Hey Chad quick question about the reactivity of LAH. How come when reducing a carboxylic acid with LAH the acidic hydrogen does NOT get deprotonated, and the reaction still produces a primary alcohol, whereas a Grignard reagent reacting with a carboxylic acid will just deprotonate the acidic hydrogen? I thought the hydride ion from LAH and carbanion from a Grignard react similarly in that they are both a strong nucleophile and base. Thanks.
thank you for being the best chem youtuber. You are carrying me in chemistry
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Hey Chad quick question about the reactivity of LAH. How come when reducing a carboxylic acid with LAH the acidic hydrogen does NOT get deprotonated, and the reaction still produces a primary alcohol, whereas a Grignard reagent reacting with a carboxylic acid will just deprotonate the acidic hydrogen? I thought the hydride ion from LAH and carbanion from a Grignard react similarly in that they are both a strong nucleophile and base. Thanks.
Thanks teacher😊
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Got a test tomorrow. Thank you
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Hy
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Why we need to use NaBH4 or LiAlH4, but not LiBH4 or NaAlH4? Thank you.
Correct me if I am not wrong, it is because they are reducing agents
reduction with Li/ liq NH3 and PtO2? For us in pharm school