I am ever more grateful that you continue to provide these lectures for free especially now that you have a paid membership offering . Because I live on Social Security and a budget that never gets me through the month I have no spare money to begin to afford to pay for this priceless information. Fasting is a necessity to make it until the next check arrives, hence my happy silver lining. Thank you for continuing to provide this education when I'm fully aware it is not free to you to provide it. God Bless you Dr. Bikman for your generosity. 🙏
Just stop eating and cook yourself in a sauna and you'll be healthy!!! lol. Stop following guru's that are pushing chronic stress as the way to health. Look up Ray Peat and bioenergetics instead. There, you'll learn how to actually support the body, not work against it, and thrive.
Love this we as humans need to look up to people like Ben who are trying to save us and not actors or athletes!! Thank you Ben for your amazing videos !!!
Happy New Year, Dr. Bikman & crew!🎉 wishing you all a very healthy and prosperous new year. My husband and my 33yo son have both chosen to join me to reclaim our health. Thank you for sharing this important information in scientific detail. You are a VALUED TREASURE.
Great info to include in a playlist I'm compiling for motivation to do a long fast after having slipped back to processed foods from a carnivore diet (near 3 years) for 5 weeks from a high stress family situation. Amazed how rapidly I became inflamed and how easily adipose tissue returned. I couldn't find my words and breathing became labored too. Back to carnivore and OMAD for one week (just sardines and beef) and inflammation is down, lungs don't feel restricted and brain function is returning.
I wish you strength and wellness. I, too, know that a sudden change in circumstances can impact routines and disrupt our more conscious and deliberate choices. Hope things are re-stabilising. ❤
What an interesting lecture! You have a gift for teaching in a very simple and clear, straightforward way, thank you so much for that, all your lectures are a treat for both the ears and the brain! Studying phytopharmacy and revisiting physiology these holidays, this channel has appeared at the right time, as the ECM is my favourite area and key, I believe, to true cure. Having spent ten years on vegan macrobiotics that has driven my diabetes away, I am now exploring ketogenic dietary principles. What attracted me to keto is the absence of sugar (have been living fully sugar-free for the last 20 years). Since i retained insulin control on unrefined-carbs-loaded diet, I'm trying to find the missing link :) Dr. Bikman, please keep on posting - you're one of the best contemporary lecturers, keep up the good work! All the best in the New 2025!!! ✨🪷
Thanks for this video - as a practicing physician 30 years removed from Biochem, it is nice to get these refreshers/updates! Would IGF/somatomedins be a potential future topic?
Well the first week of January I have been fasting... first a water fast transitioning to a dry fast for 5 days and now water and bone broth as I recover. Why would I do this? Autophagy. I so looked forward to the lecture.... thank you and Happy New Year Doc.
67 year old male on a keto diet have a 18 hour fasting window and 6 hr eating window daily. Have no MS symptoms after 23 years of suffering. Now have slow growing prostate cancer that urologist is monitoring. Do you think two 3 day fasts a month are better or one 6 or day fast? Do you get deeper autophagy by going longer than 3 days or is autophagy benefits the same over longer fasts.
Dr. Bikman! Love your info. I have a question: if autophagy is off when mTor is on and exercise activates mTor. Does this mean if you work out during fasting that there is not autophagy possible? Thank you!
I would love to hear your take on beta hydroxybutyrate as a powerful signalling molecule enabling epigenetics and gene expression. I am trying to explain why my vision has improved so greatly. My backstory is on my channel. Thank you love your work ❤️
@@pterakau Thanks for this. Exercise is my default 'cos a daily 20km bike ride is more enjoyable than depriving myself of food. Going back to OMAD next week 😊.
I did a 30 day waterfast and lost 25 pounds. I lifted weights during that time and found no decline in power. Would like to have some information on autophagy during long term fast
Long? 30 days is quite long. I think there is a sweet spot, a U shaped curve. Too little is not good nor is too much. The longest on record was more than 400 days. Muscle wasting is the down side of too much fasting but you sound like you have a handle on that, especially since you are monitoring your power. Keep an eye on that, Potassium, Mg. and so forth.
Efferocytosis vs autophagy. Which one do you like more? Intracellular recycling vs elimination of apoptotic bodies of aging, dying, and precancerous cells? In your opinion, with regards to foam cells, is this a function of an overload of macrophagic efferocytosis of oxidized LDL that then collect in damaged endothelium of artery vasculature(from HTN and inflammation). Also does low insulin result in increased efferocytosis? Intuitively, I suspect it does. If you think a talk on metabolism and efferocytosis is warranted, I'm all ears.
I thought that macrophages were free-form immune system entities that operated outside of the other cells. I also thought that their purpose was to eliminate and recycle damaged whole cells. Your discussion states that autophagy occurs within a cell. How would a macrophage enter a cell wall to clean up inside a cell? How would it get out when it was finished?
