I am so glad to have found your channel just now! I’ve got quite a bit of catching up to do. I suppose that means I get to binge watch all your videos today! (At least until my brain gets full…)
Once again, thanxs for the excellent update. Dr G, you have used the famous last line of Gatsby before but it's relevant so ok. Some strange comments here again best ignored🤪
If anyone wants Novavax be sure to get it before the end of Oct or Nov. The new batches being shipped out and distributed will be expiring quickly unless the FDA extends their expiration date.
Doctors, I have a layman's question: 1. It seems like a vaccine that provided a vast reduction in Mpox lesions would be better than nothing at all, but, is there then the risk that the virus mutates and becomes more vaccine-resistant?
Viruses mutate 1000s of times in each infected cell. Mutations that lead to greater transmission allow evolution to gain more hosts. This occurs regardless of vaccination. Only vaccination (or infection--if survivable & may cause lasting damage depending on the pathogen) can protect you from serious illness. The % of the population getting vaccinated makes a huge difference depending on the virus.
Manhasset Bay! I used to spend my summers swimming in that bay - totally poluted (junk from boaters and marinas, but most probably from industry) back in the 50's. Expected to die from some weird toxins, but I'm still healthy and disease free at 77.
It's great that things like the expansion of telehealth means there is some preparation for the next pandemic, but I wish there were more resources put into PREVENTION of the next pandemic. I hope that Kamala appoints a pandemic czar, who will liaise with bodies like the CDC and WHO etc.
I wonder what you guys talk about when you're on a line to get chem* and recognize that your fellow podcast viewers are on the same line! I do tell my patients to compare and contrast what You guys and Ladapo say.
I don’t send any body to Ludapo. Why would u purposefully mislead my patient ? That’s extremely unethical. Don’t you know enough science to know that Ludapo is lying ?
Curious if n the mix of az vs j in the paper comparing them with novavax and moderna. Worth noting az didn’t pre fusion stabilize the spike and jj was done as a single shot. So these differences may be involved in the different results seen.
Classicly smallpox vaccine had risk and was administered on a five year schedule. Vastly safer than smallpox. There may be first, second, third refresh ... safety data. It may be valuable think about using multiple types of vaccine in a sequence. The comparison of vaccine types included J&J so this was early and now J&J is history. Today one might explore titrated doses to find an equivalence dose per product. Also measure reaction induced discomfort.
I've watched you all for years and still don't know if I can trust you. I only watch to learn the textbook knowledge. So I can flash the knowledge with people who think, like yourselves. Not people who think differently. And for that I do thank Vincent and Daniel.
What is not to trust? Offering information based on the science they have …which as they collect more data from more research overtime…they update that information. Much of TWIV is a discussion about that information. You listen and take a deeper look if you like.
I do appreciate the science but please, Mr. Griffin, speak up. At the beginning of your sentences you tend to be super loud, when there is no or hardly any information conveyed yet, but when it comes to the end of a sentence, when the real information/number/advice is finally spoken, your voice is so quiet, only dogs can ever hear it. It would be really nice if that could be improved.
Maybe at patients with cold agglutinine must avoid to decrease blood capillary temperature at lung level ? Did we know at what patients,,cold agglutinine,,did occur ?
what a load of bull. The vaccinated DO NOT SHED for a couple of months. While some spike is preserved in the germinal centers for the use of somatic hypermutation and affinity maturation. The rest is degraded quite fast. mRNA quickly degrades and only lasts a couple of days at most (in human cells I've seen 600 minutes/10 hrs half life). And there's no replication of this mRNA in the cells. Learn some science.
I’m still hearing denial and conspiracy theories in the clinics where I work. It’s disappointing (but not surprising) to hear it from the nurses, but very disheartening to hear it from the MDs. We are all trained to follow the evidence. 🫤
The proof that doctors / nurses trained to follow science can be so easily swayed is, to me, one of the worst aspects of the pandemic. They're human and are afraid. Urgent care is so poor now as to be essentially useless. Our system needs so much work!
