Fantastic! (Although I still struggle with how many details the parents truly want!) Thanks so much for watching and letting us know. We are planning a series of lectures on hyperbili (and role of IVIG in immune hemolysis- as that's most common place we use it). Is that what you were thinking? Or just general uses IVIG? Thanks again Vickie!
Oh yay! That makes us so happy- we wanted to use that line in the beginning- 'made ridiculously simple'-!- but as we're sure you know- it was already taken! Ha! But that's what we're aiming for every day! Thank you!!
Thank you SO much! I just started my NICU preceptorship in the NICU last week and this has made ROP so much easier to understand! Lots of love from California ❤
We love you! Thank you so much!!!! (This is a bit of a thankless task, and I guess as we grow we're getting a few more negative comments- so we can't tell you how happy your lovely words make us!!)
thank you very much for the detailed explaination. I was born 1970 (Vienna, Austria, Europe) and at that time there was unfortunately no standardized retina screening in premature babys. i was a 6 month baby with about 900g of birth weight und do suppose the medical staff had to fight for my life. they say i was in the incubator for approx 4 weeks and a total of 3 months in hospital. Developed almost all the stages of ROP (which at that time had i different name "retrolental fibroplasia"); in early childhood i do remember having eye sight in both eyes because i found it funny to squint on purpose. at about the age of 5 i developed a severe cateract on the right eye almost overnight and from that moment on they could no longer see the retina and made no mor echography, finally i lost total eye sight there, due to neo-vascularisation. on the left eye up to date i have remaining eye sight of about 1% and go to check up regularily and until now what remains of the retina there, is stable. i did also develop cateract here and since 1991 i have an artificial lense and still a slightly translucent capsule and "things floating around" in the vitrious, they did offer me some laser treatment to get rid of the rest of the capsule enclosing the lense but i find it for the moment too risky. as long as my eye sight stays like it is, i am somewhat content. IT IS NICE TO HEAR that today babys are well screened to prevent blindness or loss of eyesight. again tnx for the video. greetings from Vienna! (Roland Schweiger)
WOW that is such an amazing story! It is absolutely crazy how much everything has changed- but it is super strong babies like yourself who survived with an excellent outcome who showed the world whats going with the eyes. Thank you so much for sharing it. Would you be OK if I alluded to it in future talks? Thanks so much for watching our video and for taking the time to write!!!!
As always, brilliantly presented. I was at this year's PAS in Washington DC and saw you in person when you went to the mic to ask question on one of the sessions; though didn't come to say hi, it was good to see you. Love and enjoy your videos! You're a natural educator👏👏👏. Also I have enjoyed your interview on The incubator Podcast.
What a lovely comment! Thank you so much! Except I wish you came up and said hi! Next conference we see each other!!!! And thanks for listening to the interview- I felt I rambled a lot- and also felt weird to be talking about something I don't really feel like I'm in expert in- having done it for like 3 years!!! Anyway- thank you again- so much for being here :)
You have explained this the best out of any video I've found. I was born at 25 weeks and had ROP - I had surgery and now am only nearsighted fortunately, but wanted to understand what ROP is. Thank you!
Hi Molly! Love hearing from ex-preemies- thank you! About ten years ago, I rounded with a medical student who told me she had surgery for ROP too, and I was so impressed she didn't even need glasses. She looked at me like I was a 100 years old and said, "I'm wearing contacts." So glad you're doing so well now, and that this video helped :)
Professor Khalid . Dr Tala ,Really appreciate your style and way of presentation. You have a knack of simplifying most difficult stuff into ridiculously easy to understand. Keep going.Wish you the best.
Thank you so much! High frequency will follow the jaundice talks- in a couple of weeks. TORCH is on our list too!!! Thanks so much for watching and for your suggestions.
