Thanks for watching this episode with Dr. Jason Fung! If you're finding it valuable, please vote by hitting the LIKE button on the video. This lets me know what type of guests to book for upcoming shows. Thanks! -Jesse 💙 P.S. How do you like our new opening animation? :)
Basically I followed his advice on intermittent fasting . Eliminated all processed carbohydrate. Basically eating within six hour window 12 noon and last meal at 6pm. I was on a very low carb high fat protein diet. MY A1C went down from 6.5 to 4.66
@@BillyHannon14 yes I know, but he says the same stuff as the others and his advices are more practical as well. I really don't care what kind of title he has.
When i was diagnosed as diabetic in November i found Dr Fungs videos about fasting. Got my A1C down from 8.2 to 4.8 in 6 months and off all meds. He literally saved my life.
Through Doctor Jason Fung and doctor eric berg I managed to reverse my pre diabetic condition. I used to be 220 lbs but now I'm 170 lbs actually I was extremely close to becoming a life long type 2 diabetic because of my over weight,extremely high sugar diet, sedentary life style. I thank both these doctors they saved my life from an impeding disaster
@@anujbhardwaj3960I was pre diabetic too, and my diagnosis was a surprise and a disappointment for me. I did not experienced any major signs and symptoms that indicated a growing problem. However, if you pay attention to your body and look closely at your skin and other subtle things that we tend to blame on work, age and other things; it may be a metabolic problem. I was 66, and I though that my problems were related to age and extreme levels of stress (this is a risk for developing dm). Here are some things that now I identify as sings and symptoms of pre and full diabetes; dark spots on my calfs and big toe nails, becoming easily tired, bone aches with joints hurting the most, increased urination at least one trip in the night, increased insomnia (always being a light sleeper), skin dryness, cracking heels. I was not overweight and never been, so weight has never been a problem for me. Also emotional distress, anxiety; these were upsetting because I always have had good emotional balance. Everything else was normal per lab results. My only abnormal was my A1C. I hope this helps, but we are all different and you may develop these or other symptoms, also your age may make a difference. I am back to normal, and these symptoms have disappeared. I hope I helped some.
@@annettesanchez4425 high protein food both veg and non veg,fiber,avoiding refined carbs,carbonated drinks and finally exercise along intermittent fasting all of these worked out very well for my in losing 80 lbs of extra weight
Dr Jason Fung is like a saviour. He educates in simple words that people who didn't go to medical school could understand root cause of the issue and take matters of health in their own hands.Much love !!❤
🎯 Key Takeaways for quick navigation: 00:00 🩸 *Insulin and Glucose Dynamics* - Insulin pushes glucose into cells until a limit is reached, causing high blood glucose and leading to type 2 diabetes. 02:20 🍚 *Analogy: Sugar Bowl and Body's Glucose Storage* - The body stores glucose similar to a sugar bowl, but excess causes overflow into the blood, leading to type 2 diabetes. 03:13 🏛️ *Impact of Diabetes on Organs* - Diabetes affects various organs, causing heart problems, strokes, cancers, blindness, nerve damage, kidney damage, and more. 04:25 🔄 *Insulin Resistance and Blood Glucose Regulation* - Insulin resistance occurs when cells resist the effect of insulin, hindering glucose entry into cells and leading to elevated blood glucose. 08:03 📊 *Hyperinsulinemia and Glucose Overflow* - Hyperinsulinemia occurs when the body uses extra insulin to force glucose into cells, resulting in normal glucose levels but high insulin levels. 11:40 🩺 *Identifying Early Signs of Insulin Resistance* - Metabolic syndrome indicators, including high blood pressure, high triglycerides, low HDL, and abdominal obesity, can signal early insulin resistance. 13:34 🛑 *The Misconception of Lowering Blood Glucose* - Lowering blood glucose alone doesn't improve health; focusing on insulin levels is crucial, as seen in studies with near-normal glucose levels worsening diabetes. 16:31 💡 *Onset of Chronic Diseases in Insulin Resistance* - Chronic diseases can begin much earlier in the insulin resistance spectrum, preceding the official diagnosis of type 2 diabetes. 18:33 🧐 *Detecting Diabetic Damage Before Diagnosis* - Protein in the urine can indicate diabetic kidney disease, even before an official diagnosis of diabetes, highlighting the importance of early detection. 20:09 💔 *Insulin's Role in Cardiovascular Diseases* - Elevated insulin levels contribute to atherosclerosis, narrowing arteries, and increasing the risk of heart attacks and strokes. 22:11 🩸 *Insulin and Heart Disease Focus* - Insulin contributes to inflammatory responses and smooth muscle proliferation in arteries. - Cholesterol, while a factor, is not a major one in heart disease compared to smoking and diabetes. - Studies emphasize smoking and diabetes as significantly increasing the risk of heart disease. 24:30 🔄 *Latency Before Type 2 Diabetes* - There's a latency period before type 2 diabetes manifests, during which insulin resistance and elevated insulin contribute to heart disease. - High insulin and inflammation play crucial roles in heart disease, often overshadowed by cholesterol concerns. - Emphasis on the reversibility of diabetes as a risk factor, unlike factors such as age and genetics. 28:25 🚑 *Insulin Resistance and Heart Disease Timing* - The discussion on the timing of heart disease concerning insulin resistance before diabetes diagnosis. - Heart disease can occur before diabetes, and the severity varies based on individual factors. - Diabetes significantly contributes to heart disease, and its reversibility is a key focus. 31:40 🔄 *Accumulation of Fat in the Body* - Insight into the process of de novo lipogenesis and the body's response to excess glucose. - Explanation of how the body accumulates fat in the liver, abdomen, and pancreas, leading to metabolic issues. - Increased abdominal girth and fatty pancreas are indicators of excessive glucose-related problems. 38:22 🍽️ *Treatment Approaches: Controlling Glucose Intake* - The effectiveness of low-carbohydrate diets in managing and even reversing type 2 diabetes. - Recognition of the glycemic index's impact on blood glucose levels. - Dr. David Unwin's success with patients achieving drug-free remission through carbohydrate reduction. 40:41 ⚖️ *Treatment Approaches: Calorie Restriction* - Exploring ultra-low-calorie diets as a strategy, cutting down not just carbs but overall calories. - Highlighting the effectiveness of very low-calorie diets, around 800 calories a day, albeit with potential compliance challenges. - Understanding how reducing all calorie sources, including fats, prompts the body to burn glucose. 42:33 🕰️ *Treatment Approaches: Intermittent Fasting* - Intermittent fasting as a method to allow the body to burn excess glucose during fasting periods. - Comparing intermittent fasting to a strategy of zero calories for specific time intervals. - Stressing the importance of educating individuals on the purpose and benefits of intermittent fasting. 43:43 🍽️ *Methods to Reverse Insulin Resistance* - Three effective treatments: low carb, intermittent fasting, and calorie reduction. - Multiple approaches available, including low carb, cutting calories, and intermittent fasting. 44:40 🌾 *Low Carb Approach* - The significance of low carb in reversing insulin resistance. - Ketosis as an ultra-low carbohydrate diet, its benefits, and measurement. - Flexible approaches to low carb, not strictly requiring ketosis. 47:26 📉 *Calorie Reduction and Nuances* - Dr. Fung introduces calorie reduction as a tool against insulin resistance. - Critique on the conventional calorie reduction approach and its limitations. - Highlighting the importance of understanding the root cause of excessive calories. 58:41 ⏰ *Intermittent Fasting as a Powerful Tool* - Gradual approach to intermittent fasting, starting with cutting out snacks. - Flexibility in fasting duration based on individual needs. - Fasting's impact on burning excess glucose and its role in controlling type 2 diabetes. 01:00:56 🔄 *Fasting vs. Calorie Restriction on Basal Metabolic Rate* - Fasting's impact on basal metabolic rate compared to calorie restriction. - Preservation of metabolic rate during fasting due to increased sympathetic tone. - The advantage of maintaining a higher metabolic rate in weight loss efforts. 01:03:50 💪 *Preserving Muscle Mass during Intermittent Fasting* - Addressing concerns about muscle mass loss during intermittent fasting. - Importance of muscle mass and its preservation during fasting. - Fasting as a method to preserve muscle mass, especially when combined with low carb. 01:04:04 🏋️♂️ *Addressing Muscle Mass Concerns During Fasting* - Fears about muscle loss during fasting are often overblown. - Muscles respond to usage; the concern about losing muscle mass due to fasting is not well-founded. - Measurement methods, such as bioimpedance, can misinterpret changes, leading to unnecessary concerns. 01:08:54 🤔 *Utilizing Strategies for Type 2 Diabetics Without Weight to Lose* - For underweight individuals with type 2 diabetes, weight loss might not be the primary goal. - Low carb and intermittent fasting can be effective tools without necessarily causing significant weight loss. - Low-calorie diets, while theoretically effective, often face practical challenges and are less successful in real-world scenarios. 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Switching to animal based diet (Grass finished beef, organs, raw dairy, fruit, raw honey, cook only in butter/tallow) 6 months in I've lost 40 pounds and have a 6 pack. I also completely cleared my pre-diabetic & autoimmune conditions. And I have diabetes in both sides of my family. Nutrition is #1
