Bone remodeling and repair

Поделиться
HTML-код
  • Опубликовано: 8 фев 2025
  • What is bone remodeling and repair? Bone remodeling is when old, brittle bone tissue is removed or resorbed and gets replaced by new bone tissue. Remodeling also occurs when reshaping your bones after a fracture or when repairing micro-cracks which form during ordinary activities, especially when your bones are under stress, like after lifting heavy weights. Find our full video library only on Osmosis: osms.it/more.
    Join millions of current and future clinicians who learn by Osmosis, along with hundreds of universities around the world who partner with Osmosis from Elseiver to make medical and health education more engaging and efficient. We have unparalleled tools and materials to prepare you for success in school, on your board exams, and as a future clinician. Sign up for a free trial at osms.it/more. If you're interested in exploring an institutional partnership, visit osmosis.org/educators to request a personalized demo.
    Follow us on social:
    Facebook: osms.it/facebook
    Twitter: osms.it/twitter
    Instagram for med: osms.it/instagram
    Instagram for nursing: osms.it/ignursing
    TikTok: osms.it/tiktok
    Linkedin: osms.it/linkedin
    Our Vision: Everyone who cares for someone will learn by Osmosis.
    Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here: osms.it/mission
    Medical disclaimer: Osmosis from Elsevier does not provide medical advice. Osmosis from Elsevier and the content available on the Osmosis from Elsevier properties (Osmosis.org, RUclips, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed healthcare provider. Always seek the advice of a physician or other qualified healthcare professional with any questions you have regarding a medical condition.
    © 2024 Elsevier. All rights reserved.

Комментарии • 195

  • @alfathrahagika7226
    @alfathrahagika7226 4 года назад +149

    why this gave me more understanding than my college..i love it

    • @kashifkhan7379
      @kashifkhan7379 3 года назад +13

      Focused on lecture rather than Girls 😂😂😁

    • @This_or_Thatx1
      @This_or_Thatx1 3 года назад +1

      Willl my bone density will grow after quitting drugs? I am 23+.

    • @amnafayyaz6768
      @amnafayyaz6768 2 года назад

      Because you are fool 🤣

  • @senankavanagh2382
    @senankavanagh2382 3 года назад +40

    Great video. ties everything together nicely. Decided to review bony remodelling today and fascinating what you can pick up again on revision. Initially when learning about bony remodelling I never really thought about the significance of RANKL , but with drugs such as Prolia , a RANKL inhibitor , it becomes obvious as to why the fundamental understanding of the physiological processes is vital to clinical practice with associated pathological states such as Medication related oseteonecrosis of the jaws. Many thanks.

  • @Dhruvrajpal-x2y
    @Dhruvrajpal-x2y Год назад +13

    Finally understood the mechanism after 5 retake. love this type of resource, really insightful and articulate.

    • @osmosis
      @osmosis  Год назад +1

      We're glad it helped, Dhruv! 🙏🏼

  • @evakhwaiss7484
    @evakhwaiss7484 3 года назад +36

    I've searched more than 1 hour for a video like this, thank you so much 😍 this sums up everything i want about bone tissue 👏

    • @osmosis
      @osmosis  3 года назад +2

      Hi Eva, Glad it was helpful!

    • @abel6298
      @abel6298 Год назад +1

      Read your bible! (KJV, preferably) ♥‎

  • @bayannasseral-harrasi6089
    @bayannasseral-harrasi6089 Год назад +34

    Bone remodeling in short:
    -Osteoblast release M-CSF & RANKL → Convert monocytes into osteoclasts → ↓ Bone mass
    -Osteoblast also release Osteoprotegerin (OPG) → OPG will inhibit RANKL → ↑ Bone mass

  • @rasheshdas
    @rasheshdas 4 года назад +7

    The illustrations are fabulous

  • @degodaniyt6557
    @degodaniyt6557 2 года назад +6

    I would have loved to see more infromation about hormones and their influence on bone remodelling, such as the osteolytic effect of cortisol and such. An all-in-one video of what hormones affect bone remodelling.

  • @uhlezza
    @uhlezza 4 года назад +12

    This was really helpful plus the illustrations are adorable!! Thank you so much.