Stage 0 means the vessels are developing exactly as they would be in utero (ie nice and flat). The zones are larger concentric circles around the eye- zone 1 being smallest with macula in it. Zone 3 means nearly fully vascularised. That’s why we worry a lot more about zone 1 than zone 3
Hello Sydney- great question- it is thought to be related to the effect of Oxygen on vascular endothelial growth factor (remember avastin targets this). High or low Oxygen at critical periods may up or down regulate this protein. I'm not sure beyond this!!!
Wonderfully explained! Thank you for another great video! So you said for normal blood vessel growth in utero they should grow flat vs the blood vessels in premature eyes grow forward into the vitreous humor. I’m wondering what that looks like flat vs forward on an eye diagram. Also are the normal blood vessels only supposed to grow to a certain area in the eye and when they move into the vitreous humor area then that’s a problem? Also how does the greater number of blood vessels pull the retina off the back of the eye? Is it because they clump together?
Hello! There aren't really signs ROP- by looking at the baby- we can't tell what stage or zone the retinal vessels are at (which is why the ophthalmologist needs to dilute the eyes and look directly at the retina).If the ROP reached the stage of detachment- which obviously should never happen-the infant would lose his red reflex.
Hello! Thanks so much for your lovely words. There are a couple of videos we have already filmed and we are releasing soon- but BPD is the next to be filmed. Thanks so much for being here :)
Hi Griffin! thanks SO much for your lovely comment! And a general lecture on pharmacology is a BRILLIANT idea- we did not have that on our list.So thank you so much!
Hello Shayaan- not sure how we missed this lovely comment! But thank you so much for the positive reinforcement- when it gets busy in our lives, it's the only thing that keeps us going!!! So thank you so much!!!
Hello! Excellent question! You can have much worse ROP in one eye compared to the other. (This is less likely because obviously the infant has the same genes and has been exposed to the same environment). Usually if there is a difference, it is only one stage difference between the eyes. (Which may sometimes mean one eye needs treatment but the other doesn't). Thank you
My Nephew was born pre-mature and was admitted to NICU for 3 days, he survived but later was diagnosed with Stage 5 ROP, the doctors suggested us that there is no cure for it now as both eyes dont have light
Yes! These are the next few videos: HFOV, BPD, NEC, hydrops, and starting the series on fluids and electrolytes. We're getting there, we promise!!! Thanks for watching and commenting :)
Great question. Normally we use corrected gestational age (or cGA) to refer to the baby's age as if the baby were still in utero. So a an ex-28 week preemie who is now 4 weeks old, has a corrected gestational age of 32 weeks. When ex premies are older, we use it similarly, to evaluate developmental milestones. So for example for a baby who was born at 24 weeks GA (40-24= 16 weeks. 16 weeks ~ 4 months early) who just turned 12 months old, we would say his corrected age is 8 months. So even though technically the baby is one, we would expect him to have the developmental milestones of an 8 month old. We stop accounting for the prematurity of babies when they reach 3 years old. Hope this helps!!!
Oh wow/ I’m so sorry for all the surgeries you’ve had- I hope you have reasonable vision now. You hit the point exactly/ more important to save a life than save full vision- so I’m sure your medical team did what they had to do. Wishing you health!
Hi! I had 31 week prem twins 1.5 years ago, I have a Hosptial eye routine appt coming up. Will they be testing for ROP again this time?- already had twice since being born and nothing found. Or is this likely just to be a standard eye test. Unable to get through to the Hosptial for info
hello- congratulations on your twins! The eyes at this point would be fully vascularized (i.e. the blood vessels are fully developed at the back of the eyes)- so not really checking for ROP. BUT- babies born earlier are at risk of having other eye issues- like short-sightendness- so they're likely following up with this. Good luck!!
Excessive Oxygen Exposure in the Preterm neonatal period is a major factor in capilary atrophy and can lead to ROP. But One though I have was: If a Pregnant woman was kept in a state of Hyperbaria for the the last 3-4m of pregnancy then could this have a similar effect on retinal vascular growth and at birth when Oxygen blood levels drop suddenly, could vascular overgrowth like ROP occur?
