Depression Therapy An Overview

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  • Опубликовано: 11 апр 2021
  • Deciding an appropriate therapy for depression continues as the subject of debate. Certainly if an underlying medical disorder or a medication causes the depression, the immediate course of action appears straightforward. Hypothyroidism, HIV, beta blockers, cardiac medicines and drugs meant to treat psychiatric disease represent examples of the association.
    Arguments exist about when to employ non-medicine treatments for depression such as cognitive behavioral therapy versus more traditional antidepressant drugs. Some studies demonstrate very little if any difference in response between these therapies. However the benefits of CBT continue long after the 6-8 sessions while antidepressants provide relief only during ongoing therapy.
    Evolving concerns suggest too many individuals receive inappropriate prescriptions for antidepressants. In England and Australia preferred therapy formild to moderate depression avoids use of oral medicines. Studies now suggest only minimal differences between antidepressants and inactive placebo therapy for these patients.
    Although heralded as directed therapy for depression, the newer drugs including the SSRIs - Prozac, Paxil, Zoloft, Celexa, Lexapro - and the SNRIs - Effexor, Cymbalta - may not provide the anticipated relief. Worse yet, the side effects may be considerably greater than anticipated and dwarf any improvement in symptoms.
    Alternative therapies for depression include ketamine, modafinil, thyroid replacement, methylphenidate, light therapy and transcranial magnetic stimulation. None of these is firmly entrenched in our armamentarium.

Комментарии • 86

  • @lordviksta
    @lordviksta 3 года назад +13

    Dr. Landow is very knowledgeable about this subject specially considering that he specializes in dermatology.

  • @geopolitik1016
    @geopolitik1016 3 года назад +16

    Thank you for talking about MAOIs. A real doctor is one who understands that MAOIs (and TCAs) are the most effective medicine! MAOIs need to be brought back into popularity. Depression is no joke and needs serious treatment.

    • @sidka8435
      @sidka8435 3 года назад +1

      I guess for example mixing SSRi+NDRi would be the same as MAOis .Just like for example escitolapram+amphetamine. MAOIs were SNDRi antidepressants at least.

    • @ianmacaig2696
      @ianmacaig2696 2 года назад +1

      @@sidka8435 this is sorta true but loses nuance. The action of MAOIs isn't the same as SSRI + amphetamine. MAOIs stop the breakdown in neurons of all monoamines, including phenethylamine and melatonin. MAO is in the synapse, so inhibition means more neurotransmitter is able to be repackaged into synaptic vesicles and be reused, helping firing. SSRIs stop reuptake into the synapse, so neurons receive signals better. Amphetamine has yet another unique action, functioning to release dopamine and norepinephrine directly from vesicles into the presynaptic cleft in a variety of ways. So while both of these options result in increases in serotonin, dopamine, and norepinephrine, the MAOI also increases phenethylamine and melatonin, and doesn't function as a releasing agent.

    • @sidka8435
      @sidka8435 2 года назад

      @@ianmacaig2696 ++ great explanation,thx

    • @ev1ilfreak
      @ev1ilfreak 2 года назад

      @@sidka8435 i use escitalopram and abuse street amphetamine sulphate. What is the end result ?

    • @sidka8435
      @sidka8435 2 года назад

      @@ev1ilfreak what i ve heard some american psychiatrists-probably only few- use combinations like this one-escitolapram+Ritalin,Adderall for depression.Just don t use methamphetamine instead of amphetamine sulphate No reason to use meth when You have amph...Maybe ask for combination escitolapram+bupropion,it s safer and legal

  • @garysimone4977
    @garysimone4977 2 года назад +5

    Listening to the good doctor several vids I get tbe feeling he is anti drug .... good for him

  • @evanrudibaugh8772
    @evanrudibaugh8772 2 года назад +6

    I wish my depression were more episodic. I would love it if I just had an occasional six-month period of darkness.
    (It's also a little ironic that the nature of the anti-depressant industry is quite depressing. Relatively few people see improvement. The improvement is generally small, and the side effects can be disturbing. However, the funding promotes the opposite story.)

  • @tdang9528
    @tdang9528 11 месяцев назад +1

    He talks in a way that a good experienced doctor should. Gives you the full picture and unbiased and objectivity scientific but accessibile to patients and general lay person. Sometimes I feel that my mechanic is better at helping me than most doctors, not for their lack of expertise but it just seems many arent good with how to address problems in getting to root causes and most practical ways of helping and fixing, this is something mechanics are good at.

