The Ultimate Guide to Men's Hormones - TIER LIST (DHT is a trash hormone part VIII)
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- Опубликовано: 29 авг 2023
- Linked videos:
Team 3D Alpha tiered hormone video:
• The Ultimate Guide to ...
DHT trash hormone series:
• Why finasteride is saf...
• DHT is a trash hormone...
• DHT is a trash hormone
• DHT is a trash hormone...
• DHT is a trash hormone...
• DHT is a trash hormone...
• DHT is a trash hormone...
• DHT is a trash hormone...
Neurosteroid series:
• Finasteride and neuros...
• Why you shouldn’t worr...
• Finasteride is good fo...
• Does finasteride affec...
• Does finasteride cause...
Optimal dose of finasteride:
• What is the optimal do...
Why going bald will ruin your life:
• Why going bald can rui...
Finasteride in the young:
• Will using finasteride...
Finasteride and beard growth
• Will finasteride kill ...
5AR blockers and depression, anxiety:
• Finasteride does NOT c...
• Does finasteride cause...
DHT and muscles
• DHT is a trash hormone...
• Can exercise cause hai...
Finasteride and gyno
• Can finasteride or dut...
Will finasteride shrink your penis:
• Will finasteride reduc...
5ARIs and insulin resistance, diabetes
• Does finasteride for h... 5ARIs and Blood Pressure & Heart Disease
• DHT is a trash hormone...
Truth about dutasteride's side-effects
• The truth about dutast...
All the 5AR isoenzymes:
• Why finasteride is saf...
5ARIs and prostate cancer:
• Does finasteride cause...
Why going bald can kill you:
• Why going bald can kil...
Bludflow and hair loss
• What I've Learned and ...
• Why scalp massages do ...
• Blüdflow & Hair Growth...
Sources:
1. Imperato-McGinley J, Guerrero L, Gautier T, Peterson RE. Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism. Science. 1974;186(4170):1213-1215. doi:10.1126/science.186.4170.1213
2. Barud W, Palusiński R, Makaruk B, Hanzlik J. Dihydrotestosterone treatment in men with coronary artery disease. I. Influence on sex hormones, lipid profile, insulin resistance and fibrinogen. Ann Univ Mariae Curie Sklodowska Med. 2003;58(2):241-246.
3. Bortolato M, Frau R, Orrù M, et al. Antipsychotic-Like Properties of 5-α-Reductase Inhibitors. Neuropsychopharmacol. 2008;33(13):3146-3156. doi:10.1038/npp.2008.39
4. Andriole GL, Bostwick DG, Brawley OW, et al. Effect of Dutasteride on the Risk of Prostate Cancer. New England Journal of Medicine. 2010;362(13):1192-1202. doi:10.1056/NEJMoa0908127
5. Mysore V. Finasteride and sexual side effects. Indian Dermatol Online J. 2012;3(1):62-65. doi:10.4103/2229-5178.93496
6. Beggs LA, Yarrow JF, Conover CF, et al. Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone. Am J Physiol Endocrinol Metab. 2014;307(5):E456-461. doi:10.1152/ajpendo.00184.2014
7. Upreti R, Hughes KA, Livingstone DEW, et al. 5α-reductase type 1 modulates insulin sensitivity in men. J Clin Endocrinol Metab. 2014;99(8):E1397-1406. doi:10.1210/jc.2014-1395
8. Joyce KE, Biggs ML, Djoussé L, et al. Testosterone, Dihydrotestosterone, Sex Hormone-Binding Globulin, and Incident Diabetes Among Older Men: The Cardiovascular Health Study. J Clin Endocrinol Metab. 2016;102(1):33-39. doi:10.1210/jc.2016-2623
9. Swerdloff RS, Dudley RE, Page ST, Wang C, Salameh WA. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocrine Reviews. 2017;38(3):220-254. doi:10.1210/er.2016-1067
10. Da Silva MHA, Costa WS, Sampaio FJB, De Souza DB. The corpus cavernosum after treatment with dutasteride or finasteride: A histomorphometric study in a benign prostatic hyperplasia rodent model. Asian J Androl. 2018;20(5):505-510. doi:10.4103/aja.aja_28_18
11. Goodman PJ, Tangen CM, Darke AK, et al. Long-Term Effects of Finasteride on Prostate Cancer Mortality. New England Journal of Medicine. 2019;380(4):393-394. doi:10.1056/NEJMc1809961
12. Wei L, Lai ECC, Kao-Yang YH, Walker BR, MacDonald TM, Andrew R. Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study. BMJ. 2019;365:l1204. doi:10.1136/bmj.l1204
13. Chen X, Liu B, Li Y, et al. Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture. Frontiers in Pharmacology. 2020;10. Accessed August 29, 2023. www.frontiersin.org/articles/...