@keylanoslokj1806 you speaking for yourself? Lol I have a full head of hair, 2 healthy poops a day, sleep 8 hours every night (I sleep by 11 usually zzz) my skin is glowing and I train hard 6x a week, my muscles have never grown and recovered so fast in my life. Keep trying to cope with your unhealthy lifestyle buddy! Hope you can make a change. Xoxo
@keylanoslokj1806 I'd love to see what kinda diet you live on. to sustain any of what I said involves heavyyyy plant intake. You'd have to eat soooooooo many plants and lentils to reach 200g of protein a day. Compared to me eating a nice steak, or ground beef, few eggs, grass finished whey isolate, yogurt & milk. All natural baby. All bioavailable and nontoxic. How do people who eat out of frozen boxes argue health I'll never understand. 🤡
@keylanoslokj1806 lmao I love it when people don't read and just spew out of anger in the comments, here I'll help you out. What did I say after dairy? What was it I eat? 🤔
Fasting can not only burn off liver fat and make room for insulin to do its job but it can even help restore beta cell function! Some benefits of doing occasional extended fasting: High blood pressure is lowered to normal levels very quickly while fasting. Fibrosis/scarring is reversed over time, including in the heart and lungs. Fasting increases T cell production and regenerates the thymus. T cells are vital in fighting cancer, autoimmune disease and infections but as we age the thymus stops making as many of them. Fasting releases stem cells, which then can become new T cells. Fasting also releases growth hormone, which regenerates the thymus itself, which aids this process! Fasting stimulates phagocytosis, the ingestion of bacteria, plaques and viruses by the immune system. This will also remove any spikes, whether natural or unnatural in origin! Blood clotting is reduced and blood clots and arterial plaque are reabsorbed into the body. Blood sugar and insulin are lowered when fasting, allowing white blood cells to move more freely throughout the body and do their job. Vitamin D plasma levels are increased as fasting improves metabolic health, and vitamin D in turn increases autophagy. Fasting restores your circadian rhythm to normal over time. Fasting increases nitric oxide release. Fasting restores NAD+ to healthy levels. Fasts from 36-96 h increase metabolic rate due to norepinephrine release! Telomeres are lengthened and fasting also increases anti-aging Yamanaka factors. After 72 hours or more fasted, your body recycles up to 1/3 of all immune bodies, rejuvenating your entire immune system. This helps prevent the onset of new autoimmune conditions, which develop through a leaky gut and damaged immune system. Fasting can help with MS, Depression, BPD, Autism and seizures. Thymus is regenerated, which suppresses aging and renews the immune system. The thymus also plays a vital role in fighting cancer. Weight loss from daily caloric restriction has 1/4 to 1/3 of the weight lost as lean tissue while many studies show fat loss from 36 h fasts without losing any lean tissue! The obese will lose extra tissue like loose skin while fasting, but the skinny or frail will have increased growth hormone release than the obese, which helps to make more lean tissue and reduce frailness. When you move out of MTOR your body shuts down the building blocks of the cell required for viruses to replicate. The hunger hormone ghrelin also lowers with extended fasting and rises from dieting. What breaks a fast? Anything with protein or carbohydrates in it will break a fast. Most teas and herbs are OK. Most supplements and meds will either break ketosis directly or contain a filler that will. Many meds are dangerous to take while fasting. Does fasting lower testosterone? No, it raises it when the fast is broken by increasing lutenizing hormone. Fasting also increases insulin sensitivity, which helps with muscle building. Fasts of 36-96 will not affect short term female fertility or affect menstrual cycle. They also may increase long term fertility, especially in women with PCOS. One day of fasting can cut your leptin levels in half and gets your immune system working properly again! This reduces leptin resistance, which impairs immune function. Stomach acid is reduced over time while fasting and can allow for the healing of treatment resistant ulcers. Some patients may need continued acid reduction medication while fasting. Does the body preferentially prefer glucose as a fuel? No. Except for brief periods of very intense exercise, your body mainly burns fats in the form of free fatty acids. Your brain also prefers to burn ketones at a rate of around 2.5 to 1 when they are available in equal quantity to glucose. Fasting stimulates the AMPK complex and activates autophagy. Autophagy (literally self eating) will cause cells to recycle damaged proteins and foreign matter such as viruses. It will can kill cancerous and senescent cells Lowering insulin via fasting virtually eliminates chronic inflammation in the body. It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency. Increased mitochondrial function also has the added benefit of increasing your metabolism, fighting infection and cancer prevention! Fasting releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth. This can help a great deal with diseases like MS, peripheral neuropathy and Alzheimers. When not in ketosis, the brain can only burn carbohydrate, which produces a great deal of damaging ROS the brain has to deal with. Fasting also increases telomere length, negating some of the effects of aging at a cellular level. When you fast, this stimulates apoptosis in senescent or genetically damaged cells, destroying them. Senescent cells are responsible for many of the effects of aging and are a root cause of the development of cancer. A fasting mimicking diet for 3-5 days in a row also provides many of the same benefits as water fasting. FMD usually has 200-800 calories, under 18 g of protein and extremely low carbs. Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia. They also help with dementia and many other issues even if you take them while not fasting! Glycine and trimethylglycine can also be useful supplements while fasting that won't break ketosis and have many benefits. Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or certain forms of hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution as it could lead to ketoacidosis. If you experience extreme symptoms of some kind, especially dizziness or tremors, then simply break the fast and seek advice. Resources: www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ www.ncbi.nlm.nih.gov/pmc/articles/PMC1413655/ www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/ pubmed.ncbi.nlm.nih.gov/31877297/ n.neurology.org/content/88/16_Supplement/P3.090 pubmed.ncbi.nlm.nih.gov/31890243/ pubmed.ncbi.nlm.nih.gov/2518860/ clinical.diabetesjournals.org/content/36/3/217 www.ncbi.nlm.nih.gov/pubmed/23876457 pubmed.ncbi.nlm.nih.gov/6859089/ www.ncbi.nlm.nih.gov/pubmed/10232622 pubmed.ncbi.nlm.nih.gov/33530881/ www.arcjournals.org/pdfs/ijrsb/v3-i11/7.pdf onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2265.2005.02288.x academic.oup.com/ajcn/article/81/1/69/4607679 www.ncbi.nlm.nih.gov/pmc/articles/PMC7607739/ www.collective-evolution.com/2017/05/16/study-shows-how-fasting-for-3-days-can-regenerate-your-entire-immune-system/ pubmed.ncbi.nlm.nih.gov/7714088/ www.ncbi.nlm.nih.gov/pmc/articles/PMC6407435/ www.ncbi.nlm.nih.gov/pmc/articles/PMC6141719/ pubmed.ncbi.nlm.nih.gov/20921964/ pubmed.ncbi.nlm.nih.gov/25909219/ pubmed.ncbi.nlm.nih.gov/29727683/ www.ncbi.nlm.nih.gov/pmc/articles/PMC5895342/ pubmed.ncbi.nlm.nih.gov/23707514/ www.ncbi.nlm.nih.gov/pubmed/24905167 www.ncbi.nlm.nih.gov/pmc/articles/PMC6526871/ www.ncbi.nlm.nih.gov/pubmed/25686106 pubmed.ncbi.nlm.nih.gov/21410865/ www.ncbi.nlm.nih.gov/gene/25712 www.sciencedirect.com/science/article/pii/S1931312809002832 pubmed.ncbi.nlm.nih.gov/15522942/ faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.819.10 www.biorxiv.org/node/93305.full www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart www.ncbi.nlm.nih.gov/pmc/articles/PMC7093158/ www.cell.com/molecular-cell/fulltext/S1097-2765(18)30605-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276518306051%3Fshowall%3Dtrue pubmed.ncbi.nlm.nih.gov/28235195/ www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/ www.nia.nih.gov/news/research-intermittent-fasting-shows-health-benefits medicalxpress.com/news/2022-10-treatment-pulmonary-fibrosis-focus-telomeres.html www.ncbi.nlm.nih.gov/pubmed/10859646 www.cell.com/cell/fulltext/S0092-8674(19)30849-9 www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/ pubmed.ncbi.nlm.nih.gov/23408502/ www.amjmedsci.org/article/S0002-9629%2815%2900027-0/fulltext europepmc.org/article/MED/22402737?javascript_support=no www.nejm.org/doi/full/10.1056/NEJMoa012908 pubmed.ncbi.nlm.nih.gov/27569118/ www.cell.com/cell-metabolism/abstract/S1550-4131(15)00224-7 repository.upenn.edu/cgi/viewcontent.cgi?article=1537&context=edissertations www.ncbi.nlm.nih.gov/pmc/articles/PMC1779438/ www.nejm.org/doi/full/10.1056/NEJMc2001176 www.sciencedirect.com/science/article/pii/S0005272806000223 www.clinicaltrials.gov/ct2/show/NCT04375657 pubmed.ncbi.nlm.nih.gov/20102774/ This list compiled over years of research by the user known as Pottenger's Human on youtube. Feel free to copy and paste this anywhere you like, no accreditation needed! My community tab will always contain an updated version of this list of fasting benefits. I also have playlists on fasting and health topics.