  • @mshaik435
    @mshaik435 3 года назад +4

    Osmosis makes med school easy♥️love this channel. So accessible

    • @osmosis
      @osmosis  3 года назад

      Yey! We're glad to be of help to your medical journey! If have time, feel free to sign up for a free trial at osmosis.org so you can access more of our video library and other study features. 😊

  • @infiredpumpkins1970
    @infiredpumpkins1970 4 месяца назад

    It's crazy how well osmosis explains stuff 😭😭 life saver

    • @osmosis
      @osmosis  4 месяца назад

      We're glad to help! ❤️

  • @mikhailkushadiwijaya1027
    @mikhailkushadiwijaya1027 3 года назад +12

    Simple yet deep and well explained. Thanks a lot. Please make more animationlike this. I really appreciate it. Gbu all team!

    • @osmosis
      @osmosis  3 года назад

      Thank you Mikhail for that wonderful feedback!

  • @Realmadridforever714
    @Realmadridforever714 3 года назад

    One of the best video on bone remodeling

    • @osmosis
      @osmosis  3 года назад +1

      Wow, thanks for that feedback!

  • @melindaaa1404
    @melindaaa1404 2 года назад +2

    This is the perfect video for this subject. Thank you so much!

    • @osmosis
      @osmosis  2 года назад

      Glad you think so!

  • @heathenwizard
    @heathenwizard 3 года назад +6

    Great visuals and wonderfully concise and explanatory! Thanks so much!

    • @osmosis
      @osmosis  3 года назад +1

      You're very welcome! Thanks for letting us know!

  • @sarahesse2979
    @sarahesse2979 Год назад +1

    Thank you for sharing. Please we would love to see more videos like this

  • @katharina6865
    @katharina6865 2 года назад +3

    Wow, this is really informative. Thank you! I lost 2 Parathyroids after a messed-up operation. Still don`t know how to deal with this, but trying and learning. 😰

    • @osmosis
      @osmosis  2 года назад +1

      Sorry to hear that. Katharina. We hope you're doing better now. 🙏🏼

  • @cpbeauvoir
    @cpbeauvoir 11 месяцев назад

    Watching this on my way to my test. Thank you

    • @osmosis
      @osmosis  11 месяцев назад

      We hope it went well! 🙏🏼

  • @ahmedbasim7368
    @ahmedbasim7368 15 дней назад +1

    I love you soo much , more than you could imagine osmosis ❤❤❤❤❤❤

    • @osmosis
      @osmosis  13 дней назад

      Thank you! 💕

  • @LuanTran
    @LuanTran 3 года назад +1

    What a vivid way to present such hard topic. Thanks a lot !

    • @osmosis
      @osmosis  3 года назад

      Thanks for your wonderful comment! 🥰

  • @hmzzrg5045
    @hmzzrg5045 Год назад +3

    I think there is a mistake at 2:41. Myeloid progenitor cells come from hematopoietic stem cells, not lymphoid stem cells.

    • @osmosis
      @osmosis  Год назад +2

      Thanks for pointing this out! Our team will be reviewing this information and update the video as needed. 🙏🏻

  • @kuengatshomo7396
    @kuengatshomo7396 Год назад

    Wow thats so helpful...Thanks alot. In the midst of confusion and infodemic, its like a hopeful rays.

    • @osmosis
      @osmosis  Год назад

      Glad it was helpful! 💫 🥰 💖

  • @MA-fd6kg
    @MA-fd6kg 4 года назад +2

    Great video! Helped me a lot!

  • @ADAPTATION7
    @ADAPTATION7 3 года назад +3

    Parathyroid gland stimulates osteoclasts (not osteoblasts) for bone resorption to occur. Small mistake at 5:05.

  • @DrDY-us4rg
    @DrDY-us4rg 4 года назад +3

    That was exactly what was needed

  • @maymansourian7417
    @maymansourian7417 3 года назад

    Another great video by the Osmosis Team! Thank you!

    • @osmosis
      @osmosis  3 года назад

      Thank you too! 🙏🏼

  • @MinhNguyen-li2eb
    @MinhNguyen-li2eb 3 года назад

    Amazing. Now i remmeber the core of a complicated process in our body. TKs a lot

    • @osmosis
      @osmosis  3 года назад +1

      Glad to hear that, Minh! ❤️

  • @foramsanghavi9328
    @foramsanghavi9328 2 года назад

    That's wonderfully explained..Made understanding very clear just in 5 min..
    Thank you so much

    • @osmosis
      @osmosis  2 года назад +1

      Glad it was helpful, Foram! ❤️

  • @kooter6136
    @kooter6136 3 месяца назад

    At 50 years old I started playing basketball again almost everyday. I had a lot of bone pain in my shins - upper tibia. They felt as if they were hollowed out through time and now they were bearing too much stress. I didn't give up, kept playing but I was scared it would lead to some injury. Amazingly, after a while the pain went away. I guess this is what was happening, very interesting! From the start of it all it was my feet and ankles at first, then it moved up to my knees, then hips. Now, I have shoulder pain. It feels like a rotator cuff problem but going at it playing basketball doesn't seem to help so far. Resting it and altering my sleeping position has helped some but it feels like I have hit the limits of my age unfortunately.

