Somatic Hypermutation And Affinity Maturation

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  • Опубликовано: 7 фев 2025

Комментарии • 42

  • @tmujir955
    @tmujir955 Год назад +1

    Dr. Richards you are an excellent teacher and I appreciate you sharing your talents with us!

  • @WeezyGR
    @WeezyGR 6 лет назад +28

    Words can't express how much this helped me, hope I'll do my best in tomorrow's immunology exam and this video right here just boosted my confidence a little more! Greetings from Greece!

    • @aaronbobby3819
      @aaronbobby3819 3 года назад

      pro tip : watch series at kaldroStream. Been using it for watching all kinds of movies during the lockdown.

    • @ericklevi9735
      @ericklevi9735 3 года назад

      @Aaron Bobby Yea, been watching on kaldrostream for since november myself :)

  • @arjavontalebzadeh4579
    @arjavontalebzadeh4579 4 года назад +7

    Thank you for sharing these videos with us. These have made me feel a lot more confident in my understanding this foundations block of my M1 year!

  • @kimberleymagic
    @kimberleymagic 5 лет назад +3

    Omg thank you for this! I finally understand the difference between the 2. You really saved me for my exam in 2 days

  • @rubabsyed2291
    @rubabsyed2291 Год назад

    I've watched so many videos on this topic, but yours was the one where it finally clicked! Thank you!

  • @drewetpa
    @drewetpa 4 года назад

    I'm just about to watch a presnetation on the isolation of neutralising antibodies from humans for SARS-COV-2. This helped me a lot to understand the Scripps paper. Thanks

  • @omarrasheed5469
    @omarrasheed5469 3 года назад

    Thank you Maureen! Your videos have been a great help preparing for exams

  • @SharonDeChenne
    @SharonDeChenne 2 года назад

    These explanations are very clear. Thanks!

  • @izumi1902
    @izumi1902 3 года назад

    Found you right in time , u saved me thank you soo muuch ❤❤

  • @komalkaren7019
    @komalkaren7019 4 года назад

    Thank you for such a great explanation. It helped me a lot.

  • @myprettygirl91
    @myprettygirl91 3 года назад

    amazing explanation!

  • @keshvichauhan6804
    @keshvichauhan6804 6 лет назад +1

    nice video

  • @ismatkaakar7535
    @ismatkaakar7535 7 лет назад +3

    Well explained, thanks!

  • @britling9101
    @britling9101 4 года назад

    Thank u so much for the clear explanation !!

  • @arkhamyt6052
    @arkhamyt6052 5 лет назад

    very nice explanation !!!

  • @asmita4062
    @asmita4062 6 лет назад +1

    Thanks a lot! Well explained :)

  • @yasminfouad3703
    @yasminfouad3703 7 лет назад +1

    Thank you! Very helpful video for studying for exams!

  • @mitchiecenon543
    @mitchiecenon543 7 лет назад +2

    Vary helpful :) Thank you

  • @zainabalradi2306
    @zainabalradi2306 7 лет назад +2

    You rock sisterrrrrr

  • @drpepper7801
    @drpepper7801 2 года назад

    Thank you luv

  • @FuzzyKittens007
    @FuzzyKittens007 3 года назад

    thanks!

  • @prepstar2.0
    @prepstar2.0 6 лет назад

    Nicely explained. Can you tell why the rate of mutation in variable region genes in quite higher than spontaneous mutation?

  • @keerthykrishnan2162
    @keerthykrishnan2162 5 лет назад +1

    Thanks

  • @ahmedsami8031
    @ahmedsami8031 6 лет назад

    amazing !

  • @techheaven007
    @techheaven007 7 лет назад +2

    thanks a lot.. :)

  • @linahkhaledalshwesh4721
    @linahkhaledalshwesh4721 6 лет назад

    brilliant !!

  • @paulchang8743
    @paulchang8743 4 года назад +1

    how can the activated B cell sense the binding affinity of antibody after the antibody is released? I just wonder...

    • @karankalani4211
      @karankalani4211 4 года назад

      Paul Chang
      It’s not just released antibodies. After shm, the B cells express their newer modified versions of antibodies on the surface. Just like B cell selection in the marrow, the better version is selected after checking which cell binds the antigen the strongest.

    • @muntahafazal237
      @muntahafazal237 4 года назад

      @@karankalani4211 nice question and good answer.

  • @05.abiramiindhu77
    @05.abiramiindhu77 4 года назад

    Thank you ❤️

  • @mohannedjamal9471
    @mohannedjamal9471 4 года назад

    thank you

  • @angelastuff107
    @angelastuff107 6 лет назад

    What gives the plasma cells feedback that it is indeed their Antibodies have greater affinity to the antigen and not some other neighboring plasma cell's (which makes antibodies with low affinity, for example) ?

    • @mourilshah2054
      @mourilshah2054 5 лет назад +1

      Antibodies with low affinity are usually cleared out

  • @em3027
    @em3027 4 года назад

    by activating the b cell you mean when it bibds to an antigen?

  • @shruthikarthikeyan1227
    @shruthikarthikeyan1227 4 года назад

    ❤️

  • @zaintariq2467
    @zaintariq2467 6 лет назад

    wonderful explanation! thanks