Extended fasting actually lowers your immune system, increases muscle degeneration, causes the body to go into starvation mode which lowers your metabolic rate, starves your (healthy) gut bacteria, causes deficiencies, raises cortisol, etc. I'd only do time-restricted eating (some call it intermittent "fasting") like 16/8 and suggest improving your nutrition instead of doing (extended) fasts. That is more healthy and sustainable.
Pure nonsense. Your metabolism goes up on fasts up to 96h. You gainmore lean tissue from doing ADF for 6 months. You regenerate white blood cells with every fast, which repairs immune system. All in the links. Now stop repeating nonsense. @@xnoreq
Just got diagnosed T2D and I really needed to hear something positive- I have some direction now. In 2 weeks I’ve applied his advice and gone from worse glucose at 370 and now best at 118. It’s leveled out around 150 - I’m relieved. 😊
Jason is too kind. This issue is not being too busy, or medical training or being trapped in a silo. It's greed and power. Pure and Simple. Follow the money. Always.
I’m reading his book and learning so much.. things I didn’t learn in nursing school.. I have bought his cookbook as well to help me cook properly.. thank you dr. Fung.. I understand so much better.. I’ve been type 2 diabetic for 25 years and had a widow maker heart attack recently and I survived.. I had a 2% survival rate.. have a second chance…I’ve tried so many diets prior and unsuccessful.. now I’m going to continue to read your book and do this right!
Brilliant conversation. Dr. Fung makes it easy to understand and provides the ultimate tools for success. Thank you Jesse for having Dr. Fung as your guest once again.
Jesse great interview watch both videos. You ask all the right questions! You listen and give Dr Fung a chance to respond. I love all your comprehensive videos. Easy to watch and just packed with cutting edge content.Cant thank you enough.
Super info. One month ago I was told I have type 2 diabetes with glucose at 20.93 and prescribed metformin. I said no thanks to that and researched now high protein low carb diet. Nasal Breathing for nitric oxide intermittent fasting. Walking daily, yesterday glucose at 5.7. Yuhuuu. It’s a long journey but great channels like this help so much. Best of luck to all
Dear Jesse, What is the expected progression in the reversal of diabetes? How low can we expect HBA1c to go? Over what duration? For a given regimen (low carb, intermittent fasting), does it plateau and not drop beyond a point? Can you please do a podcast on this?
I don’t know but I do know that I went from a prediabetic hbh1c to normal in one year. I did it by cutting down carbs and especially by reducing added fructose. According to the uk nhs website we should eat no more than 30g added fructose or sucrose per day. That’s because your liver can’t process much fructose. The sugar bowl analogy is pertinent here as excess sugar is converted into liver fat. That leads to fatty liver and thence awful metabolic illness including diabetes,blood pressure issues and all the rest. During my year of combat I ate a lot less sucrose than that and carbs generally about 70g/ day. If one is actually diabetic it’s probably best to cut down carbs and sugar more drastically as that’s metabolic disaster.
Read the research of Dr. Unwin. It all depends how severe is your diabetes and how long you have suffered it. If you are just prediabetic or have just been diagnosed as a diabetic, you can reverse your diabetes in 3-6 months with a very low carb diet (
I have watched couple of your videos and what I really like is your questions to your guests. Each of your video certainly clarified a bit more on diabetes problem.
Intermittent fasting helps me to reduce my BP and glucose levels. I also break my fast with protein rich meals in order to continue keeping my glucose levels low. My second meal after fasting will be low-carb. I also drink green/herbal tea while fasting
Nobody other than Jesse knows to get the best out of Gems like Dr Lustig andDr Ekberg and Dr Jason Fung Very very educative for optimal health Thankyou
This is an amazing podcast.... everyone should take the time and have the PATIENCE to stay and listen...the questions are the layman's and make it interesting.
I’m wanting to make sure I understand what the doctor is saying. It sounds like he’s saying that the issue is there is too much glucose in the cells and raised blood sugar comes about by not being able to put any more glucose into the cell. To me, though that would mean that once you got the cell down to the normal level of glucose that things would be reversed 100%, but what I’ve seen is once you break the system it never seems to go back to normal, even though you do fast and bring the glucose levels down in the cells, so as soon as you eat a moderate amount of carbs the blood glucose shoots above normal again. Why is it that once the blood sugar goes too high you have to stay on a low carb lifestyle for the rest of your life? I would like to hear him talk about that.
Not more horrifying than the stats we already have: 50% of the US population is obese and half of those morbidly so. In 2015, the average BMI was 29 which also put it into the top 20 most obese countries in the world, behind a number of countries whose names most Americans could not even spell.
I genuinly reversed my diabetes by doing fasting (24 and 36 hour fasts) and going on the carnivour diet (this diet seriously got rid of my psorisis and low energy aswell) Im not trying to push anything this honestly worked for me. Im just saying people should give it a go and see if it works for them.
Thanks Jesse & Jason. GREAT CONVERSATION by two wonderful 🇨🇦 😀. (Followed dr Fung back. 6 ish years ago, when I lost my 65 lbs on keto. Did some multiple day fasting and 2 meals IF a number years ago. I had pretty normal blood sugar). I’m actually back on 50 total carbs, (with my grassfed meat & their fats, low oxalate carbs)and still on ETRF …18 hrs IF with 2 satisfying large meals a day. Hovering around 1750 calories. I just feel better at 🙋🏻♀️ 66 yrs old.
After I lost those 65 lbs, I self experimented and increased my carbs, inc fruit. I felt very inflamed. I’m happy to be back on keto with animal meats and fats as my base. Plus low oxalate carbs. Shutout also to Sally k Norton
After 6 months of being on a keto-style diet. I have lost 35 pounds. My A1c has gone from 6.1to5.7. Was hoping to be doing a little better. I think it may have been because I did start adding some lowest-carb food and started having 3 meals a day again. As of today, I am going back to 2mad. See what my results are on my next A1c test. Thank you for the information and advice. How do I get my Ontario doctor to follow your advice?
Jesse first off thank you for what you do.. wish Dr. Fung was my doctor..love this interview learned a bunch..I’ll have to watch it again..thank you both! 💝💝
No it's not! It's great to exercise and healthy. Especially hiit, resistance training and sprints. But it's the low carbs diet that reverses diabetes!!
Exercise does little in terms of burning calories from excess food intake unless you do a lot of it and then you get even more hungry... Improving nutrition has to be a diabetic's #1 priority ... it's usually also the main reason they developed diabetes in the first place. Get rid of empty calories (like sugar) and refined carbs (like sugar). Replace them with more nutritious foods that also have less calories. This is easy to do and will take you 80% of the way. Hard exercise is the remaining 20%.
