The Schwann Cell and Action Potential

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  • Опубликовано: 31 дек 2024

Комментарии • 139

  • @rajunaidu7751
    @rajunaidu7751 12 лет назад +6

    Amazing,better than a dozen textbooks combined.
    -clear and concise.

  • @PetarAngelov91
    @PetarAngelov91 10 лет назад +35

    I have Encephalomyelitis, i had destroyed myelin in my brain and in my spinal cord too i got sick last year on 13 February 2013 and i couldn't walk for 2 months after that. Also i had and still having troubles urinating, that's all keeping me away from my social life. I think i saw this video an year ago, but i forgot about it, THANK YOU SO MUCH for this video, now i can play it over and over again to visualize my axons healthy!!! :)

    • @srbijapodlupom9907
      @srbijapodlupom9907 5 лет назад +1

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    • @thispresentmoment7797
      @thispresentmoment7797 3 года назад +3

      How's it coming along? I hear nothing but good stuff about powerful symbolic visualization.

    • @PetarAngelov91
      @PetarAngelov91 3 года назад +4

      @@thispresentmoment7797 It's all good now, im completely healed, but it took me some years to recover ;) Never give up, never back down!

    • @thispresentmoment7797
      @thispresentmoment7797 3 года назад +2

      @@PetarAngelov91 YAAAAY😁😁😁.is it normal to recover from that tho? I wonder if the mental stuff actually worked even if the positive attitude was all that helped. So glad to hear you are all good now stranger.

    • @PetarAngelov91
      @PetarAngelov91 3 года назад +1

      @@thispresentmoment7797 thank you, mate, wish you all the best too, be abundant, be loved, be healthy and be wealthy 🤑🤗🧡

  • @ber1311
    @ber1311 15 лет назад +1

    This video gives me a clearer idea on the action potential across a myelinated neuron. Thanks. It helps me in my studies.

  • @eliaebast
    @eliaebast 11 лет назад +1

    simply amazing how the saltatory propagation is illustrated.

  • @nissedeprimerad7897
    @nissedeprimerad7897 10 лет назад +17

    Na+ is not really transported along the axon via diffusion, it is transported into the axon via diffusion, big difference.
    Please understand the following: diffusion is a very slow force and is only responsible for the generation of an action potential, not the conduction of the action potential or current itself.
    Inside the axon the impulse is actually conducted by electrostatic repulsion of positively charged ions that are concentrated very closely to the cellular membrane, K+ mostly. It works like domino, a Na+ (that enters the voltage gated Na+-channel) "hits" a K+ that "hits" another K+ and so on, all the way along the axon.
    The difference between myelinated axons and unmyelinated axons, is that unmyelinated axons are poorly isolated. The current leaks out from the axon and dies out unless its constantly replenished by new action potential generated by diffusion of Na+ into the axon via voltage gated Na+-channels. It's that easy.

    • @Robodude212
      @Robodude212 7 лет назад

      But aren't new action potentials always generated, so they are replenished? Generating new action potentials would speed up the net movement of ions, wouldn't it? Internodal spaces, on the other hand, cannot have the ion channels, so it is impossible to generate new action potentials. Doesn't this imply that Myelin sheaths would decrease speed, not increase?

    • @CrazyGamer-xi8rf
      @CrazyGamer-xi8rf 6 лет назад

      Couldn't have said it better myself

  • @Shes.A.Sagittarius
    @Shes.A.Sagittarius 13 лет назад

    WOOOOOOOOOOOOOW!!. it took my book one whole chapter to explain this simple little process.

  • @idolgin776
    @idolgin776 14 лет назад +1

    Nice video. I like the animations that illustrate the most important concepts and are not too flashy.

  • @tomnjerry12321
    @tomnjerry12321 14 лет назад

    The best video I've seen so far!Even better than my biology teacher!!

  • @mexiluvsw
    @mexiluvsw 11 лет назад

    my professor in my human anatomy and phisiology class is a grumpy old man! he is a former officer in the army and let me tell you it shows the way he teaches his class!!

  • @jordo62
    @jordo62 12 лет назад

    It isn't the diffusion of Na+ ions down the axon that is fast, it's the electrical charge from each of these ions that is conducted between the nodes of Ranvier that travels very quickly. In unmyelinated axons, the slower propagation of the signal is due to the increased number of ion channels (per unit of distance) that must open and close to maintain the action potential.

