Nerve Impulse

A nerve impulse is the electric signals that pass along the dendrites to generate a nerve impulse or an action potential. An action potential is due to the movement of ions in and out of the cell. It specifically involves sodium and potassium ions. They are moved in and out of the cell through sodium and potassium channels and sodium-potassium pump.
Conduction of nerve impulse occurs due to the presence of active and electronic potentials along the conductors. Transmission of signals internally between the cells is achieved through a synapse. Nerve conductors comprise relatively higher membrane resistance and low axial resistance. The electrical synapse has its application in escape reflexes, heart and in the retina of vertebrates. They are mainly used whenever there is a requirement of fast response and timing being crucial. The ionic currents pass through the two cell membrane when the action potential reaches the stage of such synapse.
The axon or nerve fibres are in the form of a cylinder wherein the interior of the axon is filled with axoplasm and the exterior is covered with axolemma. The nerve fibres are immersed in ECF. The solution is in the ionic form that is present in axoplasm and extracellular fluid or ECF.
Outside the axon, the negatively charged chloride ions are neutralized in the presence of positively charged sodium ions. Negatively charged protein molecules are neutralized in the presence of potassium ions within the axoplasm. The membrane of a neuron is -ve inside and +ve outside. Resting potential would be the difference in charge. The difference in charge might vary from seventy to ninety millivolts, as a result, the membrane would be polarized. Sodium potassium pump operates to keep resting potential in equilibrium.
The pump is placed on the axon membrane. Now the potassium ions are pumped from ECF to axoplasm and sodium ions are pumped from axoplasm to ECF.
The sodium-potassium pump stops operating when a stimulus is applied to a membrane of a nerve fibre. The stimulus could be either electrical, chemical or mechanical. The potassium ions rush outside the membrane and sodium ions rush inside the membrane as a result negative charges are present outside and positive charges are present inside.
The nerve fibres are either depolarized or they are said to be in the action potential. The action potential travelling along the membrane is called the nerve impulse. It is around + 30 mV. The sodium-potassium pump starts to operate once the action potential is completed. As a result, the axon membrane will obtain a resting potential by repolarization.
Now the process takes place in reverse order. It is a reversal of the process that has taken place during an action potential. Here, potassium ions will be rushed inside and sodium ions will be rushed outside. Impulse would not be transmitted through the nerve fibre during the refractory period.
In the case of white fibres, saltatory propagation takes place. That is impulse jumps from node to node and it increases with increase in the speed of nerve impulse. It is around twenty times faster compared to that of the non-medullated nerve fibres. The transmission of nerve impulse would rely upon the diameter of the fibre. For instance, the nerve impulse of a mammal is one twenty meters per second whereas nerve impulse of a Frog is 30 meters per second.

[@amalidrees5233]

Excellent way of teaching sir ! Pehli dafa samj aaya hy action potential

[@romeokhan-vw3st]

Easy way to deliver lecture on such difficult topic ❤❤❤

[@satishprasad8413]

LOVE U SIR FROM NEPAL,U Make this Difficult topic into Simple By ur Beautyful explanation.May God Gives U success on ur youtube channel. Tqsm sir

[@jenniferjasmineo5787]

Just curious....how can u understand urdu if u are from Nepal??

[@scarlet3328]

ap boht easy words m boht acha smjhaty hain.. thank you so much

[@achaudhary6901]

You're so amazing sir...You made the concept completely understandable ✨

[@vaishalibhambani3545]

What an amazing explanation to a difficult to understand topic! Thanks alot Sir 🙏

[@powerofknowledgeacademy]

thanks and welcome

[@Einstein-mc]

​@@powerofknowledgeacademy huma toh kabhi reply nai kiya sir jee ap na

[@mahparariaz4965]

Wonderful sir may you succeed more and more in this world and the world hereafter

[@mahnoormunir1845]

Finally I understand this concept.