@@debbiereyes1688 Yeah, this only burns about 40g of carbs and if you ate a small amount of carbs to begin with then this will result in cravings. And if you lose weight doing this then a lot of it will be from water and muscle and not body fat. Besides, if you do this consistently after every meal then this sums up to _a lot,_ many hours per week, proving my point. I do not see how this is sustainable for someone that already struggles with his/her grocery list.
A very big thank-you for this video, very informative and really helped me understand many things about how to proceed. Doctor Fung is really interesting and qualified. You did a great job interviewing him! Thanks again.
👍👍Enjoyed the interview. Was hoping Dr. Fung would have emphasized more the importance of nutrients in allowing the cell , via the mitochondria, to process glucose (and fatty acids) into energy. This then might have led to a discussion how foods are grown and the importance of nutrient dense foods providing the satiety the body needs to stop unnecessary eating. A great first step and look forward to Dr. Fung’s journey into this realm. Loved the restaurant and sugar bowl analogies 😊
The cholesterol in the atherosclerotic plaques comes from the blood clots that form where the artery lining has been damaged. Blood clots contain red blood cells. Red blood cell membranes are 40% cholesterol.
Good day Dr Fung i was diagnosed in 2022 and living on meds but i stop take them i was at 10.7 in two month i loose 20 lb know am 6.6 you change me life big time thank for the information great work.
❤❤❤❤3:30 weird infections when there is so much sugar available in different tissues, eg your foot. But where in the tissue is the sugar? In the muscle celks? In the blood...in the excess interstitial fluid...lymph. Dr Fung is always very vague about this
Everywhere. Fung seemed confused on this point. Inflammation is not triggered because "bacteria love sugar" but because increasing inflammation is the body's main defense against insulin. Why would the body need to defend itself from its own insulin? Well, when the cells are full then the body cannot store any more without damaging the cells, but if there is excess blood glucose then the body also produces more insulin which promotes storing this excess in the cells, so the body triggers inflammatory processes that reduce the "effectiveness" of insulin. This can be described as "insulin resistance" - a term that these people like to throw around a lot. Chronic inflammation all over the body taxes the immune system, making it easier for pathogens to enter the body, multiply and do their thing. That's why you get infections especially in parts of the body that not well protected by thick skin (such as the ear) or are subjected to more pathogens (such as feet).
@@xnoreq thank you... I have more questions, but I need to think about them carefully. As you say, a lot of concepts get thrown around,till they in themselves become a convenient form of 'pat answer' when the person don't actually know the answer or mechanism. Pat answers are a form of gaslighting.
There are people that changed their diet but still slow results . I went from an A1C of 14 down to a 9.1 in 6 months. Shed a little weight (20 lbs) 140 to 120 Now what ? Still taking insulin Humalog and Semglee 🤔. I’m in pain 24/7 . Type 2 for 5yrs 57 yrs and 1stroke 🤔
Dr Fung was the first one on youtube for me when I started low carb and IF and reversing my PCOS/IR. Need some help to understand my labs (low glucagon) now. My GP is nice and open minded but don’t know this stuff… Both insulin (4,2) and glucagon (7,8) are low at 8 AM; Glucose 104. a1C 5,2 c-peptide 1,8. HDL 90. I am mostly carnivore and OMAD. Have lots of stress in life🙇🏼♀️.Hashimoto (not so bad on a paper). Low energy esp. in the morning. Help please 🤓
8min in. It’s less about glucose and more about visceral fat. The more visceral fat the smaller the sugar bowl. So yeah, you can just quit filling up the sugar bowl by consuming less carbohydrate as a “hack”, but the actual problem is visceral fat. Improving that makes your bowl bigger. And no, carbs did not get you there, overconsumption did, likely from junk food.
Two minutes in Jason Fung states that when the sugar bowl gets full that this represents the inability of the body to store sugar(glucose) and then that surplus glucose spills into the blood. He then goes into the standard low-carb solution of cutting carbohydrates. Actually, the body has a tremendous ability to store glucose, especially as fat. It is true that a person can "over-eat" carbohydrates, especially high glycemic processed foods. Blood glucose levels can be controlled with low glycemic foods and dietary fiber.
In 2011 my husband was diagnosed in 3 hospitalsor type2 diabetes. We had acupuncture and moxibustion and in the 6th month, another doctor said he was not diabetic. Reversal was then not considered but we told our friends that Tradl Chinese medicine reversed his condition.
An excellent interview (apart from the repeated use of the tautological "period of time"). Pity it's more than an hour in length. This may discourage some potential watchers or others from watching the programme to its end.
Hi Jesse - I love the podcast. I have a request for you - the next time you have someone like Dr Lustig or Dr Fung on, can you ask them to discuss this situation. Type 2 has a long and steady morning glucose rise ( dawn phenomenon) despite fasting on a 16-8 schedule. Eating something like a couple hard boiled eggs stops the rise better than a 20-30 minute walk. When I stop the duration and magnitude of the morning rise by eating, it brings my average daily glucose down from 130-135 to around 115. Which is better for the long term control of blood sugar with the goal of reversing type 2 - 16:8 intermittent fasting or minimizing the Dawn phenomenon? FYI, the information I have learned from listening to your podcast has helped be make life style changes and reduce my A1C from type 2 to pre-diabetic. I am within striking distance of dropping it to 5.6 or less. Thanks!
He has explained the mechanism. However , the underlaying question is why the same cells when you are at age of 18 allows in more and more sugar inside and glucose levels remains normal as opposed to when you are at age of 50. The code has been broken by some scientists at Harvard. I would suggest Dr. Fung to look into latest research on aging biological pathways such as Sirtuins , AMPK , and mTOR.
Dr. Joseph Kraft, father of the insulin assay test, who kept records of 15,000 patients said that anyone with heart disease and not diagnosed with diabetes has diabetes in situ and just hasn’t been diagnosed.
Was nice to listen in on this conversation. I have learnt a lot about my type 2 diabetic condition. Iam 62 years, small i get hungry fast. What advise do you give me to start fasting to reduce sugar level
Thanks for watching this episode with Dr. Jason Fung! If you're finding it valuable, please vote by hitting the LIKE button on the video. This lets me know what type of guests to book for upcoming shows. Thanks! -Jesse 💙
P.S. How do you like our new opening animation? :)
Thanks for your reply. I don't think the animation is necessary. The words of the guest generate sufficient interest.
Hello @JesseChappus, how about insulin resistance and pcos?
Hello @JesseChappus how about insulin resistance and pcos please?
Metabolic experts - Dom D´agostino Thomas Seyfried Jeff Volek Robert Lustig
P0
He is a genius. I have been following him for the past 6 months and I have applied his advice and reversed my pre-diabetic completely
Amazing news, thanks for sharing 💙
How ?
Could yousay how please ,,what did you eat
Basically I followed his advice on intermittent fasting . Eliminated all processed carbohydrate. Basically eating within six hour window 12 noon and last meal at 6pm. I was on a very low carb high fat protein diet. MY A1C went down from 6.5 to 4.66
@@thomasyeboah8036 glad to hear you're positive out come ,, and we need to hear so we can attempt to get the same outcome
Dr. Fung, Dr.Lustig, Dr. Ekberg are my heroes. They have literally changed my life.
Ekburg isn’t in the same class.
@@BillyHannon14 yes I know, but he says the same stuff as the others and his advices are more practical as well. I really don't care what kind of title he has.
Dr Berg
@@Phoenix-oj8ul Well, eating properly I don't need to take any supplements.
Ekberg is definitely a teacher.. amazing too!
When i was diagnosed as diabetic in November i found Dr Fungs videos about fasting. Got my A1C down from 8.2 to 4.8 in 6 months and off all meds. He literally saved my life.
What did you change your diet to?
Dr Fung is the KING of analogies. Fantastic interview, Jesse.
Thank you!!! 💙
I appreciate your interviews. You ask great questions.
