Thanks so much for watching and posting!! This is somewhat gender and individual specific....but in general, a person begins having reduced ability to build bones around this age. However, it is different based on an individuals genetic history as well as gender. A female has a higher incidence of osteoperosis due to the effects of estrogen on osteoclast activity.
A couple of things. Wolf's law really is just the bone adapts in a manner specific to the stresses placed upon it. Now this tends to be more deposition in response to the load placed upon but it doesn't have to be. Bone adapts to the stresses placed upon it and in a manner specific to the stresses placed upon it but there's no guarantee that adaptation will be the best, most logical manner relative to the stimulus. Also, you saw that appositional growth is growth of the diameter but that is not strictly true as well. Appositional growth can theoretically occur on the longitudinal ends of the bones as well. But where would you get the osteoblasts to deposit the bone in those cases? The articular chondrocytes I have seen evidence can differentiate into bone cells though.
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis those are all good points...please keep in mind that these videos are made for beginning A&P students.. in that sense some generalizations are made to prevent the student from being overwhelmed in the topic... In addition, the information is presented in a general way to draw on the "average" person's general knowledge... Thanks for the input!
Thanks so much..i want to ask you....after appositional growth of cartilage the triggering of calcification and destruction of chondrocytes will occur directly that is true or wrong????
Yousif, The calcification process can be triggered by several factors. I will give two major ones here. (1) The deposition of cartilage in bone is the body's response to stress on that bone (Wolffs law of bone). The osteocytes will trigger the process of appositional growth where osteoblasts lay down bone. As the bone is deposited, the chondrocytes have reduced diffusion of nutrients thus dying. (2) Hormones, such as growth hormone, can trigger bone growth as well. The cells of bone growth (chondroblasts and osteoblasts) are affected by this hormone causing them to multiply and deposit bone. In addition, growth hormone causes the production of IGF-1 (insulin like growth factor) increasing the activity of these cells.
appositional growth is growth that increases the circumference of the bone to help resist stress that is placed on it. This growth is not from epiphyseal plates (growth plates) but rather the combined action of osteocytes and osteoblasts to deposit both the inorganic and organic components of the bone matrix.
Just one comment. Osteoclasts are derived from monocytes, which in turn are derived from myeloid cell line.
Hiranya,
Thank you for commenting. That is correct. The osteoclasts are derived from the myeloid cell line enabling phagocytosis for bone degradation.
Thanks so much for watching and posting!!
This is somewhat gender and individual specific....but in general, a person begins having reduced ability to build bones around this age. However, it is different based on an individuals genetic history as well as gender. A female has a higher incidence of osteoperosis due to the effects of estrogen on osteoclast activity.
Ps: my teacher said that bone peaks in mass at 30 years old. If this true? So after thirty, our bones cannot get any thicker? Thanks once again
You are welcome!!! I hope it helped you... please like and subscribe if you would...
A couple of things. Wolf's law really is just the bone adapts in a manner specific to the stresses placed upon it. Now this tends to be more deposition in response to the load placed upon but it doesn't have to be.
Bone adapts to the stresses placed upon it and in a manner specific to the stresses placed upon it but there's no guarantee that adaptation will be the best, most logical manner relative to the stimulus.
Also, you saw that appositional growth is growth of the diameter but that is not strictly true as well. Appositional growth can theoretically occur on the longitudinal ends of the bones as well. But where would you get the osteoblasts to deposit the bone in those cases? The articular chondrocytes I have seen evidence can differentiate into bone cells though.
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis fair points... please keep in mind that these videos are made for beginning A&P students... they are meant to streamline and simplify the complexities of bone growth and repair... Thanks so much for posting!
+MegaTylerDavis those are all good points...please keep in mind that these videos are made for beginning A&P students.. in that sense some generalizations are made to prevent the student from being overwhelmed in the topic... In addition, the information is presented in a general way to draw on the "average" person's general knowledge... Thanks for the input!
Thanks so much..i want to ask you....after appositional growth of cartilage the triggering of calcification and destruction of chondrocytes will occur directly that is true or wrong????
Yousif,
The calcification process can be triggered by several factors. I will give two major ones here. (1) The deposition of cartilage in bone is the body's response to stress on that bone (Wolffs law of bone). The osteocytes will trigger the process of appositional growth where osteoblasts lay down bone. As the bone is deposited, the chondrocytes have reduced diffusion of nutrients thus dying. (2) Hormones, such as growth hormone, can trigger bone growth as well. The cells of bone growth (chondroblasts and osteoblasts) are affected by this hormone causing them to multiply and deposit bone. In addition, growth hormone causes the production of IGF-1 (insulin like growth factor) increasing the activity of these cells.
Thank you prof .......you helped me :)
Extremely helpful! Thanks a lot !
What about zone of reserved cartilage ?
Awesome video!!
thank you so much ! :)
You are very welcome! I am so glad that it helped you.
What about the zone of lacroix and the growth plate progenitor cells? Please check out NaturalHeightGrowth and Height Quest to share your thoughts.
Thanks you
sir. wt is appositional growth or surface accretion
appositional growth is growth that increases the circumference of the bone to help resist stress that is placed on it. This growth is not from epiphyseal plates (growth plates) but rather the combined action of osteocytes and osteoblasts to deposit both the inorganic and organic components of the bone matrix.