I started on 500mg of niacin last Friday and whoah, DO NOT DO THAT, FRIENDS! I ordered some 50mg pills and have been on them the past few days. I honestly am feeling better. My brain is working again, my body temperature is starting to regulate a bit better, tinnitus is quieting and my breathing starting to almost feel normal. Thank you so much for these videos. You’ve helped so many people!
I started with 1x 250mg Niacin capsules once a day and upped to 500mg after 1 week (taken after lunch), controlling the flush comfortably with 1x aspirin taken before lunch. Should I reduce the dose better again or keep it that way, as it's bearable? I'm 2 weeks at it and there is a slight improvement in energy, although nothing dramatic.
@@frankttom4990 I first had symptoms back in the middle of March but wasn’t able to get tested until three weeks later and the Covid test was negative. Also tested negative for antibodies. But I’ve had breathing issues, tachycardia and palpitations, fatigue, hot skin which leads to feeling cold, intolerance to exercise and direct sunlight, tinnitus off and on but more pronounced since October, intermittent sore throat and feeling slightly feverish. The tinnitus has been worse on some days. Interestingly, since starting the niacin, I’ve noticed some sneezing and, inflamed eyes and generally classic histamine/allergy feeling. Haven’t had this before during any of this. Anyone else experienced this?
@@RUNDMC1 I live in Brooklyn, NY. Until recently, most doctors that I’ve seen told me it was all anxiety- I thought I was crazy until I came across your channel. You’re doing such amazing work.
I have good feelings about it. Im already feeling much better. I was already taking everything but the b3. That made all the difference. good luck to you
Please heed the advice to start B3 on a low dose. I took100mg, The "flush" was much more than expected and I spent the evening in A&E. I still have brusing around my eyes from the swelling. Not recommended!
I was already following an "anti-inflammatory" diet since contracting Covid in March, but following the last video, I realized that I had to add/delete a variety of foods and supplements and made those changes to the best of my ability, and I am already seeing some really positive results in my symptoms (almost all of which seem attributable to inflammation, presumably due to a mast cell feedback loop. It now feels possible that with time, I can interrupt that feedback loop. All of my symptoms have shown improvement (neurological, bronchial, gastrointestinal). They are still present, but I've actually been able to cut down on some of my medicine intake for treatment of those symptoms. One of the most dramatic changes was a complete return to normal of my pulse rate and a regular modulated body temperature, consistent to what it was prior to my infection.
@@ChristianSkoda I specifically added a high dose of Niacin, upped my vitamin C, added a pretty high dose of quercetin (already taking upper level doses of vitamins D and K, zinc, magnesium, other Bs. I cut out bananas, spinach, avocados, tomatoes, green tea (I was drinking a lot of that), absolutely all gluten, citrus, and started taking a benadryl every night. I was able to eliminate cough suppressant though still taking expectorant and singulair, haven't thought about using my enhaler, have started to forget/skip my reflux meds; fewer headaches, reduced dizziness and brain fog, fewer memory issues, better word recall. I had no idea until the part 1of this video that there were so many mast cell triggers labeled as supposedly good for you and anti -inflammatory.
From another exhausted, frustrated, and discouraged Long Hauler, THANK YOU!💙 I'm at 8.5 months and just started 100mg of niacin two weeks ago. Though I had a terrible relapse yesterday (first time in months, thinking it may have something to do with my menstrual cycle?). Sticking with the niacin though! I've limited sugar the last few months but am going to try limiting high histamine foods👍. I pray for us all and I cannot wait for the day when we are healed and there IS an answer! Thank you again!
This doctor is amazing, and his story mirrors mine exactly - mild covid, period of exercise, then a crash. And yes, I also have chest pain and tachycardia, with all heart tests showing normal. I have been taking antihistamines and nycin for a couple of weeks now and I am really making great progress! I take all the vitamins too. I just hope I can get more time off work so I can properly recover. I can handle 250mg niacin not too bad, but will probably now split it 150 x3. Thank you both so much, you have given me hope that I can get my life back!
Your input on long covid is truly appreciated. I have implemented some of the advice from your channel and I have seen improvements. It gives us all a little nugget of hope. Thank you!
A thousand thanks to you for sharing the best summary of the most relevant information about Long Covid. You're such a blessing to so many of us fortunate enough to have found your channel. Thank you for interviewing Dr. Wentzel, and also for summarizing the high points from Part 1 of your excellent "Biology of Long Covid" series. I love all the detailed information, too--and paused this video at several points to better absorb the significance of some of these key puzzle pieces you've been finding. And thanks for the good laugh at the end!
My apartment is looking like a pharmacy. No improvement 1 week into the regiment, but still hopeful, with Dr Wentzel saying it can take months even. As always, thank you for another extremely useful video.
thanks for posting; i too have quite the collection of additives. day 5 for me, and no improvement w wretched fatigue. i also do Intermittent fasting and keto. and still hopeful too! and persistent.
thank you so much. I started the stack right after your last video and have been getting great results. So grateful to be mostly rid of that body buzz and tinnitus.
@@frankttom4990 I had a few really good days. then relapsed badly. Today is better. Im at week 1 as of today. the follow up video to this says 1-2 weeks. So we will see.
Im starting to feel like my piece of the puzzle is the one my younger sibling lost the last time they put the puzzle away. Im blessed to only have leg muscle weakness, but it does feel a bit like a one off. Thanks again for keeping us informed!
Run-DMC, one supplement (in addition to those you discuss) that has been over the top healing to me so far (other than high Vit C) has been high doses of Magnesium Chloride. I think that cfs and long covid get triggered when the adrenal gland gets gassed and can't keep up with long term infection fighting. Then, the body can't clear the virus, then the NAD problem and MAST cell issues come on. The body stays in this low energy state, preventing it from clearing the virus, because the adrenals and thyroid can't keep up, so they go off line. All of the inflammation from the Mast issues compound the issue, convincing the adrenals to stay off line. The key is to convince the adrenals and thyroid that they can turn back on at full energy, either by lowering pathogen levels or adding enough nutrition to significantly lower the inflammation. So to my mind, supporting the adrenals and thyroid with what they need is as important as addressing the Mast Cell inflammation. Thyroid needs Iodine, Selenium, B vitamins and Zinc. The adrenals need 2 things in huge amounts to survive a long infection: Vitamin C and Magnesium. Most animals make their own Vitamin C. Humans do not. Linus Pauling who discovered Vitamin C took 20 grams (not mgs) per day, to give you an idea of what he thought was a health optimizing dose. Magnesium is arguably needed in just as high doses. Interestingly, I stumbled upon Magnesium Chloride because I was looking for an anti-viral that would kill Covid, as my previous success with CFS involved killing the virus, ebv. Magnesium Chloride kills almost everything apparently, but at the same time does not add stress or inflammation to the body or damage tissues because its magnesium. It is a tonic that aids sleep and ends anxiety and palpitations. A doctor named Pierre Delbet discovered that Magnesium Chloride had this magic during WWI, and he used it against polio and many other things. I have linked a website here that describes how I take it. I am currently taking 3mg, 3x per day dissolved in water. It's cheap, and it is the one supplement I take (I take a ton) that brought me up about 40%. I plan to take it long term, because I am hoping it will kill covid and support my adrenals. It increases immune function by 300%. Only magnesium chloride by mouth, not any other kind of magnesium will work. Here is the link. www.mgwater.com/vergini.shtml If it works for you, perhaps you can share about it on your channel. I find it fascinating that mainstream medicine rejected their attempts to promote it as an anti-viral and antibiotic in the 1930's and 40's in favor of vaccinations.
Thank you Gez! Taking niacin has helped me greatly in just a week. The dark circles under your eyes have really improved! 😯 We are seeing the changes with each video. 🙌🏼
@@karlaadair6540 why did I think it needed to be taken three times a day after a meal? Did you start out at 500mg ? And when did you notice a positive change?
@@browneyedgirlFL67 it just felt powerful and like it was plenty so I just listened to my body. My tongue felt less “swollen” in about 3 days. Felt less fatigue in about 2 weeks.
With all this new info and "pieces of the puzzle" coming to light, I wonder what all this new research might mean for the study of other diseases and conditions having nothing directly to do with covid 19. It would be nice if it sparks whole new lines of study deeper into the biochemistry and metabolic effects involved in those other diseases - and finds new answers and treatments no one knew to look for until now. If so, that would finally be something good out of covid.
Gez, this is the first time I have added in a comment from sunny (Summertime now), South Africa. I'm 6 months in with brain fog, fatigue and chronic, constant, unbearable pain in my left leg running down from my Covid induced arthritis in my hips. On Monday I am having an MRI on my spine and hips. Thereafter, nerve conduction testing in both legs as the doctors are thinking neuropathy, and as a diabetic who was fit and reversing the type 2 condition, diabetic neuropathy. I have been so alone in my struggle with this fickle, dishonest virus and your input is greatly appreciated and I value your tireless research, in spite of the restrictions, greatly. You are my "Be the change with Covid' hero. You have cheered me up with this latest video as you are looking a tad perkier.
Thanks Anna :) I really hope you start to recover soon. I do recommend the treatments I’ve talked about in my latest films - got a study that shows they actually work coming out with my next film. Dr Wentzel is on to something!
@@RUNDMC1 thanks SO much for your helpful videos. best of luck. i located this protocol summary: membrane.com/world/ but am unable to locate the study results. Have you a link? i'm taking 500 mg niacin/day, for 7 days now. still enormously fatigued. no improvement. yet. and i still do Intermittent fasting and keto. guess it can take months? esp if one is already NAD depleted. thanks again!
This is fascinating! Thank you so much for your efforts, putting this together, Gez. Hopefully , in time this regimen will bring the much - needed relief to many Long Haulers and COVID will have finally done us a favour in understanding genetic changes and damage to metabolic pathways as part of disease etiology. Cx
Thank you Gez!!! Thanks to Dr. Wentzel and his team for this gem. I wish I had this information before developing POTS. Hope that this is the answer that I have been looking for 9 months.
There are millions of people worldwide, suffering for decades with post-viral illness (me/cfs). I hope that this information can also be directed to them, as they've had NO HELP so far &, in fact, have been dismissed as having psychiatric illness.
@@RUNDMC1 have you tried fasting at all? I’ve been reading that a mixture of intermittent fasting, twined with a 3 day water fast will induce autophagy and perhaps clear out some of the virus that might still be in our bodies?!
Something of a genius Gez! Absolutely love the interview, wish I could have been a fly on your skis - very interesting that he doesn't recommend non-flushing Niacin. Did he say why? As always, thanks for a very clear vid!