Through Doctor Jason Fung and doctor eric berg I managed to reverse my pre diabetic condition. I used to be 220 lbs but now I'm 170 lbs actually I was extremely close to becoming a life long type 2 diabetic because of my over weight,extremely high sugar diet, sedentary life style. I thank both these doctors they saved my life from an impeding disaster
What is symptoms you feel on prediabetes
@@anujbhardwaj3960I was pre diabetic too, and my diagnosis was a surprise and a disappointment for me. I did not experienced any major signs and symptoms that indicated a growing problem. However, if you pay attention to your body and look closely at your skin and other subtle things that we tend to blame on work, age and other things; it may be a metabolic problem. I was 66, and I though that my problems were related to age and extreme levels of stress (this is a risk for developing dm). Here are some things that now I identify as sings and symptoms of pre and full diabetes; dark spots on my calfs and big toe nails, becoming easily tired, bone aches with joints hurting the most, increased urination at least one trip in the night, increased insomnia (always being a light sleeper), skin dryness, cracking heels. I was not overweight and never been, so weight has never been a problem for me. Also emotional distress, anxiety; these were upsetting because I always have had good emotional balance. Everything else was normal per lab results. My only abnormal was my A1C. I hope this helps, but we are all different and you may develop these or other symptoms, also your age may make a difference. I am back to normal, and these symptoms have disappeared. I hope I helped some.
@@anujbhardwaj3960, that's the thing. You usually feel fine.
What foods did u eat and how long did it take to loose the weight?
@@annettesanchez4425 high protein food both veg and non veg,fiber,avoiding refined carbs,carbonated drinks and finally exercise along intermittent fasting all of these worked out very well for my in losing 80 lbs of extra weight
Dr Jason Fung is like a saviour. He educates in simple words that people who didn't go to medical school could understand root cause of the issue and take matters of health in their own hands.Much love !!❤
🎯 Key Takeaways for quick navigation:
00:00 🩸 *Insulin and Glucose Dynamics*
- Insulin pushes glucose into cells until a limit is reached, causing high blood glucose and leading to type 2 diabetes.
02:20 🍚 *Analogy: Sugar Bowl and Body's Glucose Storage*
- The body stores glucose similar to a sugar bowl, but excess causes overflow into the blood, leading to type 2 diabetes.
03:13 🏛️ *Impact of Diabetes on Organs*
- Diabetes affects various organs, causing heart problems, strokes, cancers, blindness, nerve damage, kidney damage, and more.
04:25 🔄 *Insulin Resistance and Blood Glucose Regulation*
- Insulin resistance occurs when cells resist the effect of insulin, hindering glucose entry into cells and leading to elevated blood glucose.
08:03 📊 *Hyperinsulinemia and Glucose Overflow*
- Hyperinsulinemia occurs when the body uses extra insulin to force glucose into cells, resulting in normal glucose levels but high insulin levels.
11:40 🩺 *Identifying Early Signs of Insulin Resistance*
- Metabolic syndrome indicators, including high blood pressure, high triglycerides, low HDL, and abdominal obesity, can signal early insulin resistance.
13:34 🛑 *The Misconception of Lowering Blood Glucose*
- Lowering blood glucose alone doesn't improve health; focusing on insulin levels is crucial, as seen in studies with near-normal glucose levels worsening diabetes.
16:31 💡 *Onset of Chronic Diseases in Insulin Resistance*
- Chronic diseases can begin much earlier in the insulin resistance spectrum, preceding the official diagnosis of type 2 diabetes.
18:33 🧐 *Detecting Diabetic Damage Before Diagnosis*
- Protein in the urine can indicate diabetic kidney disease, even before an official diagnosis of diabetes, highlighting the importance of early detection.
20:09 💔 *Insulin's Role in Cardiovascular Diseases*
- Elevated insulin levels contribute to atherosclerosis, narrowing arteries, and increasing the risk of heart attacks and strokes.
22:11 🩸 *Insulin and Heart Disease Focus*
- Insulin contributes to inflammatory responses and smooth muscle proliferation in arteries.
- Cholesterol, while a factor, is not a major one in heart disease compared to smoking and diabetes.
- Studies emphasize smoking and diabetes as significantly increasing the risk of heart disease.
24:30 🔄 *Latency Before Type 2 Diabetes*
- There's a latency period before type 2 diabetes manifests, during which insulin resistance and elevated insulin contribute to heart disease.
- High insulin and inflammation play crucial roles in heart disease, often overshadowed by cholesterol concerns.
- Emphasis on the reversibility of diabetes as a risk factor, unlike factors such as age and genetics.
28:25 🚑 *Insulin Resistance and Heart Disease Timing*
- The discussion on the timing of heart disease concerning insulin resistance before diabetes diagnosis.
- Heart disease can occur before diabetes, and the severity varies based on individual factors.
- Diabetes significantly contributes to heart disease, and its reversibility is a key focus.
31:40 🔄 *Accumulation of Fat in the Body*
- Insight into the process of de novo lipogenesis and the body's response to excess glucose.
- Explanation of how the body accumulates fat in the liver, abdomen, and pancreas, leading to metabolic issues.
- Increased abdominal girth and fatty pancreas are indicators of excessive glucose-related problems.
38:22 🍽️ *Treatment Approaches: Controlling Glucose Intake*
- The effectiveness of low-carbohydrate diets in managing and even reversing type 2 diabetes.
- Recognition of the glycemic index's impact on blood glucose levels.
- Dr. David Unwin's success with patients achieving drug-free remission through carbohydrate reduction.
40:41 ⚖️ *Treatment Approaches: Calorie Restriction*
- Exploring ultra-low-calorie diets as a strategy, cutting down not just carbs but overall calories.
- Highlighting the effectiveness of very low-calorie diets, around 800 calories a day, albeit with potential compliance challenges.
- Understanding how reducing all calorie sources, including fats, prompts the body to burn glucose.
42:33 🕰️ *Treatment Approaches: Intermittent Fasting*
- Intermittent fasting as a method to allow the body to burn excess glucose during fasting periods.
- Comparing intermittent fasting to a strategy of zero calories for specific time intervals.
- Stressing the importance of educating individuals on the purpose and benefits of intermittent fasting.
43:43 🍽️ *Methods to Reverse Insulin Resistance*
- Three effective treatments: low carb, intermittent fasting, and calorie reduction.
- Multiple approaches available, including low carb, cutting calories, and intermittent fasting.
44:40 🌾 *Low Carb Approach*
- The significance of low carb in reversing insulin resistance.
- Ketosis as an ultra-low carbohydrate diet, its benefits, and measurement.
- Flexible approaches to low carb, not strictly requiring ketosis.
47:26 📉 *Calorie Reduction and Nuances*
- Dr. Fung introduces calorie reduction as a tool against insulin resistance.
- Critique on the conventional calorie reduction approach and its limitations.
- Highlighting the importance of understanding the root cause of excessive calories.
58:41 ⏰ *Intermittent Fasting as a Powerful Tool*
- Gradual approach to intermittent fasting, starting with cutting out snacks.
- Flexibility in fasting duration based on individual needs.
- Fasting's impact on burning excess glucose and its role in controlling type 2 diabetes.
01:00:56 🔄 *Fasting vs. Calorie Restriction on Basal Metabolic Rate*
- Fasting's impact on basal metabolic rate compared to calorie restriction.
- Preservation of metabolic rate during fasting due to increased sympathetic tone.
- The advantage of maintaining a higher metabolic rate in weight loss efforts.
01:03:50 💪 *Preserving Muscle Mass during Intermittent Fasting*
- Addressing concerns about muscle mass loss during intermittent fasting.
- Importance of muscle mass and its preservation during fasting.
- Fasting as a method to preserve muscle mass, especially when combined with low carb.
01:04:04 🏋️♂️ *Addressing Muscle Mass Concerns During Fasting*
- Fears about muscle loss during fasting are often overblown.
- Muscles respond to usage; the concern about losing muscle mass due to fasting is not well-founded.
- Measurement methods, such as bioimpedance, can misinterpret changes, leading to unnecessary concerns.
01:08:54 🤔 *Utilizing Strategies for Type 2 Diabetics Without Weight to Lose*
- For underweight individuals with type 2 diabetes, weight loss might not be the primary goal.
- Low carb and intermittent fasting can be effective tools without necessarily causing significant weight loss.
- Low-calorie diets, while theoretically effective, often face practical challenges and are less successful in real-world scenarios.
Made with HARPA AI
Thanks a ton for the key takeaways :)
Great job! Thousands thanks!
Very nice, thank you robot overlords
Thanks. U made it easy to understand
Thank you. This was immensely helpful.
Dr. Fung explains things very well. Thanks for this great interview.
The overall reason on excessive carbs is we were taught by the market and education to reduce fats not carbs. That is why we have excessive sugar.
