Coomassie Brilliant Blue Dye - the science of SDS-PAGE staining

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  • Опубликовано: 25 дек 2024

Комментарии • 23

  • @chen-hsuanchiu3265
    @chen-hsuanchiu3265 2 года назад +5

    Very informative and I like the energy you share in the video!

  • @mahdis.the.curious
    @mahdis.the.curious Год назад +1

    I love you for making this video. you're a true angel, please keep making these useful videos! thank you, thank you, thank youuuuu!!!!

  • @MES-S
    @MES-S Год назад

    Thank you for sharing a wonderful information

  • @muhammadkaleem4251
    @muhammadkaleem4251 Год назад +1

    Bravo. Super helpful. Thank you so much for making this video :) Thumbs UP :)

  • @jandecoole5687
    @jandecoole5687 2 года назад +1

    very clear and correct explaination. thanks alot

  • @muhammadkaleem4251
    @muhammadkaleem4251 Год назад +2

    I have a question: What if we destain too much and the bands are too faint to be visualized, can we restain the gel with Coomassie and then destain again?

  • @Darcy2531
    @Darcy2531 2 года назад

    This was super helpful!! Can you tell why we take the ratio of absorbance 590/450 while performing Bradford assay?

    • @thebumblingbiochemist
      @thebumblingbiochemist  2 года назад

      Thanks! You take the ratio because it allows you to kinda normalize for background and make the standard curve linear: www.ncbi.nlm.nih.gov/pmc/articles/PMC3164080/

  • @stefanodecler149
    @stefanodecler149 Год назад

    Great explanation and so complete, thanks :) I have a question: How much time do you suggest to stain with R-250?

    • @thebumblingbiochemist
      @thebumblingbiochemist  Год назад

      Thanks! Probably like 20 min or so - longer if you need more sensitivity but then the destain takes longer too! Microwaving can help

  • @MarianaAguilarMorales
    @MarianaAguilarMorales Год назад

    can you share the volume of staining solution used and the time used at the microwave? thanks!

  • @khoinguyenlehoang6000
    @khoinguyenlehoang6000 2 года назад

    thank you very much!

  • @morgul_r3420
    @morgul_r3420 2 года назад +2

    LMAO I love this intro. HAHAHA

  • @qayyumshehzad3412
    @qayyumshehzad3412 2 года назад

    very informative, thank u