14. Round P, Das S, Wu TS, Wähälä K, Van Petegem F, Hammond GL. Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity. J Biol Chem. 2020;295(5):1202-1211. doi:10.1074/jbc.RA119.011051 
Хобби
I bust a nut every time I block the trash hormone DHT
Me too!
@b9g7 Yes you can 🤣
@b9g7DHT is a worthless hormone. Enjoy baldness baldy boy
@b9g7 People have kids whilst on Finasteride and Dutasteride you doofus 😂
Just added dutasteride to my regimen to bust even more nuts
DHT is a hormone your body forgets to stop producing after puberty. Finasteride is my once daily reminder
Father, you're literally my Kevin
Lmao 😂
Lmfao
Isn't it like 4am in Colorado right now? Kevin pulling an all-nighter to warn us about hormones, truly one of the RUclipsrs of all-time ❤️
Nah nah nah, this is just a man's sleep schedule after getting Armored Core 6. Seriously though, fortunate for his videos and time.
@HaggisDruid 😆 Armored core 6. Does Kevin have a gaming channel btw?
DHT=age hormone, necessary during puberty but horrible afterwards
💯
@Julius1997.
Don‘t believe him. It is necassary for many things, libido, sebaceous glands, brain health and many more
There must be so many things with our bodies that are good for a while but then we’d be better off with turned off
You should at least keep it low after puberty.
That's precisely where this guy lost all credibility to me. DHT actually lowers with age it doesn't increase. Calling it aging hormone is absurd.
I think it’s finally my time to post my Kevin “The” Mann praise comment. You were what pushed me to start finasteride and minoxidil last month. No side effects as far as I can tell. You are seriously doing everyone a service with these videos Kevin and I can tell how hard you work on them. I would not have started had it not been for your videos as I originally had a terrible preconception (and misconception) of finasteride from online fear mongers. NW1, no loss.
Appreciate that, choom! When I set out to cover hair loss I did so with the hopes that people would be able to tell me that the information I provided genuinely helped them. Seeing comments like this affirms that all of my efforts have been worthwhile.
Happy to have you here, homie.
@@haircafekevinbruv you are literally the gold standard of hair loss information on RUclips
@@haircafekevinSeriously bro! You're the man who leads the way through darkness!
He is deserving of many applauses and in general too, great channel
THE VIDEO WE ALL WERE WAITING FOR
I got to uni, and, as I look around, I realize just how many men are already going bald in their late teens and early 20s. To think that I can confidently know that I will never have to worry about going bald is something I am grateful for. I credit this channel for most of my core education on this topic.
Well you might not be so lucky. I've been on fin for a year and it's done nothing
@joshua.johnson
You may experience problems long term with this drug, its not worth it
@@George-nv1rii am on dutasteride twice a day. It works amazing
Haha for sure u are going to worry about balding in a few years
@@emilianomederos well I think he means he won't worry because he knows he can start finasteride
Great video man you are truly undefeated lol. So informative while being very entertaining!
I've missed you Kevin. Great to have you back.
FAST and GREAT INFO. At first I was annoyed by it but then I realized how much information he provides per minute. 99% youtbers dance around words saying nothing, half of the time saying "ehmmm, ohhhhh, soooo "etc. keep it up and thanks for the research
Thanks. With so much to cover, I could only deliver the highlights, otherwise the video would be 5 hours long. The guy made so many claims without any evidence.
Incredible video as always Kevin. I really enjoy your content almost regardless of what you're talking about. Your way with words and talking is just very nuanced and entertaining
Great video as always, man!
I'm not gonna lie, I never thought I'd live long enough to see a hormone tier list. What's next ? Organs' tier list ?
I long for a body part tier list.
Eyes and brain are SSS tier
how can you not love this man, the humor with the scientific evidence *chefs kiss*
Looking great kev!
Your channel is gold!
Yessss, I saw his video come up in my feed and was WAITING for you to clap back.
He puts out some okay content here and there but he’s definitely also a cholesterol simp and bashes plant based diets pretty often so I had a vested interest in the hopes you’d create this video hahaha
Nice video lore Kevin. "Just save it bro" is our mantra.
I would like to thank you KEVIN for your content you literally saved me from balding having my thick hair back = happy life , you are the GOAT
Kevin you the Messiah for the Hairloss community! You killed it with this response.
I legit burst out laughing at work when Kevin brought up Vegeta, Raditz and Nappa were spared for being Norwood IIIs and Norwood 7 respectively. Then of course the shot at Jason Blaha. This is why Kevin is the king, important information whilst being funny AF.
There’s a reason that everyone knows what testosterone is but practically no one has heard of dihydrotestosterone. Can you imagine someone saying “DHT filled action movie”?