Switching to animal based diet (Grass finished beef, organs, raw dairy, fruit, raw honey, cook only in butter/tallow) 6 months in I've lost 40 pounds and have a 6 pack. I also completely cleared my pre-diabetic & autoimmune conditions. And I have diabetes in both sides of my family. Nutrition is #1
Yeah and now you got chronic diarrhea, insomnia, hair loss, and loose teeth 😅
@keylanoslokj1806 you speaking for yourself? Lol I have a full head of hair, 2 healthy poops a day, sleep 8 hours every night (I sleep by 11 usually zzz) my skin is glowing and I train hard 6x a week, my muscles have never grown and recovered so fast in my life. Keep trying to cope with your unhealthy lifestyle buddy! Hope you can make a change. Xoxo
@keylanoslokj1806 I'd love to see what kinda diet you live on. to sustain any of what I said involves heavyyyy plant intake. You'd have to eat soooooooo many plants and lentils to reach 200g of protein a day. Compared to me eating a nice steak, or ground beef, few eggs, grass finished whey isolate, yogurt & milk. All natural baby. All bioavailable and nontoxic. How do people who eat out of frozen boxes argue health I'll never understand. 🤡
@@LilOtter lol poor thing. You don't even eat fruit
@keylanoslokj1806 lmao I love it when people don't read and just spew out of anger in the comments, here I'll help you out. What did I say after dairy? What was it I eat? 🤔
Fasting can not only burn off liver fat and make room for insulin to do its job but it can even help restore beta cell function! Some benefits of doing occasional extended fasting: High blood pressure is lowered to normal levels very quickly while fasting. Fibrosis/scarring is reversed over time, including in the heart and lungs.
Fasting increases T cell production and regenerates the thymus. T cells are vital in fighting cancer, autoimmune disease and infections but as we age the thymus stops making as many of them. Fasting releases stem cells, which then can become new T cells. Fasting also releases growth hormone, which regenerates the thymus itself, which aids this process!
Fasting stimulates phagocytosis, the ingestion of bacteria, plaques and viruses by the immune system. This will also remove any spikes, whether natural or unnatural in origin!
Blood clotting is reduced and blood clots and arterial plaque are reabsorbed into the body.
Blood sugar and insulin are lowered when fasting, allowing white blood cells to move more freely throughout the body and do their job.
Vitamin D plasma levels are increased as fasting improves metabolic health, and vitamin D in turn increases autophagy.
Fasting restores your circadian rhythm to normal over time.
Fasting increases nitric oxide release.
Fasting restores NAD+ to healthy levels.
Fasts from 36-96 h increase metabolic rate due to norepinephrine release!
Telomeres are lengthened and fasting also increases anti-aging Yamanaka factors.
After 72 hours or more fasted, your body recycles up to 1/3 of all immune bodies, rejuvenating your entire immune system. This helps prevent the onset of new autoimmune conditions, which develop through a leaky gut and damaged immune system.
Fasting can help with MS, Depression, BPD, Autism and seizures.
Thymus is regenerated, which suppresses aging and renews the immune system. The thymus also plays a vital role in fighting cancer.
Weight loss from daily caloric restriction has 1/4 to 1/3 of the weight lost as lean tissue while many studies show fat loss from 36 h fasts without losing any lean tissue!
The obese will lose extra tissue like loose skin while fasting, but the skinny or frail will have increased growth hormone release than the obese, which helps to make more lean tissue and reduce frailness.
When you move out of MTOR your body shuts down the building blocks of the cell required for viruses to replicate.
The hunger hormone ghrelin also lowers with extended fasting and rises from dieting.
What breaks a fast? Anything with protein or carbohydrates in it will break a fast. Most teas and herbs are OK. Most supplements and meds will either break ketosis directly or contain a filler that will. Many meds are dangerous to take while fasting.
Does fasting lower testosterone? No, it raises it when the fast is broken by increasing lutenizing hormone. Fasting also increases insulin sensitivity, which helps with muscle building.
Fasts of 36-96 will not affect short term female fertility or affect menstrual cycle. They also may increase long term fertility, especially in women with PCOS.
One day of fasting can cut your leptin levels in half and gets your immune system working properly again! This reduces leptin resistance, which impairs immune function.
Stomach acid is reduced over time while fasting and can allow for the healing of treatment resistant ulcers. Some patients may need continued acid reduction medication while fasting.
Does the body preferentially prefer glucose as a fuel? No. Except for brief periods of very intense exercise, your body mainly burns fats in the form of free fatty acids. Your brain also prefers to burn ketones at a rate of around 2.5 to 1 when they are available in equal quantity to glucose.
Fasting stimulates the AMPK complex and activates autophagy. Autophagy (literally self eating) will cause cells to recycle damaged proteins and foreign matter such as viruses. It will can kill cancerous and senescent cells
Lowering insulin via fasting virtually eliminates chronic inflammation in the body.
It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency. Increased mitochondrial function also has the added benefit of increasing your metabolism, fighting infection and cancer prevention!
Fasting releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth. This can help a great deal with diseases like MS, peripheral neuropathy and Alzheimers.
When not in ketosis, the brain can only burn carbohydrate, which produces a great deal of damaging ROS the brain has to deal with.
Fasting also increases telomere length, negating some of the effects of aging at a cellular level.
When you fast, this stimulates apoptosis in senescent or genetically damaged cells, destroying them. Senescent cells are responsible for many of the effects of aging and are a root cause of the development of cancer.
A fasting mimicking diet for 3-5 days in a row also provides many of the same benefits as water fasting. FMD usually has 200-800 calories, under 18 g of protein and extremely low carbs.
Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia. They also help with dementia and many other issues even if you take them while not fasting!
Glycine and trimethylglycine can also be useful supplements while fasting that won't break ketosis and have many benefits.
Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or certain forms of hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution as it could lead to ketoacidosis. If you experience extreme symptoms of some kind, especially dizziness or tremors, then simply break the fast and seek advice.
Resources:
www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/
www.ncbi.nlm.nih.gov/pmc/articles/PMC1413655/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/
pubmed.ncbi.nlm.nih.gov/31877297/
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pubmed.ncbi.nlm.nih.gov/31890243/
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www.ncbi.nlm.nih.gov/pubmed/23876457
pubmed.ncbi.nlm.nih.gov/6859089/
www.ncbi.nlm.nih.gov/pubmed/10232622
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www.arcjournals.org/pdfs/ijrsb/v3-i11/7.pdf
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academic.oup.com/ajcn/article/81/1/69/4607679
www.ncbi.nlm.nih.gov/pmc/articles/PMC7607739/
www.collective-evolution.com/2017/05/16/study-shows-how-fasting-for-3-days-can-regenerate-your-entire-immune-system/
pubmed.ncbi.nlm.nih.gov/7714088/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6407435/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6141719/
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pubmed.ncbi.nlm.nih.gov/29727683/
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www.ncbi.nlm.nih.gov/pubmed/24905167
www.ncbi.nlm.nih.gov/pmc/articles/PMC6526871/
www.ncbi.nlm.nih.gov/pubmed/25686106
pubmed.ncbi.nlm.nih.gov/21410865/
www.ncbi.nlm.nih.gov/gene/25712
www.sciencedirect.com/science/article/pii/S1931312809002832
pubmed.ncbi.nlm.nih.gov/15522942/
faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.819.10
www.biorxiv.org/node/93305.full
www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart
www.ncbi.nlm.nih.gov/pmc/articles/PMC7093158/
www.cell.com/molecular-cell/fulltext/S1097-2765(18)30605-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276518306051%3Fshowall%3Dtrue
pubmed.ncbi.nlm.nih.gov/28235195/
www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/
www.nia.nih.gov/news/research-intermittent-fasting-shows-health-benefits
medicalxpress.com/news/2022-10-treatment-pulmonary-fibrosis-focus-telomeres.html
www.ncbi.nlm.nih.gov/pubmed/10859646
www.cell.com/cell/fulltext/S0092-8674(19)30849-9
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This list compiled over years of research by the user known as Pottenger's Human on youtube. Feel free to copy and paste this anywhere you like, no accreditation needed!
My community tab will always contain an updated version of this list of fasting benefits. I also have playlists on fasting and health topics.
Extended fasting actually lowers your immune system, increases muscle degeneration, causes the body to go into starvation mode which lowers your metabolic rate, starves your (healthy) gut bacteria, causes deficiencies, raises cortisol, etc.
I'd only do time-restricted eating (some call it intermittent "fasting") like 16/8 and suggest improving your nutrition instead of doing (extended) fasts.