*Copied from another commenter... Autophagy Autophagy is a cellular process where your body cleans out damaged cells and regenerates new ones. It's like your body's way of recycling and repairing itself3. This process is essential for maintaining cellular health and can be triggered by various factors, including fasting, exercise, and calorie restriction. Benefits of Autophagy: Cellular repair: Helps remove damaged cells and promote the growth of new, healthy cells. Disease prevention: May reduce the risk of diseases like cancer, neurodegenerative disorders, and infections, Longevity: Some studies suggest that autophagy can contribute to a longer lifespan. Triggers for Autophagy: Fasting or intermittent fasting Exercise Calorie restriction Certain medications and therapies
Ketosis is a metabolic state where your body burns fat for energy instead of glucose. This happens when your carbohydrate intake is very low, prompting your liver to produce ketones from fats. These ketones then serve as an alternative energy source for your body and brain. Ketosis is often achieved through a ketogenic (keto) diet, which is high in fats, moderate in proteins, and very low in carbohydrates. Benefits of Ketosis: Weight loss: Many people use the keto diet for weight loss Increased energy: Some people report higher energy levels Improved mental clarity: Ketones can provide a steady energy source for the brain Potential health benefits: It may help manage conditions like type 2 diabetes and epilepsy Signs of Ketosis: Bad breath Weight loss Increased ketones in blood, urine, or breath Appetite suppression Temporary fatigue Digestive issues
Not "every now and then". Your house cleaning analogy is a good one. But just as a house should be cleaned routinely and regularly for maintenance, so should our bodies. Don't wait to recognize the "mess" or "stink".
I would love to join your community-have you thought about offering CME/CEU’s for us licensed people -it would definitely be worth my while to receive credits towards my license and be able to offset the fees.
I have read many books, I listened to many RUclips videos by many of the world's leading gurus and health experts but nothing came close to the 23 former doctor truths by lauren clark. I recommend everyone giving it a read.
Hi Prof., I’ve heard, Long term FaSTING is not HEALTHY for women especially over 60.. Is this True please? That Women need Protein 3x per day. ? Especially when doing exercise.. As Men’s and women’s Bodies are very DIFFERENT! Tnx Kindly! 🎉 Jen.
Ben, then next Jon Huntsman, Sr., Mitt Romney, Jeff Green, or Marriott !!! You're not a capitalist, brah - keep just teaching. Teachers are poor by design. I'll share with you my 89 yo mom's improvements if you contact me. Creatine is amazing as well as a dry fast daily.
Another excellent learning curve ! I really apppreciate the way Dr. Bikman delivers these complex processes so that the ‘average’ brain (mine!) can get a basic grasp of understanding? Thank you!🇦🇺🦘
![Felix "Unfair" | [Stray Kids : SKZ-PLAYER]](http://i.ytimg.com/vi/Oswujxm2Ag0/mqdefault.jpg)
I am ever more grateful that you continue to provide these lectures for free especially now that you have a paid membership offering . Because I live on Social Security and a budget that never gets me through the month I have no spare money to begin to afford to pay for this priceless information. Fasting is a necessity to make it until the next check arrives, hence my happy silver lining. Thank you for continuing to provide this education when I'm fully aware it is not free to you to provide it. God Bless you Dr. Bikman for your generosity. 🙏
It's propaganda sweetie.
Thanks Dr. Bikman. My doctor tells me how to stay sick and you tell me how to get well. Very much appreciated, you're actually helping people.
Just stop eating and cook yourself in a sauna and you'll be healthy!!! lol. Stop following guru's that are pushing chronic stress as the way to health. Look up Ray Peat and bioenergetics instead. There, you'll learn how to actually support the body, not work against it, and thrive.
I can never thank you enough for your time generosity to all of us who trying hard to get improve our metabolic state.
Love this we as humans need to look up to people like Ben who are trying to save us and not actors or athletes!! Thank you Ben for your amazing videos !!!
How the fuck are actors and athletes supposed to know? Lmao that's completely the wrong people to blame for the problem
Happy New Year, Dr. Bikman & crew!🎉 wishing you all a very healthy and prosperous new year. My husband and my 33yo son have both chosen to join me to reclaim our health.
Thank you for sharing this important information in scientific detail. You are a VALUED TREASURE.
Thank you. Happy new year to you too.
I so appreciate your lectures. Thank you for bringing science to us in short bits.
Great info to include in a playlist I'm compiling for motivation to do a long fast after having slipped back to processed foods from a carnivore diet (near 3 years) for 5 weeks from a high stress family situation. Amazed how rapidly I became inflamed and how easily adipose tissue returned. I couldn't find my words and breathing became labored too. Back to carnivore and OMAD for one week (just sardines and beef) and inflammation is down, lungs don't feel restricted and brain function is returning.
