Zinc finger motif

Zinc finger motif - This lecture explains about the structural motif named zinc finger. It explains the structure and role of zinc finger motif in proper functioning of DNA and RNA binding proteins like transcription factors.
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Thank you for watching

[@akhilraaj]

I’m a doctor and I come across your videos all the time on various topics but never watched them because I never thought your videos will cover them comprehensively. Damn boy I was wrong, you are really good.

[@shomusbiologyofficial]

It's a pleasure to know that you liked my lectures

[@mridhusharma9907]

Sir, I like ur other videos but I am sry this did not go well with me. It seems to crude. Some important information was missing like it binds in major groove and contacts three bp, It's binding with cys and his, etc

[@ivankuzko7037]

Thank you so much from 1 faculty of medicine of Charles university in Prague!)))

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@drnamsoon]

Thank you so much i am here just for concept becz this is most repeated ospee of my tomorrow exam we will see if this question repeat again thanks 👍

[@shomusbiologyofficial]

All the best for future career

[@VicbengtPL]

Love your videos brother, you are doing a great job! Thanks!

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@nothingggg656]

Thankyou so much sir👍🏻♥️

[@shomusbiologyofficial]

You're welcome

[@dipteshking]

helpful video , but please provide complete information about the topic before giving the applications (where can be used) i hope applications we think of right at that moment . you have not described the structure neither said anything about 2cys and 2his. its just a suggestion please dont take it otherwise. thank you

[@georgiacohoon2513]

this was so useful! thank you so much :)

[@shomusbiologyofficial]

You're welcome

[@tutku535693]

Thanks for your all worthy efforts, i established every part of information you explained along the video clearly, well appreciated :)

[@misstaniamaryam]

Brilliant, thank you for making it easy to understand!

[@shomusbiologyofficial]

You're welcome

[@-_-ok9550]

thankyouuu

[@shomusbiologyofficial]

You're welcome

[@anag2749]

you're a great descriptor .Thanks

[@shomusbiologyofficial]

+Ana G you're welcome

[@ayaqz3144]

thank you man

[@shomusbiologyofficial]

You're welcome

[@muhammedyousafk4115]

Thankyou sir❤

[@shomusbiologyofficial]

You're welcome

[@kainatrehman7384]

Thanku soo much sir.. Plz make a video on targeted drug delivery on mice models against cancer...plz

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@red8527]

So...I have heard the term Zinc Finger Nuclease.
That should be a nuclease enzyme with a zinc finger motif which we can artificially modify so that it attaches to a specific region on the gene & makes a cut??

[@richadas171]

Zinc finger nuclease and zinc finger motif...are they same??

[@samrakhan4408]

This helped so much!

[@attulurivenkatabadarinath1044]

Nice explanation, good

[@Brighterworld5827]

Sir fos and Jun have zn binding domain ??

[@thejjm59]

I love you

[@vitthal_donadkar]

This video was wonderful. it cleared many basic concept.
thank u sir....
sir plz make video on "Fermentation kinetics"

[@kolhapurkarpatil]

More details one can get in pathfinder

[@beautydutta2034]

Can you tell me the chapter name in pathfinder book

[@himanshunainwal8939]

@@beautydutta2034 161 page number from second book...

[@beautydutta2034]

@@himanshunainwal8939 sorry I didn't got zn finger here ..it will be better if you say the chapter

[@himanshunainwal8939]

@@beautydutta2034 molecular genetics -- after eukaryotic transcription

[@beautydutta2034]

@@himanshunainwal8939 finally got.. thanks for your response

[@johntindell9591]

Thanks a lot.

[@shomusbiologyofficial]

You're welcome

[@chanchalkumari2503]

Nice explanation

[@triptimehra5940]

how does the fusion protein helps in regulating the transcription process ?

[@ajaydastp3304]

sir please conduct a class about protein domains and motifs separately

[@shomusbiologyofficial]

It's already there in my channel

[@surendraprasadsah7026]

A lot of info is missing

[@knowledgejunction1643]

Niceeeeee👍👍👍

[@akshayavidhya9325]

thanks sir

[@salmanzaibkhan7457]

Is there any lecture of talens?

[@JuhiMittal]

ty so much

[@vermasona2820]

Sir, transcription start when polymerase enzyme bind to tha promotr site .so in these case we dont required poymerase enzyme? Plz tell me because i'm confused about this😔

[@AlisonFujii14]

Why does the histidine and the cysteine associate with the zinc? Wouldn't those side chains not want to be near a positively charged ion like Zn2+?

[@dsev13]

My guess would be that histidine and cysteine are uncharged at neutral pH and are Lewis Bases, meaning they have an extra lone pair of electrons, and since the bond with Zn in these kinds of organometallic bonds are usually coordinate covalent, Zn requires an electron donor.

[@mshisha]

Thank you

[@biologicalresearch5836]

There is no alternative of yours on RUclips

[@didier4529]

Bright man

[@doaaaldabibaaa9200]

I really love u

[@shomusbiologyofficial]

Thank you

[@sheetaldahiya94]

*Thank* *you* *sir* ...please make a video on beta turn 🙏😊

[@swatiSingh-xr7xq]

Sis phle se hi uploaded h beta turn PR video

[@sheetaldahiya94]

@@swatiSingh-xr7xq okay...thanks for informing.....but mujhe nahi mil raha.....please send link 🙏😇

[@rajeshnaik9346]

thanks

[@kumarpolimera9565]

How can we modify the Zn finger n how can we add that to a biological system sir

[@rishimaborah9956]

Sir, can you please upload videos of zinc finger nucleases and TALENS as well?

[@rishimaborah9956]

It will be quite helpful! Since there are less videos in this topics. Thank you.

[@shomusbiologyofficial]

Coming soon

[@rishimaborah9956]

@@shomusbiologyofficial Thanks!

[@debadattapanda5829]

Sir, what is the signifucance of fusion protein in this & does this mean that we can modify it

[@TheIncredibleChowdhury]

You are a life saver dude... :)

[@ananyabanerjee4758]

please do a class on TALEN

[@shomusbiologyofficial]

Yes I will do that soon

[@ayezabhat5026]

thanku

[@shomusbiologyofficial]

You're welcome

[@mahadehassan5072]

can i get bacterial motif please

[@mehreensaigal4343]

Please make a series of protein-dna interaction and methods :)

[@shomusbiologyofficial]

Okay

[@the_explorer_anje8243]

Sir plz do not repeat same things and you could add more info

[@debashishadhikary9030]

Probably. Due to zinc finger transcription I went bald all over body i.e. alopecia Universalis.

[@MultiSim89]

U sir are the man lol

[@imrocknreeling]

Zink

[@cerenesen7776]

turkish translate please!!!!!!!!!!!

[@marlonmillard4277]

zn 2+

[@yusufates885]

Tuuutori yal lol

[@trexsbp409]

Amateur

[@WilldabeastFTW]

bad