Gez, sorry if it's already been asked, but how are you feeling on the new regimen? Improved? I've been ill since June, and the supplements & diet change have made an improvement over the last fortnight or so, but I still need 12+ hours of sleep. Thanks so much for your videos and hard work over the last few months, despite your own illness -- they have been so helpful in so many ways. :-)
I focused on Adenosine. It converts to inosine naturally in hypoxic conditions and is helped by Adenosine Deaminase but that enzyme (which is co-located with DPPIV which is a Covid receptor) is easily taken out by Covid. It is the perfect biomarker or messenger for vascular tone modulation but in the absence of Adenosine Deaminase you need to reach hypoxia for the anaerobic conversion to take place. Incidentally DPPIV also caters for (cleaves) Bradykinin and a supercomputer later suggested it could be a Bradykinin storm some months after I published my conclusions. Look up Adenosine Deaminase Deficiency and Severe Combined Immune Deficiency. We differ from other mammals in that our Adenosine Deaminase is co-located with DPPIV. Did I mention DPPIV also an Angiotensin Converting Enzyme?
Niacin is a precursor, a building block that helps the body to produce NAD+. However, you can take NAD+ itself, orally, via liposomal NAD+. Liposomal NAD+ is simply NAD+ encased in a liposome capsule that protects the NAD+ from being digested in the gut and delivers it to the cells where it is needed to produce energy. Liposomal NAD+ is available on Amazon.
Hi, thank you from across the pond for these videos. They’ve given me hope and answers I’m not getting from my doctors. As evidence to support this NAD+ deficiency theory, due to ongoing symptoms 8+ months later my doctors tested my 5-HIAA levels. I had massively elevated levels, which led to a PET scan that thankfully came back normal. The most common reason for elevated 5-HIAA (a serotonin byproduct) is a carcinoid tumor. My doctors are saying my symptoms and cause of elevated 5-HIAA remain a mystery. It seems to me, however, that my test results may provide proof of the COVID affect on the NAD+ tryptophan/serotonin/IDO/5-HIAA to mast cell activation pathway theory. Curious if this tidbit helps any of the doctors with whom you’re speaking?
you have to look into this doctor: he has an explanation for the serotonin-syndrome "Farid Jalali MD on twitter : ".One such platelet mediator is serotonin. Plasma serotonin is kept at tightly regulated low levels by storing 95% of body's serotonin in platelet granules Serotonin is uniquely positioned to 𝗮𝗰𝗰𝘂𝗺𝘂𝗹𝗮𝘁𝗲 in COVID19, as it's released copiously and its reuptake is impaired....." "There is clear evidence of plasma serotonin 𝗲𝘅𝗰𝗲𝘀𝘀 in COVID19, with this excess being a result of platelet degranulation, combined with the pulmonary vasculopathy and endothelial dysfunction of COVID19, the same endothelium that is responsible for reuptake of serotonin.""It is paramount to understand the signs of serotonin toxicity, and to recognize that there is 𝗼𝘃𝗲𝗿𝗹𝗮𝗽 between ARDS / sepsis and the signs of serotonin toxicity Distinguishing signs of serotonin toxicity include - Myoclonus - Hyperreflexia - Severe agitation - Diarrhea"and so on
@@erocalypse21 did you find help yet? I just came across covidlonghaulers.com Havent checked them out yet, but the vid said they would list the tests you should get and work with your GP. Wishing you all the best.
Anyone else tried getting lots of quality sleep and meditating and other forms of brain/body calming as part of your attempt to speed your recovery? I think these are forgotten ingredients in other recovery regimines. I've been watching a lot of good videos (like this series) and reading articles and have come up with a vitamin/mineral regimine (as specified by MCAS and NAD+ research), but those only helped me get back into the incremental, very slow recovery phase (I'm in my first relapse and experienced recovery this way before) instead of a faster recovery mode. Obviously lots of good quality rest could be important to tip the Long Covid internal balance towards reestablishing our normal homeostasis. (Symptom, insomnia) But with all the extra cortisol and other inflammatory hormones and chemicals we get from both the heightened (Symptom:) anxiety caused by Long Covid and the additional stress and anxiety we are getting from out society gone mad (not to mention loss of loved ones), this could also be supporting the new homeostasis of Long covid.
Quality sleep doesn’t come easy to many of us. A symptom is still insomnia regardless of what you take. I can take melatonin and fall asleep relatively quickly but the issue is staying asleep. No amount of rest makes me feel refreshed, regardless.
This is exactly what symptoms I have experienced with Chronic Lyme Disease...along with millions more. But, the doctors don't admit we exist...I hope and pray it does not happen to the long haulers...of which I am one. Pots was a big symptom with me in the beginning...still have to sit with my feet elevated...
Have you looked into ivermectin to treat long COVID if someone has a live COVID reservoir? I’m a recovered long hauler. Around month 6, I took a 4 day course of ivermectin. I felt a difference after 1 day and all my COVID symptoms were gone on day 2. My health has been 100% since with no further relapses.
@@evanmaxwell4649 sore throat, runny nose, body buzzing, breast pain, pain in previous recovered injury, fatigue, brain fog, shortness of breath, shoulder pain, loss of sense of smell, heightened allergies, high heart beat resembling POTS
Thanks for all you do Gez! You will deserve a knighthood by the end of all of this!!! Buying the niacin now, adding it to my large collection of supplements, fingers crossed! The dietary supplements industry must be doing well this year! ;-)
Bravo! Bravo! Thank you, Gez! We are finally getting a better understanding and and encouraging news it's not likey to be permanent! I so needed confirmation on this! And tonight is Day 8 of Hanukkah... it's a Hanukkah Miracle!! 🤩
Thank you so much. The onset of symptoms after exercise describes my experience 100%. I have always wondered why ultra-fit people seemed to be affected to such an extent. It seems counter-intuitive. I am going to start with the recommended supplements immediately.
Yes - I think ultra fit people have already been running with borderline NAD+ deficiency due to the heavy training. Makes sense with my experience too.
When you ask your body to do things, your body needs more air to be able to do it. The gas exchange in the lungs is different than when you are not doing anything. Women are more affected by men by the crap in the air because of the differences between men and women, this is why women are more likely to have systemic disfunction (autoimmunity) than men. Toxic overload. www.amchara.com/genetics-dna/gender-differences-in-chemical-exposure journals.physiology.org/doi/full/10.1152/jappl.1998.84.6.1872
I've got ongoing symptoms but did nothing other than moderate to light exercise after covid. I perhaps wonder if the cycle rides I did a couple of days before I displayed symptoms has caused my experience. I used to happily bike 15 miles each way for dinner in my parents garden. It knowing when I am ok to start exercising again, the last thing I want to do is set myself back.
Many thanks for your incredible work! I think you help more people than the average doctor. I wonder if creatine could have a role in the stack? It works with ATP/energy in the cells and also makes you load up with water in the body which may be helpful. Would be great to know more about it. Looking forward to your next video.
Thanks again Gez, like someone else said, these videos have been more helpful than my GP. Could I ask, are nicotinic acid, niacin and vit B3 all the same thing?
Hi, there is a good definition here www.healthline.com/nutrition/niacin-benefits Nicotinic acid: As a supplement, nicotinic acid is a form of niacin used to reduce cholesterol levels and lower your risk of heart disease. Niacinamide or nicotinamide: Unlike nicotinic acid, niacinamide doesn’t lower cholesterol. However, it may help treat psoriasis and reduce your risk of non-melanoma skin cancer. My organic chemistry is a little rusty but I think I've bought the wrong ones. I got some H&B Niacin (vitamin B3) which when reading the small print is Niacinamide based - no good according to the paper in the video. I need to get some 'pure' Nicotinic acid which I'm struggling to find. Please let me know if you locate any. Cheers : D
Hey Gez! first off thanks for this invaluable content. You ROCK Second, as request: Could you ask Dr Wentzel about Resveratrol? I've read some interesting things that as well as Quercetine it can promote autophagy which could be beneficial to get rid of V. presence in gut, although some studies suggest that if combined, the effect is actually reduced... Thanks in advance mate!
Gez, you're a genius! And also a true HERO for all who are suffering this condition. A million thanks for your videos! How do you take these supps (meal wise)? All of them at breakfast or do you divide them between three/four meals a day?
I have been suffering for a while now, I had an event in August which I thought was either a heart attack or a stroke. It turns out it was a stroke, I am a generally fit and healthy 30+ year old. Since being ill in March I have suffered quite badly with palpitations and dizziness. I am still under investigation at the moment.
Awesome content, thank you! I've been taking Niacin for a while, MCAS symptoms improving a bit but still there. Would adding Methylene Blue be something to consider?
It would be good if you did another interview with Dr Wentzel to see how he and his patients are doing now some time has past taking his supplement stack?
I was taking the stack via a lady in contact with Dr wentzel. She blocked and deleted me when I told her the niacin induced a depressive episode in me. The results are therefore skewed! Not taking on board people who have had negative effects from the stack.
@RUNDMC1 I can’t decipher what is being said at 9m-21s, where the discussion was a large correlation of long haulers had pre-existing conditions. One was “Rheumatoid Arthritis”, and the other was “ATP”? Not sure I understand ATP… didn’t think “ATP” was a pre-existing condition…. Maybe ATP dysfunction? Same at 14m-05s. “Nicotinic Acid blocks the loading bay that prevents the “sump” from tryptophan to Nicotinic Acid Mononucleotide. What’s a “sump”? Can someone translate that sentence for me? Thanks! Wonderful Content.
I love these videos you are doing. I appreciate all this information too. Is it possible that the autoimmune and mast cell.could all just be a genetic mutation one have and some don't have that reacts to Covid 19. Something that can cause chronic illness's in a specific area or to a specific system that like I said Covid is re-activing to? I have eds, mcas and pots and I know there's a genetic mutation that's causing it tho they haven't found it for the hypermobile type. Do you think the real answer is in our dna with the people are are just more seasonable to chronic illness like my own? Before Covid I had A LOT of theories when it comes to genetics and this kinda feels like i could be an over all genetic susceptibility mutation that we've just never seen before. or maybe get something we have seen over and over like those who end up with fibromyalgia and pots after getting sick with a cold or a virus period maybe there is a genetic susceptibility to these issues when the right Gene is activated by a virus? I'd truly love to hear what anyone else has to say about this theory.
many long haulers have noticed big improvements by taking L-glutathione, and wondering if anyone can comment on if glutathione is related to the NAD+ processes that are being looked at currently?