  • @jesuslopez7274
    @jesuslopez7274 3 года назад +2

    Amazing video!!

  • @dariusashouri2439
    @dariusashouri2439 3 года назад +1

    Thankks Doc

  • @f12025
    @f12025 3 года назад +2

    Please make an exclusive video on IBS D

  • @marymcwatters7606
    @marymcwatters7606 2 года назад +6

    Gardening helps my chronic depression, and tinnitus when I feel weak I eat tuna fish and it gets me up. I don't think it ever goes away, but talking, having friends, exercise always helps.

    • @mazrimazri6101
      @mazrimazri6101 Год назад +1

      Describe your depression what do u feel

    • @BigDaddyBostin
      @BigDaddyBostin Год назад +2

      Tinnitus gives depression....

    • @ioannisstermougkou8015
      @ioannisstermougkou8015 Год назад

      @@BigDaddyBostin do you know the best way for tinnitus to stop ?

    • @BigDaddyBostin
      @BigDaddyBostin Год назад

      @@ioannisstermougkou8015 probly blood pressure go to the doctor lol I wouldn't know gl

    • @blancacasillas8226
      @blancacasillas8226 Год назад

      Mary I am also going through the same thing, can I get your contact info? Do you take any antidepressants or supplements for depression?

  • @sunset33533
    @sunset33533 3 года назад +6

    The mindfulness book "30 Days to Reduce Depression" by Harper Daniels has really good exercises to relieve depression.

    • @jawadarabic
      @jawadarabic 3 года назад

      ruclips.net/video/7d16CpWp-ok/видео.html

    • @svalentina3075
      @svalentina3075 3 года назад

      unfortunately my library doesn't carry that - and they carry everything

  • @hcotyler
    @hcotyler 3 года назад +3

    Please do one on TMS

  • @iKam1Kaz1
    @iKam1Kaz1 3 года назад +2

    Great video. Have you made one about keppra yet?

    • @jawadarabic
      @jawadarabic 3 года назад

      ruclips.net/video/7d16CpWp-ok/видео.html

  • @dbp192000
    @dbp192000 3 года назад

    I need guidance on Chronic EBV. My doctors are clueless on how to treat or even approach my chronic mono , which I've tested positive for on 5 different occasions. I've had a negative PCR test but Early Antigen has been positive many times and my health is deteriorating

  • @wenus4391
    @wenus4391 3 года назад +4

    Need a video about schizoid personality disorder

  • @DonzLockz
    @DonzLockz 2 года назад +4

    You are a walking encyclopaedia! I had it since I was about 5 or 6 but it was formerly diagnosed and medicated at 34 years old. I'm 54 and have tried probably all meds with mediocre results. I also have GAD and social phobia. I'm looking for a miracle now. :/

  • @jamie1081
    @jamie1081 3 года назад +7

    I have tried over 20 medications with minimal benefits.
    I am treatment resistant.
    ECT didn’t help.
    Psychotherapy doesn’t do anything. :/
    Ketamine next!

    • @philipj8402
      @philipj8402 3 года назад +4

      i never comment on youtube ever, but i tried 16 meds, tms, ect, cbt, emdr.....the works. Esketamine, called Spravato, was my last option and it worked. The first and only treatment to do so.
      You still have options too, VNS has been getting really positive responses in clinical trials, as well as psilocybin. There are great videos on all three, esketamine, vns, and psilocybin on youtube.
      I am so sorry that you have this terrible terrible disease. I really hope you find relief.

    • @ClareSw
      @ClareSw 2 года назад +1

      I tried almost all.. combos too. Now on Brintellix I was so deep down it helped me to move out from bed 2 years ago but I'm in my bed again absolute zero interest

    • @muiresuilgorm3452
      @muiresuilgorm3452 Год назад

      @@ClareSw How are you now?

  • @Deetrim
    @Deetrim 3 года назад

    Please do one on OCPD

  • @tshephangmoswete1286
    @tshephangmoswete1286 3 года назад +1

    I was prescribed epilim before the seroquel by a GP which gave me many unpleasant side effects as well including sweet smelling urine. I have diabetes in my family so I stopped it after about a week.