  • @PuraVid4
    @PuraVid4 13 лет назад

    @pirateXhunterXzoro The myelin sheath does not allow ions to exit/enter the axon. In a non myelinated axon, depolarization occurs at every step and the speed of the action potential down the axon is slow. In a myelinated axon, the only depolarization occurs at the nodes of ranvier and then the action potential is free to move down the axon until the next node of ranvier.

  • @amandacupuncture
    @amandacupuncture 14 лет назад +2

    Please make more of these! Very helpful!

  • @Reminiscable
    @Reminiscable 15 лет назад +2

    Watching this was more fun than playing videogames! I hope that my axons stay myelinated forever!

  • @DisturbedChildren519
    @DisturbedChildren519 12 лет назад

    You're basically correct until the very end. The refractory period only comes into play when the sodium ions diffuse in the opposite direction. If you notice in the video, when the sodium ions pour in, they move both left and right but the message is sent to the right. The reason the potential doesn't occur to the left is because of the refractory period. For a good explanation of the rest, look at Danelawz explanation.

  • @alisoncheung8061
    @alisoncheung8061 11 лет назад +1

    thanks for this animation, it furthers consolidate the info illustrate in the textbook.
    And I have a question, why there's node of Ranvier? I mean as long as the myelin sheath can speed up the signal transmitting, then why shouldn't the Schwann cells develop a longer length and cover the whole axon, so that the signal can transfer from the hillock straight to the end of axon?

  • @Drivenbymoney84
    @Drivenbymoney84 11 лет назад

    best neuron video so far on youtube

  • @PuraVid4
    @PuraVid4 13 лет назад

    @verosun12 Theoretically yes but there would need to be a Schwann Cell large enough to cover the length of the axon. The Nodes of Ranvier are actually the junction between two Schwann Cells (myelin).

  • @PuraVid4
    @PuraVid4 13 лет назад

    @pirateXhunterXzoro Think of it like a train. The unmyelinated axon has 20 stations on its route and at every station it must stop and unload/load passengers. This slows down the total time the train is moving towards its destination.
    The myelinated axon is a train with fewer stops. It only has to stop at a smaller number of stations (nodes of ranvier). This allows the the train to get to its destination faster.

  • @sotabel
    @sotabel 14 лет назад

    Very good video! (:
    Congratulations for the animation and the script, you made me understand finally what is the treshold. (:

  • @omieg89
    @omieg89 12 лет назад

    I think myelinated axons help nerve signals move faster because there are less channels to open up. The internodes help move the Na+ ions move down the axon faster. When they get to the next node of ranvier, the proper gates open up to trigger another action potential. In an unmyelinated axon, there are more channels that need to open up in order to move the signal along. It is slower b/c I believe you have to wait for the refractory period of each channel to be done.

  • @upahe3
    @upahe3 14 лет назад

    this is great for students of ALL levels

  • @lebonillab
    @lebonillab 15 лет назад

    Really cool!!!... this is really awesome and looks so professional.

  • @myusikah
    @myusikah 10 лет назад +3

    I want to point out that the open Na+ ion channels do not depolarize the neuron to -60. -60 is the voltage of the inside of the neuron at rest. Also, depolarization means to make less negative. Threshold is reached when the neuron's cytoplasm is depolarized to -55 to -50. The full depolarization of the neuron when the action potential reaches its peak is +50.

  • @thehandyart
    @thehandyart 4 года назад +1

    Amazing

  • @antarris
    @antarris 11 лет назад

    Is there a way through an enzyme, vitamin, food etc to activate the Schwann cells to start rebuilding the myelin sheaths that have been destroyed by an autoimmune disease?
    Thanks for an answer :)

  • @LC212689
    @LC212689 15 лет назад

    Thank you for this video! It is very clear, and helped me a lot in my understanding of saltatory conduction!

  • @aznnaruto777
    @aznnaruto777 13 лет назад

    I understand the train example above, but can someone explain in further detail? Like does the action potential start and end (resting) at each node and start again in the myelinated axon or does the influx of sodium in the axon keep the action potential from reaching resting state thus causing it to continually travel until it reaches the synapse? Or am I completely wrong?

  • @DeadHelena
    @DeadHelena 13 лет назад

    I don't think the Na diffuse in, its more like rush in by flux due to the electrical potential created from the K channels. Diffusion is much to slow to cause a signal to be passes quickly.

