Pacemaker potential | Cardiovascular (CVS) Physiology mbbs 1st year
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- Опубликовано: 19 авг 2024
- Physiology lecture on pacemaker potential is also known as 'nodal action potential'
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Watched about several videos read several articles but your video do the job of making me understand thanks plz make more videos
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wasted an hour reading the book😞, this 8 minute video cleard everything
Book reading never a waste. But I am glad I was of help Hope my other videos help you too.. Best of luck
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Comment below: Why SA node has highest rate of impulse generation among autorhythmic cells ? Answer lies in the pacemaker action potential....
cells in the SA node have a higher conductance for sodium ions, so they continually fire leading to more frequent action potentials
Yes, the rate is higher than other pacemaker cells like AV node (they also have pacemaker potential), because the prepotential slope is steeper in SA node because of higher conductance
@@PhysiologyOpen it was a good video, thank you
@@iazahussainzz Thank you, appreaciation helps
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Ma'am you makes it too easy to understand 🙏🙏🙏 ma'am can you upload a video about ANS distribution on heart and controlling the heart (sympathetic and parasympathetic nerve fibre) pls ma'am 🙏
Thanks for appreciation. Will try to upload.
Mam very good explanation
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amazing maam! new subscriber :)
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If the pottasium ions are going out of the Membrane then how are they recovered?? Won’t they be finished
Movement of very few ions in the range of 1/300000..causes changes in membrane potential. Moreover, sodium potassium ATPase always works and with change in any ionic concentration, it starts working even faster
Superb explanation mam
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At the end of phase 3 , the potassium has moved outside the cell, also sodium and calcium has moved inside the cell. So, how does the next cycle of action potential generate?
Can anyone explain please.
NaCaATPase moves Ca out of the cells. Na K ATPase throws Na out and brings K in
@@PhysiologyOpen thanks a lot, mam. ✨
😊
How do Ca2+ ions get out of that cell?
Ca2 ATPases...and sodium calcium exchanger
Mam, please can you do video on regulation of cardiac and respiratory system please mam?
Yup will do, it will take some time though...already have a series of videos lined up
Can you give your link for mechanism of heart rate which you tell in this video,( you tell it when you tell about cAMP and funny channels)
ruclips.net/video/w7UozvV8Kf0/видео.html
@@PhysiologyOpen thank you madam
6:00 mam why it's called hyperpolarized hcn since it's too moving towards positive or it's behaving like funny current..
It opens when membrane is hyperpolarized
Please answer me , the funny channels are permeable to sodium and potassium ions in the the same time ,,,,so the funny current is a complex of sodium and potassium ions current ,sodium inward ,but what about potassium,inward or outward ,please answer,I really need your help.
Potassium moves outward
@@PhysiologyOpen Thank you very much mum🥰🙏🏻🙏🏻🙏🏻🙏🏻
That funny current explanation.... Ohh God.... I can't forget that.... HCN channel....
Great...keep going 😊
❤❤❤❤
😊❤️
What about contractile cells graph ?Madam ...
Have to make that video
hi
on which resources did you make this video ? and what makes the cycle to repeate itself ?
didn't the Na+ and Ca+ got inside and the K+ went outside ? How is that repeated ?
Resources used for all videos
Basic: Guyton and Ganong
Above them: Sherwood
Neuroscience over and above: Kandel
Hematology: Wintrobe
Give references books for these lectures please i beg
For all lectures Guyton and Ganong
what is the fate of sodium entering during the prepotential? Phase 4
Fate means? Whatever sodium enters is thrown out by sodium potassium ATPase
Wasn't depolarization at phase zero with T-type calcium current?
Yeah true...so what’s the question?
But L-type calcium that raises from -40 mV to +10 mV
That’s also depolarisation. Depolarisation is any change in potential towards positive..when it crosses threshold it is action potential (which is always depolarisation)
Understood. Thank u so much mam 😊
Hello mam. There is a sentence given in G K Pal Textbook of Medical Physiology on pg. 554 which states as follows
" Actually, it is the resting membrane potential that automatically depolarizes to form the pacemaker potential. Thus in pacemaking tissues there is no resting membrane potential, rather the pacemaker potential is the restless membrane potential.
But isn't the resting membrane potential of pacemaker tissue also know as the pacemaker potential? Can you please explain mam?
It’s two different ways of saying same thing
🤗
😊
Mam u r teaching wrong there is no sodium in pacemaker tissue itz only potassium and calcium
Did you listen to the video
I have spoken about calcium only
Thank you mam
Most welcome 😊