  • @khanhthita2996
    @khanhthita2996 5 месяцев назад +1

    as a medical student, I admire and appreciate all your work

    • @osmosis
      @osmosis  5 месяцев назад

      Thank you! 🥰

  • @Vikrant-7812
    @Vikrant-7812 Год назад +1

    I'm gonna send this video to my professor 💀✌️

  • @charmimgshahnaz7455
    @charmimgshahnaz7455 4 года назад

    Dear Osmosa,,, please make a video about closed fracture.. thanks a lot.

  • @aventadorgamer1575
    @aventadorgamer1575 3 года назад +1

    Medical college life is easier with osmosis! 💗💗

    • @osmosis
      @osmosis  3 года назад

      Glad to be of help! 😊

  • @fevenre4969
    @fevenre4969 3 года назад +1

    Very brief vidio......Thanks alot

  • @marysakala1079
    @marysakala1079 2 года назад

    Very clear and straight forward

    • @osmosis
      @osmosis  2 года назад

      Thanks, Mary! 👍🏼

  • @KhadigalMohamed
    @KhadigalMohamed Год назад +1

    Great ❤❤❤❤❤🥳🥳

  • @mariamriaz2311
    @mariamriaz2311 2 года назад +25

    Where's repair???

    • @peednas711
      @peednas711 7 месяцев назад

      It starts at 4:20

  • @ramokunupisekgwaila5033
    @ramokunupisekgwaila5033 2 года назад +1

    Well explained 👏👏👏, thank you so much 🙏

    • @osmosis
      @osmosis  2 года назад

      Glad you think so, Ramokunupi! 🥰❤️🙏🏼

  • @khushishah2130
    @khushishah2130 4 года назад

    ❤️❤️.. plz make a video on osteoporosis

  • @ayamohammed7753
    @ayamohammed7753 Год назад

    Great explanation ma sha Allah!

  • @nothing_fancy692
    @nothing_fancy692 10 месяцев назад

    Thank you!!! It makes so much sense now!

    • @osmosis
      @osmosis  10 месяцев назад

      Glad to help! 😊

  • @paltrygorilla9151
    @paltrygorilla9151 4 года назад +1

    Thanks Bro! this really helped me.

  • @dunyaimanova9207
    @dunyaimanova9207 2 года назад

    the best explanation 😍

    • @osmosis
      @osmosis  2 года назад

      Thanks, Dunya! 💕

  • @dhangejr
    @dhangejr Месяц назад

    So I have a question is there anything I can take to help my body strengthen my bones? I did have a mild fracture and a lot of people were saying to take vitamin D, calcium and vitamin C. But after watching this video on doing some more research, I’ve determined that’s not a great idea.

  • @wendyfer735
    @wendyfer735 3 года назад

    Thank you!

  • @CHRISGURJAR
    @CHRISGURJAR 2 года назад

    Awesome explanation. Loved it.

    • @osmosis
      @osmosis  2 года назад +1

      Thanks, Chris! 😊

  • @ranch-ng1gv
    @ranch-ng1gv Год назад

    I wish my actual lecture was that easy with less deatails :(

  • @AyaSaad-vo8ls
    @AyaSaad-vo8ls 4 месяца назад

    Best summary ❤

    • @osmosis
      @osmosis  4 месяца назад

      Thanks! 😊

  • @navyashreedegowl9352
    @navyashreedegowl9352 3 года назад

    U ppl.arw.doing such a great teaching
    ..thanks a lottt

    • @osmosis
      @osmosis  3 года назад

      Hi Navyashree, thank you, we're glad you find our videos useful! :)

  • @thomasbays8292
    @thomasbays8292 Год назад

    My daughter had PAO surgery. The coverage is good no doubt. She still has pain and is very thin, could bone remodeling be an issue?

  • @gauravgupta174
    @gauravgupta174 2 года назад

    When the bone is getting remodeled due to stress fracture , does it add 2-3 inches in height growth . When fully recovered

  • @azouz5675
    @azouz5675 3 года назад

    why there is resorption in one side and the deposition in the other side not in the same side ?