  • @rishabhkumar4861
    @rishabhkumar4861 3 года назад

    Superb presentation 😍
    Helped alot

  • @Madzor
    @Madzor 8 лет назад +5

    Nice job there! Oh and a great day to everyone reading this! :)

  • @___Han___
    @___Han___ 9 лет назад

    Elegant , simple and enjoyable

  • @TheOfficialReThink
    @TheOfficialReThink 9 лет назад +4

    Very helpful, thank you. Great music too, really enjoyed it. :)

  • @SanjeetaSharmaPokharel
    @SanjeetaSharmaPokharel 13 лет назад

    Thanks for explaining....the Action potential

  • @jdcatch
    @jdcatch 15 лет назад

    Excellent overview. Thanks!

  • @FearTheCalm
    @FearTheCalm 14 лет назад

    Can someone tell me why exactly it increases speed? Why does the action potential jump to the nodes of Ranvier? I know the Oligodendrocytes/Schwaan Cells act as a insulator, but that's about it...why doesn't the insulating material stop the electrical conductance? Is it maybe the sodium rushes to where channels are concentrated in the nodes of ranvier? =(???

  • @MrBleecker
    @MrBleecker 9 лет назад

    Awesome summary. Excellent work

  • @Muuip
    @Muuip 12 лет назад

    Great visualisation and explanation, Thank you!

  • @verosun12
    @verosun12 13 лет назад

    @PuraVid4 if the whole axon was covered in myelin would it travel faster since theres no stops?

  • @thehandyart
    @thehandyart 4 года назад +1

    Great information

  • @StumptownHomestead
    @StumptownHomestead 14 лет назад

    @plmqas Actually I believe she said that myelin was *thickest* in adolescence, which is why teenagers have such quick responses.

  • @konstantinozer6459
    @konstantinozer6459 7 лет назад +2

    thank you so much this video is so good for ranvier node..

  • @pirateXhunterXzoro
    @pirateXhunterXzoro 14 лет назад

    I'm so confused at 3:55 - 4:20. Can someone explain in simple terms why myelinated axons are faster than unmyelinated?

  • @thispresentmoment7797
    @thispresentmoment7797 3 года назад

    What does she mean by the inside of the cell reaching -60? Is that the charge or temperature?

  • @92-riyakumari52
    @92-riyakumari52 8 месяцев назад

    why myelin sheath does not covered the entire neuron ?
    Why there is gap Between Two myelin sheath ?

  • @Oxcilic
    @Oxcilic 11 лет назад

    So the Na gates open, Na floods in because of the voltage difference. Then it becomes +30 inside. If it's +30, why doesn't it rush out again? & if it is more positive on the inside after the Na gate opens, does this push the other positive ions onward, then the K gates open and positive ions flood outward, then that pushes positive Na onward, then that opens the next Na gate and it floods into the cell further down? If so why doesn't it just go in circles between 2 gates?

  • @TheDaveTit
    @TheDaveTit 12 лет назад

    Makes so much sense now!! Thanks.

  • @doejohn7445
    @doejohn7445 11 лет назад

    I heard of something about changing electric potentials... does that have something to do with myelin?

  • @dyepribudoy
    @dyepribudoy 14 лет назад

    the rushing in and out of Na+ and K+ is not quite clear here.

  • @ranechan
    @ranechan 14 лет назад

    Can someone please tell me the name of the song playing? or who it's written by?

  • @abdotahawey5343
    @abdotahawey5343 4 года назад

    Thank you💙💙

  • @magicallypossible
    @magicallypossible 14 лет назад

    this is really amazing!! i like the light background music as well :)

  • @vikasbr94
    @vikasbr94 13 лет назад

    awesome video

  • @PuraVid4
    @PuraVid4 13 лет назад

    @chrissline77 Thanks I'm glad a post I made a while ago was able to help someone out :)

  • @lindybindyify
    @lindybindyify 13 лет назад

    Best video out there! Thanks a milion! :)

  • @pillsburydourboy
    @pillsburydourboy 14 лет назад

    "axoplasm" is incorrectly captioned as "ectoplasm."

  • @WayneP2010
    @WayneP2010 13 лет назад

    Wonderful video! Thank you!

  • @srikanthnithyanandammd
    @srikanthnithyanandammd 11 лет назад

    Because node of ranvier is the only place where the ion channels are

  • @benjitarius
    @benjitarius 14 лет назад

    great video!

  • @nabeelkhan4648
    @nabeelkhan4648 9 лет назад

    awesome video got alot of things to learn

  • @smiley235
    @smiley235 12 лет назад

    Those Sodium symbols pouring out remind me of scrolling combat text.

  • @TheHappyTissues
    @TheHappyTissues 14 лет назад

    Very Helpful....i know ima ace my Physiology quiz tomorrow

  • @ZagiEscobar
    @ZagiEscobar 14 лет назад

    2:15 Does anyone know what the stimulus is?

