Pedigree Analysis methods - dominant, recessive and x linked pedigree

Pedigree analysis by suman bhattacharjee - This lecture explains about the different rules of pedigree analysis. It explains how to find a pedigree based on characteristics with examples as dominant pedigree, recessive pedigree and x linked pedigree.
Dominant inheritance - affect shown in every generation
recessive inheritance - skips generation
X linked recessive trait - Male offspring are affected more.
For more information, log on to-
www.shomusbiology.com/
Get Shomu's Biology DVD set here-
www.shomusbiology.com/dvd-store/
Download the study materials here-
shomusbiology.com/bio-material...
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in RUclips. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services - www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam - www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
Our Website - www.shomusbiology.com
Facebook page- / shomusbiology
Twitter - / shomusbiology
SlideShare- www.slideshare.net/shomusbiology
Google plus- plus.google.com/1136485849827...
LinkedIn - / suman-bhattacharjee-2a...
RUclips- / thefunsuman
Thank you for watching

[@nabeelmusa722]

Attention please.
Pedigree no 3 can be both x-linked recessive or autosomal recessive..
Very important to look again and again ..
Both possibilities are applicable..

[@pranjalkumar7693]

Yes there is no any probability of x linked pass father to son but there is also a probability is that trait comes from mother...

[@KJKP]

At 15:55, Shomu says that, in X-linked recessive pedigrees, the trait NEVER transfers from father to son.

[@enoch9019]

Both can apply here

[@enoch9019]

@@KJKP but if both parents are affected, then the daughter is getting it from the affected father and the son is getting it from affected mother.

[@liteducks]

Because both father and mother are affected in the second generation, it is hard to discern whether the sons received the trait from mom or dad therefore allowing both autosomal recessive and x linked to be possible

[@elisabethnoe5952]

I see you have professionalized your introduction. LOVE IT! I have been watching your videos for some time and am impressed with the direct, concise and thorough approach you take in your presentations. Your hard work is greatly appreciated and well loved by many students. Come visit MacEwan University Edmonton Canada!

[@shomusbiologyofficial]

+Elisabeth noe thank you. It's a pleasure to help you out.

[@bightonchinembiri]

two semester now gone, you have always been a life saver, keep up with the good work, brilliant videos there

[@zainabqureshi9178]

Hey

[@stavshmueli6932]

For the third question, from the diagram you can deduce that it's either x-linked recessive or autosomal recessive. It's unsure which one of the two is correct though, need more information.
Additionally, for the fourth question, it doesn't have to be x-dominant, there're other inheritance patterns that fit that pattern...

[@Helloomi97]

i also got that and i was so confused when he said it couldn't be x-linked recessive..

[@roshansharma2309]

You are the first person who explain logic behind the topic

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@over-pronouncedmayonaise3464]

@@shomusbiologyofficial Yes!

[@Sona-yf4cl]

Thank you so much sirr😍😍 from the past 3 -4 days I'm trying to understand pedigree but now at the time only I can understand the concept clearly with some golden rules .Now I can gain some extra marks in exam 😉

[@shomusbiologyofficial]

You're welcome. Glad you liked it

[@sitthuson]

Practice pedigree #2 and #3, I see it as being "Autosomal R" & "X-linked recessive"...
The rules about skipping generation and male to female ratio don't entirely eliminate x-linked. those rules are not always reliable.
Care to explain?

[@cluelesshitchhiker1572]

Ig the #2 is X-Linked Recessive

[@gajappriyavenkatachalam3197]

Thank you very much sir, the way you teach the concepts is amazing

[@ayishathulbareerasp4967]

Sir i have a question: what is the purpose behind checking whether an autosome linked disorder is dominant or recessive using pedigree analysis?Is the treatment of autosome linked dominant disorder and autosome linked recessive disorder different?

[@varunazoologylecturer6387]

its make me to teach others very easily.thank u sir.

[@user-ep6ir5rf5j]

Neet wale like button😂

[@sherylmateva8777]

😂😂😂

[@SandeepKumar-nc9bm]

sir plz see again to question no 3 .It can also be x_linked recessive.

[@ramymelhem]

in the last example, could u not also say that it could also be due to an autosomal recessive condition? i mapped it out and it seems to work.

[@Kaandhal-or3gu]

It can never be recessive cuz its seen in all generations

[@SB-wy2wx]

The autosomal recessive pedigree's third generation: "sweet home Alabama"

[@jaanvi6083]

😂 u both go to evry video and say the same🙄😵🧐

[@chelseaj5455]

lol I just noticed that

[@nandhiniv2218]

@@jaanvi6083 yah 😂😂

[@jaanvi6083]

@@nandhiniv2218 i literally find this wtevr video i see yaar😩😴😒

[@azeemsiddiqui3853]

lmao besttttt

[@almirapebryana2876]

thankyou so much. i have exam tommorow, after watch this video i understand this pedigree methods

[@shomusbiologyofficial]

Glad it helped. Please share and subscribe

[@varunazoologylecturer6387]

sir thank u very much for giving important message.