If you need to seek so damned hard to find something true in the information our experts and politicians gave during covid-19... It is not easy to believe in medical institutions. But the ones who didn't see that won't never see it. Accept it as they may believe what they want. But don't speak that science is practiced. Science likes to be falsified. If your colleagues can't have another opinion than yours. Then you yourself don't like the scientific approach.
I strongly follow the opinion of the Florida Department of Health and also advise to NOT take mRNA against SARS-COV-2. Updated guidelines from 12 september.
@@StefaanNijs Many people can't tell the difference between a troll comment or a sincere one, especially when it comes to comments on a virology channel. If your joke comment directs someone to a source of dangerous misinformation, you've done more net harm than good. Is a joke that important? There are a zillion less harmful ways of making someone laugh. I realize you can't protect everyone, but every pandemic starts with a single infection.
I really respect the dedication ur team has to share knowledge. love from Malaysia
I am so glad to have found your channel just now! I’ve got quite a bit of catching up to do. I suppose that means I get to binge watch all your videos today! (At least until my brain gets full…)
"Brain microbiome" is the most thought-provoking concept I've heard in a minute.
TWiM 58 team discussed brain microbiome. I was taught the brain did not have a microbiome but that was years ago in undergrad. The topic intrigues me.
@@LisaMartinez-ri6ve Tomorrow I will track down TWIM 58, thanks for the pointer!
You are welcome . It is audio only by the way.
Covid discussion starts around 19:45
Thanks.
Thanks!!!!
thank you both...great info...!thank you!
Once again, thanxs for the excellent update. Dr G, you have used the famous last line of Gatsby before but it's relevant so ok. Some strange comments here again best ignored🤪
Thanks Dr G and Dr R!
That is excellent. Thank you very much
Thank you.
If anyone wants Novavax be sure to get it before the end of Oct or Nov. The new batches being shipped out and distributed will be expiring quickly unless the FDA extends their expiration date.
@@Rabbitt-d6y it’s already out. Pharmacies etc are just waiting for the supply to arrive.
Doctors, I have a layman's question:
1. It seems like a vaccine that provided a vast reduction in Mpox lesions would be better than nothing at all, but, is there then the risk that the virus mutates and becomes more vaccine-resistant?
Viruses mutate 1000s of times in each infected cell.
Mutations that lead to greater transmission allow evolution to gain more hosts. This occurs regardless of vaccination.
Only vaccination (or infection--if survivable & may cause lasting damage depending on the pathogen) can protect you from serious illness.
The % of the population getting vaccinated makes a huge difference depending on the virus.
Manhasset Bay! I used to spend my summers swimming in that bay - totally poluted (junk from boaters and marinas, but most probably from industry) back in the 50's. Expected to die from some weird toxins, but I'm still healthy and disease free at 77.
It has been a while (6 months possibly) since I've seen Dr. Griffin. What has he done to accomplish such dramatic weight loss?
It's great that things like the expansion of telehealth means there is some preparation for the next pandemic, but I wish there were more resources put into PREVENTION of the next pandemic. I hope that Kamala appoints a pandemic czar, who will liaise with bodies like the CDC and WHO etc.
I wonder what you guys talk about when you're on a line to get chem* and recognize that your fellow podcast viewers are on the same line! I do tell my patients to compare and contrast what You guys and Ladapo say.
I don’t send any body to Ludapo. Why would u purposefully mislead my patient ? That’s extremely unethical.
Don’t you know enough science to know that Ludapo is lying ?
Curious if n the mix of az vs j in the paper comparing them with novavax and moderna. Worth noting az didn’t pre fusion stabilize the spike and jj was done as a single shot. So these differences may be involved in the different results seen.
Classicly smallpox vaccine had risk and was administered on a five year schedule.
Vastly safer than smallpox. There may be first, second, third refresh ... safety data.
It may be valuable think about using multiple types of vaccine in a sequence.
