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Todas bien.
What if the volume of distribution is not given? What would be the appropriate step to do?
Good question. In such case we maybe have information about half-life and clearance. Then Vd can be calculated from half-life equation: Vd = 0.7*t/Cl, where t is half-life and Cl is clearance.
@@glebovlesha Dr. Hliebov, can we also use the formula (Vd= dosage\plasma concentration) to find the volume of distribution?
Todas bien.
What if the volume of distribution is not given? What would be the appropriate step to do?
Good question. In such case we maybe have information about half-life and clearance. Then Vd can be calculated from half-life equation: Vd = 0.7*t/Cl, where t is half-life and Cl is clearance.
@@glebovlesha Dr. Hliebov, can we also use the formula (Vd= dosage\plasma concentration) to find the volume of distribution?