How to test for Celiac disease (Coeliac Disease) | IgA TtG and Biopsy explained
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- Опубликовано: 24 авг 2024
- Doctor O'Donovan explains how patients in the UK are tested for Coeliac Disease. Coeliac disease is a condition where your immune system attacks your own tissues when you eat gluten - a dietary protein found in 3 types of cereal:
* wheat
* barley
* rye
This damages your gut (small intestine) so you are unable to take in nutrients. Coeliac disease can cause a range of symptoms, including diarrhoea, abdominal pain and bloating.
Currently in the UK testing for coeliac disease involves two things.
* a blood test to help identify people who may have coeliac disease
* a biopsy of part of the bowel (known as the small intestine), to confirm the diagnosis
While being tested for coeliac disease, you SHOULD eat foods containing gluten to ensure the tests are accurate. This means eating gluten in more than one meal a day, for a minimum of 6 weeks, before testing is performed.
For more information see: www.nhs.uk/con...
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My son was diagnosed at 7 months old that was 1983 and i have developed it and was diagnosed 2017 i am glad i had the education bring up my son on a gluten free diet so i knew what to do for my self you have to get in to the habit of reading labels and cooking as much as you can so you know its gluten free.
I wish doctors tested people for CD early in life. In the US, they seldom test for it, as if they don't know anything about it. It's really a disgrace.
Thanks for the comment
I agree!!! I’ve lived a life of he double L since I was a child. Just got my blood test today and can’t wait for my results.
In italy every child is tested for coeliac disease at 12months of age
How's your test results?@@arianatorres424
You can test yourself.
I am Coeliac with Dermatitis Herpetiformis. I was diagnosed from a biopsy from a DH lesion. It took many years to reach that point. The link between CD and DH was only discovered many years later. Over the first two years on a gluten free diet my weight when from 50 kgs to 85 kgs. Then my Dr said I had to lose weight. Seriously? I am now 72kg and 76 years and keep very well.
I am 56 and literally just been diagnosed, after years of suffering, hopefully i have suffering so no one else has to go through what i have went through, my dr has the endoscopy results and his secretary told me no further treatment needed, i have a lot of health issues and thankfully the hospital gave me my diagnosis in black and white , i had to do a little research for the big medical words and now i have ve done that , i can stop being paranoid and second guessing myself and take my dr through the proper procedure for treating me how they have, thank you Universe for all .
Keep lifted .
Here in Australia it is possible to have a gene test for Coeliac disease (not covered by Medicare rebate however) if people have been eating GF for a while and are unwilling to do a 6 week gluten challenge before blood test or Endoscopy.
That is a good idea. Why go through a lot of suffering to get back to where you presently are and that is on the diet.
I don’t get bloated or diarrhea. However, I have extreme chronic fatigue and brain fog. I live in the poverty range and use the food bank. Therefore there’s no way I can eat gluten-free. $10 for a loaf of bread and the slices are the size of the palm of my hand, plus every condiment under the sun is full of wheat. How are you supposed to eat gluten free when you have less than $100 a month for groceries?
Hi! Eat rice, potatoes and vegetables and moong dal for protein. Add a drizzle of olive oil. Avoid anything ultra processed. I eat so many carrots and potatoes because of this problem. I sprinkle sea salt and olive oil for flavour.
Try carnivore diet like lion diet with fatty meat and organ meat like liver, butter, etc. Minimum 3-8weeks.
@@hollywood1426 You can only eat that for so long!
There are many foods that don’t contain gluten etc
I've been suffering for months with something like this. I'm too terrified of needles and suffer with social anxiety. 😞 Feels like I'm stuck in a vicious loop.
@@noglu106 I have all the symptoms but I just can't bring myself to see a GP. For me the whole experience is terrifying.
I avoid dairy and gluten products which costs a small fortune. My symptoms have eased off a little bit since doing so but I still a have discomfort with most meals.
I've put off contacting a GP because off my phobia and anxiety but now it looks like I have no choice.
You must get your self to a doctor if it helps ask a friend to go with you.
@@lesleywhibley Eventually I did. 👍 Much better now.
@@SL1PSTAR
What happened ?
How do doctors distinguish IBS/SIBO apart from coeliac diseases practically?
Logically, would it not make sense to use the GF diet to see if anything changes. If symptoms don't improve, chances are it is not coeliac?
It is one of few conditions in which the patient can actually test (with the strict GF diet) and effectively treat themselves. When the medical profession finally uses the diet as a test is when more people will be diagnosed in a timely manner. This is what happens when a country with national health care assumes everyone has insurance. What would you suggest to someone who cannot afford the test. Suffer the symptoms until you can get "officially diagnosed"? I think not.
''eat gluten for 6 weeks'' insanity
Shoutout to my fellow undiagnosed sufferers in the comments who have doctors refusing to do the biopsy because "you can just avoid eating gluten" or some other BS.
