might become relevant for marriage prospects, holding a job, securing insurance, or even eugenic purposes. And no doubt, especially in our interventionist society, individuals with a genetic predisposition for reading problems will look into different kinds of genetic engineering or therapy. It is possible that such interventions will work and have no negative side effects, but it is perhaps more likely that they will have unanticipated effects. And we might even want to consider which valued human abilities - eg. spatial or pattern recognition skills - might be placed at risk were we to target our interventions specifically at reading disorders."
We can see the vast majority of so called diseases for what they are; they are discriminatory social constructions, not an intention to objectively understand human biology.
Were global warming, warmer oceans, production of epidemic diseases, climate change, increased natural hazards and more anticipated? I doubt it so I would say Howard Gardner has a good point, every time humans have tried to play God and control nature nature struck humans back with greater problems, the people trying to solve the problems are the people who caused the problems and are trying to solve those problems repeating the same mistake to cause more problems.
Since those of us you define as "genetically inferior" have abilities those you define as "genetically superior" don't have, doesn't that mean "normal" people are genetically inferior as well?
This is no different to the eugenics movement.
Recently a whole bunch of genetically modified mosquitoes were released in Florida where I live to solve some problem… so far so good I think!
Wait until you get bite by one it don't kill then call Dr.Fauci
According to Bard:
Yes, a whole bunch of genetically modified mosquitoes were released in Florida in 2021. The mosquitoes were released by a company called Oxitec, and they were designed to help control the spread of mosquito-borne diseases such as Zika, dengue, and yellow fever.
The mosquitoes were genetically modified to be male and to carry a gene that is lethal to female offspring. This means that when the male mosquitoes mate with wild females, the female offspring will die before they can mature and lay eggs. This helps to reduce the overall mosquito population, which can help to prevent the spread of disease.
The release of the genetically modified mosquitoes was controversial, with some people expressing concerns about the potential risks of releasing genetically modified organisms into the environment. However, the Florida Keys Mosquito Control District, which approved the release, argued that the risks were outweighed by the potential benefits.
The release of the genetically modified mosquitoes was a success, and it is estimated that they helped to reduce the mosquito population by up to 80%. The company is now planning to release more genetically modified mosquitoes in Florida, and they are also considering releasing them in other countries.
Here are some additional details about the release of the genetically modified mosquitoes in Florida:
* The mosquitoes were released in the Florida Keys, a chain of islands off the southern tip of Florida.
* The release was approved by the Florida Keys Mosquito Control District.
* The mosquitoes were released over a period of seven months, from April to November 2021.
* The total number of mosquitoes released was 144,000.
* The release of the mosquitoes was a success, and it is estimated that they helped to reduce the mosquito population by up to 80%.
The release of the genetically modified mosquitoes in Florida is a significant development in the field of mosquito control. It is the first time that genetically modified mosquitoes have been released on a large scale in the United States, and it could pave the way for the wider use of this technology to help control mosquito-borne diseases.
I need jean editing so I don’t have to undergo diet editing.
They need to make the flagging system less accessible or move it.. I keep bumping it when I change the vid quality.
This is not good ,our lives in the hands of corporations ,Island of Dr Moreau ,The Fly,Framkenstein,Borg assimilation.
Great panel and discussion!
We are rediscovering what our ancestors did in the past --' the Annunakis
you mean our masters don't you?
and creators
43:00 Question of ethics of life saving vs. eradication of vector of transmission(in this case a mosquito)
Id be better to viruses and protozans though, wouldn't it, get to the heart of the problem so to speak?
Eradicating a natural disease vector introduces the laws of unintended consequences... we are seeing that law in its full fury as the results of massive amounts of CO2 are being released into the atmosphere... what happens to fish and frog populations if we kill off all mosquitoes for example?
So interesting
There are tuns of low-hanging fruit. For example, re-enabling the gene for vitamin C production.
Best videos on the web. Thank you.
A blueprint for utter madnes, the end of humanity, how to exploit paid morons, etc. Yeah, great video you utter waste of a human shell!
Plants that can grow unlimited amounts of food with very little resources.