  • @itxmfahadkhan
    @itxmfahadkhan 2 года назад

    You are a life saver ❤️

    • @osmosis
      @osmosis  2 года назад

      Always glad to help, Muhammad! 🥰

  • @Bassman7608
    @Bassman7608 2 года назад

    @5:03 I think you’re mistaken. Shouldn’t the osteoclast be reabsorbing bone to release calcium in the bone?

    • @osmosis
      @osmosis  2 года назад +1

      Hi Kevin! Thanks for pointing this out. We've notified our team about this so they can have the information reviewed. 😊

  • @wifaqjaborialbazy-4405
    @wifaqjaborialbazy-4405 Год назад

    excellent job

    • @osmosis
      @osmosis  Год назад

      Many thanks! ❤️

  • @ruveydalipa
    @ruveydalipa 9 месяцев назад

    This is so good but i dont know english well so it was hard to understand😭😭 but tysm anyways that helped a lot🥹🫶

  • @rasheshdas
    @rasheshdas 4 года назад

    Thank you very much

  • @grant4360
    @grant4360 2 года назад

    I think there is a small mistake, yellow bone marrow does not produce blood cells as was indicated in the video. That is actually red bone marrow typically found in the epiphysis

    • @osmosis
      @osmosis  2 года назад +1

      Thank you so much for bringing this to our attention, Grant! I will be sure to pass this along to my colleagues on the Content Team so they can check the details with our Chief Medical Officer. 😊

  • @hananmohamed9302
    @hananmohamed9302 2 года назад +1

    great vid

    • @osmosis
      @osmosis  2 года назад +1

      Thanks, Hanan! 😊

  • @eugenunesdemoraes2398
    @eugenunesdemoraes2398 Год назад

    Great video, thank you

    • @osmosis
      @osmosis  Год назад

      You're welcome, Euge! 🥰

  • @lynnlive21
    @lynnlive21 4 года назад +2

    Thank u! ♡

  • @nihalgaber3403
    @nihalgaber3403 3 года назад

    I have a question please regarding Wolff's Law: if we say that
    Applied pressure results in bone resorption, while applied tension results in bone formation.
    is that correct or not?

  • @dr_blueman
    @dr_blueman Год назад

    Thank you. ❤

    • @osmosis
      @osmosis  Год назад

      You're welcome 😊

  • @Chuckbgd
    @Chuckbgd 4 года назад

    thx! it help me a lot

  • @francesca186
    @francesca186 Год назад

    hi, could you add the bibliography used to make this video? it was so useful to me and i'd like to read sources too

    • @osmosis
      @osmosis  Год назад

      Hi Francesca! You may access this information when you hop on osmosis.org! Please feel free to sign up for the 7-day free trial (no card needed) anytime 😊

  • @mahuubao
    @mahuubao 2 года назад

    Excellent ... well done ...

    • @osmosis
      @osmosis  2 года назад

      Thank you, Mahu! 🙏🏼

  • @wypy817
    @wypy817 3 года назад

    I just failed my exam because i never prepare for ortho sub the intro was so boring in my university lecture i need to start with this ✊🏻🤞🏻 wish me luck everyone i m gonna start studying this video give me so much hope i find it it very interesting and its very easy to understand this😁

    • @osmosis
      @osmosis  3 года назад

      Hi Pitchet! You can rock this exam! If you can, you may sign up for a free trial at osmosis.org so you can access our entire video library and study resources to help you ace your exam. This might help! We won't be asking for your bank details or anything, so no worries. 😊

  • @arshishamim4064
    @arshishamim4064 3 года назад

    nicely explained :)

  • @shelbyrodrigues
    @shelbyrodrigues 6 месяцев назад

    can you please make a video on the 2 types of bone ossification and the stages for each!!! I canot find any animations on youtube

    • @osmosis
      @osmosis  6 месяцев назад

      Thanks for your recommendation! Our team will be taking this into consideration. Have a wonderful weekend! 💖

  • @arizarichie9446
    @arizarichie9446 2 года назад

    how long is it ? how long the process go ?

  • @alikadhim4546
    @alikadhim4546 4 года назад

    Amazing ♥️♥️♥️♥️ thank you very much

  • @Kiran.2020
    @Kiran.2020 3 года назад

    You are the best ❤️

    • @osmosis
      @osmosis  3 года назад

      Aww.. thank you Kiaan! ❤️

  • @sachinrathore28
    @sachinrathore28 4 месяца назад

    Wow amazing explanation

    • @osmosis
      @osmosis  4 месяца назад

      Thank you! ❤️

  • @jayarramos2300
    @jayarramos2300 4 года назад

    How about left humerus? How many months it takes before healing?