That is more healthy and sustainable.
Pure nonsense. Your metabolism goes up on fasts up to 96h. You gainmore lean tissue from doing ADF for 6 months. You regenerate white blood cells with every fast, which repairs immune system. All in the links. Now stop repeating nonsense. @@xnoreq
@@xnoreq Also, people should ask what fasting and low carb does to a person with thyroid disease.
Thank you for the list - much appreciated
Excellent insight 👍
Just got diagnosed T2D and I really needed to hear something positive- I have some direction now. In 2 weeks I’ve applied his advice and gone from worse glucose at 370 and now best at 118. It’s leveled out around 150 - I’m relieved. 😊
That's really awesome to hear! I'm on a little journey myself as well!
Jason is too kind. This issue is not being too busy, or medical training or being trapped in a silo. It's greed and power. Pure and Simple. Follow the money. Always.
Doctor Fung is a LIFE CHANGER!!!!!! 💯 🔥 🔥 🔥
I’m reading his book and learning so much.. things I didn’t learn in nursing school.. I have bought his cookbook as well to help me cook properly.. thank you dr. Fung.. I understand so much better.. I’ve been type 2 diabetic for 25 years and had a widow maker heart attack recently and I survived.. I had a 2% survival rate.. have a second chance…I’ve tried so many diets prior and unsuccessful.. now I’m going to continue to read your book and do this right!
This is a doctor I truly respect and I've learned so much from him!
Thank you Dr. Jason.
One of my favorite doctors
Been reading and watching Dr. Fung and trying to reverse T2D. This interview really made sense!
Dr. Fung , your’re such an intelligent guy, learned so much from you!
Brilliant conversation. Dr. Fung makes it easy to understand and provides the ultimate tools for success. Thank you Jesse for having Dr. Fung as your guest once again.
💙
Jesse great interview watch both videos. You ask all the right questions! You listen and give Dr Fung a chance to respond. I love all your comprehensive videos. Easy to watch and just packed with cutting edge content.Cant thank you enough.
Thank you so much!
Super info. One month ago I was told I have type 2 diabetes with glucose at 20.93 and prescribed metformin. I said no thanks to that and researched now high protein low carb diet. Nasal Breathing for nitric oxide intermittent fasting. Walking daily, yesterday glucose at 5.7. Yuhuuu. It’s a long journey but great channels like this help so much. Best of luck to all
Dr Fung is a genius!!!
Dr Fung is a real doctor 🎉
This is the best in depth explanation of pre-diabetes I have seen. It makes it possible to make the change necessary to revert it.
I will call Dr Fung and set up an appointment. This guy is brilliant!
Obviously, Dr. Fung has no agenda, except the truth. Very refreshing, and educational. Thank you both.
DrJason Fung He is brilliant, extraordinarily brilliant it’s all about common sense. I need this doctor to help me with my type two diabetes.
Health legend is back again with awesome information happy to see you
💙💙💙
Dear Jesse, What is the expected progression in the reversal of diabetes? How low can we expect HBA1c to go? Over what duration? For a given regimen (low carb, intermittent fasting), does it plateau and not drop beyond a point? Can you please do a podcast on this?
I would like to see that too
I don’t know but I do know that I went from a prediabetic hbh1c to normal in one year. I did it by cutting down carbs and especially by reducing added fructose. According to the uk nhs website we should eat no more than 30g added fructose or sucrose per day. That’s because your liver can’t process much fructose. The sugar bowl analogy is pertinent here as excess sugar is converted into liver fat. That leads to fatty liver and thence awful metabolic illness including diabetes,blood pressure issues and all the rest. During my year of combat I ate a lot less sucrose than that and carbs generally about 70g/ day. If one is actually diabetic it’s probably best to cut down carbs and sugar more drastically as that’s metabolic disaster.
Read the research of Dr. Unwin. It all depends how severe is your diabetes and how long you have suffered it. If you are just prediabetic or have just been diagnosed as a diabetic, you can reverse your diabetes in 3-6 months with a very low carb diet (
This is an excellent channel ❤
Thank you Jesse.
I have watched couple of your videos and what I really like is your questions to your guests. Each of your video certainly clarified a bit more on diabetes problem.
Intermittent fasting helps me to reduce my BP and glucose levels. I also break my fast with protein rich meals in order to continue keeping my glucose levels low. My second meal after fasting will be low-carb.
I also drink green/herbal tea while fasting
I love his analogies to explain things❤
Nobody other than Jesse knows to get the best out of Gems like Dr Lustig andDr Ekberg and Dr Jason Fung Very very educative for optimal health Thankyou
Thank you so much! 💙
This is an amazing podcast.... everyone should take the time and have the PATIENCE to stay and listen...the questions are the layman's and make it interesting.
Awesome video ! I love the way Dr.Fung makes complicated information easy to understand.
I’m wanting to make sure I understand what the doctor is saying. It sounds like he’s saying that the issue is there is too much glucose in the cells and raised blood sugar comes about by not being able to put any more glucose into the cell. To me, though that would mean that once you got the cell down to the normal level of glucose that things would be reversed 100%, but what I’ve seen is once you break the system it never seems to go back to normal, even though you do fast and bring the glucose levels down in the cells, so as soon as you eat a moderate amount of carbs the blood glucose shoots above normal again. Why is it that once the blood sugar goes too high you have to stay on a low carb lifestyle for the rest of your life?
I would like to hear him talk about that.
If the US population were to be tested specifically for insulin resistance, the results would be horrifying.
Not more horrifying than the stats we already have: 50% of the US population is obese and half of those morbidly so.
In 2015, the average BMI was 29 which also put it into the top 20 most obese countries in the world, behind a number of countries whose names most Americans could not even spell.
I've had insulin resistance for 15 years 😮😮
I asked my MD for a fasting insulin and they were baffled why I asked 😒
@@peachesmcqueen257 Most patients are baffled also. Save those who are tired of being sick... Or deem illness as unacceptable.
I genuinly reversed my diabetes by doing fasting (24 and 36 hour fasts) and going on the carnivour diet (this diet seriously got rid of my psorisis and low energy aswell) Im not trying to push anything this honestly worked for me. Im just saying people should give it a go and see if it works for them.
Thanks Jesse & Jason. GREAT CONVERSATION by two wonderful 🇨🇦 😀. (Followed dr Fung back. 6 ish years ago, when I lost my 65 lbs on keto. Did some multiple day fasting and 2 meals IF a number years ago. I had pretty normal blood sugar). I’m actually back on 50 total carbs, (with my grassfed meat & their fats, low oxalate carbs)and still on ETRF …18 hrs IF with 2 satisfying large meals a day. Hovering around 1750 calories. I just feel better at 🙋🏻♀️ 66 yrs old.
After I lost those 65 lbs, I self experimented and increased my carbs, inc fruit. I felt very inflamed. I’m happy to be back on keto with animal meats and fats as my base. Plus low oxalate carbs. Shutout also to Sally k Norton
After 6 months of being on a keto-style diet. I have lost 35 pounds. My A1c has gone from 6.1to5.7. Was hoping to be doing a little better. I think it may have been because I did start adding some lowest-carb food and started having 3 meals a day again. As of today, I am going back to 2mad. See what my results are on my next A1c test. Thank you for the information and advice. How do I get my Ontario doctor to follow your advice?
I listened while working out. It was productive.
Jesse first off thank you for what you do.. wish Dr. Fung was my doctor..love this interview learned a bunch..I’ll have to watch it again..thank you both! 💝💝
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Dr Jason Fung is amazingly informative.
Exercise one of the best ways to reverse diabetes. Walking 30 minutes after a meal, sprinting and strength training.
No it's not!
It's great to exercise and healthy. Especially hiit, resistance training and sprints.
But it's the low carbs diet that reverses diabetes!!
Exercise does little in terms of burning calories from excess food intake unless you do a lot of it and then you get even more hungry...
Improving nutrition has to be a diabetic's #1 priority ... it's usually also the main reason they developed diabetes in the first place. Get rid of empty calories (like sugar) and refined carbs (like sugar). Replace them with more nutritious foods that also have less calories. This is easy to do and will take you 80% of the way.
Hard exercise is the remaining 20%.
@@xnoreq The experts recommend walking 30 minutes after eating to burn off the glucose that a person just ate. 🤗
@@debbiereyes1688 Yeah, this only burns about 40g of carbs and if you ate a small amount of carbs to begin with then this will result in cravings.