The only people that know about DHT are doctors and people suffering from AGA. That’s how influential it is.
What does AGA stand for?
@@leonz5020Androgenetic Alopecia
@@leonz5020 Androgenic Alopecia
@@leonz5020 Or Androgenetic Alopecia
@@leonz5020
A
Gay
Albino
I watched team 3d alpha's video and immediately thought of you. I wanted so badly for you to make a video on that topic
Your wish is my command.
I'm a PFS sufferer from eating one lion mane's mushroom and drinking one glass of grapefruit juice as a dessert .
Suffered from PFS since then, got a micropenis and even turned into a woman. Now you should call me Caroline !
But how is your hair?
@WILDFIRE096 the truth is I'm on the dutasteride master race 0.5mg a day + topical minoxidil once a day and my hair are looking better than ever before, my health is good, my testosterone increased, i don't have dandruff anymore etc.... and DHT is a trash hormone.
@@exactly1176 good to hear! I hope your hair ages like a fine wine 😁
I looked at a bottle of finasteride and my dick fell off.
Man i need dutasteride so mich for my itchy scalp and etc, i am on fin already but duta may stop the itch, and i also have acne on my body, need to try duta if thats true
I knew this was coming thank you Kevin 🙏🏾
I've been taking fin since 1998. The only side effect that I've noticed is I look awesome. I think there might be some anti-aging too I'm 56 and I look 36 years old.
Yeah, Kevin also looks very young for his age
Does it increase your humility? Lol
What brand are you using?
@@ballislife9924how old is he?
@@David-mu3zs I think early to mid forties
The dragon ball analogies you were making had me legit dying of laughter haha. Another Chad Kevin moment.
Kevin, You’re literally my father
Kevin, Du bist buchstäblich mein Vater
كيڤن، انتَ حرفياً أبوية
I started losing my hair at puberty at 14 years old, wish I could have access to this information 16 years ago, would have saved me lot of ground and efforts, thanks Kevin 🔥 you're doing what a lot of people cannot
Thank you for enlightening me about DHT and finasteride, this feels like a hack in life
I almost started choking on my coffee when Kevin said that Team 3D guy had 100,000 more subscribers than he does. There are people that actually do research, can convey the facts so most people can understand it, are interesting, AND make art out of their thumbnails..and then some uninformed, biased individuals doing halfassed research can get way more subs. Sometimes life is just not fair.
That‘s 140k men who suffer a competitive disadvantage against men who keep their hair.
@@volos_olympus Yeah. I hate to see it. Hopefully they stumble upon this Haircafe video debunking him.
@@Mister_Cool here I AM tHANK GOD team 3d ALPHA is the reason i didn't start treatment at 18 and i have lost more hair since than its been 6 months luckily my hair loss is DUPA so my hairline isn't moving but man oh man how gratefull i am to discover this channel, Im decinding to start on 1mg daily or every other day or to start with DUtasteride at 0.5 daily
Team 3d Alpha is actually a very good channel and the guy is very informed, I recommend you to check it out. Maybe he's wrong about DHT but you can't judge an entire channel based on opinion about one subject
@@user-us4mc7ej3c idk I also stopped watching his channel sadly since I got bicep tendinitis copying what he said about certain exercises being m bout to nut category 💀 more like I'm about to overstress my tendons category instead but now I haven't trained in 8 months but I'ma rehab my bicep tendon soon, and instead I'm learning from Martin Rios the leon edwards guy 🤣
Im fan of both, thanks for your videos
Ive been watching both of your channels for a long time
Funnily enough, a guy finding BOTH of these channel is at his best. Haircafe might also be the biggest positive surprise other than T3dalpha a year ago, which is my case.
what a badass dht destroyer
Yeah Jreg, you really owned those DHT hormones
Stop following me around RUclips u federal agent
We can see that Kev was exhausted after this one ahah. Good work white wolf!
How are you doing fellow dutasteride master race brother ?
Everything is nova! I just stop alcohol as promised. I even try to be vegan (with the exception of dutasteride of course). Hair is still improving and my skincare is top tier! And you? Do you have a preemmmm week?
Hopped on fin due to Kevin and I can confirm that most people experience 0 side effects. I started with a prescribed dose of 1mg/day and I've been taking it for 3 months now, literally 0 side effects whatsoever.
Same I was so scared for nothing haha
Only sides I got was a long ass shedding phases and ball ache a week in for about a few minutes and never again. Now over a year later and my hair is so much thicker. And my hairline is growing back in when I added oral minoxidil.
How long did your shedding phase last? Taking fin + 3% topical minoxidil for a week now and noticed my bald spot getting worse 😰
Fin shedding can take up to 3-5 months from what I've read but it generally means it's doing it's work. For me seems to have stopped at about the 3 month mark.
blason jaha approves of DHT
The only one possibly saving that is the broken clock being right twice a day fact
Can you make a video showcasing your journey with pictures of before and after your treatment?