[@mayukhroy5393]

-This video was very very helpful , Sir.

[@rasmiranjanbehera4118]

So simple concept...tysm sir 🙏🙏🙏🙏🙏

[@majidabdullah6598]

Sir with fue respect I want to know if the third problem solved is really autosomal recessive... Since in second generation the each of parents are coming from another family by considering that we can say that it's an x linked recessive trait. Correct me if I'm wrong.
Thank you

[@KJKP]

Problem #4 can be autosomal dominant. I think Shomu’s “golden rules” might be more like strong suggestions with frequent exceptions.

[@backstreetfan2887]

I agree

[@ImALLENITE]

Yes the 1st option is the correct BCOZ we have to take the left side also in our analysis 👍

[@sehunnight4198]

i spent a day a understanding my professors lecture about pedigree bcoz its included in my exam and i cant really understand it. and i watched your tutorial for the last minute, saw your vid and glad that u explain it well. now i can answer my exam later confidently. thank u so much. keep up the good work sir and keep safe. more power 💪🙌

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@shailendersingh3293]

Yaa it's an nice outlook we can lay emphasis on x linked dominant if we see in the chart the ratio of transfer of disease from moter to son is more than father to daughter so it can be a x linked dominant

[@dkbhasinhealthcare]

It very important topic study with logic clearly explained . Great sir, please explain Disease HAE ( heardetry Angioedema )

[@YouTubesucksman]

Atlast got an explanation in English

[@nnyadav5595]

hey in this video there is five female are affected,and only four males are affected.how can this problem is autosomal? there is no 50-50 chance of both male and female being affected

[@shreeshdas4507]

Thank you for uploading this video is very helpful

[@sthelilesihle5102]

Sir, when looking at individual 7&8, could we say it's autosomal dominant because the trait didn't skip the generation?

[@Yournightmare_435]

This is so helpful. Can’t thank you enough ❤

[@shomusbiologyofficial]

You're welcome

[@moniko7503]

Thank you! This helped so much!

[@07soumimondal91]

Guitar

[@sophiagarcia9018]

@@07soumimondal91 please what does that mean LMAO

[@lukelingo9181]

i have a question for the fourth pedigree in the second generation dosen't the daugther also get affected even tho the father isn't dosen't that mean the daugther is affected from the mother but isn't that like impossible if it's meant to be x linnked

[@chetnamittal7126]

o have a confusion that how can a trait be autosomal if more no of female are suffering from a disease

[@themadladprince430]

15:05, I don't understand why it would be a form of dominance. If both the parents were reccessive, then by crossing rr x rr, all the progeny are affected. Can someone please explain to me why it is a form of dominance?

[@skeletortheskeleton1357]

DUDE. IM CLOSE TO MIDTERMS AND THIS IS A LIFE SAVER. YOU ARE SO SMART. I LOVE YOU, THANK YOU!!!!!!!!!! KEEP IT UP!

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@lewisbeard8105]

Number 2 looks more like a case of Autosomal Dominant with reduced penetrance?

[@Anne0718]

great VIDEO. Thank u too much

[@PrernaSharma-fb6pl]

Thank you so much! Ur videos are the best!

[@AnuragSjngh]

Thanks for this video it's is very good

[@sindhujavb8551]

Thank you Sir, for providing such a clear explanation.

[@shomusbiologyofficial]

You're welcome

[@shikhadwivedidwivedi9869]

Please sir clear a doubt in A-R if assume three offspring then is it possible one offspring disease affected and other two not

[@ANGELAAR]

Beautiful presentation ..concepts very concise❤

[@shomusbiologyofficial]

You're welcome

[@Aesthetic_fact69]

Thank you so much sir 😊...... You explained it very well... But I didn't understand last two pedigree charts
According to me i think 2nd last is X-linked ressesive
And the last one

[@amairaniramirez8855]

Live saver! Thank you!

[@shomusbiologyofficial]

You're welcome

[@user-ll6td7nl3f]

i love you. you saved my midterm exam :)

[@shomusbiologyofficial]

Thank you

[@mr.abundant6449]

Thank you shomu bhai....

[@snigdhaaachi6066]

Thank you! Helped a lot.

[@shomusbiologyofficial]

You're welcome

[@esnh6372]

Amazing video, thank you so much!!!!!!!!!

[@shomusbiologyofficial]

You're welcome

[@vaishnavijadhav101]

thank you for such a nice explanation

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@nouraalmousa4958]

Salam , how are you ? ….. may I ask you please the Fragile X syndrome fall under which Inheritance PatternX-linked Recessive or Dominant (or both)?

[@zainabqureshi9178]

Walekumsalam

[@12hmbkjayant72]

TOTAL BANGER EXPLANATION

[@shomusbiologyofficial]

Thank you

[@nicoleviloria5184]

This is the first time I get it!!

[@chepkorirvicky7558]

You the best, I had to subscribe❤

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@pholososhamukuni9971]

THANK YOU SO MUCH...REVISING AND GOING WELL❤

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@joseluisboffillborroto5407]

Podría usted hacer la traducción de ese análisis del pedigree en idioma español?