[@ZaraAsra456]

JazakAllah khair Sir for your help

[@misbahhameed3515]

Thank you soo much sir itna difficult topic itny jaldi ho gia

[@muhammadabubakar5547]

Sir ap ne k+ outside and inside lkhne main ghlaty ke hain❤([k+] in resting membrane) sir ap ne bola shi per lkhane main shaed ghalty ho gye..good luck sir

[@muhammadabdullah9367]

Amazing way of teaching thank you sir

[@pharmacywidmuskan]

But sir board pr 1 thing wrong h..... More potassium outside rhta h and leas potassium inside rhta h resting membrane potential me

[@lizzaalianaa8648]

@@thestranger2905 Array, she *@Muskan Gupta* wants to say that Sir is completely right about the topic and concept but has not Correctly written on the BOARD.... I too noticed it, as Sir has written "More K+ Outside in case of Resting potential Membrane which is actually wrong"..... Padhaty Padhaty to Sir sahi bol rhy h bus likhnay mai hi correction ki zaroorat h....

[@thestranger2905]

@@lizzaalianaa8648 okay thanks 👍

[@aylis3675]

Yes there is written mistake on board

[@adventureslife5628]

No more sodium ions outside while more pottasium ions inside

[@manaspandey446]

sb cheej sahi , lagta hai tum logo ne jyada padh liya hai tabhi tum logho ka deemag ghoom gya hai

[@b-151nazia6]

For the very first time i got this lecture ....Allah apko kamayab kry sir g ❤❤❤❤❤❤❤❤

[@jennythar2429]

Sir your videos is so nice all

[@nazishkhan870]

Sir u made this easy to understand...

[@yaserkhan4878]

Sir you are really amazing 👍😍👍😱👍👍👍👍👍😍

[@b-151nazia6]

In RMP, Membrane gets negitively charged due to K influx and Na outflux but keep in mind thst there are many inorganic compounds in the neuron with negetive ions eg amino acids,many proteins ,RNA and DNA which also makes inside of neuron more negetive 🔥🔥🔥🔥🔥🔥🔥🔥

[@Chotimotimistakes102]

Sir ny k+ ko bi more outside likh dia..confuse hony lgi thi

[@sadiabatool8863]

Thank u so much sir outstanding exp

[@sumanbhunia4836]

Thank You Sir, Radhe Radhe Radhe-Shyam, 🙏।

[@adrishalijutt1263]

Sir kindly screen shot k liaa bhi allow kia krain

[@pravitmangal1910]

Good explanation in short time keep it up

[@Mhkydv20]

Sir mai aapki bhit vid dekhti hu bhit acha explain krte ho

[@joyapandit7317]

Ye complete process hi nerve conduction Hai kya??

[@Afnan_jat]

Thanks a lot ♥️♥️

[@jassisingh7977]

Very good explanation of difficult topic

[@meertahir8736]

Thanks sir. God bless you

[@barkhurdarkhan5781]

Sir very nice lecture

[@pharmacywidmuskan]

Very nice... Explanation

[@MuskanKhan-gk7qm]

Best explained videoooo sir❤️❤️❤️❤️

[@zahru8992]

Thnkx Alot! Amazin’

[@KhanKhano-jt3gx]

Sir outside potassium kam hain ap ne more potassium leeksa hainn😊😊

[@jehanzaibsohail710]

Everything is complete in lecture but sir one thing is missing in the lecture anions? Which is more inside the cell then k 😊

[@murtazamalik8483]

Very nice explanation

[@sanaashfaq3012]

Thanks Sir ❤️❤️❤️❤️

[@abubakarikram7538]

Sir you have some mistaken on white board more Na outside less Na inside more k outside less k inside ? ????

[@b-151nazia6]

Everything is ok bs K inside se more he or outside less he sir g ne likhty hoy ghlti ki he bolny me fir bhi sai bola

[@HiraJunani]

Thanks 😊

[@salmanabbasi5431]

Sorry yeh samjh mai. Nh aaya
K+ repolarization k baad bahir ziyada hota hai aur Na+ andar ziyada hota hai toh active transport kiyon ho rhi h
Potassium ko bahir se andar aane main aur Na ko andar se bahir jaane main ATP use kiyon ho rhe hen
Waiting for your kind response

[@nahk235]

Sir aap ne support and locomotion waly chap ky lectures kiun nhi daly?

