I'm not a medical professional but remember a very interesting time in my 20s working in a very busy OD in London...and maybe hadn't the courage or means to push on...you h have excellent delivery and clear love for the subject...jeez inhalation gases..effective but hard to measure ...a few puffs of ether would probably suffice less than 100 years ago..the PK/PD profiles of these drugs seem to be specific to a point....I guess there is a lot of presumption about these issues..Keep experimenting..
the way i imagine it with higher cardiac output being a factor of slower emergence (at least for inhalational agent) is due to a much shorter transit time during which agent is able to exude from plasma into alveoli and breathe out by the patients. the opposite is true with induction.
Is the Va:FRC ratio a simplification of the whole machine time constant which takes into account the volume of the circuit (FRC+circuit volume) and all flows (Minute ventilation + fresh gas flow) or are those seperate concepts?
My understanding is that they are separate: >>FGF : circuit volume gives rise to a time constant for the circle >>VA : FRC gives rise to a time constant for the lungs Clearly, low FGF will reduce the rate of rise of partial pressure in the FRC However, time constants refer to the rate of equilibration rather than the rate of rise Hope this helps
Dear viewer, If you found this video helpful, I suggest you also watch this one on the subject of MAC (minimum alveolar concentration). ruclips.net/video/mfrPC2b6OxU/видео.html Kind regards, Stuart
I'm not a medical professional but remember a very interesting time in my 20s working in a very busy OD in London...and maybe hadn't the courage or means to push on...you h have excellent delivery and clear love for the subject...jeez inhalation gases..effective but hard to measure ...a few puffs of ether would probably suffice less than 100 years ago..the PK/PD profiles of these drugs seem to be specific to a point....I guess there is a lot of presumption about these issues..Keep experimenting..
Yep, I love this topic!
the way i imagine it with higher cardiac output being a factor of slower emergence (at least for inhalational agent) is due to a much shorter transit time during which agent is able to exude from plasma into alveoli and breathe out by the patients. the opposite is true with induction.
Very nice , brief and helpful. Thanks
Is the Va:FRC ratio a simplification of the whole machine time constant which takes into account the volume of the circuit (FRC+circuit volume) and all flows (Minute ventilation + fresh gas flow) or are those seperate concepts?
My understanding is that they are separate:
>>FGF : circuit volume gives rise to a time constant for the circle
>>VA : FRC gives rise to a time constant for the lungs
Clearly, low FGF will reduce the rate of rise of partial pressure in the FRC
However, time constants refer to the rate of equilibration rather than the rate of rise
Hope this helps
Dear viewer,
If you found this video helpful, I suggest you also watch this one on the subject of MAC (minimum alveolar concentration).
ruclips.net/video/mfrPC2b6OxU/видео.html
Kind regards,
Stuart
the only useful thing i got from this video was the book the lecturer kept referencing to