  • @robertb.3651
    @robertb.3651 3 года назад +1

    Check out Peter Breggin MD on these subject too folks !!!!

  • @dailydoseofmedicinee
    @dailydoseofmedicinee 3 года назад +1

    👏👏

  • @dariusashouri2439
    @dariusashouri2439 3 года назад +2

    “Atlas of visible human male” its book behind the doctor , look like an interesting book!

  • @janisjansons5707
    @janisjansons5707 3 года назад

    Do a video on Telmisartan

  • @sidka8435
    @sidka8435 3 года назад

    Doctor,please do a video about Methadone

    • @jawadarabic
      @jawadarabic 3 года назад

      ruclips.net/video/7d16CpWp-ok/видео.html

    • @sidka8435
      @sidka8435 3 года назад +1

      @@jawadarabic thanx,we don thave mosque or islamic centre here where i live

  • @jamie1081
    @jamie1081 2 года назад

    Please do Selegiline

    • @Tom-fo5ce
      @Tom-fo5ce Год назад

      I used it. It worked when nothing else did. I am also considering magnetic therapy. A good guy on YT is Robert McMullen. He has very stubborn depression and has many years treating it successfully.

  • @garysimone4977
    @garysimone4977 2 года назад +5

    Wait this guy is a dermatologist

  • @stringedassassin
    @stringedassassin 2 года назад +1

    4 episodes a lifetime... Who are those people?

  • @uumrami3081
    @uumrami3081 3 года назад

    Trick move or change your environment

  • @tshephangmoswete1286
    @tshephangmoswete1286 3 года назад +6

    I would rather be depressed than give my soul to these drugs 😞

    • @jawadarabic
      @jawadarabic 3 года назад

      ruclips.net/video/7d16CpWp-ok/видео.html

    • @anamouchette5588
      @anamouchette5588 3 года назад +13

      depression will take your soul first

  • @AliAli-uy3tc
    @AliAli-uy3tc 2 года назад +1

    Like like like like

  • @janisjansons5707
    @janisjansons5707 3 года назад +1

    I think is Lifestyle,You are just not doing something right whit your body or your Life.

    • @jamie1081
      @jamie1081 2 года назад

      Wrong

    • @reggiepalmer6157
      @reggiepalmer6157 2 года назад

      I'm sure that's part of it the way the constructive Society is it really sucks and it's very depressing

  • @alanc9068
    @alanc9068 2 года назад

    THE DOCTOR IS A DERMATOLOGIST

  • @sabrinamcalister200
    @sabrinamcalister200 Год назад

    Meeting Dr Igudia RUclips channel was the beginning of a new life for me after using his herbs medication in curing my Genital herpes Virus

  • @iknowthisone6844
    @iknowthisone6844 Год назад

    docs is useless. i fix me self

  • @harness84_29
    @harness84_29 2 года назад

    the best therapy for depression is cardio and vitamin D. Wake up and get your ass outside, get your ass out there!! make a playlist and get on that treadmill. seroquel is the devil. it will make you fat and lazy as phuck

  • @sevenman9672
    @sevenman9672 3 года назад +1

    Pregabalin and kratom

  • @lordviksta
    @lordviksta 3 года назад

    I wish he didn’t sound like Tucker Carlson

  • @kaistun
    @kaistun 2 года назад

    /oo Doctor Landow I got a hard depression 4 years ago in 2018 in the city of Cassel in Germany.
    The depression was so hard that it affected my brain understanding.
    /oo I lost my job, lost my mariage and took the next flight to my home country Tunisia. /oo I got those terrible nightware and less light and vitamine D in Germany.
    /oo since 2020 I build a new life and was working in the pharmacy of my father in Tunisia.
    /oo my question does Olanzapin help as a medical treatement /oo or should I take Deroxat (paroxat).
    /oo anyway what I know is until today depression is less understood.
    /oo what I can say that depression distroyed my life in Germany. I was a computer scientist and happy married man. But one day depression heavly affected my life and I had no life insurance against it.
    /oo today, a had another life but I am happy in my home country and I had no nightware so I sleep well.

    • @ioannisstermougkou8015
      @ioannisstermougkou8015 Год назад

      I’m very glad to hear do you take OLANZAPINE along or with something else