I recall watching a documentary on TV many years ago...before the internet blew up and therefore well before I became addicted to RUclips. The subject matter was following the progress of women who were about to commence a transitioning program/protocol towards sex-change surgery. This would require them to first go through months of psychological counselling, followed by months of hormone treatment, and then finally the surgery. Although I watched it a very long time ago, a couple of things made a big impression on me and stuck with me. The first thing was that prior to starting testosterone treatment, they did a simple physical test on the women which resembled a sort of shooting type of video game. This test was performed again at 3 months and then at 6 months. What it showed is that during the course of the testosterone treatment, the speed of their reflexes and their ability to "rapid-fire" improved markedly.The second thing I remember relates to the latter stages of the hormone treatment where not only was testosterone administered, but DHT was added into the "stack". One of the test subjects was interviewed and she made a point to remark upon the powerful subjective effects of DHT as it was raised to typical male levels in her body. She was saying things like "Whoa, DHT is some powerful stuff!...I had no idea I could feel like this". She went on to reference increases in Libido, increases in aggression, and increases in feelings of confidence and dominance. For some reason this stuck in my mind at the time even though I was a young guy, not losing my hair, and not having any clue about what DHT was and its link to hair loss. So, nowadays as I have joined the ranks of men who are battling hair loss, I have become more aware of DHT, and of course also become aware of Kevin's "DHT is a trash hormone" campaign. However, it seems to me that it is quite possible that DHT does play a role in "feeling masculine" and in manifesting male behavioural traits and attitudes. Perhaps there are 2 sides to this coin and some might argue that we''d be better off with less DHT in the world because there would be less conflict, war, tyranny, and sexual crime (not to mention more hair). But I can't help feeling that all these anecdotal stories of men feeling like they've "lost their edge" or of depressive-like effects is a totally reasonable and expected side-effect of nuking DHT. Is this hypothesis so ridiculous Kevin, and shouldn't you consider taking a more balanced view of the role that DHT plays in simply "feeling like a man"? Perhaps it doesn't work like this for you personally Kevin, but you don't know how it feels to exist in the mind and body of others, and on that basis perhaps a more cautious outlook would be wise.
Kevin, you are literally my haircafe
That DBZ analogy at 9:29 was fucking amazing lmao
😊
Kevin if im switching from fin to dut do i need to implement it slowly or can i just completely replace fin with it
50 seconds in and im already dying 😂😂
Kev is the only youtuber I trust
doing God's work Kevin 🥰🙏
Hey there Boss 😊, 3 months ago i started dutasteride after watching your videos and reading up on the research. Im in south korea and the doc said that here they just go straight to dusta as its a better version of fin. But they also prescribe fin if theres sides with dusta. No complaints here, i actually stopped using topical minoxodil cos its made my hair to dry and stiff and belive dusta should be sufficient. Anyways thanks for putting out the correct info so less people will be fearmongered , pfs 😂...
Hey there. I really appreciate the research you do on all your videos. I am vegan too for 13+ years. I am wondering if you can make a video about how DHT affects body hair (not scalp) since the older I get the more hair I am losing on my scalp but hair is also freaking growing everywhere where I didnt had before, like my ears, shoulders and back. I recently started taking finasteride but NO minoxidil (in case someone thinks that could be the cause). Thanks.
i have a question regarding topical minox. Everytime ii use it (i dont even use a lot), i get headaches and a light headed feeling that persists for a few hours. MY BP IS FINE AND I AM HELATHY. I started to resume it again and everyday for the past 5 days of using it, each time i get those same side effects. i was reading on reddit and several people seem to say that after 2 even 3 weeks, those headaches went away for them. What do you think i should do. Should i stick through or stop. My derm doc said some people are sensitive to that but he didnt say to stop or to psuh through. Maybe you have some experience with that. Thank you good sir
Kevin does dutestride cause weight gain i have been experincing some weight especially on face is that really cuz of dut ?or can i reduce it with diet although im excersing a lot i used fin for 9 months but shedding didnt stop then i started dut but i feel bloated should i go back to fin please reply
Maaaan you're so handsome with this hairstyle!
Hi Kevin, thanks for your service. I have been on finasteride 1 mg a day for a year, my hair density has increased. But I have started a bit of a shed ( not too severe ) right around the time I started taking Fin last year. I read about this and found that this is a documented phenomenon called synchronised shedding.
I couldn't make sense of the literature, but is it what I'm going through or the effects of finasteride have reduced?