"Why do you want to know if you have Celiac?"
"Either you have it or a gluten intolerance, and the treatment is the same: just don't eat it."
"The blood test was negative so I see no reason to pursue a biopsy."...."It doesn't matter if you haven't had it in years-"
Excuse me while I flip tables. 🙃
Those doctors who suggest just avoiding it make the most sense of all. You have symptoms that could be undiagnosed Celiac and trying the diet first to see if anything changes is logical.
I apologize in advance. This response went off the rails and I was seemingly feeling some kind of way, which wasn't my original intent. It's also not directed at you. I'm salty at the doctors who ran me in circles for 15 years while I declined to the point of disability.
TL;DR medical terminology present in a patients record (or lack there of) impacts not only the outcome of care for the patient, but also how much is billed to them.
Avoiding the trigger for symptom management is logical. That's not my problem - I haven't purposely had gluten in well over a decade.
The issue is, I want to have the diagnosis in my chart due to the co-morbidities that come with having an autoimmune condition such as Celiac. The terminology on a patients chart upon initial exam is every doctors first impression. If it says "Celiac" there instead of "gluten intolerance" when a doctor is considering symptoms of x, y, or z, it can be a game changer.
Unfortunately we live in a world of mind games and gaslighting with healthcare professionals. There are few things as upsetting as being sick for so long, and yet, the doctor tells you there's nothing wrong. The major red flags on your lab tests weren't set off. Yet.
Additionally, in the US it's expensive to be sick. The management of a chronic illness is billed to insurance in a different way than other visits - it varies by plan, but most in the US cover chronic conditions by law. That's assuming one HAS insurance.
It's also very strange to me how reluctant doctors are to just..do the testing. There was no reluctance to throw me at a Rheumatologist, ENT, Radiologist, or even a Neurologist for various things. I've lost count of all the in office procedures performed on me, plus a surgery, and yet...no the celiac test is too much.
AHH so sorry for my ranting
What about pins and needles/ numbness? Could this be related ..
b12 deficiency?
Yes, it is related! Celiac disease can cause neuropathy, and also damage a part of the brain … the cerebellum. When this happens your gait will change and you’ll have a problem walking. It can also cause arthritis. Most people and even some doctors think it targets just the digestive system.
Does this disease lead to alopecia areata?
My celiac was negative for bloods but the IGA is low apparently which this does not help how much gluten is actually still in - Ive had it for 5 years now id say and on gluten free diet......I am use to it but they did not get it until after two biopsies I lost more and more weight and continued with issues for my gut and after being wrongly diagnosed with "IBS' and then possible crohns and then go to celiac now
my IGA is at 0.68 though so ye low and my vit d is at 20 (Very low)
can you speak english?
diagnosed with gluten intolerance... what is the difference between that and CD ?
Please see this resource: www.nm.org/healthbeat/healthy-tips/celiac-disease-vs-gluten-intolerance-infographic#:~:text=%E2%80%9CCeliac%20disease%20is%20an%20autoimmune,health%20like%20celiac%20disease%20can.%E2%80%9D
@@noglu106 not entirely, CD requires you to pay much stricter attention to cross-contamination as well as not eating gluten copntaining food. This could be things like cutting gluten-free bread on a cutting board that has also been used for bread with gluten, or frying gluten-free food in a fryer that has also been used to fry food with gluten. All these things can make you feel very poorly as well for most people depending on the severity of the celiac. Although, even if you don't feel noticebily poorly, it still causes internal damage of the villi and cause malabsorbsion of nutrients.
@@rayatateo8094 No it does not. Gluten sensitivity, gluten intolerance and Celiac require the same attention, strict GF diet.
@@wrenfan the point i was trying to make is, CD causes long term irreversible effects, a gluten intolerance causes short term effects that could be severe, but they are reversible and wont damage the body in the long term
@@rayatateo8094 No way, I was diagnosed with CD in 2005 with damaged villi and after going strict GF healed up completely and had absolutely no permanent damage at all. Too much emphasis on diagnosing and too little on the treatment.
Thanks, huge issue.
Thanks
I thought small bowel cannot be visualized via egd ??? How do they biopsy then if you can’t reach it?
I have a endoscopy on Wednesday but I stopped eating gluten for months now they told me to it was causing to much pain is it even worth getting the test at this point if it will make the test inaccurate
I did an EMA test
The results were 64 ru/ml
Does that mean I am sensitive to gluten, or is it celiac disease?
Thank you so much for watching the video and taking time to leave a comment. Unfortunately (and I know this will be frustrating for you), I am unable to give individual medical advice out on this channel. This is because of medico-legal reasons, not knowing your full case, circumstances and it would be unethical of me to do so otherwise. I have included the general resources I used to make this video in the description box but I have to advise that you speak to your own health provider (e.g. doctor, nurse) so that they can properly assess your case. Thanks for understanding.