  • @fighter4411
    @fighter4411 2 года назад

    What software was used to make this animation?

  • @johanbowling
    @johanbowling 14 лет назад

    cheers for that much better than my bio teacher!!

  • @Oxcilic
    @Oxcilic 11 лет назад

    Is the myelin sheath made up of Schwann cells or oligodendrocytes? Or both? How so?
    I'm confoozed!

    • @GIGHD
      @GIGHD 6 лет назад

      Oligodendrocytes are the glial cells present in the CNS, whereas Schwann cells are present in the PNS.

  • @Shiningstar104
    @Shiningstar104 7 лет назад

    Great Video , Thanks much

  • @bruswan
    @bruswan 15 лет назад

    You have to love it

  • @gamalmohamedashraf2746
    @gamalmohamedashraf2746 8 лет назад

    Great and very helpful job thanks alot.

  • @Vlaglz95
    @Vlaglz95 13 лет назад

    Awesome video I agree with Reminiscable this is better than be distracted by some video games : D!!!

  • @محمدمهدیپور-ل2غ
    @محمدمهدیپور-ل2غ 7 лет назад

    This is great.Thanks

  • @Caramelstick22
    @Caramelstick22 14 лет назад

    Very Helpful.Thank you!

  • @mehrshadpiano
    @mehrshadpiano 15 лет назад

    wow , it was very useful , thanks a lot . everything was s good , voice and animation .

  • @charlesbioful
    @charlesbioful 13 лет назад

    best explanation of the neuron of i've ever seen in my life. Narration skillz need a little bit of work though

  • @omieg89
    @omieg89 12 лет назад

    That's how I understand it. It is probably wrong and I would love to have someone correct me.

  • @hundreddollarbiller
    @hundreddollarbiller 12 лет назад

    Its a grade saver for me thank you so much.

  • @youlosez
    @youlosez 15 лет назад

    good info thanks

  • @أحمدالجولاني-ز8ج
    @أحمدالجولاني-ز8ج 5 лет назад

    *انا طالب في الشهادة الثانوية العامة*
    (بكالوريا)
    في syria
    وأريد أن أعرف كيف يتشكل غمد النخاعين؟
    ولم أجد الشرح المناسب!

  • @kaykentucky
    @kaykentucky 15 лет назад

    thanks for uploading on youtube =D helped A LOT!! lol i wish my lectures are conducted on youtube.

  • @thatswhatcindysaid
    @thatswhatcindysaid 13 лет назад

    Thanks!

  • @moonstarsunlee
    @moonstarsunlee 12 лет назад

    Helped a lot! Thank you

  • @paulafrengul9761
    @paulafrengul9761 10 лет назад

    Thank you!

  • @Thenebraskahanger
    @Thenebraskahanger 13 лет назад

    awesome

  • @mariemmohamed7161
    @mariemmohamed7161 12 лет назад

    thank you

  • @aapho
    @aapho 14 лет назад

    VERY usefull. it helped me alot, thanx.

  • @Nijaman24
    @Nijaman24 13 лет назад

    Thanks

  • @jnice61
    @jnice61 13 лет назад

    very helpful

  • @drnayanatara
    @drnayanatara 11 лет назад

    good one

  • @HadeerOs
    @HadeerOs 12 лет назад

    Amazing one....Thanks a lot:)

  • @Snyblind
    @Snyblind 15 лет назад

    Thank you. Helped a lot:)

  • @Hgryhffd
    @Hgryhffd 10 лет назад

    I love uuu thank u for alll your videos

  • @samvanzeeland
    @samvanzeeland 13 лет назад

    thanks a bucketlaod lady!

  • @JustAnotherTom
    @JustAnotherTom Год назад

    I thought the narrator was "Myelin Shopper"

  • @nadaa8892
    @nadaa8892 12 лет назад

    Thank you :)

  • @karamipayam
    @karamipayam 14 лет назад

    go CAVALIERS. VIVA Johnson County Community College :* I'll miss you even though I love KU.

  • @georgemurphy962
    @georgemurphy962 8 лет назад

    You probably already understand this. I thought it fascinating

  • @92asina
    @92asina 13 лет назад

    this was helpful

  • @realivame
    @realivame 12 лет назад

    thank's :D great animation

  • @StumptownHomestead
    @StumptownHomestead 15 лет назад

    Ha! Nothing so lofty. I actually made the score by looping some tracks in Garage Band. :-)

  • @RaiOne1
    @RaiOne1 13 лет назад

    bst video about action potential

  • @hello75986
    @hello75986 11 лет назад

    Good vid.