The late Dr Konynenberg successfully treated CFS/ME patients with glutathione precursors. Maybe rectifying glutathione levels or NAD levels produces the same outcome of restoring tryptophan? 🤔
The main gap in this theory, in my opinion, is that the enzimes that are missing would eventually be produced by the body again after some time. If they aren't it means that I will have to take niacin suplements forever.
@@RUNDMC1 So why long haulers don't get better by themselves, without any treatment? I have very mild long covid symptoms, they are mainly chills, but I cannot workout. The next few days I feel completely exhausted.
@@paulocl2 they do, from what I've gathered it takes around six months to a year for it to get back to normal levels, and it happens gradually so it might be hard to notice that it's getting better.
When they talk about the tachycardia symptom related to this, can I assume they mean that all of the POTS symptoms fall into that? Low blood pressure, chest pain, the palpitations and orthostatic intolerance? I’m wondering where to draw the line between NAD deficiency and actual POTS
Thank you, Gez, for another fantastic report (I agree with those who've said you deserve official recognition for your work - and, yes, a knighthood would be appropriate :-)). In light of this information on NAD+, I'm thinking that a combination of physical rest and reducing my stress/anxiety was key to the significant long-covid improvements I started noticing around the 5-month mark (Dr. Google confirms that stress really sabotages NAD+ levels). I have an exercise-related question, either for you or anyone else who's inspired to answer. I've been back to exercising since August (initial infection was March), working on returning to my pre-covid fitness level. Recently (i.e. over the past couple of weeks), I re-introduced some fairly hardcore interval training (I also had a couple of unavoidably sleep-disturbed nights). And .... wham. Moderate relapse. I'm not suffering the way I was in the summer, but I'm abnormally fatigued and dealing with some joint pain. I've started taking niacin (just 50 mg/day for the past 3 days, but I'll be increasing - apple pectin seems to be keep the flush away). But now I'm wondering ... Should I be going back to NO exercise? I seemed to be tolerating it well before the high-intensity stuff (and bad sleeps). Or should I just avoid that stuff ... and, if so, for how long? I'm curious about Dr. Wetzel's comment that he is now back to 3-hour windsurfing sessions, given that he is still taking niacin supplements and thus implicitly hasn't yet returned to his baseline NAD+ level. Many thanks again!
It does seem we’ve got to be super careful with strenuous exercise in recovery. I would take a week off completely, then start to slowly build it back in at a low level but avoid the interval training. Perhaps do a light interval session in a few weeks as a test but definitely don’t push yourself to exhaustion in that session!
@@RUNDMC1 Sounds like a plan, Stan! Thanks! When the time comes, I look forward to hearing about your fitness recovery journey. I'm thinking many of us may *not* be returning to brutal, punishing exercise programs - not because it's physically impossible but, rather, because the longterm health costs are so high.
Wow - this is a lot more than I can tolerate after 5 and a half months of Long Covid... have not been able to do any more exercise than simple walking. I used to exercise 5/6 days a week prior to L C - running, weights/gym type, ashtanga yoga - and an avid surfer. Envious that you’ve returned to some form of it already...!
@@RUNDMC1 very sorry to hear 😓. It’s hard. Also considering how seriously de-conditioned we all are. I lost about 4/5 Kg... take it easy and thank you again for this amazing work you’re doing. Just started the supplement cocktail you recommend will let you know how it goes. At first I was a bit skeptical about L-C / MCAS link precisely because of the huge list symptoms which made me think it could just claim to be the source of every illness under the sun. But these recent videos about NAD + deficiency are fascinating. If you have time I’d love to hear your thoughts about the insuline issue which I tagged you in, in another comment 😅. It does feel relevant to me... Good luck and thank you again deeply for sharing your research so eloquently.
Another great video, I really enjoy these and it seems you are using decent scientists and medical staff for the content. I have started with the supplements as suggested in your video, I'm hoping there will be a positive in terms of my reaction to these. I do have a couple of questions for you, what are your principal ailments since catching covid? How badly were you ill with your initial symptoms? and finally how has your health improved over the last few months? I do hope there is more significant improvement with your health. Thanks again for the amazing videos.
1) Brutal fatigue, headaches, cognitive issues, skin issues, palpitations, histamine intolerance, exercise intolerance 2) initial symptoms weren’t that bad - felt like a cross between a mild flu and norovirus. 3) Better the last 2-3 weeks after starting the various treatments and being more assiduous about low histamine diet.
@@RUNDMC1 I certainly share the fatigue and exercise intolerance, I suffer a lot with muscle pain and sometimes I am short of breath. Like you my initial symptoms were flu like, the first week was dominated by fatigue, muscle ache and weakness, in the second week I became short of breath and had chest pains. Glad to hear the treatments are working for you, I am following a similar path, I will go low histamine after Christmas. I hope your recovery continues.
Great video again, is niacin the same as vitamine B3? Since when i Google it, I will only get this (in NL) also I started low carb carb high vegetable diet and only eat on 3 moments a day, so you intestines that are a big part of the immunesystem, also get some rest during the day. For me this is starting to work. And pacing is also very important.
Beta blockers and Oral Hydration salts. (Brands that have the formula the WHO recommend) Also try Low Dose Naltrexone because a friend reversed his POTS with LDN He said most the others he was talking to online reduced their POTS too with LDN (start very very low though like 1mg and work your way up by increasing once a week, see if there’s any improvement. When you improve well that’s the dose you stay at) for some reason people seem to have a better affect than carrying on increasing the dose. (The average LDN dose is around 3 mg to 4.5 mg) People who rushed this medication can get very sick so you’ll see everyone saying “go low and slow”, with tiny incremental dose increases of 0.5mg. About once a week or at least 3 to 4 days of feeling okay before the next dose increase Good luck
Hi, Have you heard of anyone taking this stack with persistent abdominal pain, recurring fever and joint pain, improving their symptoms? 6 months of enduring with no improvements. Thank you for your much needed guidance in this difficult time.
Hi run, on your diagrams it looks like nicotinamide feeds into atp? Yet I hear what he's saying... that it has to be niacin or nicotinic acid introduced slowly... the flushing is so annoying
I’m not sure if you’ve heard of NAD IV therapy infusion. Its a type of natural treatment to boost cancer patients energy level. It’s available in the US. I wonder if this is something that we can benefit from since it goes straight to the blood.
I've been taking multi vitamin tablet which included 75mg of B3. Not sure if that's enough. So I just ordered a 250mg slow release B3. Will see if that's effective in a few weeks.
Looking back, think must have been helping myself and not knowing it. I did not eat a lot of cereal. All of sudden when got Covid (In March) I kept wanting to eat it. Guess my body wanted the Vitamin D in the milk? Plus I drank "Airborne" every day. Which has many of the vitamins and zinc suggested. Now I still take a supplement of D and a vision formula vitamin. My retina's are "thinning" now. Had an issue with my wrist which think turned out to be a blood clot. That has gone away as well. Going to still take the vaccine when I qualify. Just as a booster. Was waffling on it as have had covid long term. However, it sounds like a good idea overall.
Is it possible a viral infected cell could produce viral antibodies after infecting a antibody producing immune cell? Has there been any studies(or can there be) looking into whether or not antibodies are still produced by antibody producing immune cells after becoming infected with CV19? A few different reasons reduce immune cell count to area of infection or a organ examples, a virus infecting a cell, reduced blood flow to area of infection, poor bone marrow and thymus. Immune cell deficiency also causes antibody deficiency. Antibodies bind, attach, neutralize, build and allow for communication. Immune cells are mobile antibodies are not, possibly the mobile cytokines bring the proteins to develop antibodies at the area of infection delivery could become hampered due to constricted blood flow caused by fluid and debris buildup in the lungs this could be similar for any organ.
@@RUNDMC1, thx for responding. Hopefully my questions could someday be helpful, my questions may be off the wall or out of the box but I think that's ok at this point to present any ideas that may lead to an educated expert to consider possibilities he may not have considered, sometimes a lot of education can lead to blinders being a long way from basics, even more now that there's is a new strain that there claiming it's more contagious and causing less severity of illness this new strain could easily mutate again and become more deadly similar to what we were hearing out of woohan at the start when people where dropping in the streets. There's no way of knowing how long the Spanish flu circulated previous to being recognized and whether or not the vaccine that was introduced at the time had any effect on herd immunity that was achieved then, in regards to mutations and variances. I firmly believe what they're calling vaccines are treatments due to the fact adaptive immunity is unproven at this time, adaptive immunity takes years to prove, I'm not against the treatments(or what they're calling vaccines) these treatments are innate system boosters and are effective, that's good, it's definitely a breakthrough in medicine and there has been a lot learned recently, there is something missing though the answer to how these start could someday be answered it may not be through the petri dish.
I'm waiting to see data about the side effects of the various vaccines on autoimmune disease patients. I have Antiphospholipid Syndrome and am going to be very careful about about being vaccinated.
Love your videos on covid. They've given me hope. Though it's only been about 2 weeks, I feel many of the common symptoms of a long-hauler. I have some questions. Does whether you end up with long covid depend on the amount of viral load? Is recovery more likely the younger you are? Does having pre-diabetes or type 2 diabetes affect your chances of getting covid-related dysautonomia or pots? What about binge-drinking? What affect do SSRIs have, if any, on long covid? What can we do about hyperadrenergic tachycardia, insomnia, and anxiety? Thank you from California. 🙏
Hi Michael. To try and answer your questions: 1) we don’t know 2) age not a factor in recovery 3) diabetes not correlated with LC generally, can’t say for dys/POTS 4) Stop drinking immediately! 5) SSRIs seem to help seratonin levels, and thus sleep and energy generally
Really appreciate your input and advice re long covid. I share all your videos on the Irish Covid Cases group I belong to. I'm almost 9 months in now, symptoms mainly breath shortness, fatigue, heart racing. 6 months in when cardiac mri diagnosed myocarditis. Taking NAC, Ubiquinol, Zinc, VitD and multivitamin for some time now. Just started Niacin after seeing your video. My question is.. is it safe to take while on low dose beta blocker? I read that niacin can cause low blood pressure. Mine is already very low. Sorry for long post! Thank you!
I bought a 500mg sustained release Nicotinic Acid that will prevent flushing. In your research is the sustained release ok, or is the flushing somehow necessary?