I wish you strength and wellness.
I, too, know that a sudden change in circumstances can impact routines and disrupt our more conscious and deliberate choices. Hope things are re-stabilising. ❤
What an interesting lecture! You have a gift for teaching in a very simple and clear, straightforward way, thank you so much for that, all your lectures are a treat for both the ears and the brain!
Studying phytopharmacy and revisiting physiology these holidays, this channel has appeared at the right time, as the ECM is my favourite area and key, I believe, to true cure.
Having spent ten years on vegan macrobiotics that has driven my diabetes away, I am now exploring ketogenic dietary principles. What attracted me to keto is the absence of sugar (have been living fully sugar-free for the last 20 years). Since i retained insulin control on unrefined-carbs-loaded diet, I'm trying to find the missing link :)
Dr. Bikman, please keep on posting - you're one of the best contemporary lecturers, keep up the good work!
All the best in the New 2025!!! ✨🪷
I was waiting for that classroom!!Dr. BIKMAN thank you so much for your work 🎉🎉🎉 I watch your lessons everyday!
Dear Dr.Bikman, thank you so much indeed for sharing helpful information.🙏🍀
Thanks for this video - as a practicing physician 30 years removed from Biochem, it is nice to get these refreshers/updates! Would IGF/somatomedins be a potential future topic?
What a great family science man .I am waiting for your book to receive in London 9-16 and thinking about the cook book.
Well the first week of January I have been fasting... first a water fast transitioning to a dry fast for 5 days and now water and bone broth as I recover. Why would I do this? Autophagy. I so looked forward to the lecture.... thank you and Happy New Year Doc.
Thank you. Keep updated. By the way I'm from Malaysia.
Thank you so much. You have taught me so much about the body and I just want to keep learning. Simply fascinating.
Thank you. This is the lesson I’ve been waiting for!
Thank you so much Dr Bikman. God bless you.
This is so motivating for the three-day post holiday fast I have started today, my first of two I aim for annually.
Thank you Dr. Bikman
Fasting, ketogenic diet help autophagy , exercising, sleep well and more.
Professor... Thank you for all of your great work and time you're spending to educate us!!
Happy New Year to you and your family! 🥩😉
Wonderfully made, humans are. Thanks for sharing!!
Thank you for these informative lessons.
Thanks
Thank you, Carol, for being so thoughtful. I appreciate it.
I decide to join Ben Bikman on his website. I have high hopes for the knowledge I will gain and the loved ones I can help.
EXCELLENT! Thank you.
Thanks prof!
Second! Ben is the best
Awesome Dr Ben💪🥰
67 year old male on a keto diet have a 18 hour fasting window and 6 hr eating window daily. Have no MS symptoms after 23 years of suffering. Now have slow growing prostate cancer that urologist is monitoring. Do you think two 3 day fasts a month are better or one 6 or day fast? Do you get deeper autophagy by going longer than 3 days or is autophagy benefits the same over longer fasts.
I would contact or watch work of professor Thomas Seifried...!!! It's his specialty...
MORE KNOWLEDGE, BETTER HEALTH-- a meme I shall use in my daily interactions.
What can you tell us about the effects of lectins in food on insulin resistance?
Dr. Bikman! Love your info. I have a question: if autophagy is off when mTor is on and exercise activates mTor. Does this mean if you work out during fasting that there is not autophagy possible? Thank you!
I just started carnivore after doing ketovore for about 6 months. I’m having one meal a day. What is the best way I can ensure or enhance autophagy?
I would love to hear your take on beta hydroxybutyrate as a powerful signalling molecule enabling epigenetics and gene expression. I am trying to explain why my vision has improved so greatly. My backstory is on my channel. Thank you love your work ❤️
Thank you! Do we know the effect of exercise on autophagy?
It increase!
@@pterakau Thanks for this. Exercise is my default 'cos a daily 20km bike ride is more enjoyable than depriving myself of food. Going back to OMAD next week 😊.
great info 😎
First🎉 thanks for your work
You’re the best Dr. Bickman 🥩🥩🥩🥩
🥩🥩🥩🥩🥩🥩🥩🥩🥩🥩🥩
Dr Bickman, thank you so much for all the knowledge that you share with us . But I did miss your tangent today 😊😊 have a beautiful 2025 🎉🎉
I did a 30 day waterfast and lost 25 pounds. I lifted weights during that time and found no decline in power. Would like to have some information on autophagy during long term fast
Long? 30 days is quite long. I think there is a sweet spot, a U shaped curve. Too little is not good nor is too much. The longest on record was more than 400 days. Muscle wasting is the down side of too much fasting but you sound like you have a handle on that, especially since you are monitoring your power. Keep an eye on that, Potassium, Mg. and so forth.
Very good👍
thank you!!!