I have struggggeled with ROP and finally feel confident in explaining it simply. THANK YOU. Could you do one on IVIG?
Fantastic! (Although I still struggle with how many details the parents truly want!) Thanks so much for watching and letting us know. We are planning a series of lectures on hyperbili (and role of IVIG in immune hemolysis- as that's most common place we use it). Is that what you were thinking? Or just general uses IVIG? Thanks again Vickie!
Fantastic lecture. I am a proud student of these lectures now. You made it ridiculously simple Dr. Tala.
Oh yay! That makes us so happy- we wanted to use that line in the beginning- 'made ridiculously simple'-!- but as we're sure you know- it was already taken! Ha! But that's what we're aiming for every day! Thank you!!
Thank you SO much! I just started my NICU preceptorship in the NICU last week and this has made ROP so much easier to understand! Lots of love from California ❤
Oh yay Trisha! Congrats on your new role!!! You’re in the best place in medicine :) thanks for taking the time to write to us!!!
This was great! Straight to the point, short and simple. Easy to understand and follow. Thanks again, Dr. Tala!
We love you! Thank you so much!!!! (This is a bit of a thankless task, and I guess as we grow we're getting a few more negative comments- so we can't tell you how happy your lovely words make us!!)
thank you very much for the detailed explaination. I was born 1970 (Vienna, Austria, Europe) and at that time there was unfortunately no standardized retina screening in premature babys. i was a 6 month baby with about 900g of birth weight und do suppose the medical staff had to fight for my life. they say i was in the incubator for approx 4 weeks and a total of 3 months in hospital. Developed almost all the stages of ROP (which at that time had i different name "retrolental fibroplasia"); in early childhood i do remember having eye sight in both eyes because i found it funny to squint on purpose. at about the age of 5 i developed a severe cateract on the right eye almost overnight and from that moment on they could no longer see the retina and made no mor echography, finally i lost total eye sight there, due to neo-vascularisation. on the left eye up to date i have remaining eye sight of about 1% and go to check up regularily and until now what remains of the retina there, is stable. i did also develop cateract here and since 1991 i have an artificial lense and still a slightly translucent capsule and "things floating around" in the vitrious, they did offer me some laser treatment to get rid of the rest of the capsule enclosing the lense but i find it for the moment too risky. as long as my eye sight stays like it is, i am somewhat content.
IT IS NICE TO HEAR that today babys are well screened to prevent blindness or loss of eyesight. again tnx for the video. greetings from Vienna! (Roland Schweiger)
WOW that is such an amazing story! It is absolutely crazy how much everything has changed- but it is super strong babies like yourself who survived with an excellent outcome who showed the world whats going with the eyes. Thank you so much for sharing it. Would you be OK if I alluded to it in future talks? Thanks so much for watching our video and for taking the time to write!!!!
As always, brilliantly presented. I was at this year's PAS in Washington DC and saw you in person when you went to the mic to ask question on one of the sessions; though didn't come to say hi, it was good to see you. Love and enjoy your videos! You're a natural educator👏👏👏. Also I have enjoyed your interview on The incubator Podcast.
What a lovely comment! Thank you so much! Except I wish you came up and said hi! Next conference we see each other!!!! And thanks for listening to the interview- I felt I rambled a lot- and also felt weird to be talking about something I don't really feel like I'm in expert in- having done it for like 3 years!!! Anyway- thank you again- so much for being here :)
You have explained this the best out of any video I've found. I was born at 25 weeks and had ROP - I had surgery and now am only nearsighted fortunately, but wanted to understand what ROP is. Thank you!
Hi Molly! Love hearing from ex-preemies- thank you! About ten years ago, I rounded with a medical student who told me she had surgery for ROP too, and I was so impressed she didn't even need glasses. She looked at me like I was a 100 years old and said, "I'm wearing contacts."
So glad you're doing so well now, and that this video helped :)
Professor Khalid .
Dr Tala ,Really appreciate your style and way of presentation. You have a knack of simplifying most difficult stuff into ridiculously easy to understand.