Very interesting thank you , I’m starting to think normal life is over for me now , I’m working but into my 9th month of poor health and eye sight affected , dr won’t help me , not much hope anymore
I got better from long covid after 6 months from onset of symptoms. I have a family member that works in a hospital and she came home infected. I'm now on my second stint of having covid. This time is much different. It affected my liver/spleen/gut/brain the first time. This time it's all upper respiratory. :(
I have yet to see a doctor with 10% of the information that you've dug up - thanks to you and other researchers, I bring most of the knowledge to my meetings with doctors. And they charge me. Going to have to look at that... ;)
Love these videos, thank you! For those of you doing this - are you taking as low a dose of Niacin as Dr Wentzel recommends? My local Holland and Barrett only had 500mg...
and experiences with flush/no-flush are appreciated too. Dr Tina Peers recommended no-flush so I bought that, but Dr Wentzel says there are side effects with this
If you don’t get the side effects then don’t worry! You can find 50mg on Amazon, but try chopping the 500s in half and just taking some of the powder, see how you get on
Hi. Great videos. Extremely helpful and hope inducing. In this video do you know if the recommended Niacin dosage of 25mg 4Xpd was per Kg body weight or is that just an adult dose?
yes this is my main symptom. I'm constantly inflamed. My ENT doc gave me prednisone and flonase, none of which seemed to help. She also had me to some nasal irrigation, which I almost feel made it worse, it made me feel even fuller and more pressure in my ears and sinuses. I'm at the point where I'm taking matters into my own hands now, I'm going to start these vitamins and I've changed/am changing my diet. I don't think the docs know enough yet, there def needs to be more push into research for these lingering effects. This channel is giving hope and I'm thankful and eager to start these modifications.
The doctor discusses different types of individuals, some who can recover in weeks and others in months. He uses certain terms in relation to each group. I'm dizzy, bad walking, and slowed processing of visual information. Which of those groups would I fall into? My situation was set off by heavy exercise a month after recovering from COVID.
@@zacs5773 I lost my ability to walk for a few days. Spinal tap, MRI, lab work - nothing! The docs were clueless. I've been real sick with this for a month. I can't work or do much of anything that doesn't involve my bed. I had no idea there were so many people with similar stories.
@@scripturethroughancienteye1509 You and me both, I still have days when my legs don’t work properly. I’ve lost count of the blood tests I’ve had that say there’s nothing wrong with me. It’s been really tough for me when I used to play tennis 5 times a week and cycle 100 miles regularly. I have cycled my bike for months. I do hope these supplements work 👍🏻
@@zacs5773 Man I was in the gym everyday. I have lost twenty pounds since the onset of this post-covid thing one month ago. It seems that exercise is coming up more and more in these stories. I tried to exercise my way out of this and ended up much more sick.
I recently purchased Niacin (inositol Hexanicotinate) 500mg flush free. Is this an acceptable type of Niacin or should switch it out for something else???
Hi gez, thanks a lot for this research. How many months are you into long covid ? I'm a 6 monther and I have high heart rate on standing/exertion and slight brain fog which seem to persist since past two months. I'm already taking Fish oil, magnesium, b complex tablets. What's the dosage that you'd suggest for niacin ? I'd love to try that and I hope it works for me.
Good work again I'll be getting the stack this week can you recommend if it's safe to take with pregabalin along side the stack? as fatigue and Nero issues are my main problems at rest right now thanks 😊
Hey, thanks again for all your hard work and research. On the antibody tests, I like many long haulers tested negative with the Roche test. I believe it tested IGM and IGG however, I recently took a Sarsplex test and my IGA antibodies where nearly 3000, that's 3 times what is needed for a positive and that's 9 months after the initial infection. I have also learned of others getting the same results. Could there be something linked to this type of antibody? My personal feeling is, that the Virus was present in me for the first 4 months as my body invited it in for a party before realising this little bollocks was going to kill me, then decided to deal with it. I have gotten a lot better from month 5/6 however, I now feel like I am dealing with an autoimmune disorder. It's been like a disease of 2 half's, that has not finished yet. First the virus and secondly the autoimmune reaction driven by an overactive immune response and a high antibody count (only IGA) Agian, thanks for everything. In my darkest days, your research and videos give me hope. Take care.
@@RUNDMC1a few people from the Bodypolitic slack group have had the same Sarsplex results with the IGA Antibodies. Most of the other antibody tests don't look at IGA, they focus on IGG and IGM only. My wife who I caught this from has the IGA and also IGM 9 months on. She had a sore throat for 2 days and no other symptoms. Typical lol. I was pretty much using the supplements you have noted in your videos however, I also use CBD and it makes a massive difference. If I can ever help with anything, just let me know. All the best.
@@frankttom4990 hi, I still have a lot of lung burn and muscle pains around my chest and back area along with some debilitating joint pain. I also get a burning sensation in my blood and throughout my body. Dr Paul Garner described this as having chillies in the blood. This is brought on greatly by talking or doing anything physical. I find the CBD relieves this or of you can get the real oil,, it 99% removes all these symptoms. It’s unbelievable. All the best
@@RUNDMC1 thanks, that's what I was assuming. After watching the senate hearing, I am saddened and angry over the increased devastation to Americans by the general discrediting of these treatments that could have either stopped or greatly lessened this disease in most cases.
![Run Away - Tzuyu(TWICE) ツウィ 쯔위 [Music Bank] | KBS WORLD TV 240906](http://i.ytimg.com/vi/KnHNNyAYiu0/mqdefault.jpg)
I started on 500mg of niacin last Friday and whoah, DO NOT DO THAT, FRIENDS! I ordered some 50mg pills and have been on them the past few days. I honestly am feeling better. My brain is working again, my body temperature is starting to regulate a bit better, tinnitus is quieting and my breathing starting to almost feel normal. Thank you so much for these videos. You’ve helped so many people!
Thanks Greg! And yes - 500mg of Niacin can be quite the rush!
Greg Garner, which other long haul symptoms did you have? Was your tinnitus also variable depending on the day?
I started with 1x 250mg Niacin capsules once a day and upped to 500mg after 1 week (taken after lunch), controlling the flush comfortably with 1x aspirin taken before lunch. Should I reduce the dose better again or keep it that way, as it's bearable? I'm 2 weeks at it and there is a slight improvement in energy, although nothing dramatic.
@@frankttom4990 I first had symptoms back in the middle of March but wasn’t able to get tested until three weeks later and the Covid test was negative. Also tested negative for antibodies. But I’ve had breathing issues, tachycardia and palpitations, fatigue, hot skin which leads to feeling cold, intolerance to exercise and direct sunlight, tinnitus off and on but more pronounced since October, intermittent sore throat and feeling slightly feverish. The tinnitus has been worse on some days.
Interestingly, since starting the niacin, I’ve noticed some sneezing and, inflamed eyes and generally classic histamine/allergy feeling. Haven’t had this before during any of this. Anyone else experienced this?
Christian Skoda Bring it back down to 250 and keep it there for a few weeks
These videos is the only thing i look forward to at the moment. Thank you very much for helping all of us suffering.
You and me both. Honestly such good work
@@5ilentRage You and me and August! A lifesaver.
Hang in there. It will get better slowly.
You’ve been significantly more helpful than any doctor I’ve seen in person. Thank you!
Sorry you’ve had such a rough experience Meir. There are good doctors out there! Where are you based?
@@RUNDMC1 I live in Brooklyn, NY. Until recently, most doctors that I’ve seen told me it was all anxiety- I thought I was crazy until I came across your channel. You’re doing such amazing work.
so true!
@@meirwilenkin9218 me too
But why are most doctors no helpful?
God, I really hope this is it... I’ve just ordered these supplements as I’ve had this since March and want to get my old life back. Thank you
We all want our old lives back! Best of luck in your recovery Zac 👍
I have good feelings about it. Im already feeling much better. I was already taking everything but the b3. That made all the difference. good luck to you
Please heed the advice to start B3 on a low dose. I took100mg, The "flush" was much more than expected and I spent the evening in A&E. I still have brusing around my eyes from the swelling. Not recommended!
Phil Weaver glad to hear it!
Please see my other comments; the changes I'm seeing are pretty dramatic.
I was already following an "anti-inflammatory" diet since contracting Covid in March, but following the last video, I realized that I had to add/delete a variety of foods and supplements and made those changes to the best of my ability, and I am already seeing some really positive results in my symptoms (almost all of which seem attributable to inflammation, presumably due to a mast cell feedback loop. It now feels possible that with time, I can interrupt that feedback loop. All of my symptoms have shown improvement (neurological, bronchial, gastrointestinal). They are still present, but I've actually been able to cut down on some of my medicine intake for treatment of those symptoms. One of the most dramatic changes was a complete return to normal of my pulse rate and a regular modulated body temperature, consistent to what it was prior to my infection.
Very glad to hear of your improvement Jane!
Jane, could you elaborate a bit more please of what you added & removed from your anti-inflammatory diet? Thank you!
@@ChristianSkoda I specifically added a high dose of Niacin, upped my vitamin C, added a pretty high dose of quercetin (already taking upper level doses of vitamins D and K, zinc, magnesium, other Bs. I cut out bananas, spinach, avocados, tomatoes, green tea (I was drinking a lot of that), absolutely all gluten, citrus, and started taking a benadryl every night. I was able to eliminate cough suppressant though still taking expectorant and singulair, haven't thought about using my enhaler, have started to forget/skip my reflux meds; fewer headaches, reduced dizziness and brain fog, fewer memory issues, better word recall. I had no idea until the part 1of this video that there were so many mast cell triggers labeled as supposedly good for you and anti -inflammatory.
@@janeathome6643 Hi Jane - how high was your niacin intake? I’m taking around 150 mgs a day
@@itstolgs 300 mgs, but I'm older than you.
From another exhausted, frustrated, and discouraged Long Hauler, THANK YOU!💙
I'm at 8.5 months and just started 100mg of niacin two weeks ago. Though I had a terrible relapse yesterday (first time in months, thinking it may have something to do with my menstrual cycle?). Sticking with the niacin though! I've limited sugar the last few months but am going to try limiting high histamine foods👍. I pray for us all and I cannot wait for the day when we are healed and there IS an answer! Thank you again!
That’s OK Jenny. Hope it helps with your recovery!
Gotta love a man who drops an heironymus bosch painting with sound effect into a covid video lol
Knew someone would appreciate it!
@@RUNDMC1 it gave me a good belly laugh!
This doctor is amazing, and his story mirrors mine exactly - mild covid, period of exercise, then a crash. And yes, I also have chest pain and tachycardia, with all heart tests showing normal. I have been taking antihistamines and nycin for a couple of weeks now and I am really making great progress! I take all the vitamins too. I just hope I can get more time off work so I can properly recover. I can handle 250mg niacin not too bad, but will probably now split it 150 x3. Thank you both so much, you have given me hope that I can get my life back!
Another excellent video - and not least because Dr. Richards gave me hope again
Your input on long covid is truly appreciated. I have implemented some of the advice from your channel and I have seen improvements. It gives us all a little nugget of hope. Thank you!