[@andysingh9746]

Thank You sir So much 😊

[@kaushikmishra892]

❤️❤️❤️❤️ so nice explain

[@arsalanadil9983]

amazing sir very nice lecture

[@SaraUmar-t2n]

Thanks sir 👍

[@meenhalalikhaskheli3627]

Sir sa ma( plasma membrane of neuron) maintains a change of -65mv ( variable between -40mv to -90mv)

[@rahmanuddin8216]

Nice lecture

[@fall11vy]

thank you sir

[@fawadsherazi3757]

Outstanding sir 🎉

[@sadamhussain251]

Mashallah sir attractive lec ❤

[@Sunsetlife367]

thank u so much sir

[@broken8816]

Thnx 👍 sir

[@muhammadzaid1876]

Sir really u r amazing ❤

[@asifaliabbasi6855]

❤❤❤ amazing sir

[@afshanarshad9337]

What is electrical pulses?

[@Sajal07]

Thanks a lot sir ❤️

[@ayeshaashar6061]

Sir depolarixation k wkt Na/K pump kam kr rhe hote hai?

[@b-151nazia6]

Same question

[@jannatkhattak7273]

K pher thou positive charge hai thou and had kaisey negative charge aghye plz some one answer me plz

[@ihtishamhussain9292]

Sir you have write ,less k* inside instead of more.

[@swatimaliyan8925]

So amazing 😍😍

[@misbahhameed3515]

Sir ap na bola sae hai likn board per ghlata likha hua potassium outside Kam hain aur inside zayada hain

[@AhmedMujtaba-qq3mi]

Thanks Sir❤❤❤❤

[@binsamadcattles1255]

Short time More explaination🔥❣️

[@uzairbro7777]

Great

[@wajeehulislam1991]

Tnx sir keep hard work

[@mahnoornoor4201]

Really helpfulllll

[@iftikharahamd9786]

very nice sir

[@user-kx8rj8me7m]

Masha allah
🎉🎉🎉🎉

[@asifmir4005]

shukriya bsir ❤️uh

[@litubhai2106]

Sir repolarization and polarization Na nad K ion ki concentration ke bare me thoda check kijiye....

[@sakindarkumar9128]

Navile concline

[@cadetummefarwa6612]

Sir iska swal kesy ata h fed brd mn?

[@user-dh2bt3iu6s]

Amizing

[@QuickQuiz-900]

Please note the mistakes sir . 3:31 second

[@mashrafarain4417]

But sir hmari book m (rmp)_65 h or depolarization +40 h

[@Ankitjjireh]

More Na+ inside hoga
Confusion hai

[@generalinformationin3253]

Hlw sirr....r u from pakistan??

[@nazigul9662]

Oho bi what apko Indian lag raja ha in his Name is Abdurehman

[@generalinformationin3253]

@@nazigul9662 ha i am indian aaur mera naam saalim sayyed hai....also love pakistan❤❤😊😊

[@kavitabind1131]

Very nice 👍 class

[@shamaabbasi5589]

Sir ap bata kch r rhy hen r likha hoa kch r hy shi kia hy??

[@mishikj989]

U wrote more k positive outside that’s not right ....instead of more K pos inside and less k pos inside ... and in repolarisation thori confusion hai ..can u please make video again??

[@HAROONYASIR12]

actually ,more k positive are on outside when the action potential membrane passes then the voltage gates open thats how its more on positive side in repolarization state and Na is more inside and when the hyperpolarization state achieved then it goes back to normal in few miliseconds

[@malikimranahmad4516]

Dear sir...end me ap kuch mistake kr gy hy...kindly review your lecture

[@user-nr8mg4pc9u]

Kis chez mei kindly tell...

[@kingrajpoot5720]

More k+ inside and less out side ......

[@Ana-xo7if]

Outstanding 💜🙏

[@Malang-i8z]

Itny adds hai lecture tu itna hai hi nhi

[@AtifKhanii-fv1fv]

🎉🎉🎉🎉🎉

[@syedarnan2867]

Walaikumsalam❤

[@bakut940]

Thnku sir 😊😊

[@motivationspeaker2654]

Walikomassalam

[@TechnicalHubpk.]

Ok

[@afzuUkhann79]

❤❤❤

[@afzuUkhann79]

❤❤❤❤❤

[@skhan12132]

👌👌👌👍🏼♥️

[@user-cr4kd4cd8t]

Jay Shree Ram

[@ZaidLife]

♥♥

[@ABDULRASHEED-ck7hn]

Teachers are losers 😂

[@sarfarazbaloch783]

Thanks sir

[@aliRaza-wc7mq]

Thanks sir ❤❤❤

[@uzairbro7777]

Thanks alot sir