And if you lose weight doing this then a lot of it will be from water and muscle and not body fat.
Besides, if you do this consistently after every meal then this sums up to _a lot,_ many hours per week, proving my point.
I do not see how this is sustainable for someone that already struggles with his/her grocery list.
@@xnoreqtrue...BUT going for a walk after meals reduces blood sugar, keeps insulin down...fact....see The Glucose Goddess
I love this man and Dr Ben Bikman
Fasting worked for me!
You're a life saver ❤
This doc is amazing
Thank you for sharing 😊👍🏻👍🏻
Thank you for this episode! This was SO informative! 2 Thumbs UP! Liked and Subscribed! And Saved for future reference.
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@@dporrasxtremeLS3
Yes I did the same, saved it to watch again for future reference.
A very big thank-you for this video, very informative and really helped me understand many things about how to proceed. Doctor Fung is really interesting and qualified. You did a great job interviewing him! Thanks again.
👍👍Enjoyed the interview. Was hoping Dr. Fung would have emphasized more the importance of nutrients in allowing the cell , via the mitochondria, to process glucose (and fatty acids) into energy. This then might have led to a discussion how foods are grown and the importance of nutrient dense foods providing the satiety the body needs to stop unnecessary eating. A great first step and look forward to Dr. Fung’s journey into this realm. Loved the restaurant and sugar bowl analogies 😊
Very, very useful information. Thank you!!!
Thank you dr Fung for sharing this health information 👍
The cholesterol in the atherosclerotic plaques comes from the blood clots that form where the artery lining has been damaged. Blood clots contain red blood cells. Red blood cell membranes are 40% cholesterol.
Thank you for making it quite simple
Good day Dr Fung i was diagnosed in 2022 and living on meds but i stop take them i was at 10.7 in two month i loose 20 lb know am 6.6 you change me life big time thank for the information great work.
Very sensible easy to understand language lots of good tips given hete
❤❤❤❤3:30 weird infections when there is so much sugar available in different tissues, eg your foot.
But where in the tissue is the sugar? In the muscle celks? In the blood...in the excess interstitial fluid...lymph.
Dr Fung is always very vague about this
It goes into all your cells and gets turned into diglycerides that make the cell nonfunctional.
Everywhere. Fung seemed confused on this point. Inflammation is not triggered because "bacteria love sugar" but because increasing inflammation is the body's main defense against insulin. Why would the body need to defend itself from its own insulin? Well, when the cells are full then the body cannot store any more without damaging the cells, but if there is excess blood glucose then the body also produces more insulin which promotes storing this excess in the cells, so the body triggers inflammatory processes that reduce the "effectiveness" of insulin. This can be described as "insulin resistance" - a term that these people like to throw around a lot.
Chronic inflammation all over the body taxes the immune system, making it easier for pathogens to enter the body, multiply and do their thing. That's why you get infections especially in parts of the body that not well protected by thick skin (such as the ear) or are subjected to more pathogens (such as feet).
@@xnoreq thank you... I have more questions, but I need to think about them carefully. As you say, a lot of concepts get thrown around,till they in themselves become a convenient form of 'pat answer' when the person don't actually know the answer or mechanism. Pat answers are a form of gaslighting.
Thanks for the perspective and easy to understand manner the doctor explains the issue of diabetes.
Thanks so much. Well explained. I finally got it.❤
There are people that changed their diet but still slow results . I went from an A1C of 14 down to a 9.1 in 6 months. Shed a little weight (20 lbs) 140 to 120 Now what ? Still taking insulin Humalog and Semglee 🤔. I’m in pain 24/7 . Type 2 for 5yrs 57 yrs and 1stroke 🤔
GOLD!
Thanks for sharing Jesse ❤👍
Dr Fung was the first one on youtube for me when I started low carb and IF and reversing my PCOS/IR.
Need some help to understand my labs (low glucagon) now. My GP is nice and open minded but don’t know this stuff…
Both insulin (4,2) and glucagon (7,8) are low at 8 AM; Glucose 104.
a1C 5,2 c-peptide 1,8. HDL 90. I am mostly carnivore and OMAD. Have lots of stress in life🙇🏼♀️.Hashimoto (not so bad on a paper). Low energy esp. in the morning.
Help please 🤓
Can someone with pcos do intermittent fasting? So many say that it is not suitable for someone with this condition.
Awesome, thank you. You ask the right questions.
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8min in. It’s less about glucose and more about visceral fat. The more visceral fat the smaller the sugar bowl. So yeah, you can just quit filling up the sugar bowl by consuming less carbohydrate as a “hack”, but the actual problem is visceral fat. Improving that makes your bowl bigger. And no, carbs did not get you there, overconsumption did, likely from junk food.
Very good information...
Fantastic conversation!
Thanks.
Insulin resistance can be felt in the hearth
One of the best analysis 🎉
Two minutes in Jason Fung states that when the sugar bowl gets full that this represents the inability of the body to store sugar(glucose) and then that surplus glucose spills into the blood. He then goes into the standard low-carb solution of cutting carbohydrates. Actually, the body has a tremendous ability to store glucose, especially as fat. It is true that a person can "over-eat" carbohydrates, especially high glycemic processed foods. Blood glucose levels can be controlled with low glycemic foods and dietary fiber.
Brilliant, thank you
Please interview Malcolm Kendrick, author of "The Clot Thickens".
thank you for this. great information.
In 2011 my husband was diagnosed in 3 hospitalsor type2 diabetes. We had acupuncture and moxibustion and in the 6th month, another doctor said he was not diabetic. Reversal was then not considered but we told our friends that Tradl Chinese medicine reversed his condition.
Wow ❤ getting amazing result
An excellent interview (apart from the repeated use of the tautological "period of time").
Pity it's more than an hour in length. This may discourage some potential watchers or others from watching the programme to its end.
28:30 fatty liver is more of the common denominator of all disease not the diabetes
I think you are right doctor
Thanks for sharing this link
Hi Jesse - I love the podcast. I have a request for you - the next time you have someone like Dr Lustig or Dr Fung on, can you ask them to discuss this situation. Type 2 has a long and steady morning glucose rise ( dawn phenomenon) despite fasting on a 16-8 schedule. Eating something like a couple hard boiled eggs stops the rise better than a 20-30 minute walk. When I stop the duration and magnitude of the morning rise by eating, it brings my average daily glucose down from 130-135 to around 115. Which is better for the long term control of blood sugar with the goal of reversing type 2 - 16:8 intermittent fasting or minimizing the Dawn phenomenon? FYI, the information I have learned from listening to your podcast has helped be make life style changes and reduce my A1C from type 2 to pre-diabetic. I am within striking distance of dropping it to 5.6 or less. Thanks!
Thanks
Great interview. I want to reverse my Type 2 diabetes
He has explained the mechanism. However , the underlaying question is why the same cells when you are at age of 18 allows in more and more sugar inside and glucose levels remains normal as opposed to when you are at age of 50. The code has been broken by some scientists at Harvard. I would suggest Dr. Fung to look into latest research on aging biological pathways such as Sirtuins , AMPK , and mTOR.
Dr. Joseph Kraft, father of the insulin assay test, who kept records of 15,000 patients said that anyone with heart disease and not diagnosed with diabetes has diabetes in situ and just hasn’t been diagnosed.
Was nice to listen in on this conversation. I have learnt a lot about my type 2 diabetic condition. Iam 62 years, small i get hungry fast. What advise do you give me to start fasting to reduce sugar level
My triglycerides dropped from 212 to 71 doing Ketovore diet. Total cholesterol is now normal. Lost 40lbs in about 6 months. Feeling great!
Fiber regulates blood glucose slows down the absorption of sugar. Lots of daily Fiber ❤
Awesome 👍
Thank you 😊
It the question is: What do I do when I have out of control blood glucose, while I fast, etc. How high my blood runs, I’m doing irreparable damage.
Thank you
Thanks for the video, please ask dr Jason how to lowered creatinine in a natural way
Excellent show, is there a link to the change for the diabetes association saying its reversible? Thank you
Some persons are not overweight and so activities for weight-loss is not for them. How can these diabetics be helped?
Watch till the end :)
No mention of excercise as a tool with the other 3??
Is there a test to check for fatty liver? Thanks for the video.
Yes blood test and ultra sound