Identifying patients with alpha1-antitrypsin deficiency | Alpha-1 symptoms and diagnosis

Watch this video to learn why genetic screening for alpha-1 in all patients with COPD is recommended, regardless of age, smoking history, or FEV1.[1-5] It’s difficult to detect alpha-1 without genetic testing because its symptoms are similar to COPD and asthma.[1,2,6] A patient with alpha-1 cannot be identified by symptoms or medical examination alone. Genetic testing is required to diagnose alpha-1.[7] You can learn more at bit.ly/3zWFkP7
More information about alpha-1: bit.ly/3ndOTFR
Alpha-1 screening guidelines: bit.ly/3BRB4B6
Order free AlphaID™ screening kits: bit.ly/38OVQVH
References:
[1] World Health Organization. α1-antitrypsin deficiency: memorandum from a WHO meeting. Bull World Health Organ. 1997;75(5):397-415.
[2] American Thoracic Society/European Respiratory Society. American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med. 2003;168(7):818-900.
[3] Willie KM, Sharma NS. About alpha-1 antitrypsin deficiency. CHEST Foundation website. foundation.che.... Accessed July 12, 2021.
[4] Sandhaus RA, Turino G, Brantly ML, et al. The diagnosis and management of alpha-1 antitrypsin deficiency in the adult. Chronic Obstr Pulm Dis. 2016;3(3):668-682.
[5] Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2021 Report.
[6] Campos MA, Wanner A, Zhang G, Sandhaus RA. Trends in the diagnosis of symptomatic patients with α1-antitrypsin deficiency between 1968 and 2003. Chest. 2005;128(3):1179-1186.
[7] Lung disease. Alpha-1 Foundation website. www.alpha1.org.... Accessed July 12, 2021.