TWiV 1149: Mary Estes, A Gutsy Virologist
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- Опубликовано: 18 сен 2024
- From the annual meeting of the American Society for Virology, Kathy and Brianne speak with Mary Estes about her career and the research of her laboratory on viruses that infect the gastrointestinal tract, including rotavirus and norovirus.
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excellent job, loved kathy and brianne co-hosting, mary was off the charts!!
Excellent guys. Very beautiful. Thank you very much
LOVED the easter egg at the end.
You guys are beautifully colour-co-ordinated.
Thank you very much for this presentation. Important for those who have young children, too.
I really enjoyed this one. Thank you to ASV, fascinating - and I'm not even in the field.
Same here! During the early spring when the TWiV folks were talking about getting ready for ASV I kept thinking, "I wonder if they need volunteers?" 🙂
Excellent guest! NGL tho - I busted a gut at the end when Jenkees' Disorganized Fun played😂😭☠️ Classic early YT content
Excellent interview. Very enjoyable!
Interesting! Thanks ladies for your science work
Thank you for this.
I hope you have more all-female twivs! However hard they may try, the men do dominate too much. With all-women, the turn taking in conversation is bound to be better.
Have there been any recent episodes on Covid? Looking for in depth explanation of the efficacy of the current vaccine.
@@Steve-Richter Yes! The weekly clinical updates often include the news on covid, new treatments, etc.
Genuine question.
When I was at school, I remember being told that "viruses" are not alive, and are little more than "genetic information". I remember thinking that this seemed a little strange, since I could picture a bacterium, through being alive, "attacking" or "invading" a cell (I have since come to understand that bacteria are benign, at worst). I didn't think much more about this for years.
However, since coming round to the idea, like many others have, that "viruses" are entirely imaginary (after the Emperor's New Coronavirus charade) I am now very interested to know how "virologists" can possibly explain "virus behaviour"; how "viruses" could do things such as "bind to a cell", "insert genetic information", "replicate", "mutate" etc. etc. How could genetic information "do" anything, other than float about, and eventually get broken down by bacteria or otherwise passively processed?
There are numerous issues with "virology" (it largely creates questions for itself through its extremely "complex" and equally meaningless mythology), but that's one which I clocked about twenty years ago at school. Those in the video seem to take "virus" agency wholly for granted, but building on presupposition and falling back on "authority" is not scientific (and as someone not "trained in virology", it's sort of embarrassing to have to raise questions as elementary as this). It baffles me that a "virologist" wouldn't stop and consider such a simple aspect of the issue.
Any takers?
Because viruses, though not meeting the scientific definition of life (As particles), are NOT just genetic information. Like cells, viruses rely upon and use the ribosome to create functional proteins that grant them certain functions, and many of the functions you describe here: Attachment, Entry, Genome replication, Assembly, and Release (You already have most of the basic steps of the infection cycle down!) function off the back of proteins and sometimes lipids that allow for this.
Though viruses don't have their own ribosomes, and of course are dependent on cells for this, making them obligate parasites.
You seem to be getting caught up on semantics when you'd benefit a lot from actually learning more about virology for yourself. It would answer a lot of your questions about the functionality and identity of viruses, and I think it's hasty to call it a problematic, unscientific field, when you haven't actually personally looked at the science.
On this very same channel there's a playlist: "Virology Lectures 2024"
They also discuss many of these functions in this very same podcast episode, just gotta pay attention ^_^
Hope this helps :)
If your only answer to "Why haven't these experts thought about X" or "Why aren't leaders doing anything about Y" is "Because they're stupid" or "because they're lazy," then it's *you* who doesn't understand the thing you're expecting someone else to solve.
Anytime you feel yourself saying "because they're stupid," use that as your own signal for you to learn more.
It is hubris to assume that the people who have dedicated their entire lives to research, spending grueling years and years in school, often having to move several times, writing and defending a thesis to earn a PhD, DSc, DrPH, going into huge amounts of debt to pay for their education, and scraping by on a university professor salary, writing grant after grant after grant to get your lab funded... you get the picture. This is not a line of work/study for people who can't be bothered to think about the things you're suggesting they're not thinking about.
I think Randy’s brain got dipped into Clorox
This is the dumbest thing I’ve seen
You don’t like high quality expertise from actual experts ?
It's fascinating how dumb the "virus" mythology has become. I wouldn't even know where to start with how farcical this paradigm is. Never has it been easier for the intuitive layman to establish the truth over the "expert" than in "virology". I lost count of the number of falsehoods within the first couple of minutes of the opening speaker. I love it!
Nobody cares. If you dont like it, get out.
@@Renatus_Eruditus Apparently you care enough to tell me to "get out". This can only mean that you care. And it is telling. Honestly, do you take it all at face value? Do you not have any questions over the assertions of "virology"? Any curiosity about alternative hypotheses? The answers of course are yes, no, no. And that's weird. Understand that it is weird. I'm continually curious about propositions contrary to my understanding.
I've looked at far more material aiming to reinforce the paradigm than undermine it, and it is "virology's" own terms which undermine it. If you look clearly and honestly at it, and think about what you are seeing, it quickly and easily debunks itself. It has far more to do with intuition and honesty than intelligence. Experts, very often in life, and always with "virology", aren't. Perhaps it's more accurate, or more charitable, to say that their expertise is meaningless.
Following the ever-more-intricate mythology (currently the obviously-comical "meta-genomic sequencing") is fascinating, and funny, in itself, but just as fascinating are the psychologies and archetypes of its proponents (see your response).
I follow this stuff because it is interesting. Not on its own terms, of course, but objectively, as you would watch a person's descent into madness.
@@John-he6yh What are some of the falsehoods you think exist, and on what basis do you think they're false?
I believe the "Intuitive layman establishing the truth over the expert" concept you're referring to is in actuality a severe case of Dunning Kruger. You went from your previous question to this, which is just mean.