Lab-Grown "Mini-brains" Perform Non-Linear Computation, Eat Neurotransmitters, & Go To Space

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  • Опубликовано: 30 сен 2024
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    Human brain organoids ("mini-brains") are being grown in labs around the world. They're being fed neurotransmitters, competing with AI to solve non-linear equations, and going to space to study the effects of microgravity. This video reviews three preprints, preliminary reports of new scientific studies. (My AI voice caught a cold this week.)
    Support the channel: / ihmcurious
    Preprints:
    - Brain Organoid Computing for Artificial Intelligence (Cai et al.) www.biorxiv.or...
    - Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters (Park et al.) www.biorxiv.or...
    - Studies on the International Space Station to assess the effects of microgravity on iPSC-derived neural organoids (Marotta et al.) www.biorxiv.or...
    Videos:
    -SpaceX: CRS-19 Mission • CRS-19 Mission
    -NASA: What Launches to Space on SpaceX’s Next Cargo Mission [CRS-18] • What Launches to Space...
    -todo314: Henon attractor • Henon attractor
    Other Media:
    -Resting potential image: openstax.org/b...
    -GPU slide: 15418.courses.c...

Комментарии • 58

  • @GeoffryGifari
    @GeoffryGifari 10 месяцев назад +50

    Make them pass butter and I'll be impressed

    • @obelysk4209
      @obelysk4209 6 месяцев назад +3

      PR: what is my purpose?
      R: to pass the butter.
      PR: oh god!

  • @kaorudragneel8498
    @kaorudragneel8498 10 месяцев назад +14

    Love seeing my instructor become a successful RUclipsr with sponsorships. Keep up the great work. I always look forward to learning from your videos.

  • @Myblogband
    @Myblogband 10 месяцев назад +11

    If math wasn't torture enough, now the brains have to do it in a petri dish... sounds familiar, like school.

  • @degariuslozak2169
    @degariuslozak2169 10 месяцев назад +18

    This channel is so underrated♥

  • @WeAreTheDraiken
    @WeAreTheDraiken 10 месяцев назад +11

    Next phase of developing computers.
    Gonna wait till this is oeer reviewed to state my opinions , I'm really hoping that the increased maturity due to space travel is true. Cause my childhood self just wanna say Cosmic Rays or something.(even though I know the space shuttles are shielded.😅)

  • @LemonsRage
    @LemonsRage 9 месяцев назад +11

    And here we arer going full circle. Naturally developed brains develope devices running on anorganic matter just to discover that organic matter is just better. I am sure they will just add to this and discover a fully automated version of an organoid some day in the future. To make it easier they will encase it in a hard shell, give it limbs to interact and sensors to understand. Then after many iterations they will end up at humans

    • @esatacikgoz2016
      @esatacikgoz2016 5 месяцев назад +1

      thats never gonna happen because a human contains one thing that cannot be replicated with developing body parts from stem cells ii soul

    • @mgmchenry
      @mgmchenry 5 месяцев назад +2

      ​@@esatacikgoz2016fascinating. So when they make the humans with no souls and compare them to the ensouled humans, maybe they'll finally see where you're hiding those people things and make sure they get attached in the future

    • @TheRealityWarper08
      @TheRealityWarper08 4 месяца назад +4

      ​@@esatacikgoz2016
      So you decide who does and does not have a soul?

  • @marko.p.radojcic
    @marko.p.radojcic 4 месяца назад +3

    Fewer rounds of training and just the complexity of the system. Thank you for sharing, this is amazing

  • @poppysilver
    @poppysilver 10 месяцев назад +12

    this is horrifying

    • @Mr.BrainMeat
      @Mr.BrainMeat 10 месяцев назад +4

      I’m like this is terrible! Show me more 👀👀👀

    • @nulled7888
      @nulled7888 10 месяцев назад +3

      How is this horrifying lol

    • @blahblah367
      @blahblah367 10 месяцев назад

      ​​@@nulled7888 yeah, same. it's hurting my head trying to understand

    • @infiniteapex8762
      @infiniteapex8762 6 месяцев назад

      @@nulled7888exacly lol

    • @fraternitas5117
      @fraternitas5117 3 месяца назад

      I have a difficult time holding back vomit thinking over this

  • @FunkyJeff22
    @FunkyJeff22 10 месяцев назад +11

    Do these mini brains have everything a human brain does, like a hippocampus and occipital cortex, but miniature?

    • @ihmcurious
      @ihmcurious  10 месяцев назад +20

      Nope! They're relatively disorganized blobs of brain tissue. Check out this video for more of an introduction: ruclips.net/video/u6FGq7_t3Eo/видео.html

    • @unk4617
      @unk4617 10 месяцев назад

      ​@@ihmcuriousis there a scenario where we can grow these blobs with that level of organisation
      If so does that mean we'll ne stuck with the types of regions in the brain or will we be able to make a "brainoid" with regions for more specialised tasks ?

    • @giakolou2876
      @giakolou2876 10 месяцев назад

      @@ihmcuriousuhm hey, the discord link doesn’t work… u got a fresh one maybe?

    • @ihmcurious
      @ihmcurious  10 месяцев назад

      Refreshed

    • @ihmcurious
      @ihmcurious  10 месяцев назад +1

      Specialization and new brain regions never before imagined are possible

  • @sashakoshka
    @sashakoshka 3 месяца назад +1

    the big problem with replacing digital neural networks with biological ones is that digital ones can store their state once trained and be duplicated infinitely as long as you have enough hardware. biological networks must be trained individually. until brains can be copy pasted this approach will not be viable.