Thank you so much again. This time I almost saw some light in the tunnel
It is out there in front of us Eva!
A thousand thanks to you for sharing the best summary of the most relevant information about Long Covid. You're such a blessing to so many of us fortunate enough to have found your channel. Thank you for interviewing Dr. Wentzel, and also for summarizing the high points from Part 1 of your excellent "Biology of Long Covid" series. I love all the detailed information, too--and paused this video at several points to better absorb the significance of some of these key puzzle pieces you've been finding. And thanks for the good laugh at the end!
Thank you Cynthia! Glad you appreciate it 😊
RUN-DMC your videos are always so intellectually alert and socially adapt. I enjoy hearing from you.
Thanks Nicole!
If you have some time you should check out Dr. John Campbell info on vaccines? Video title pandemic, Tuesday 15th December.
My apartment is looking like a pharmacy. No improvement 1 week into the regiment, but still hopeful, with Dr Wentzel saying it can take months even. As always, thank you for another extremely useful video.
Hang tight Tim!
Tim Clark which were your long Covid symptoms and when did you get infected?
thanks for posting; i too have quite the collection of additives. day 5 for me, and no improvement w wretched fatigue. i also do Intermittent fasting and keto. and still hopeful too! and persistent.
Have you got the niacin, it has to be the flush one ... nicotinic acid. It's working for me slowly for sure - good luck
thank you so much. I started the stack right after your last video and have been getting great results. So grateful to be mostly rid of that body buzz and tinnitus.
Glad to hear it’s working Phil!
Phil Weaver, did your tinnitus really improve after this?
And by the way, which other symptoms did you have?
What’s “the stack”?
@@frankttom4990 I had a few really good days. then relapsed badly. Today is better. Im at week 1 as of today. the follow up video to this says 1-2 weeks. So we will see.
Im starting to feel like my piece of the puzzle is the one my younger sibling lost the last time they put the puzzle away. Im blessed to only have leg muscle weakness, but it does feel a bit like a one off. Thanks again for keeping us informed!
I know that feeling (but after taking a lot of supplements, and ashwagandha I can actually feel the muscles reacting again!) Don't give up hope. 🙏💜
Run-DMC, one supplement (in addition to those you discuss) that has been over the top healing to me so far (other than high Vit C) has been high doses of Magnesium Chloride. I think that cfs and long covid get triggered when the adrenal gland gets gassed and can't keep up with long term infection fighting. Then, the body can't clear the virus, then the NAD problem and MAST cell issues come on. The body stays in this low energy state, preventing it from clearing the virus, because the adrenals and thyroid can't keep up, so they go off line. All of the inflammation from the Mast issues compound the issue, convincing the adrenals to stay off line. The key is to convince the adrenals and thyroid that they can turn back on at full energy, either by lowering pathogen levels or adding enough nutrition to significantly lower the inflammation. So to my mind, supporting the adrenals and thyroid with what they need is as important as addressing the Mast Cell inflammation. Thyroid needs Iodine, Selenium, B vitamins and Zinc. The adrenals need 2 things in huge amounts to survive a long infection: Vitamin C and Magnesium. Most animals make their own Vitamin C. Humans do not. Linus Pauling who discovered Vitamin C took 20 grams (not mgs) per day, to give you an idea of what he thought was a health optimizing dose. Magnesium is arguably needed in just as high doses. Interestingly, I stumbled upon Magnesium Chloride because I was looking for an anti-viral that would kill Covid, as my previous success with CFS involved killing the virus, ebv. Magnesium Chloride kills almost everything apparently, but at the same time does not add stress or inflammation to the body or damage tissues because its magnesium. It is a tonic that aids sleep and ends anxiety and palpitations. A doctor named Pierre Delbet discovered that Magnesium Chloride had this magic during WWI, and he used it against polio and many other things. I have linked a website here that describes how I take it. I am currently taking 3mg, 3x per day dissolved in water. It's cheap, and it is the one supplement I take (I take a ton) that brought me up about 40%. I plan to take it long term, because I am hoping it will kill covid and support my adrenals. It increases immune function by 300%. Only magnesium chloride by mouth, not any other kind of magnesium will work. Here is the link. www.mgwater.com/vergini.shtml If it works for you, perhaps you can share about it on your channel. I find it fascinating that mainstream medicine rejected their attempts to promote it as an anti-viral and antibiotic in the 1930's and 40's in favor of vaccinations.
Thank you from Canada (Quebec) ! You are my moral booster. Merciiiiii
De rien Julie!
Oui, moi aussi! Mon Brit favori!
Jackpot! I knew it. Thank you for your devotion 😊
Thank you Gez! Taking niacin has helped me greatly in just a week. The dark circles under your eyes have really improved! 😯 We are seeing the changes with each video. 🙌🏼
That might just depend on whether I’ve shot the video on a good day or a bad day! But thanks! :)
How much (dosage) niacin did you start out with and did you increase over time? Can you recommend a brand? Thanks @Karla Adair
@@browneyedgirlFL67 Orthomolecular brand. 500mg about every other day for a month or two. Now I just take it here and there.
@@karlaadair6540 why did I think it needed to be taken three times a day after a meal? Did you start out at 500mg ? And when did you notice a positive change?
@@browneyedgirlFL67 it just felt powerful and like it was plenty so I just listened to my body. My tongue felt less “swollen” in about 3 days. Felt less fatigue in about 2 weeks.
Another video already? Gez, you are spoiling us 😁
Loved the painting at the end
Haha. Thanks Alison!
Awesome encapsulation and presentation of medical clinicians and researchers on the leading curve. Thank you!
Pleasure :)
With all this new info and "pieces of the puzzle" coming to light, I wonder what all this new research might mean for the study of other diseases and conditions having nothing directly to do with covid 19.
It would be nice if it sparks whole new lines of study deeper into the biochemistry and metabolic effects involved in those other diseases - and finds new answers and treatments no one knew to look for until now. If so, that would finally be something good out of covid.
I sure hope that this is useful especially for ME/CFS. It is a tough condition to live with and tolerate
I was thinking the same. In the future, Drs may look back at this time as being pivotal in understanding many debilitating health problems
@@smitakamath2008 it’s why I have been following these videos with great interest. Praying that the answer to ME will be found in this research.
I was thinking the same too. That maybe finally the healthcare industry will lean more towards a healthy lifestyle approach.
Gez, this is the first time I have added in a comment from sunny (Summertime now), South Africa. I'm 6 months in with brain fog, fatigue and chronic, constant, unbearable pain in my left leg running down from my Covid induced arthritis in my hips. On Monday I am having an MRI on my spine and hips. Thereafter, nerve conduction testing in both legs as the doctors are thinking neuropathy, and as a diabetic who was fit and reversing the type 2 condition, diabetic neuropathy. I have been so alone in my struggle with this fickle, dishonest virus and your input is greatly appreciated and I value your tireless research, in spite of the restrictions, greatly. You are my "Be the change with Covid' hero. You have cheered me up with this latest video as you are looking a tad perkier.
Thanks Anna :) I really hope you start to recover soon. I do recommend the treatments I’ve talked about in my latest films - got a study that shows they actually work coming out with my next film. Dr Wentzel is on to something!
@@RUNDMC1 thanks SO much for your helpful videos.
best of luck.
i located this protocol summary: membrane.com/world/
but am unable to locate the study results. Have you a link?
i'm taking 500 mg niacin/day, for 7 days now. still enormously fatigued.
no improvement. yet. and i still do Intermittent fasting and keto.
guess it can take months? esp if one is already NAD depleted.
thanks again!
Moiseechen yes I think it’s fair to expect recovery in the order of months rather than weeks
This is fascinating! Thank you so much for your efforts, putting this together, Gez. Hopefully , in time this regimen will bring the much - needed relief to many Long Haulers and COVID will have finally done us a favour in understanding genetic changes and damage to metabolic pathways as part of disease etiology. Cx
Thank you Carol! 😊
Thank you Gez!!! Thanks to Dr. Wentzel and his team for this gem. I wish I had this information before developing POTS. Hope that this is the answer that I have been looking for 9 months.
Hope so too! 🤞
How are you doing now?
There are millions of people worldwide, suffering for decades with post-viral illness (me/cfs). I hope that this information can also be directed to them, as they've had NO HELP so far &, in fact, have been dismissed as having psychiatric illness.
Another excellent video mate! Thanks for all your work and effort. How are you feeling these days?
Improving!
@@RUNDMC1 when did u first get the virus
Tosha Whalon March
@@RUNDMC1 have you tried fasting at all? I’ve been reading that a mixture of intermittent fasting, twined with a 3 day water fast will induce autophagy and perhaps clear out some of the virus that might still be in our bodies?!
Something of a genius Gez!
Absolutely love the interview, wish I could have been a fly on your skis - very interesting that he doesn't recommend non-flushing Niacin. Did he say why?
As always, thanks for a very clear vid!
Thanks Michelle - it’s due to the absorption and which version is best used by the body.
@@RUNDMC1 It's interesting to see the similarities. Thanks for keeping on top of this, it's helpful to so many of us.
I’m very happy to see you looking more sanguine and healthy. Wonderful.
Haha, thank you!
Gez, sorry if it's already been asked, but how are you feeling on the new regimen? Improved?
I've been ill since June, and the supplements & diet change have made an improvement over the last fortnight or so, but I still need 12+ hours of sleep.
Thanks so much for your videos and hard work over the last few months, despite your own illness -- they have been so helpful in so many ways. :-)
Yes I’m feeling better - like you still needing lots of sleep though. 9 hours is my baseline or I’m all over the shop. Glad to hear you’re improving!
I focused on Adenosine. It converts to inosine naturally in hypoxic conditions and is helped by Adenosine Deaminase but that enzyme (which is co-located with DPPIV which is a Covid receptor) is easily taken out by Covid. It is the perfect biomarker or messenger for vascular tone modulation but in the absence of Adenosine Deaminase you need to reach hypoxia for the anaerobic conversion to take place. Incidentally DPPIV also caters for (cleaves) Bradykinin and a supercomputer later suggested it could be a Bradykinin storm some months after I published my conclusions. Look up Adenosine Deaminase Deficiency and Severe Combined Immune Deficiency. We differ from other mammals in that our Adenosine Deaminase is co-located with DPPIV. Did I mention DPPIV also an Angiotensin Converting Enzyme?
Inosine helped me battle morning fatigue.
Thanks again for sharing your research! You should be nominated to Nobel!
I did not quite understand: should we take nicotinic acid for getting well?
Yes!