God bless you Kevin
Hey Kev! I'm using Dutasteride 0.5mg EOD for hairloss and it's working really nice so far, but the thing is since it's every other day sometimes i forget if i took it the previous day or not. I wanted to know if it would be fine to use every monday, wednesday and friday and not use it on the weekends so that way i'm always consistent with it and don't have to worry if i forgot to took it, is it fine to use it this way since it has a long half life or would I be losing some of it's efficacy on the long run?
Dutasteride has a long half life. That is probably fine unless you have extremely severe hair loss.
Here for the info and also for the epic roasting
Damn this is like watching parents fight :/ saw the video and was hoping you'd respond to it. Didn't expect it to be this soon though haha. Still love Migan from team3dalpha, good dude with alot of positive content.
Same bro
I'm sure he's got some good content. I'm just hitting him on the DHT content.
Kevin is not only smart, he’s funny too. May god bless you and protect you from the slaphead curse.
Hey Kev, I'm shedding an extreme amount of small and miniaturized hair and barely any longer, thicker hair after 1.5 years of finasteride. That's a good sign for regrowth, right?
Might be a seasonal shed, but if it is predominantly miniaturized hair that is a good sign. The new hairs should be healthier.
Hey Kevin, I have a question. When applying minoxidil, do I have to rub it in, or can I just let it sit on my scalp like I usually do? I’m trying to maximize the results of the temples of my hairline.
I rub it in because it makes it less messy but so long as it touches the scalp it will work.
You’re father my Kevin literally
Great Video! Can you do a Video about Cosmerna?
Thank you and yes, I have. Right here.
ruclips.net/video/jQND9HyfdWo/видео.html
Love your videos. Seems like the most comprehensive and scientific out there on the topic.
Unfortunately, even with a very small dose (0.25mg 3x/week) of finasteride, I experience side effects. I was on it for around 4 months. Did halt my hair loss completely but I decided to stop since it hurt to pee and had sexual sides.
No sure if real side effects or placebo. Would be kind of incredible if a placebo was that potent. I noticed them as well with topical (actually more so) since I must have absorbed a very high dose.
Thank you!
Have you tried 0.1 MG. That is the smallest dose that still works. I made a video about it.
ruclips.net/video/15PHO1m6D-c/видео.html
Hadn’t seen that yet, will give it a try. Thank you!
@@moriorinvictus5569 any updates ?
Hey Kevin, Can You Create A New Video On Your Routine For Your Hair, Since The Last One Was A Few Years Ago?
Kev, are you using hair fibers in this video? Or any other form of scalp coverage?
I think I used a tiny bit of derm match. My hair was greasy here and when it's greasy it bunches up so I occasionally touch it up with derm match.
I laughed my ass off when you made the anime references 😂😂
‘Makes taking a piss is as hard as taking a shit’ 😂 comedy gold
Hey Kevin can u use 3 ml of minoxidil a day to get full scalp coverage?(5%)
Hey Kevin, is there any chance that starting finasteride early can have any affect on skeletal bone growth and development? I have seen a study associating dht with certain characteristics of bone.
No, I actually went over all of this in a video. Right here...
ruclips.net/video/6zdK_YdE1nM/видео.html
Hey Kevin, finding your channel was the best thing to ever happen to my hair. I appreciate everything you’ve done for the community. I started taking finasteride 1 mg a day with complete confidence that I wouldn’t get sides. After a few weeks, I had a significant decrease in libido and it was incredibly difficult to get an erection. This frustrated me a lot obviously. I’m 21 years old and in excellent shape. I’ve never had a problem with my sexual function ever; not even in the slightest. I wanted it to just be the Nocebo effect so bad, but it was hard to say it was considering how much confidence I have in the research I’ve done concerning finasteride. I stopped taking it for a week, and everything was pretty much back to normal. After a week without finasteride, I’ve been taking 0.5 mg every two days. It’s been about 2 weeks and everything is normal so far. I’m starting to feel confident that this dosage won’t give me side effects, but I am a bit worried that it won’t be enough DHT suppression. I have the strongest genetic bias towards androgenic alopecia out of anyone I’ve ever met. I know that 0.2 mg a day is the lowest dose with clinical efficacy, and I’m technically taking 0.25 mg a day, so I guess we’ll see. I might experiment with 0.5 daily if a few more weeks pass and I still have no sides.
I have a few questions:
Of course, my sexual sides were most likely due to an increase of estradiol. I’ve always had kinda high estrogen and maybe fin just put it over the tipping point. Is there any safe ways to suppress excess estradiol conversion without losing too much or causing other adverse side effects?