Yeah, I foresee corn stalks 20 ft. tall with 50 ears on them and cows the size of elephants.
i foresee 5 meter long sociopath "peacekeepers" ...LOL?
i see human pikachu coming soon :O
dude you thinking too small why do we have to eat
b/c you can't sustain a cell with pure nothingness, cells are constantly expelling energy which in turn require energy. the laws of physics clearly states, you cannot create nor destroy energy
These technologies give me a sort of nihilist feeling. Our genetic code is meaningful, it is a product of millions of years of selection and game theory, the synthesis of many strategies and algorithms battling it out in ever more cunning and refined ways. While this is all very promising, indeed, this is our holy grail, it also makes me feel that we are all just code, just programs that can be changed on a whim. Hopefully we manage to keep in perspective the geological timescales that brought us here and remain grounded, avoiding the mistakes we have made when we dared to engineer darwinism and economics in the beginning of the last century.
R u get chills
Noel Sauer, please take note. You are using 'actually' obsessively. I believe you could eliminate it completely without any deleterious effect on your messaging. It certainly would make listening to you more enjoyable. Can you use CRISPR to extract a word? 🙂
Democratizing technology Doudna is awesome!
00:12:07
Who on Earth is George Seed? I don't recall him being introduced.
{:-:-:}
Does anyone the title and artist of the music that is play at the when the credits are running
I believe Ancient humans knew about DNA splicing. From what I’ve read, it’s talked about in the Dead Sea Scrolls.
Big Ag and Big Pharma dive in head first! No surprises there. You will always see huge promotions like this for CRISPR when these two giant industries are involved. We are playing with things we have failed to understand in the first place.
Typical comment from ignorance. We've been breeding animals and plants for thousands of years. Go pull up a picture of what an ear of corn used to look like before farmers 100's of years ago altered it genetically, yeah Big Farma :). Sometimes it goes smooth, sometimes there have been manageable issues. CRISPR is just breeding without totally unpredictable results that occur in traditional methods. You target the specific gene sequence(s) you want to change without involving the part of the gene that you really don't want to change. You can get a corn plant that is drought tolerant without potentially effecting taste, for example. Furthermore, bacteria are used to do the editing - the same bacteria have been editing on their own for millions of years before scientists put them to use. Similarly spontaneous (natural) mutations occur in living organisms all the time, and we have no control over that either.
I agree with the commenter.
This can be used for good or bad.
It can go disastrously wrong.
Follow the money 💰
@Keep Calm please elaborate on your evidence of this "rushing". Did you not read my previous post? Humans have been breeding various forms of life for thousands of years with incremental technologies. And CRIPSR is just human control over a natural occurring process. These fears of yours are akin to when people years ago thought physicists would destroy the earth by building and running particle colliders, a controlled collision of the same atoms and subatomic particles that crash into each other regularly everywhere throughout the universe -without any help from humanity.
@Keep Calm You seem to be the one who is arrogant. Get familiar with this natural occurring process before you opine on it - these DNA edits have been occurring on their own, since the earliest life appeared, long before humans did any coaxing. Furthermore, you should understand that the biological definition for breeding is, To develop a kind of animal or plant for a particular purpose or quality.
@Keep Calm Sorry but I'm not talking about your ethics concerns - my response was targeted to the original poster's notion that "we are playing with things we have failed to understand " which is total BS, and your comment that we are "rushing in" without caution - is also total BS. And as far as I can see, you have provided no evidence to counter, other than to speculate on my credibility without actually knowing my actually qualifications.
But if you are saying there's a down side to this technology - sure - isnt there with anything - cars kill people - airplanes can crash - a hammer almost killed Pelosi's husband, - drugs have side effects. So is that your point - give me a break?
Isn't technology an amazing thing. I mean people will probably always be skeptical. However when in good hands and being cautious their is honestly so many great achievements that can be accomplished. Thank you RUclips, World Science Festival, and all the scientific research that is being done to help make the world a safer and better world.
Covid!