What if you have negative everything except elevated IgA (388)and high (tTG) IgG (12)
I was diagnosed with celiac from my biopsy, but my blood test are all negative. I don’t feel any better even after eating gluten free for months and I don’t feel any worse after being gluten-free for months and re-introducing gluten. Is it possible I have something that looks like celiac, but isn’t
You either have IgA deficiency and they didn't do an total serum IgA level test, which in Europe is extremely unlikely and then a following IgG test. But if all were negative but you do have small intestinal atrophy than your probably looking at something of other gastrointestinal issue. You have to be 3 months of strict non gluten diet (and I mean strict) before it starts working if that is not the case that's why otherwise go back to your GP you were probably misdiagnosed
With much respect, ideally you wouldn't reintroduce gluten if you was diagnosed with celiac disease. Greetings
@@JuanLopez-vf3mo it’s a real test called a gluten challenge.
@@bigtimeLL thanks for the reply. Have you been diagnosed with the disease? For what i know, even little amount of gluten can damage the body of a celiac person. Greetings
What about HLA DQA1:05? Celiac 2.5?
My GP said he won't test for total IgA, he's only ordered the TTG test for me. Shouldn't be do them both at same time? I'm not sure why he's reluctant to order the total IgA as well. I'm not sure he understands the testing. In the NHS what would it say on blood form? Would it say Total IgA or Total immunoglobulins? If my GP doesn't help me get an accurate test I was thinking of trying a home test kit or going private but not sure if the home test kits are good
The good thing is you still have the upper hand by cutting gluten out. I tested but if I couldn't I would still listen to my body and cut out gluten. I tested for gliadin antibodies because I believe I have gluten induced ataxia. How are you doing?
My DGP IGA was < 1 U/mL. My DGP IGG was 29 U/mL. So I have a low IGA and a high IGG. Does that mean Celiac disease is likely? Does that mean I already have a gluten intolerance? Thank you for anyone with proper knowledge who can clarify.
if i only haven’t eaten gluten for 1-2 days but i have the rest of my life can i still get tested in the next couple days if i go back to normal ?
What if you have been eating gluten free in your diet, will celiac be able to show?
It is important to remain on a normal, gluten-containing diet prior to testing for celiac disease. Do not change to the gluten-free diet before being tested for celiac disease.
@@DoctorODonovan Thank you for your reply. How long do you have to be on the gluten containing diet prior to biopsy?
@@rachelschultz6472 He mentioned 6 weeks in the video :)
Can u tell me My son test report of anti tissue Transgulaminase Iga value is 11.06 and IgG is 1.74 is that normal or positive..
Is it hereditary
It's genetic, but having the gene isn't enough to get celiac disease. A good portion of the population have the genes, but don't have celiac.
What does it mean when the results come back like this
Thank you so much for watching the video and taking time to leave a comment. Unfortunately (and I know this will be frustrating for you), I am unable to give individual medical advice out on this channel. This is because of medico-legal reasons, not knowing your full case, circumstances, and it would be unethical of me to do so otherwise. I have included the general resources I used to make this video in the description box but I have to advise that you speak to your own health provider (e.g. doctor, nurse) so that they can properly assess your case. This is the safest and most ethical advice I can give since this is just intended as a general educational resource. Thanks for understanding.
I wonder why anti tissue transglutimase IgA?
My test was actually IgG. Positive.
Gluten free life is much better ✅
I've tested positive twice through bloods and tomorrow i have the biopsies. Im really really not looking forward to it 😢😢😢
But why cant they just treat you if you're positive through the bloods??? Makes no sense
Treat yourself with GF diet. Why bother with biopsy.
I live in Hungary and my little brother was diagnosed with celiacs 4 years ago. He was only 4 years old so after the blood test the doctors said they don’t need a biopsy to confirm the diagnosis. His IgA level is way less now but it is still not low enough. Is it possible he was misdiagnosed? And if yes what could it be? He never eats gluten, not even the tiniest amount.
Before going gluten free did he have any symptoms that could have been Celiac and after he stopped eating gluten did anything change?
@@wrenfanthe only reason the doctor sent him for a test was that he did not eat any form of meat and they didn't have any other ideas. But none of the typical symptoms like bloating, stomach pain. After two years he started eating some meat, still not the favourite
@@tt_szava I understand. Thanks for the reply.
they should have done a biopsy to diagnose accurately @@tt_szava
I cannot afford to eat, gluten-free!
What do you mean? Naturally gluten free whole food costs exactly the same.
I agree gluten free is more expensive including 😅the protein products. U am also recovering from colrectal cancecoveryer. I need 😊protein there too, in order to continue recovery.
How can i talk to you asap mmmm are you on instagram??
Hi sorry but I can't take individual requests for ethical & medicolegal reasons. I always ask people to speak to their own doctor.