53. Leigh syndrome; mitochondrial. DD acute necrotising encephalitis (ANE), Japanese encephalitis

www.brainbitbybit.com/index-info
At 5 minutes I show 2 different patients with Leigh syndrome and their MRIs saying "it is reversible". instead of "It can be reversible".
‪@brain-bitbybit2009‬
#mitochondrialdisease #neuroradiology

[@Hayet-jb2sd]

What's the pronostic and what's the traitement

[@brain-bitbybit2009]

Thanks for watching.
Leigh is a heterogenous disease, so prognosis differs and treatment should be tailored to the underlying mutation/defect. If this is a personal question, your own doctor or specialist in the region where you live can help, explain and inform you.
In general this website is useful for MDs and patients: www.ninds.nih.gov/ with a section on Leigh syndrome and treatment.
For MDs: There was an interesting article in Neuropediatrics 2014 with review of long term survivors DOI: 10.1055/s-0034-1383823

[@marwajon3891]

Моя дочь скончалась от Синдрома Лея митохондриального заболевания , мутация NDUFA13 … к сожалению , лечения до сих пор нет ….

[@brain-bitbybit2009]

I used google translate to read your message: My condolences for your daughter.
There are many diseases that are labelled rare, without a cure and that is very difficult for patients and loved ones. I hope that explaining the mechanisms of all diseases, common and rare, increases the "general" knowledge of how the brain works. I hope that by lifting our level of knowledge the rare diseases reciprocally benefit as well. So that people with rare diseases feel less unseen.
Wishing you all the best.