This is HIDDEN TALENT of Your Heart: Frank Starling Mechanism || Length-Tension Relationship

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Frank-Starling Mechanism of the Heart || Length-Tension Relationship for Muscle:
With the increasing venous return, the end-diastolic volume increases. This results in increased stretching of ventricular musculature. Due to the length-tension relationship, the increased stretching results in an increased force of contraction. So stroke volume is increased. Thus with increasing venous return, the stork volume increases. The mechanism behind this is that with increased stretching, the overlapping between actin and myosin becomes more optimal and also the distance between the actin and myosin decreases. This increases the cross-bridge interaction. So the force of contraction increases.
Dr Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.

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[@user-sq3ls6sj7i]

What do you mean by initial length of muscle? The stretched one??
When we say initial length of cadiomyocyte, do we mean the ones during edv?

[@NonstopNeuron]

Yes

[@NonstopNeuron]

The length at the beginning of (or you can say before) the contraction.

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