The comparison of vaccine types included J&J so this was early and now J&J is history. Today one might explore titrated doses to find an equivalence dose per product. Also measure reaction induced discomfort.
I've watched you all for years and still don't know if I can trust you. I only watch to learn the textbook knowledge. So I can flash the knowledge with people who think, like yourselves. Not people who think differently. And for that I do thank Vincent and Daniel.
What is not to trust? Offering information based on the science they have …which as they collect more data from more research overtime…they update that information. Much of TWIV is a discussion about that information. You listen and take a deeper look if you like.
But, Daniel has a bow tie.
If you want textbook knowledge, check out Dr. Racaniello's series of virology lectures. Great stuff!
I’m grateful to Daniel and Vincent. It’s because of them that I asked for Paxlovid immediately after I tested positive last year.
I do appreciate the science but please, Mr. Griffin, speak up. At the beginning of your sentences you tend to be super loud, when there is no or hardly any information conveyed yet, but when it comes to the end of a sentence, when the real information/number/advice is finally spoken, your voice is so quiet, only dogs can ever hear it. It would be really nice if that could be improved.
Maybe at patients with cold agglutinine must avoid to decrease blood capillary temperature at lung level ?
Did we know at what patients,,cold agglutinine,,did occur ?
Maybe at some Covid19 patients,,happy hypoxia,, was induced by,,cold agglutinine,, or by high cryoglobuline IgM level ?
1word=homogeneity, mammals? :)
The vaxed shed for a Couple of Months
We are all full of the spike;
!The purebloods Not out of the Woods!` !
Load balancing... nonvaxxer 420
what a load of bull. The vaccinated DO NOT SHED for a couple of months. While some spike is preserved in the germinal centers for the use of somatic hypermutation and affinity maturation. The rest is degraded quite fast. mRNA quickly degrades and only lasts a couple of days at most (in human cells I've seen 600 minutes/10 hrs half life). And there's no replication of this mRNA in the cells. Learn some science.
Raccoon dog. Every time I hear that I cringe.
The bowtie opening is getting stale
I like it.
@@immortaltyger1569 ditto your comment. I like it too😎
In the time/effort it took you to type your comment you could have moved the video slider past the part where the virologists hurt you with their joy.
Go somewhere else
I’m still hearing denial and conspiracy theories in the clinics where I work. It’s disappointing (but not surprising) to hear it from the nurses, but very disheartening to hear it from the MDs. We are all trained to follow the evidence. 🫤
The conspiracy theories have all come true! 😂
The proof that doctors / nurses trained to follow science can be so easily swayed is, to me, one of the worst aspects of the pandemic. They're human and are afraid. Urgent care is so poor now as to be essentially useless. Our system needs so much work!
If you need to seek so damned hard to find something true in the information our experts and politicians gave during covid-19... It is not easy to believe in medical institutions.
But the ones who didn't see that won't never see it. Accept it as they may believe what they want. But don't speak that science is practiced. Science likes to be falsified. If your colleagues can't have another opinion than yours. Then you yourself don't like the scientific approach.
Yes, quite shocking to hear misinformation from medical staff. I can’t believe the ignorance coming from physicians
Why are nurses more likely than doctors to believe conspiracy theories in regard to conclusions they draw from the evidence?
I strongly follow the opinion of the Florida Department of Health and also advise to NOT take mRNA against SARS-COV-2. Updated guidelines from 12 september.
😂
You lost everyone at Floridah.
😂😂😂 OMG You are obviously listening only to troll.
Trolls troll. Lough with others. I am happy with your attention. It means I am in the right direction if I get trolled. 😀
@@StefaanNijs Many people can't tell the difference between a troll comment or a sincere one, especially when it comes to comments on a virology channel. If your joke comment directs someone to a source of dangerous misinformation, you've done more net harm than good. Is a joke that important? There are a zillion less harmful ways of making someone laugh. I realize you can't protect everyone, but every pandemic starts with a single infection.