Efferocytosis vs autophagy. Which one do you like more? Intracellular recycling vs elimination of apoptotic bodies of aging, dying, and precancerous cells?
In your opinion, with regards to foam cells, is this a function of an overload of macrophagic efferocytosis of oxidized LDL that then collect in damaged endothelium of artery vasculature(from HTN and inflammation).
Also does low insulin result in increased efferocytosis? Intuitively, I suspect it does.
If you think a talk on metabolism and efferocytosis is warranted, I'm all ears.
I thought that macrophages were free-form immune system entities that operated outside of the other cells.
I also thought that their purpose was to eliminate and recycle damaged whole cells.
Your discussion states that autophagy occurs within a cell.
How would a macrophage enter a cell wall to clean up inside a cell?
How would it get out when it was finished?
What about Time Restricted Eating (e.g One-Meal-A-Day) does this have similar benefits with respect to autophagy as a Keto diet does?
Ben, I was a little surprised that there was no mention of the effects/benefits of short-term fasting re: autophagy.
*Copied from another commenter...
Autophagy
Autophagy is a cellular process where your
body cleans out damaged cells and regenerates new ones. It's like your body's
way of recycling and repairing itself3. This process is essential for maintaining cellular health and can be triggered by various factors, including fasting, exercise, and
calorie restriction.
Benefits of Autophagy:
Cellular repair: Helps remove damaged cells and promote the growth of new, healthy cells.
Disease prevention: May reduce the risk of diseases like cancer, neurodegenerative
disorders, and infections,
Longevity: Some studies suggest that
autophagy can contribute to a longer lifespan.
Triggers for Autophagy:
Fasting or intermittent fasting
Exercise
Calorie restriction
Certain medications and therapies
Ketosis is a metabolic state where your body burns fat for energy instead of glucose. This happens when your carbohydrate intake is very low, prompting your liver to produce ketones from fats. These ketones then serve as an alternative energy source for your body and brain. Ketosis is often achieved through a ketogenic (keto) diet, which is high in fats, moderate in proteins, and very low in
carbohydrates.
Benefits of Ketosis:
Weight loss: Many people use the keto diet for weight loss
Increased energy: Some people report higher
energy levels
Improved mental clarity: Ketones can provide
a steady energy source for the brain
Potential health benefits: It may help manage conditions like type 2 diabetes and epilepsy
Signs of Ketosis:
Bad breath
Weight loss
Increased ketones in blood, urine, or breath
Appetite suppression
Temporary fatigue
Digestive issues
Cheers.
Every now and then you have to clean up the house, otherwise it becomes messy and stinking. Point taken 😉
Not "every now and then".
Your house cleaning analogy is a good one. But just as a house should be cleaned routinely and regularly for maintenance, so should our bodies. Don't wait to recognize the "mess" or "stink".
@@AzaleaBee I guess we can agree on "Just enough, not to much?"🙏
@@biodivers5294 That's a good way to phrase it. Some people tend to stay with the pendulum swung too far.
Great summary! Love it! 😊
How much of each one?
I would love to join your community-have you thought about offering CME/CEU’s for us licensed people -it would definitely be worth my while to receive credits towards my license and be able to offset the fees.
How many hours of low insulin or fasting do I need to get my body into autophagy?
Fwiw, all other youtube health creators say autophagy begins around 18 hours.
Please guide us on how can hypothyroidism be cured.
Fasting, walking, balanced meals, not over eating, stress management, weston a price... boom
Where’s the study?
Study of what?
@ he said it’s in the show notes but I don’t see it. The study about autophagy and fat cells.
I have read many books, I listened to many RUclips videos by many of the world's leading gurus and health experts but nothing came close to the 23 former doctor truths by lauren clark. I recommend everyone giving it a read.
Report this bot comment... Advertising some book
Hi Prof.,
I’ve heard, Long term FaSTING is not HEALTHY for women especially over 60..
Is this True please?
That Women need Protein 3x per day. ?
Especially when doing exercise..
As Men’s and women’s Bodies are very DIFFERENT!
Tnx Kindly! 🎉
Jen.
🎉🎉🎉❤❤❤❤
Danke
👍🏻
I'm going to pronounce it ah-tow-FAY-jik just to be contrary. 😜
❤
Ben, then next Jon Huntsman, Sr., Mitt Romney, Jeff Green, or Marriott !!! You're not a capitalist, brah - keep just teaching. Teachers are poor by design.
I'll share with you my 89 yo mom's improvements if you contact me. Creatine is amazing as well as a dry fast daily.
Do not understand your comment
Another excellent learning curve !
I really apppreciate the way Dr. Bikman delivers these complex processes so that the ‘average’ brain (mine!) can get a basic grasp of understanding? Thank you!🇦🇺🦘
Thanks Ben , excellent presentation 💪