Also, in theory, for someone with an extreme genetic bias for androgenic alopecia that happens to be in the 1-2% that experience sides, what other options are there? I hate to be pessimistic, but my uncle took fin for over a decade and as far as I’m concerned he still lost ground (considering he’s completely bald). I also use topical minoxidil and I’ve had an SMP done for the illusion of more density (great results btw, I happen to live 20 minutes away from one of the best SMP artists in the US). Obviously, neither Minoxidil or an SMP will do much for the long term. I’m thinking that if all else fails, I can get a transplant and maintain ground with 0.2 mg fin or topical fin. What do you think? I’m not immediately assuming the worst, as that’s a nocebo effect on it’s own, but I am genuinely curious what options someone in that situation would have. For now, I’ll see what results I will get from 0.5 every 2 days and minoxidil. If nothing else, it’ll buy me some time to weigh out my options.
If you find the time to read and respond to this, I genuinely appreciate that a lot man. You’re an absolute juggernaut of truth and are single-handedly shifting the fear paradigm surrounding these treatments. Thank you for what you do man!
Thanks Witcher, glad to have you here.
Actually, 0.1 MG daily is the smallest dose of finasteride that still works. I talk about it here. ruclips.net/video/15PHO1m6D-c/видео.html
As I discuss in that video, finasteride isn't that dose dependent, 0.5 MG is only about an 8 percent difference for instance. DHT suppression has to meet a certain threshold to be effective and 0.2 MG still meets that threshold so I think you'll be fine at 0.5, especially since you're also using minoxidil.
A much better indicator of how effective your regimen will be is how early you started. Did you start at a Norwood 3 or 4? In that case you may want to consider a more aggressive routine like dutasteride or adding a topical androgen antagonist like pyrilutamide. But if you got into the game at around a Norwood 2 then it is likely it will be more effective. Basically, the longer you wait, the harder it is going to be to maintain. I talk about all of that here.
ruclips.net/video/LsF9MwIM_AM/видео.html
I think your routine is a good one. You did the right thing adjusting your dose as opposed to quitting when you didn't respond well to the standard dose. I wouldn't worry, and yes if you need a small FUE transplant in the future that is an option too, especially with treatments like verteporfin on the horizon.
If you absolutely cannot use 5AR inhibitors at any dosage, then topical anti androgens along with minoxidil are your best bet. At the very worst they'll buy you time until something better comes out like GT20029.
@@haircafekevin Thank you for the reply! I’ll check that video out now. As far as where I’m at on the Norwood scale, my hairline is relatively the same besides some regression on my temples. For the most part, I’m experiencing an even distribution of diffuse thinning specifically on the top of my head. Back and sides are thick as ever, but the top has lost just enough ground that it’s at times noticeable to other people. I’ve had my scalp tested for DHT and my dermatologist confirmed it was androgenic alopecia, despite not being the typical horseshoe pattern. It’s great news to hear that my routine is fine and isn’t worth worrying about. This is a longterm commitment, and I find it to be a fun experiment seeing what dose will work best for me. I genuinely have no loose ends, questions, or topics with mystery concerning finasteride or treatment for hair loss in general now. Thanks for restoring my confidence!
@@dewdroppy Happy to help, choom! Sounds like you got into the fight at a good time. I didn't get serious until I was a Norwood 3.5 so I definitely think you've got this.
Kevin, For the purposes of this video I know the topic is DHT. But at some point in the future would you be willing to talk about regular old prescription drugs known to cause hairloss and strategies to lessen or minimize the damage. Such drugs include Benzos, ace inhibitors, anti-depression drugs, and statins among others.. Thanks a million.
Yes, that is a good subject. I have discussed accutane's role in hair loss but I could probably cover other medications like anti-depressants and others.
Yo man your content is fucking awesome, im only 19 but im already learning about how to keep my hair forever.
You've got this.
Lmao the dragonball analogy killed me like Jiren
Kevin! Question for you, I started using minoxidil 15 months ago. However, eight weeks in, I stopped, since then I’ve been experiencing constant & noticeable diffuse thinning. Could it be that this shed will eventually stop, and I will return back to baseline? Or do you think I have androgenic Alopecia?
Thanks man, you are a blessing
I would assume you have androgenic alopecia and get back on treatment. Don't take any chances with your hair.
Hey Kevin,
college student here, I wrote you almost 3 months ago being on tight budget aspiring to regrow my hairline. You recommended me Minoxidil on top on finasteride for best results. As of now I am astonished by the results after blocking the trash hormone DHT. My hairline gets back. It is now like it was 2 years ago and new hair keeps growing. I see some little hair on temples and the hairline gets like 1-2 mm lower as it was. Balding spots begin to disappear. I experienced massive shedding first 2 months, now I don't see almost any hair falling out even after taking a shower. I am amazed. Looking forward to the regrowth to come.
I've been using finasteride 1 mg, Minoxidil once a day, Ketonosol here and there, Biotin and Multivitamin. I tried microneedling a few times but dropped it.
Thank you for your videos and your advice!