Excellent Analysis, Deployed Worldwide Through My Deep Learning AI Research Library SilentWeaponsForQuietWars
Thank You
It may inspire a few Dr. Frankenstein's with costly aspirations realized too late. It may save a lot of lives as well.
There are reasons to intervene with nature in some cases. What if you could bring back what was like love lost?...
It will destroy lives, not save lives.
Can you recall homosexuality defined as a pathological disorder? Hitler and racial hygiene? Females are intellectually inferior? Black people are not even humans? Why were alternative races defined as diseases? Humans clearly cannot be trusted, they will no doubt abuse people with it with selfish motives. You probably think that's pseudoscience, but no, they were the claims the best scientists of their day concluded, it was bad science based on confirmation bias by racists as CRISPR is bad science by ableists.
I am autistic and I don't want to be cured of the gifts that come with it, they should not have the right to change people without our consent, it is racism and discrimination.
Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution."
Evelyn Fox Keller explains:
"We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution."
The mutants behind autism offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction.
Psychologist Howard Gardner warns:
"With the coming of age of genetics, the danger magnifies. Beyond doubt we will discover genes that are important for reading alphabetical scripts; and there is already evidence that a small set of genes may be related to reading problems. As with the brain evidence, such information can be helpful for early intervention; but it could easily be used for stigmatising purposes. Indeed, it might become relevant for marriage prospects, holding a job, securing insurance, or even eugenic purposes. And no doubt, especially in our interventionist society, individuals with a genetic predisposition for reading problems will look into different kinds of genetic engineering or therapy. It is possible that such interventions will work and have no negative side effects, but it is perhaps more likely that they will have unanticipated effects. And we might even want to consider which valued human abilities - eg. spatial or pattern recognition skills - might be placed at risk were we to target our interventions specifically at reading disorders."
We can see the vast majority of so called diseases for what they are; they are discriminatory social constructions, not an intention to objectively understand human biology.
Were global warming, warmer oceans, production of epidemic diseases, climate change, increased natural hazards and more anticipated? I doubt it so I would say Howard Gardner has a good point, every time humans have tried to play God and control nature nature struck humans back with greater problems, the people trying to solve the problems are the people who caused the problems and are trying to solve those problems repeating the same mistake to cause more problems.
Since those of us you define as "genetically inferior" have abilities those you define as "genetically superior" don't have, doesn't that mean "normal" people are genetically inferior as well?
This is no different to the eugenics movement.
Lulu and Nana! 😀👍
1:18:00 👏 👏 👏 👏 👏 👏 👏 👏 👏
Brilliant. It is still taking to long.
I fu€&ing love the WSF
The basis components of life is ACTG the organic composition that has all the features of life that was created and the ones yet to come or evolve it all depends on how long the chains are and how many. All gene creation depends on the conditions and environment. So just with those basic ACTG you can create any life controlling the conditions and environment. Even new organisms can be created just by computer modelling and emulating environments. Gene engineering is just the beginning . But huge scope for furthermore. Exceptional movies thanks,.
Should come with latest developments also. Evolution is just the path of genes based on conditions.
Any dead mosquito forms a set of viruses and it is true for any animal.
Lets carefully and deliberately pursue this science. It is for the good of all mankind that we are agile and adaptable genetically. Our survival as a species may depend on it.
11:35 I had no idea Ed Sheeran was also a biologist!
I'm related to Johnston
I like this idea .. but that introduce video .. was really creepy..The last sencence tho "For better or worse every life on earth will soon be affected by our ability to reprogram the software of life" my skin was all gooseflesh
same! predictive programming...
The only way to reach your desire for eternal life and believe me that's the goal. Is to give your life to Jesus Christ. You are playing God. This research will be tested on us. You will also destroy what God created .
@@reneewallace855
These fools all occultists are elbows deep in Operation Covid
Well what if Earth already is an experiment with this and we would be in phase ... 🤔I don't know what number we would be on but I want it to where genetics that have a bit of a flaw are corrected. Diseases cured..
Maybe that was why they made something that would touch everyone's life.
this is shortly and boldly saying SATAN WORK. sadly who have no idea how dangerous and destructive this can be.