Keep going.Wish you the best.
Thank YOU so much Professor Khalid. It's literally exactly what we're trying to do, so we really appreciate the time you took to write to us :)
Excellently presented! Thank a lot again!
Thank you so much Dr. Asefa- glad you're still watching these :)
Really fantastic and easy way to understand ROP
Thank you so much Hany- for watching and for taking the time to comment!
Thank you. Your lectures are helping me in my nursing program.
Thank you for letting us know- so happy that they're helping you at all :) Good luck with your training!
Your talks are very interesting , please do a talk about TORCH infection and high frequency ventilation... thanks
Thank you so much! High frequency will follow the jaundice talks- in a couple of weeks. TORCH is on our list too!!! Thanks so much for watching and for your suggestions.
awesome, very simple and easy to understand.
So glad you think so- thanks so much for letting us know :)
perfect and comprehensive explanation, many thanks
Thank you so much for taking the time to comment (and for subscribing!)
thank you for your detailed explanation. you are amazing
Thank you so much for watching Mahasti, and for taking the time to comment! We appreciate you :)
Thank u so much for the class ❤
You're welcome 😊
simply beautiful!
Thank you so much!!
Thanks for the great info!! My question is, what does stage 0 zone 1/2/3 mean?
Stage 0 means the vessels are developing exactly as they would be in utero (ie nice and flat). The zones are larger concentric circles around the eye- zone 1 being smallest with macula in it. Zone 3 means nearly fully vascularised. That’s why we worry a lot more about zone 1 than zone 3
Thanks that is such a simple and easily understandable talk
That is exactly our goal- thank you so much for letting us know :)
Great talk! This is was so helpful for my NICU rotation
Oh we're so glad! Thanks so much for letting us know!!!
Awesome! Can you let us know why prolonged oxygen therapy can effect ROP? Thanks!
Hello Sydney- great question- it is thought to be related to the effect of Oxygen on vascular endothelial growth factor (remember avastin targets this). High or low Oxygen at critical periods may up or down regulate this protein. I'm not sure beyond this!!!
I love hearing your lessons!
Thank you so much Mari- for still being here and for still taking the time to write to us!
Thank you ❤❤❤
You're welcome 😊
Wonderfully explained! Thank you for another great video! So you said for normal blood vessel growth in utero they should grow flat vs the blood vessels in premature eyes grow forward into the vitreous humor. I’m wondering what that looks like flat vs forward on an eye diagram. Also are the normal blood vessels only supposed to grow to a certain area in the eye and when they move into the vitreous humor area then that’s a problem? Also how does the greater number of blood vessels pull the retina off the back of the eye? Is it because they clump together?
Hi! Sorry took so long! maybe watch this video: may explain it better: ruclips.net/video/OyaUpwSYe0w/видео.htmlsi=i1AKstyL1MZLgDqE
See if that helps!
Thank you so much, very informative!
So glad it was helpful- thanks for taking the time to comment :)
Nice video and explanation
Thank you so much Sumathy- for watching and commenting.
Excellent
Thanks so much Muhammad!
Can you tell symptoms and there resions ?
Hello! There aren't really signs ROP- by looking at the baby- we can't tell what stage or zone the retinal vessels are at (which is why the ophthalmologist needs to dilute the eyes and look directly at the retina).If the ROP reached the stage of detachment- which obviously should never happen-the infant would lose his red reflex.
Wondering if you can do “presenting your baby during rounds”
That's a good idea- do you mean from a nursing or med student or resident perspective?
@@TalaTalksNICU Nursing perspective. Thank you, looking forward for that video.
@@TalaTalksNICU from a resident perspective
@@TalaTalksNICU Nursing perspective pls
@@TalaTalksNICU From a med student's perspective.
Amazing abstract. Could you give us a summary of BPD, please?
Hello! Thanks so much for your lovely words. There are a couple of videos we have already filmed and we are releasing soon- but BPD is the next to be filmed. Thanks so much for being here :)
Thanks for the information ...