  • @EkilRevolution
    @EkilRevolution 2 года назад

    What do you think about bonesmashing?

  • @rethijja3331
    @rethijja3331 3 года назад

    This is amazing

  • @munishgupta2226
    @munishgupta2226 3 года назад

    Excellent presentation , but as far as I know osteoclasts doesn't produce COLLAGENASE , it is produced by osteoblasts actually , bone resorption by osteoclasts at it's clear zone (at ruffled borders) mediated by carbonic anhydrase , secondly it pump out hydrogen ions( after CO2 hydartion - H2CO3 formation - breakdown into Hydrogen and carbonate ions -then pump out hydrogen ions) which lowers pH , lysis of collagen in acidic media , which leads to bone resorption , Plz tell me if I m wrong

  • @GuidetteExpert
    @GuidetteExpert 10 месяцев назад

    Are these cytokines that these cells use to signl or use as a communication to start og stop a process?

  • @1cloudshinobi
    @1cloudshinobi 10 месяцев назад

    What is the duration of this process

  • @maja0247
    @maja0247 Год назад

    Thank you so much this is amazing

    • @osmosis
      @osmosis  Год назад

      You're so welcome! 💖

  • @laurenndance
    @laurenndance 4 года назад +2

    Pretty helpful! Thanks!

  • @sofi11
    @sofi11 18 дней назад

    So helpful!

    • @osmosis
      @osmosis  13 дней назад

      Glad it was helpful! 💖

  • @LiamGarthwaite-j1q
    @LiamGarthwaite-j1q 5 месяцев назад

    Does bone remodelling make the bone stronger and bigger like a muscle

  • @sufias1459
    @sufias1459 3 года назад

    Perfect👌Tnks✨🌸

  • @Medipharma-hu4tr
    @Medipharma-hu4tr 7 месяцев назад

    Thank you.....very usefull video

    • @osmosis
      @osmosis  7 месяцев назад

      Welcome! 😊

  • @btsismybias8332
    @btsismybias8332 2 года назад

    Thanks a lot !!!

    • @osmosis
      @osmosis  2 года назад

      We hope our video helped! 🥰

  • @mehsudmedicos8768
    @mehsudmedicos8768 2 года назад

    very appreciable

  • @halobium3513
    @halobium3513 3 года назад

    excuse me but do you have a video explaining mechanism of healing of bone's fracture?

  • @llostudio4278
    @llostudio4278 2 года назад

    Really nice

    • @osmosis
      @osmosis  2 года назад

      Thank you! 🥰❤️🙏🏼

  • @UHFStation1
    @UHFStation1 2 года назад

    This didn't really explain how the bones know what shape they're supposed to be. I am particularly interested to know why spinal stenosis doesn't reverse itself relieving pressure on the spinal cord.

  • @rosiefans863
    @rosiefans863 Год назад

    Understand thanks. A lot

    • @osmosis
      @osmosis  Год назад

      Happy to help 🙏🏼

  • @honeybadger1621
    @honeybadger1621 2 года назад

    what if person diabetic? how will heal

  • @mike.m4621
    @mike.m4621 4 года назад

    I had 12 years ago a femure fracture very ugly caused by a tumore. I had surgery ofcourse the doctor said he clean everything there very good and he put me a metal plate wich I still have now and than I had the chimioterapy treatment. After 3 years I started to go slowly to gym and workout slowly but still even now after years I still cannot do the exercises for legs I did before the fracture because some pain during workout. You think the femur after this damage has healed properly? I will like your opinion also. Thank you

  • @maryambukhari7635
    @maryambukhari7635 2 года назад

    Amaaaaazing !!!!

    • @osmosis
      @osmosis  2 года назад

      🙌🏼 💕 ✨

  • @swagMan253
    @swagMan253 4 года назад

    Does this process take place in the skull bones like the jaw or cheekbones?

  • @BhaskarDrukGiri0688
    @BhaskarDrukGiri0688 Год назад

    Awesome

  • @StiffAftermath
    @StiffAftermath 3 года назад

    So...is bone death reversible?

  • @sitiulfaturrizqa3555
    @sitiulfaturrizqa3555 3 года назад

    woow I love this one, thank for amazing video :)))

    • @osmosis
      @osmosis  3 года назад

      Glad you like it, Siti! 🙌🏼

  • @arh1511
    @arh1511 4 года назад +1

    Great

  • @Omar_11234
    @Omar_11234 4 года назад

    amazing❤❤❤❤❤❤❤❤❤

  • @QulyneMokaya
    @QulyneMokaya 11 месяцев назад

    This is nice