Lac operon
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- Опубликовано: 2 фев 2025
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Overview of gene regulation in the Lac operon. Discussion of CAP, cAMP, lac repressor and allolactose in regulation of lac operon.
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This helps me understand the LAC OPERON very well without bordering reading whole Campbell 10th edition textbook.
I feel ya bro =)))) 2016-2017 students still have the sameeee problem
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2019-2020 students still have the same problem
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Thanks for this video! Great explanation! One thing to add for those who are curious is that when glucose levels are high the RNA-polymerase will bind to a promoter (not the same promoter) and transcribe a gene that codes for a repressor so that in turn can bind to the operator and stop transcription of the beta-galactosidase (LacZ) since we don't need to metabolize lactose.
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This is so much better than trying to read from the Lehninger Principles of Biochemistry textbook. I read every word about the lac operon, but did not understand any of it until this video. THANK YOU
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Unbelievably helpful, took a concept that I wasn't understanding from lecture and made it make so much sense
This was one of the best explanations of the lac operon I've heard
Especially that you explained the cAMP was very helpful. I'm german and I didn't find anything about it in german videos. Thank you!
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Learned more in 1 video than an entire week of class
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My professor spent two lectures trying to explain this and we were all still blank at the end of it. Thank you so much
I think I’ve watched this video minimum ten times over the course of my degree
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You cracking up made this a very enjoyable learning experience for me. Thanks
SO GOOD, EXPLAINS BETTER THAN ANYONE ELSE COULD
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Thank you so so so much, I didn't understand the Lac operon until now. You saved me!!!
I’ve been trying to understand this for weeks 😂 thank you
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I would like to point out that the Operon is activated when glucose is absent and lactose is present. If glucose and lactose are present, the repressor would still remain bound
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Man! this is AMAZING and much more helpful than my professor and books
Thank you so much for helping me understand how Lac operon works!! I didn't even understand the mechanism when my professor told us in my native language
Amazing set of videos... easy to understand and very helpful...
Thanks a lot for this video and also the one on tryptophan. I was understanding nothing about this genetic expression regulation systems, and you made it very clear, I feel I completely got it. You explain very well and the video also helps
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This means if you are lactose intolerant and still want to drink milk, do it when you have'nt eaten anything all day.
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Amazing explanation❤
To sum up, when there is no glucose and lactose is present, the catabolite activator protein with high cAMP will bind to the CAP site, therefore enabling transcription(the body needs energy) while if there is glucose and lactose, the system prefers glucose over lactose and will not transcribe. The catabolite activator protein will not bind since it already has a lot of cAMP, here the lac operon acts as an regulatory sequence of gene responsible for protein synthesis. The glucose inhibits the production of cAMP(cAMP are derivatives of ATP) which makes sense since there is already a lot of energy.
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my professor said lac operon is not turned on in presense of glucose until glucose has been used up?
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thank you so much for letting me understand
So you lack the lac operon
lol good one!
well, bacialy, no... the operon found only in prokaryotic...
That means we all lack the lac operon
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Thank you so much, it was really helpful.
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so cAMP can be counted as an 'inducer' or is it an exception?
My microbio professor warned me not to use this video as a resource to study, she says its wrong. Khan academy is a good resource but this particular video may not match some undergrad classes. Viewer beware!
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Whats the basic function of lactose in the functioning of this operon
where does the allolactose come from?
Where does Lac l fit into this diagram?