Wow! Sounds like you're a really good responder. Chances are things are going to get even better.
Congrats, choom! Now you get to enjoy your best years with a full head of hair and live your life to the fullest! Go have fun, you've earned it!
Which brands are you using?
@@meejmuas8686 Finasteride: I rely on Mephi.
Minoxidil: I've been using Regaine 5%, but I plan to switch to Alopexy once I finish the current package. Alopexy is a more cost-effective option for me.
Ketoconazole: I use Pilos shampoo.
the slander on balding vegeta,raditz and nappa got me ROLLING💀🤣🤣
Sup Kev,
I’ve been on Fin monotherapy for awhile, but I felt like I was losing ground (and my mind).
I upped my protocol to RU 2x a day and Dut .5 ED. Within a week I felt some Gyno coming on and immediately stopped and got my blood tested. My Estradiol was through the roof.
My question is, what was the cause, the Dut or RU? I’d still like to upgrade from Fin to Dut if RU was the culprit…
PS my experience on fin has been good, nothing to complain about
Probably the dutasteride. Mechanistically it seems more likely that the RU. However I've seen some people complain of gyno online from RU. Since RU development was abandoned, we don't know for sure the incidence of sides with it.
If you were only on Dut a week it wouldn't have had much chance to build up in your system and should be gone in a couple weeks. I'd probably pause a couple weeks and then probably just go back on fin for a while. You can always try adding dut later maybe once or twice a week and see what happens. I wouldn't add both dut and RU back in because if you feel the gyno coming back you won't know which one is causing it.
Slow, deliberate steps are best, and just changing one thing at a time makes it easier to figure out what's going on if you get sides.
Is there any way to tell if you’re at risk for getting headslapped by regular old testosterone? I remember you saying that it’s not common, but it can happen. Is worrying about test only applicable to people who are hypersensitive to AGA and started balding very early? Are there any indicators that you might be at risk, or are in the clear and only have to deal with DHT?
he made a video on it i think
He's mentioned test itself causing hair loss before but I don't think he's talked much about who that is applicable to. Do you know which vid?
@@zup9819 i dont remember which video but he said test doesn't cause hairloss because it doesn't fit the receptors that dht binds to and causes hairloss, could be wrong tho
@@seif9923 what you are saying about the receptors may be true. I’m not certain on the mechanism of action but I know it’s been said by Kevin and MPMD that test can have some direct influence on hair miniaturization, in much the same way DHT does.
I looked back, i actually think I may have misunderstood what was being said
Why are you always picking on this dude in the thumbnail 😂
No hate, it's just a meme.
Hey kevin! So it's been 7 months with 1.25 daily fin but i am still receiding. Im not looking for any regrowth at this point i just want to stabilize what i have at this very moment. Do you have something to say with dudes like me. Thank you
Topical minoxidil will help. You could also try dutasteride.
I would still say 7 months is too early but if after 10-12 months things are still getting worse then I'd try dutasteride. If you really want to stop hair loss dead in its tracks you can do 2.5 MG of dutasteride daily to suppress double the scalp DHT of finasteride.
hi kevin i just want to ask you im using finasteride then my doctor give me prioin capsules( swiss brand )
he told me is will promote hair growth and stronger hair is it good ?
the jason blaha joke out of nowhere i cant 🤣🤣🤣
Man you should invite him to a debate!
Moin
Im sry but i have a question regarding finasteride effects. Recently i read the study you used in ur videos the meta analysis on suicide and depression from france. The cited a study fro explaining the possible biology reasons that such might occur
Study called:
The connection of 5-alpha reductase inhibitors to the development of depression
I dont want to get into neurosteoids stuff since most lf it is basend on rats and stuff, but why in the first section highlight the also say
„Finasteride is an inhibitor of dopamine receptor 1-downstream signaling“
Ive seen you point out flaws in some study regarding transfering rident data in humans. Are those researchers simply not aware of that fact or are they ignorant?
The article is a review of studies on neurologic effects of finasteride, and the studies looking at dopamine are on rats. So they don't prove that humans have the same effects, because of the different effects of finasteride on the two 5AR isoenzymes, and the different doses used.
No the investigators are not being ignorant. There are people claiming that finasteride causes depression in humans, so these researchers are investigating possible mechanisms that would explain depression from finasteride. I don't think that it has been shown that finasteride causes depression, and I did a video on that, ruclips.net/video/1p5RD1Yd6jE/видео.html . But generally researchers do animal research first, and if they find anything in animals, they then do studies in humans. Since measuring neurosteroid levels in the brain of humans is not that easy to do, sometimes researchers will just publish the results of animal research, and usually they'll say that further human research is necessary to see if the same results hold in humans. Until that is done, any link between the effects in animals versus humans is just speculative.