THIS IS ALL ABOUT MODIFYING GOD´S IMAGE IN US; ADDING "something better" does not mean you will be happier, means you will lose your salvation...
And here we are with the jab, Recombinant DNA nicknamed Chimeric DNA
I don't know if they know what they're doing is wrong.
51:20 Editing human genome to eradicate disease, what is the problem?
religious?
J Zerballs Nope.
Nope? The question was "What is the problem". My answer was the religious. They are always in contempt with science.
+J Zerballs I misunderstood your statement. Religious people have issues with genetic engineering as do scientists of various flavors. Genetic engineering and Pandora's box are often spoke about together.
Ha ha , for sure. GOD wrote DNA sequence and protected it with copyrights, cant break those now can you ....
Awesom
Human curiosity and the desire for evermore in all things, place us more than ever on a steep precipice overlooking...???
The future of course,belongs to those who harness advantage soonest...
Q:Can the wisdom of foresight ever approach the wisdom of hindsight?
So true..Humanity`s Curiosity ,, But curiosity liked the cat..
The Future belongs to those who have the technology ...
There must be some hindsight in foresight , as wisdom is built on experiences .
I like the way you think .
If wisdom has "hard limit", yes. Otherwise, no, hindsight will teach(teaches) you, that unless you willing to take a risk, you WILL perish.
"Can the wisdom of foresight ever approach the wisdom of hindsight?"
the answer is no, by the definition of the words, its like asking can water not be wet or apples not be fruit, the answer is no, not because of deep insight of the Universe but because of the very definitions of the words. Like finding the illusionary married bachelor, will we, probably not.
For foresight to ever approach hindsight we would need a perfect model of reality to be able to predict the future with 100% accuracy, such a state the future would be know including all of our objections to the tech and change the development immediately (which is actually none sense because with a perfect model of reality all we would need is a powerful enough computer to basically give us all the future tech as soon as it done with the calculations)
Christian Cortez I totally agree , well said.
54:22 thank you for being honest to us mam, cause currently there are a lot of hoaxes out there. claimed that they can do that and this or this but later turned out its just a bullshit
Offsprings preserve and all our Meeks? What is hunting?
so increasing the frontal lobe ( makes you very very super smart ) would make science flow mega fast..............such power though !!!
good
nice
As in the days of Noah. That turned out real well for everyone didn't it? Ridiculous.
우리는 부족한면도 있겠지만 충분히 잘하고있어 단지 살아가다 장애물을 만날뿐이야
we have so many tech companies now, but when will we start having biotech companies popping up everywhere.
CRISPER could help stop diseases like cancer, diabetes and birth defects like cleft palettes. I wonder if it could help with addiction?
Reecewe sky will always feel the bass?
$
For You have not said a WORD UNTO US? Keep watch!
1601 to 1642 thats why im not taking that shot year of 2021 my final thought
This is a Diabolical Technology!
@@bigaschwing2296 gene splicing and DNA modification with CRISPR is a TRANSHUMAN TRAVESTY. It permanently Destroys the image of God implanted in the cells of every human being and defiles the temple of God which is the body.
1 Corinthians 3:16-18
Know ye not that ye are the temple of God, and that the Spirit of God dwelleth in you?
If any man defile the temple of God, him shall God destroy; for the temple of God is holy, which temple ye are.
Let no man deceive himself. If any man among you seemeth to be wise in this world, let him become a fool, that he may be wise.
What do you have to study to this this type of job?
Cletus From the hood Molecular biology/biotechnology . I study this
How about applying it to generative cells tissue
Blowing away all aims forgotten came from?
1:21:30 👍
I don't know about this! I seen Splice!
Don't touch my food thank you.
2022 and finaly the first transplant from pig to human happened. just 6 years after this interview
I would definitely edit the hair line on the woman on the left.. it's really bothering me
Not
I love my crisp in my refrigerator...🥰
Im trying to watch this in my bio class but my sub doesn't know how to work the smart board
Splitting of the Adam/Atom ...they did it on paper, now they are seeking to do it upon the Living, surely such a grotesque trespass cannot be allowed to occur unchecked?