@@RUNDMC1 right, after 8 months maybe this nicotinic acid is the answer for me too.
after 18 months, could this be the missing peice
Niacin is a precursor, a building block that helps the body to produce NAD+. However, you can take NAD+ itself, orally, via liposomal NAD+. Liposomal NAD+ is simply NAD+ encased in a liposome capsule that protects the NAD+ from being digested in the gut and delivers it to the cells where it is needed to produce energy. Liposomal NAD+ is available on Amazon.
Hi, thank you from across the pond for these videos. They’ve given me hope and answers I’m not getting from my doctors. As evidence to support this NAD+ deficiency theory, due to ongoing symptoms 8+ months later my doctors tested my 5-HIAA levels. I had massively elevated levels, which led to a PET scan that thankfully came back normal. The most common reason for elevated 5-HIAA (a serotonin byproduct) is a carcinoid tumor. My doctors are saying my symptoms and cause of elevated 5-HIAA remain a mystery. It seems to me, however, that my test results may provide proof of the COVID affect on the NAD+ tryptophan/serotonin/IDO/5-HIAA to mast cell activation pathway theory. Curious if this tidbit helps any of the doctors with whom you’re speaking?
I’ll pass it on!
Mae B can you plz help what kind of Dr do I need to see and what questions do I ask for my long hauler symptoms? Plz help
you have to look into this doctor: he has an explanation for the serotonin-syndrome "Farid Jalali MD on twitter : ".One such platelet mediator is serotonin. Plasma serotonin is kept at tightly regulated low levels by storing 95% of body's serotonin in platelet granules
Serotonin is uniquely positioned to 𝗮𝗰𝗰𝘂𝗺𝘂𝗹𝗮𝘁𝗲 in COVID19, as it's released copiously and its reuptake is impaired....." "There is clear evidence of plasma serotonin 𝗲𝘅𝗰𝗲𝘀𝘀 in COVID19, with this excess being a result of platelet degranulation, combined with the pulmonary vasculopathy and endothelial dysfunction of COVID19, the same endothelium that is responsible for reuptake of serotonin.""It is paramount to understand the signs of serotonin toxicity, and to recognize that there is 𝗼𝘃𝗲𝗿𝗹𝗮𝗽 between ARDS / sepsis and the signs of serotonin toxicity
Distinguishing signs of serotonin toxicity include
- Myoclonus
- Hyperreflexia
- Severe agitation
- Diarrhea"and so on
@@tinrom9465 thank you so much! Very helpful. I’ll pass in to the docs.
@@erocalypse21 did you find help yet? I just came across covidlonghaulers.com Havent checked them out yet, but the vid said they would list the tests you should get and work with your GP. Wishing you all the best.
Anyone else tried getting lots of quality sleep and meditating and other forms of brain/body calming as part of your attempt to speed your recovery? I think these are forgotten ingredients in other recovery regimines.
I've been watching a lot of good videos (like this series) and reading articles and have come up with a vitamin/mineral regimine (as specified by MCAS and NAD+ research), but those only helped me get back into the incremental, very slow recovery phase (I'm in my first relapse and experienced recovery this way before) instead of a faster recovery mode. Obviously lots of good quality rest could be important to tip the Long Covid internal balance towards reestablishing our normal homeostasis. (Symptom, insomnia) But with all the extra cortisol and other inflammatory hormones and chemicals we get from both the heightened (Symptom:) anxiety caused by Long Covid and the additional stress and anxiety we are getting from out society gone mad (not to mention loss of loved ones), this could also be supporting the new homeostasis of Long covid.
Quality sleep doesn’t come easy to many of us. A symptom is still insomnia regardless of what you take. I can take melatonin and fall asleep relatively quickly but the issue is staying asleep. No amount of rest makes me feel refreshed, regardless.
This is exactly what symptoms I have experienced with Chronic Lyme Disease...along with millions more. But, the doctors don't admit we exist...I hope and pray it does not happen to the long haulers...of which I am one. Pots was a big symptom with me in the beginning...still have to sit with my feet elevated...
Have you looked into ivermectin to treat long COVID if someone has a live COVID reservoir?
I’m a recovered long hauler. Around month 6, I took a 4 day course of ivermectin. I felt a difference after 1 day and all my COVID symptoms were gone on day 2. My health has been 100% since with no further relapses.
Do you mind if I ask what your symptoms were? Brain fog??
@@evanmaxwell4649 sore throat, runny nose, body buzzing, breast pain, pain in previous recovered injury, fatigue, brain fog, shortness of breath, shoulder pain, loss of sense of smell, heightened allergies, high heart beat resembling POTS
Thank you for replying! Where did you get the ivermectin from? OTC? Online? Prescription?
@@evanmaxwell4649 I’m in Canada. I got it through the back channels. I recommend you try with your Dr first.
How to take ivermectin , I took 12 mg a day .
Single dose or double dose?
Should I take two doses in the morning and evening?
How did You take it ?
Thanks for all you do Gez! You will deserve a knighthood by the end of all of this!!! Buying the niacin now, adding it to my large collection of supplements, fingers crossed! The dietary supplements industry must be doing well this year! ;-)
Thanks Sarah - hope it does help your recovery!
Bravo! Bravo! Thank you, Gez! We are finally getting a better understanding and and encouraging news it's not likey to be permanent! I so needed confirmation on this! And tonight is Day 8 of Hanukkah... it's a Hanukkah Miracle!! 🤩
Haha, definitely!
Thank you so much. The onset of symptoms after exercise describes my experience 100%. I have always wondered why ultra-fit people seemed to be affected to such an extent. It seems counter-intuitive. I am going to start with the recommended supplements immediately.
Yes - I think ultra fit people have already been running with borderline NAD+ deficiency due to the heavy training. Makes sense with my experience too.
When you ask your body to do things, your body needs more air to be able to do it. The gas exchange in the lungs is different than when you are not doing anything. Women are more affected by men by the crap in the air because of the differences between men and women, this is why women are more likely to have systemic disfunction (autoimmunity) than men. Toxic overload.
www.amchara.com/genetics-dna/gender-differences-in-chemical-exposure
journals.physiology.org/doi/full/10.1152/jappl.1998.84.6.1872
I've got ongoing symptoms but did nothing other than moderate to light exercise after covid. I perhaps wonder if the cycle rides I did a couple of days before I displayed symptoms has caused my experience. I used to happily bike 15 miles each way for dinner in my parents garden. It knowing when I am ok to start exercising again, the last thing I want to do is set myself back.
@@RUNDMC1 can I take NAD instead of Niacin?
Many thanks for your incredible work! I think you help more people than the average doctor. I wonder if creatine could have a role in the stack? It works with ATP/energy in the cells and also makes you load up with water in the body which may be helpful. Would be great to know more about it. Looking forward to your next video.
I don’t think it would hurt - although if you’re suffering from inflammation already more water in the body may not be that helpful!
For how Long has Dr Ade Wentzel been doing his NAD+ treatment? I'm wondering since he comments on his face beein flushed from the Niacin.
Thanks again Gez, like someone else said, these videos have been more helpful than my GP.
Could I ask, are nicotinic acid, niacin and vit B3 all the same thing?
First two are the same but Vit B3 includes other forms like nicotinamide under the same umbrella (I think!)
Hi, there is a good definition here www.healthline.com/nutrition/niacin-benefits
Nicotinic acid: As a supplement, nicotinic acid is a form of niacin used to reduce cholesterol levels and lower your risk of heart disease.
Niacinamide or nicotinamide: Unlike nicotinic acid, niacinamide doesn’t lower cholesterol. However, it may help treat psoriasis and reduce your risk of non-melanoma skin cancer.
My organic chemistry is a little rusty but I think I've bought the wrong ones. I got some H&B Niacin (vitamin B3) which when reading the small print is Niacinamide based - no good according to the paper in the video. I need to get some 'pure' Nicotinic acid which I'm struggling to find. Please let me know if you locate any. Cheers : D
Tim Sweeney Amazon or eBay is probably your friend here!
Just ordered these, they are the correct type... smile.amazon.co.uk/gp/product/B00BM6QEQA/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1
Hey Gez! first off thanks for this invaluable content. You ROCK
Second, as request: Could you ask Dr Wentzel about Resveratrol? I've read some interesting things that as well as Quercetine it can promote autophagy which could be beneficial to get rid of V. presence in gut, although some studies suggest that if combined, the effect is actually reduced...
Thanks in advance mate!
I’ll try!
Wow, thanks!
Your videos help me mote than any MD I have seen. That is a very significant statement.
Thank you Max!
@@RUNDMC1 you deserve it. Well done.
Gez, you're a genius! And also a true HERO for all who are suffering this condition. A million thanks for your videos!
How do you take these supps (meal wise)? All of them at breakfast or do you divide them between three/four meals a day?
Thanks Frank! Split the niacin up over the day, same with quercetin. Others can be taken in the morning
stress release and niacin !
I have been suffering for a while now, I had an event in August which I thought was either a heart attack or a stroke. It turns out it was a stroke, I am a generally fit and healthy 30+ year old. Since being ill in March I have suffered quite badly with palpitations and dizziness. I am still under investigation at the moment.
So sorry to hear that. Best of luck in your recovery.
@@RUNDMC1 cheers :)
Nice hopeful video conclusion
Thank you so much for this informative video. Be well.
You too Leslie!
Awesome content, thank you! I've been taking Niacin for a while, MCAS symptoms improving a bit but still there.
Would adding Methylene Blue be something to consider?
Thanks
I wonder how long after recovery will we have to take niacin for? Thanks again RUN DMC 😁👍
We should be able to stagger down to a relatively low level
It would be good if you did another interview with Dr Wentzel to see how he and his patients are doing now some time has past taking his supplement stack?
I’m going to be doing a follow up study to see if the improvement is sustained. Dr Wentzel’s patients are still all doing better.
I was taking the stack via a lady in contact with Dr wentzel. She blocked and deleted me when I told her the niacin induced a depressive episode in me. The results are therefore skewed! Not taking on board people who have had negative effects from the stack.
@RUNDMC1
I can’t decipher what is being said at 9m-21s, where the discussion was a large correlation of long haulers had pre-existing conditions. One was “Rheumatoid Arthritis”, and the other was “ATP”? Not sure I understand ATP… didn’t think “ATP” was a pre-existing condition…. Maybe ATP dysfunction?
Same at 14m-05s. “Nicotinic Acid blocks the loading bay that prevents the “sump” from tryptophan to Nicotinic Acid Mononucleotide. What’s a “sump”? Can someone translate that sentence for me? Thanks! Wonderful Content.
Atopy, not ATP! (So eczema, hay fever and asthma)
@@RUNDMC1 thanks so much!
I love these videos you are doing. I appreciate all this information too.