Thank you so much for watching!
Amazing learning experience
Thanks
Consider neonatal pharmacology as the next topic
Hi Griffin! thanks SO much for your lovely comment! And a general lecture on pharmacology is a BRILLIANT idea- we did not have that on our list.So thank you so much!
@@TalaTalksNICU thanks from Kenya we're getting enlightened
amazingly detailed , thanks a lot
Thank you Emily for watching. We are getting to pulmonary edema!
NICU Tala Talks 🤭🤭🥰🥰🥰🥰🥰 sooo excited😍😍😍
Keep going.Wish you the best.😁
Hello Shayaan- not sure how we missed this lovely comment! But thank you so much for the positive reinforcement- when it gets busy in our lives, it's the only thing that keeps us going!!! So thank you so much!!!
Thank you mam
Thank you for watching!
Can it be rop in one eye
Hello! Excellent question! You can have much worse ROP in one eye compared to the other. (This is less likely because obviously the infant has the same genes and has been exposed to the same environment). Usually if there is a difference, it is only one stage difference between the eyes. (Which may sometimes mean one eye needs treatment but the other doesn't). Thank you
@@TalaTalksNICU its in my situation so.
My Nephew was born pre-mature and was admitted to NICU for 3 days, he survived but later was diagnosed with Stage 5 ROP, the doctors suggested us that there is no cure for it now as both eyes dont have light
Would there be any chance to get his vision restored? He is around 5 1/2 Months old now.
Im so sorry about your nephew. This sounds very unusual- and definitely a question for an ophthalmologist. I wish you luck.
He born at which week??
Can you please make a video on necrotizing enterocolotis
Yes! These are the next few videos: HFOV, BPD, NEC, hydrops, and starting the series on fluids and electrolytes. We're getting there, we promise!!! Thanks for watching and commenting :)
What does it mean by corrected age?
Great question. Normally we use corrected gestational age (or cGA) to refer to the baby's age as if the baby were still in utero. So a an ex-28 week preemie who is now 4 weeks old, has a corrected gestational age of 32 weeks.
When ex premies are older, we use it similarly, to evaluate developmental milestones. So for example for a baby who was born at 24 weeks GA (40-24= 16 weeks. 16 weeks ~ 4 months early) who just turned 12 months old, we would say his corrected age is 8 months. So even though technically the baby is one, we would expect him to have the developmental milestones of an 8 month old. We stop accounting for the prematurity of babies when they reach 3 years old. Hope this helps!!!
@@TalaTalksNICU Ah! Thank you so much, that explanation helped!
I am y0 hears old and have ROP. I had many surgeries for retinal detachments…. I wasgiven oxygen to save my life.
Oh wow/ I’m so sorry for all the surgeries you’ve had- I hope you have reasonable vision now. You hit the point exactly/ more important to save a life than save full vision- so I’m sure your medical team did what they had to do. Wishing you health!
Hi! I had 31 week prem twins 1.5 years ago, I have a Hosptial eye routine appt coming up. Will they be testing for ROP again this time?- already had twice since being born and nothing found. Or is this likely just to be a standard eye test. Unable to get through to the Hosptial for info
hello- congratulations on your twins! The eyes at this point would be fully vascularized (i.e. the blood vessels are fully developed at the back of the eyes)- so not really checking for ROP. BUT- babies born earlier are at risk of having other eye issues- like short-sightendness- so they're likely following up with this. Good luck!!
Excessive Oxygen Exposure in the Preterm neonatal period is a major factor in capilary atrophy and can lead to ROP. But One though I have was: If a Pregnant woman was kept in a state of Hyperbaria for the the last 3-4m of pregnancy then could this have a similar effect on retinal vascular growth and at birth when Oxygen blood levels drop suddenly, could vascular overgrowth like ROP occur?
That's a great question! I don't know! Logically, I would expect it to though!
I have rop slightly
From prematurity? Hope your vision is OK now!?