  • @ghostagent3552
    @ghostagent3552 10 месяцев назад +15

    hold on a minute... does this imply that we *could* potentially teach people math problems this way?
    If so, we literally just created the basis of installable knowledge

    • @slasheffecttech
      @slasheffecttech 10 месяцев назад +3

      matrix moment

    • @orbismworldbuilding8428
      @orbismworldbuilding8428 10 месяцев назад +1

      Looks like it

    • @TheLolzKnight
      @TheLolzKnight 10 месяцев назад +17

      No, probably not. Molecular geneticist here (Biologist). The way these organoids are taught to do problems is by having them attach to certain electrodes, which then feed them electrical pulses. The electrical response to these signals is then measured at another electrode, and when the neurons working together give us a response we like (the right answer) we reward them chemically, causing the neurons to plastically change connections so they produce the signals we like.
      The thing is your brain doesn't work that way. When we see a math problem, it passes from our eyes to our brain as visual information, then our brain decodes the meaning via the cooperation of millions of neurons. You don't have one nerve that carries all of the math problem as easy to read pulses for the organoid to attach to. It's spread through your whole brain. The same goes for the answer, the only time that ALL the information comes together again is when your brains starts trying to communicate it. Which is again a task done by thousands of neurons.
      On top of that, even if we could figure out how to attach it in one person, it would only work for one person. General brain structure is conserved across all humans. But the exact placement of neurons is not. Imagine two identical valleys that are settled twice be different people. You'd probably get similar cities, but the exact place each building and shop is put would probably be quite different
      On top of that there is the practical issue: doing brain surgery on yourself to avoid doing math homework is probably not worth it.

  • @pinguin00o73
    @pinguin00o73 6 месяцев назад +1

    Wow never knew the human vs computer processing battle is still raging on.

  • @xxxlatif
    @xxxlatif 7 дней назад

    Surely the human life expectancy will soon be 100+

  • @ihmcurious
    @ihmcurious  8 месяцев назад +1

    Hey, who's here for class? What class is it? Welcome, class!

  • @Cyclically
    @Cyclically 10 месяцев назад +2

    I swear to god that thumbnail is making me see things

  • @Bassnerd
    @Bassnerd 9 месяцев назад +1

    soon you’ll be able to enjoy a nice cup of coffee, plug into your brain, and enjoy the video game Scorn.

  • @professorstevepotter
    @professorstevepotter 3 месяца назад

    Great stuff!
    Cai's brain-o-ware was published in Nature Electronics: Article
    Published: 11 December 2023
    Brain organoid reservoir computing for artificial intelligence
    Hongwei Cai, Zheng Ao, Chunhui Tian, Zhuhao Wu, Hongcheng Liu, Jason Tchieu, Mingxia Gu, Ken Mackie & Feng Guo
    Nature Electronics volume 6, pages1032-1039 (2023)

  • @VikrantSingh-se2zb
    @VikrantSingh-se2zb 2 месяца назад

    From mind blowing, to brain numbing evolution in space time engineered control planes under the skin. Thank you.😊

  • @dankduck
    @dankduck 10 месяцев назад +2

    Hey watched your videos last year glad to find this channel again

  • @tommyjay7287
    @tommyjay7287 Месяц назад

    I know your talking hard science and have to be serious but space yeast, really?

  • @billburgess9100
    @billburgess9100 2 месяца назад

    What could happen if the mini-brain cells was harvested from the brain of a serial killer ?

  • @howrandy
    @howrandy 4 месяца назад

    how long to grow ??.. how long they will survive ??..

  • @scotchjones9048
    @scotchjones9048 2 месяца назад

    ah sweet , man made horrors within my comprehension

  • @Charlie-Em
    @Charlie-Em 10 месяцев назад +1

    This is pretty badass but I hope the bad guys don't get it

  • @jujuoof174
    @jujuoof174 4 месяца назад

    Very well-explained and interesting!

  • @lecrowpus.
    @lecrowpus. 10 месяцев назад +1

    ❤🎉🎉
    First

  • @ablazedguy
    @ablazedguy 5 месяцев назад

    Why doesn't Anheuser-Busch start with brewing beer on Earth before doing it in space? Shouldn't they first start with the easier process?

  • @isaacwellborn
    @isaacwellborn 2 месяца назад

    Spy Kids

  • @Monorat
    @Monorat 5 месяцев назад

    So have these guys grown big, and then make a bunch of AI robots too, and then have them fight and beat AI

  • @liteseve
    @liteseve 10 месяцев назад

    "[...] brew beer in space. Both admirable goals" 😂 I feel you

  • @Tracing0029
    @Tracing0029 5 месяцев назад

    As a computer engineer I want to go back and do brain related grad as well now 😂

  • @immortalityIMT
    @immortalityIMT 10 месяцев назад

    They are going to beat A.I. hands down!

  • @kindpotato
    @kindpotato 10 месяцев назад

    This research will be very cool until its scary.

  • @henrygingercat
    @henrygingercat 10 месяцев назад

    Brilliantly presented - thanks.

  • @SirChucklenutsTM
    @SirChucklenutsTM 10 месяцев назад

    Head cheee

  • @Chad-ie4wl
    @Chad-ie4wl 10 месяцев назад

    Well done

  • @contasfinalcontasfinal
    @contasfinalcontasfinal 10 месяцев назад

    cool 😎

  • @peterlin5145
    @peterlin5145 10 месяцев назад

    very exciting stuff!

  • @jitterdaoc9512
    @jitterdaoc9512 10 месяцев назад +2

    The only thing more next generation than 7:44 would be Bitcoin. Thank me later. Or fly a rocket to turn back time and send me some from the past.