Is it possible that the autoimmune and mast cell.could all just be a genetic mutation one have and some don't have that reacts to Covid 19. Something that can cause chronic illness's in a specific area or to a specific system that like I said Covid is re-activing to? I have eds, mcas and pots and I know there's a genetic mutation that's causing it tho they haven't found it for the hypermobile type. Do you think the real answer is in our dna with the people are are just more seasonable to chronic illness like my own?
Before Covid I had A LOT of theories when it comes to genetics and this kinda feels like i could be an over all genetic susceptibility mutation that we've just never seen before. or maybe get something we have seen over and over like those who end up with fibromyalgia and pots after getting sick with a cold or a virus period maybe there is a genetic susceptibility to these issues when the right Gene is activated by a virus?
I'd truly love to hear what anyone else has to say about this theory.
many long haulers have noticed big improvements by taking L-glutathione, and wondering if anyone can comment on if glutathione is related to the NAD+ processes that are being looked at currently?
The late Dr Konynenberg successfully treated CFS/ME patients with glutathione precursors. Maybe rectifying glutathione levels or NAD levels produces the same outcome of restoring tryptophan? 🤔
The main gap in this theory, in my opinion, is that the enzimes that are missing would eventually be produced by the body again after some time. If they aren't it means that I will have to take niacin suplements forever.
Yes the NAD+ deficiency is temporary
@@RUNDMC1 So why long haulers don't get better by themselves?!
@@RUNDMC1 So why long haulers don't get better by themselves, without any treatment? I have very mild long covid symptoms, they are mainly chills, but I cannot workout. The next few days I feel completely exhausted.
@@paulocl2 they do, from what I've gathered it takes around six months to a year for it to get back to normal levels, and it happens gradually so it might be hard to notice that it's getting better.
paulo c our best estimates are it’ll take 12-18 months in most cases
Thank you so much :)
No problem! :)
When they talk about the tachycardia symptom related to this, can I assume they mean that all of the POTS symptoms fall into that? Low blood pressure, chest pain, the palpitations and orthostatic intolerance? I’m wondering where to draw the line between NAD deficiency and actual POTS
It’s hard to know isnt it?
@@RUNDMC1 It seems so. I wish the researches would clarify that sometime soon
Thank you, Gez, for another fantastic report (I agree with those who've said you deserve official recognition for your work - and, yes, a knighthood would be appropriate :-)).
In light of this information on NAD+, I'm thinking that a combination of physical rest and reducing my stress/anxiety was key to the significant long-covid improvements I started noticing around the 5-month mark (Dr. Google confirms that stress really sabotages NAD+ levels).
I have an exercise-related question, either for you or anyone else who's inspired to answer.
I've been back to exercising since August (initial infection was March), working on returning to my pre-covid fitness level. Recently (i.e. over the past couple of weeks), I re-introduced some fairly hardcore interval training (I also had a couple of unavoidably sleep-disturbed nights). And .... wham. Moderate relapse. I'm not suffering the way I was in the summer, but I'm abnormally fatigued and dealing with some joint pain.
I've started taking niacin (just 50 mg/day for the past 3 days, but I'll be increasing - apple pectin seems to be keep the flush away). But now I'm wondering ... Should I be going back to NO exercise? I seemed to be tolerating it well before the high-intensity stuff (and bad sleeps). Or should I just avoid that stuff ... and, if so, for how long?
I'm curious about Dr. Wetzel's comment that he is now back to 3-hour windsurfing sessions, given that he is still taking niacin supplements and thus implicitly hasn't yet returned to his baseline NAD+ level.
Many thanks again!
It does seem we’ve got to be super careful with strenuous exercise in recovery.
I would take a week off completely, then start to slowly build it back in at a low level but avoid the interval training. Perhaps do a light interval session in a few weeks as a test but definitely don’t push yourself to exhaustion in that session!
@@RUNDMC1 Sounds like a plan, Stan! Thanks! When the time comes, I look forward to hearing about your fitness recovery journey. I'm thinking many of us may *not* be returning to brutal, punishing exercise programs - not because it's physically impossible but, rather, because the longterm health costs are so high.
Wow - this is a lot more than I can tolerate after 5 and a half months of Long Covid... have not been able to do any more exercise than simple walking. I used to exercise 5/6 days a week prior to L C - running, weights/gym type, ashtanga yoga - and an avid surfer. Envious that you’ve returned to some form of it already...!
Mr Jean I’m currently having a PEM attack after walking for 1.5km and daring to jog 100m of it. Seems I’m not as far along as I hoped.
@@RUNDMC1 very sorry to hear 😓. It’s hard. Also considering how seriously de-conditioned we all are. I lost about 4/5 Kg... take it easy and thank you again for this amazing work you’re doing. Just started the supplement cocktail you recommend will let you know how it goes. At first I was a bit skeptical about L-C / MCAS link precisely because of the huge list symptoms which made me think it could just claim to be the source of every illness under the sun. But these recent videos about NAD + deficiency are fascinating. If you have time I’d love to hear your thoughts about the insuline issue which I tagged you in, in another comment 😅. It does feel relevant to me... Good luck and thank you again deeply for sharing your research so eloquently.
Another great video, I really enjoy these and it seems you are using decent scientists and medical staff for the content. I have started with the supplements as suggested in your video, I'm hoping there will be a positive in terms of my reaction to these. I do have a couple of questions for you, what are your principal ailments since catching covid? How badly were you ill with your initial symptoms? and finally how has your health improved over the last few months? I do hope there is more significant improvement with your health. Thanks again for the amazing videos.
1) Brutal fatigue, headaches, cognitive issues, skin issues, palpitations, histamine intolerance, exercise intolerance
2) initial symptoms weren’t that bad - felt like a cross between a mild flu and norovirus.
3) Better the last 2-3 weeks after starting the various treatments and being more assiduous about low histamine diet.
@@RUNDMC1 I certainly share the fatigue and exercise intolerance, I suffer a lot with muscle pain and sometimes I am short of breath.
Like you my initial symptoms were flu like, the first week was dominated by fatigue, muscle ache and weakness, in the second week I became short of breath and had chest pains.
Glad to hear the treatments are working for you, I am following a similar path, I will go low histamine after Christmas. I hope your recovery continues.
Great video again, is niacin the same as vitamine B3? Since when i Google it, I will only get this (in NL) also I started low carb carb high vegetable diet and only eat on 3 moments a day, so you intestines that are a big part of the immunesystem, also get some rest during the day. For me this is starting to work. And pacing is also very important.
Yes - all very important. Yes niacin is vit b3 👍
For us folks who are unfortunate enough to fall into the POTS category, what treatments should we be exploring?
Beta blockers and Oral Hydration salts. (Brands that have the formula the WHO recommend)
Also try Low Dose Naltrexone because a friend reversed his POTS with LDN
He said most the others he was talking to online reduced their POTS too with LDN (start very very low though like 1mg and work your way up by increasing once a week, see if there’s any improvement. When you improve well that’s the dose you stay at) for some reason people seem to have a better affect than carrying on increasing the dose.
(The average LDN dose is around 3 mg to 4.5 mg)
People who rushed this medication can get very sick so you’ll see everyone saying “go low and slow”, with tiny incremental dose increases of 0.5mg. About once a week or at least 3 to 4 days of feeling okay before the next dose increase
Good luck
I wish I had this information before developing POTS :( It seems that it is going to take time 😭😭😭
@@smitakamath2008 I hear you. I wish the doctor had given some indication of how long we should expect.
I’m confused how do you what category your are in from having covid long hauler symptoms and what to ask the dr?
@@erocalypse21 it’s explained at 03:00
Hi,
Have you heard of anyone taking this stack with persistent abdominal pain, recurring fever and joint pain, improving their symptoms? 6 months of enduring with no improvements. Thank you for your much needed guidance in this difficult time.
Yes - this stack should help. I’ve got a study in my next film which is showing very good results
@@RUNDMC1 Can't wait to see it Gez, keep on the hard work, many of us rely on you!
Hi run, on your diagrams it looks like nicotinamide feeds into atp? Yet I hear what he's saying... that it has to be niacin or nicotinic acid introduced slowly... the flushing is so annoying
I’m not sure if you’ve heard of NAD IV therapy infusion. Its a type of natural treatment to boost cancer patients energy level. It’s available in the US. I wonder if this is something that we can benefit from since it goes straight to the blood.
I'm trying to get this at naturopathic clinic. It's very expensive though. Would also be a good gauge of root cause I think.
@@anthonykaralekas6275 How much can it cost a whole treatment?
@@frankttom4990 Might vary slightly on the clinic, but I think $600-1200 depending on the dose. It's insane.
I've been taking multi vitamin tablet which included 75mg of B3. Not sure if that's enough. So I just ordered a 250mg slow release B3. Will see if that's effective in a few weeks.
Good plan 👍
Thanks again Gez
Looking back, think must have been helping myself and not knowing it. I did not eat a lot of cereal. All of sudden when got Covid (In March) I kept wanting to eat it. Guess my body wanted the Vitamin D in the milk? Plus I drank "Airborne" every day. Which has many of the vitamins and zinc suggested. Now I still take a supplement of D and a vision formula vitamin. My retina's are "thinning" now. Had an issue with my wrist which think turned out to be a blood clot. That has gone away as well. Going to still take the vaccine when I qualify. Just as a booster. Was waffling on it as have had covid long term. However, it sounds like a good idea overall.
Is it possible a viral infected cell could produce viral antibodies after infecting a antibody producing immune cell? Has there been any studies(or can there be) looking into whether or not antibodies are still produced by antibody producing immune cells after becoming infected with CV19? A few different reasons reduce immune cell count to area of infection or a organ examples, a virus infecting a cell, reduced blood flow to area of infection, poor bone marrow and thymus. Immune cell deficiency also causes antibody deficiency. Antibodies bind, attach, neutralize, build and allow for communication. Immune cells are mobile antibodies are not, possibly the mobile cytokines bring the proteins to develop antibodies at the area of infection delivery could become hampered due to constricted blood flow caused by fluid and debris buildup in the lungs this could be similar for any organ.
Hi Vincent, I wouldn’t like to comment on this. The immune system is beyond complicated and this is beyond my pay grade!