@@haircafekevinso the effect on the dopamine receptor is also due to the 5 ar enzyme and not some other machanism?
Thks alot for the answr!
for muscles - more plate more dates ... for hair - haircafe
For the Phase III trial of Androgenetic alopecia(Long-term safety) in China, we finished first patient enrollment on 19 July. A total of 270 male and female patients will be enrolled and the treatment period is 52 weeks.
This is an email I got from Kintor, thoughts?
Hey Kevin!
About 4 months ago I switched from 1Mg Fin everyday to 1Mg MWF after taking it for 2 years at the daily dose. I really haven’t noticed anything different since switching over to MWF, yet I was curious if there a rough timeframe I should wait to see if this routine is working? I’m sure it varies a bunch from person to person but I didn’t know if there’s a basic rule of thumb on how long to wait and see if this regiment is still stabilizing the hair.
Thank you a bunch in advance! Screw DHT.
Yo!
For most people every day use VS EOD use likely won't make much of a difference.
Hair growth is cyclical so the minimum amount of time to expect to see any results is 3 months, but it can take as long as over a year for finasteride to really flex its muscles. A lot of it will be based on the conditions of your scalp when you begin treatment, such as how many hairs you have in the telogen phase which is randomized throughout the scalp since hair growth isn't uniform.
If you were on it for 2 years before and your hair is stabilized then I imagine your hair will continue to be stable even with every other day usage.
@@haircafekevin Thank you godfather 🙏🏼
@@cdebaun100 You bet!
Hey Kevin I was wondering if 19 is too early to start finasteride I was wondering what your stance would be?
No, it isn't. I made a video about this.
ruclips.net/video/6zdK_YdE1nM/видео.html
random question: Lets say i have hair shedding from minoxidil after stopping for one month, then go back on treatment. How long would it take for those hairs to return after starting again? assuming it's just causing general hair shed and not all from androgenic alopecia.
Probably about 3 months since that's how long the telogen phase lasts.
Kevin, why do you prefer pantostin instead of asking from your local pharmacy to add 17α-estradiol to your minoxidil solution ??? 🤔
My Father, you’re literally Kevin.
Hey I'm curious as to whether minoxidil loses efficacy over time and if stopping it after prolonged use can cause permanent follicle death?
No, it works indefinitely but you need to use it with a 5AR inhibitor for long term benefit.
You got me on fin now I got 5 friends on it too
Papa Choom's cluster bombs are a thing to behold.
I do hope at some point in the future probably not during my lifetime we'll have genetic engineering where we could go and have our bodies modified to reduce the DHT production after we're done with puberty.
Hello Ken. To be honest i follow team 3d alpha and i like how he presents his content, but his support on DHT always kept me on edge about some his information. He likes to overhype some theories that have not been proved. He also dislikes most of the medical community, mainly because he believes they dont like to treat causes but symptoms.
I have one question that is gaining some spotlight. Some reddit users (i know... lol) believe that DHT on the chest tissues may help prevent gyno and thats one of the main reason why Fin/Dut can cause it... What's your opinion on this?
There's a review article from 2022 looking at medical gyno treatments. There are 2 pretty old, small studies on using DHT topically with some benefit, but that's probably not enough data to say if it really works. Data that goes against low DHT as being the root cause of gyno is this study, www.fertstert.org/article/S0015-0282(13)03388-8/fulltext, that says that gyno is not seen in congenital 5AR type 2 deficient males. For 5AR blockers, I assume gyno is probably related to chaining estrogen levels. Maybe people who are born with 5AR deficiency compensate their enzyme levels or estrogen receptors in some way so that they don't end up getting gyno. But if gyno was just from lack of DHT, you'd think men born with 5AR deficiency would have a good chance of getting it.
Hey bro if you make your videos into separate topic sections that’d be cool
Yeah, I have been meaning to do this for a while.
hey how long would you suggest to use minoxidil for to determine if its effective for me?
At least 3 months, preferably 6.
Kevin what do you think would be superior in the Long run: taking 0,5 mg dutasteride every day vs taking 1,5 mg or 1 mg dutasteride 3 Times a week?
Probably about the same. Although dutasteride has a long half life so 1.5 might be better every other day. We don't have exact data on the amount of dot suppression but it is probably between 50 to 80 percent scalp DHT suppression.
Kevin im 24 what are your suggestions on ht with hairloss im on dutestride for 2months after a heavy shed its slowly stabilozing
Give the dutasteride at least another 8-10 months before deciding on a hair transplant. Beyond that, there are no issues with getting a hair transplant. Issues like donor availability will not be as big of an issue with treatments like verteporfin on the horizon.
@@haircafekevin kevin i was on fin for an year it fidnt work im planning on hairline Transplant i have full crown area