@@RUNDMC1, thx for responding. Hopefully my questions could someday be helpful, my questions may be off the wall or out of the box but I think that's ok at this point to present any ideas that may lead to an educated expert to consider possibilities he may not have considered, sometimes a lot of education can lead to blinders being a long way from basics, even more now that there's is a new strain that there claiming it's more contagious and causing less severity of illness this new strain could easily mutate again and become more deadly similar to what we were hearing out of woohan at the start when people where dropping in the streets. There's no way of knowing how long the Spanish flu circulated previous to being recognized and whether or not the vaccine that was introduced at the time had any effect on herd immunity that was achieved then, in regards to mutations and variances. I firmly believe what they're calling vaccines are treatments due to the fact adaptive immunity is unproven at this time, adaptive immunity takes years to prove, I'm not against the treatments(or what they're calling vaccines) these treatments are innate system boosters and are effective, that's good, it's definitely a breakthrough in medicine and there has been a lot learned recently, there is something missing though the answer to how these start could someday be answered it may not be through the petri dish.
If covid triggered autoantibodies will it happen again with the vaccine?
We don’t know at the moment but there’s no direct evidence to suggest it will
I'm waiting to see data about the side effects of the various vaccines on autoimmune disease patients. I have Antiphospholipid Syndrome and am going to be very careful about about being vaccinated.
Gez! I don't know how else to reach you..
What are your thoughts on Ivermectin in long haulers??
See my comment and associated reply immediately following yours. Ivermectin against NF-kappaB.
Merry Christmas!!! ...from NY.
Love your videos on covid. They've given me hope. Though it's only been about 2 weeks, I feel many of the common symptoms of a long-hauler. I have some questions. Does whether you end up with long covid depend on the amount of viral load? Is recovery more likely the younger you are? Does having pre-diabetes or type 2 diabetes affect your chances of getting covid-related dysautonomia or pots? What about binge-drinking? What affect do SSRIs have, if any, on long covid? What can we do about hyperadrenergic tachycardia, insomnia, and anxiety? Thank you from California. 🙏
Hi Michael. To try and answer your questions:
1) we don’t know
2) age not a factor in recovery
3) diabetes not correlated with LC generally, can’t say for dys/POTS
4) Stop drinking immediately!
5) SSRIs seem to help seratonin levels, and thus sleep and energy generally
Really appreciate your input and advice re long covid. I share all your videos on the Irish Covid Cases group I belong to. I'm almost 9 months in now, symptoms mainly breath shortness, fatigue, heart racing. 6 months in when cardiac mri diagnosed myocarditis. Taking NAC, Ubiquinol, Zinc, VitD and multivitamin for some time now. Just started Niacin after seeing your video. My question is.. is it safe to take while on low dose beta blocker? I read that niacin can cause low blood pressure. Mine is already very low. Sorry for long post! Thank you!
Best to ask your doctor on this front - not my place to advise with potential contra-indications, sorry!
@@RUNDMC1 I understand, thanks for reply! I'll talk to my gp.
I bought a 500mg sustained release Nicotinic Acid that will prevent flushing. In your research is the sustained release ok, or is the flushing somehow necessary?
Lots of comments on this! Yes it’ll work but the flushing variety is thought to be ‘better’
Is 500 too much for 140 iOS person
Victoria McCullom I’d definitely start at a lower dose. Break the pill up into quarters and start there
Very interesting thank you , I’m starting to think normal life is over for me now , I’m working but into my 9th month of poor health and eye sight affected , dr won’t help me , not much hope anymore
Hi David. It’s hard but stay patient and do try the supplements I’ve mentioned in these films
@@RUNDMC1 thank you 🙏👍🏻
I got better from long covid after 6 months from onset of symptoms. I have a family member that works in a hospital and she came home infected. I'm now on my second stint of having covid. This time is much different. It affected my liver/spleen/gut/brain the first time. This time it's all upper respiratory. :(
So sorry to hear :(
Which were your Long Covid symptoms the first time?
Seriously what the hell is going on #Longcovid
Look into boron supplement just a 3mg daily dose could help with long covid NAD issues and more.
I have yet to see a doctor with 10% of the information that you've dug up - thanks to you and other researchers, I bring most of the knowledge to my meetings with doctors. And they charge me. Going to have to look at that... ;)
Thanks Peter! Where are you based?
Love these videos, thank you! For those of you doing this - are you taking as low a dose of Niacin as Dr Wentzel recommends? My local Holland and Barrett only had 500mg...
and experiences with flush/no-flush are appreciated too. Dr Tina Peers recommended no-flush so I bought that, but Dr Wentzel says there are side effects with this
If you don’t get the side effects then don’t worry! You can find 50mg on Amazon, but try chopping the 500s in half and just taking some of the powder, see how you get on
@@RUNDMC1 Great, thank you very much!
Hi. Great videos. Extremely helpful and hope inducing. In this video do you know if the recommended Niacin dosage of 25mg 4Xpd was per Kg body weight or is that just an adult dose?
That’s an adult dose to build up to
Has anyone had sinus inflammation sinus congestion since contracting Covid, if so what has helped??
Try boiling water, adding eucalyptus & camomile and inhaling the steam
Do sinus rinse with a neti pot. A small dot of lavender essential oil on the forehead.
yes this is my main symptom. I'm constantly inflamed. My ENT doc gave me prednisone and flonase, none of which seemed to help. She also had me to some nasal irrigation, which I almost feel made it worse, it made me feel even fuller and more pressure in my ears and sinuses. I'm at the point where I'm taking matters into my own hands now, I'm going to start these vitamins and I've changed/am changing my diet. I don't think the docs know enough yet, there def needs to be more push into research for these lingering effects. This channel is giving hope and I'm thankful and eager to start these modifications.
The doctor discusses different types of individuals, some who can recover in weeks and others in months. He uses certain terms in relation to each group. I'm dizzy, bad walking, and slowed processing of visual information. Which of those groups would I fall into? My situation was set off by heavy exercise a month after recovering from COVID.
@Tomas Muir heart beats very hard over nothing, just a bit of walking. I have to lay down a lot to get control of it.
Justin, that’s exactly what happened to me. Recovered from Covid, went back to exercise and have been floored ever since!
@@zacs5773 I lost my ability to walk for a few days. Spinal tap, MRI, lab work - nothing! The docs were clueless. I've been real sick with this for a month. I can't work or do much of anything that doesn't involve my bed. I had no idea there were so many people with similar stories.
@@scripturethroughancienteye1509 You and me both, I still have days when my legs don’t work properly. I’ve lost count of the blood tests I’ve had that say there’s nothing wrong with me. It’s been really tough for me when I used to play tennis 5 times a week and cycle 100 miles regularly. I have cycled my bike for months. I do hope these supplements work 👍🏻
@@zacs5773 Man I was in the gym everyday. I have lost twenty pounds since the onset of this post-covid thing one month ago. It seems that exercise is coming up more and more in these stories. I tried to exercise my way out of this and ended up much more sick.
If ongoing sarscov2 infection is present in small intestines , then RNA should be detectable in stool samples. That would give us some insight.
Hypothalamus..HPA axis dysfunction..do episode on that GEZ..
Yes it’s relevant!!
Is there any research on cannabis for long covid? I have a lot of esophageal pain. Low histamine and supplements are helping, but not completely.
Try CBD oil
@@RUNDMC1 thanks! I'm allergic to cbd unfortunately. I break out in hives 😫
If SARS COV2 induce persistent infection IT also induce persistent immune reaction
I recently purchased Niacin (inositol Hexanicotinate) 500mg flush free. Is this an acceptable type of Niacin or should switch it out for something else???
Better to get the flushing type but this will still help
Hi gez, thanks a lot for this research. How many months are you into long covid ? I'm a 6 monther and I have high heart rate on standing/exertion and slight brain fog which seem to persist since past two months. I'm already taking Fish oil, magnesium, b complex tablets. What's the dosage that you'd suggest for niacin ? I'd love to try that and I hope it works for me.
I’m 9 months in now, it’s no fun.
Start at 25mg niacin then build up to 4 times a day according to tolerance of flushing reaction!
@@RUNDMC1 did you have higher heart rate issues as well? If yes, did they go away at all?
Bharath Sunny Yes - definitely had the tachycardia. It’s starting to calm down a bit but I’ve got to be careful with activity as it will still spike
Lithium orotate might help with the mental issues...it does with Lyme Rages.
Gez. I salute you sir!
Thanks Edward!
Good work again I'll be getting the stack this week can you recommend if it's safe to take with pregabalin along side the stack? as fatigue and Nero issues are my main problems at rest right now thanks 😊
Ask your doctor about that, sorry!
Hey, thanks again for all your hard work and research. On the antibody tests, I like many long haulers tested negative with the Roche test. I believe it tested IGM and IGG however, I recently took a Sarsplex test and my IGA antibodies where nearly 3000, that's 3 times what is needed for a positive and that's 9 months after the initial infection. I have also learned of others getting the same results. Could there be something linked to this type of antibody? My personal feeling is, that the Virus was present in me for the first 4 months as my body invited it in for a party before realising this little bollocks was going to kill me, then decided to deal with it. I have gotten a lot better from month 5/6 however, I now feel like I am dealing with an autoimmune disorder. It's been like a disease of 2 half's, that has not finished yet. First the virus and secondly the autoimmune reaction driven by an overactive immune response and a high antibody count (only IGA) Agian, thanks for everything. In my darkest days, your research and videos give me hope. Take care.
Hi Andrew - I think a lot of us feel very similar to you, myself included. Interesting re the IgA results!
@@RUNDMC1a few people from the Bodypolitic slack group have had the same Sarsplex results with the IGA Antibodies. Most of the other antibody tests don't look at IGA, they focus on IGG and IGM only. My wife who I caught this from has the IGA and also IGM 9 months on. She had a sore throat for 2 days and no other symptoms. Typical lol.
I was pretty much using the supplements you have noted in your videos however, I also use CBD and it makes a massive difference. If I can ever help with anything, just let me know. All the best.
Andrew Bennett No worries - thanks and best of luck with your recovery!
@@andrewbennett8510 What is the main effect you notice with CBD oil? Any set of symptoms that subside? Thanks!
@@frankttom4990 hi, I still have a lot of lung burn and muscle pains around my chest and back area along with some debilitating joint pain. I also get a burning sensation in my blood and throughout my body. Dr Paul Garner described this as having chillies in the blood. This is brought on greatly by talking or doing anything physical. I find the CBD relieves this or of you can get the real oil,, it 99% removes all these symptoms. It’s unbelievable. All the best
any data on what percentage of long-haulers either were taking a prophylactic (eg HCQ, IVM) or were given early out-patient at home treatment? Thanks
Not much data on that but the figures would be very low
@@RUNDMC1 thanks, that's what I was assuming. After watching the senate hearing, I am saddened and angry over the increased devastation to Americans by the general discrediting of these treatments that could have either stopped or greatly lessened this disease in most cases.
has anyone had a NAD+ IV drip for long covid? and what were the results?