[@bhatyasin2244]

Problem No. 3 follows x linked recessive inheritance...I have checked genotypically...
Please remove the confusion

[@hridaybaruah]

I THINK THE PEDIGREE AT 14:22 CAN ALSO BE EXPLAINED BY X-LINKED RECESSIVE DISEASE. WORKING OUT THE GENOTYPES MAKES IT LOOK LIKE A COMPLETELY PLAUSIBLE ANSWER. PLEASE DO CONSIDER IT ONCE AND I MAY BE WRONG BUT COULD YOU PLEASE EXPLAIN, ITS REALLY CONFUSING ME

[@daxaprajapati6581]

Thank u so much

[@indhuunni5181]

Is congenital defness of 2 son from normal parents a AR inheritance

[@zooharafique1826]

ThankYou! For this helping video ❤i didn't understand ever about these conditions of pedigree, but i must say after i saw this i can easily solve my all questions related to these four traits... 🌸🌸✨✨✨

[@gamingid648]

Very helpful keep going on bro❤️🙏❤️

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@moelol7113]

Hello from 2021, 18:04 sir this pedigree can work as sex-linked recessive

[@Astralarius_Zenith]

Thank you for this video! When we talked about this in class I was confused. Now I am having more clarity to the topic thanks to your video.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@rosaundra_eugenia]

In pedigree example 2 there are 5 females affected and 4 males affected, or am I wrong? Secondly, In pedigree number 3, couldn’t it be distinguished as autosomal recessive because 2 unaffected parents have an unaffected child on the left side and also because 2 parents have all affected children on the right side? Why is the right part where 2 affected parents have all affected parents identified as autosomal dominant?

[@avneetkamboj6219]

Very helpful video for understanding pedigrees

[@shomusbiologyofficial]

You're welcome

[@tinkeshpatidar3881]

Sir last wale quastion me outsider ko Carrer assume karna pad raha h......jo galat h....
Outsider ko humesha healdy male he manna padaga.....
So x link ressesive padigree hogi last wale quastion me

[@asuramunikavishadesilva371]

thank you so much sir!❤

[@shomusbiologyofficial]

Most welcome!

[@sathyavathimurugesan7099]

Sir but in 3rd example the mother were affected father was not then how in 2 nd generation she will be a carrier

[@poojagaddam3646]

Sir what is meant by Raw and forked pedigree . please give me rply

[@mahaavtarbabajineebkarolibaba]

exellent explaination... wow amazing

[@shomusbiologyofficial]

Thank you

[@shubhamsinghbartwal2028]

In pedigree 3 in case of affected father do not pass traits to their son. But sons can be affected by affected female..
But affected sons can come from affected mother, and affected female can come from affected father...
Why not x linked recessive or dominant...

[@mersijaalic3045]

You have explained it well, but i think that you should have written genotypes for each person. In that way we could see if we did the excercises well (3. and.4. exp). :)

[@manojmanly1057]

Nice explanation

[@aboutstudies123]

Explanation is good Sir. Thank you.
A small query Sir, "Among 1,5 and 7 Criss-Cross inheritance is observed. At 4 and 9 also depicting criss-cross inheritance. Why can't it be X-linked Sir?
Please clarify

[@aboutstudies123]

Regarding case 3

[@emmanuelchipeta1622]

It really has helped 💓 thank you

[@shomusbiologyofficial]

You're welcome

[@theamariecabaccan]

THANK YOU SM AAA

[@shomusbiologyofficial]

You're welcome

[@shafiahmadtalukder3543]

no 3 is confusing sir,please recheck this

[@FlatDrifting265]

this was taught better than my teacher. thank you.

[@shomusbiologyofficial]

You're welcome

[@sangyunlee9243]

Can problem 3 be xlinked recessive? because Gen 2-4 female is a career XA Xa.

[@shkaif2531]

In last question disease is transferred from mother to daughter so how it be a X linked disease

[@sohailshaikh6735]

Thank You Sir

[@shomusbiologyofficial]

You're welcome

[@theorange8755]

Wonderful thank you

[@shomusbiologyofficial]

You're welcome

[@user-ow9oz4pp4i]

Your voice is soo sweet pleasant to hear bro🤘❤️

[@shomusbiologyofficial]

Thank you

[@sahildhull2662]

thankyou very very very much...... sved my genetics exam.......

[@shomusbiologyofficial]

+Sahil Dhull thank you

[@rscreativevideo5417]

Shomu sir today I have answered all question except one from pedigree .It is all because of you.U r really god of biology.No words to say about u.soulful thanks from tamilnadu

[@taqwaejaz980]

Thanku Sooo much sir

[@shomusbiologyofficial]

You're welcome

[@IM-bc3tm]

Vary helpful thank you(:

[@shomusbiologyofficial]

You're welcome

[@philippeter198]

very helpful

[@pratibhasaggi6012]

Best video 👍

[@shomusbiologyofficial]

Thank you

[@abhishekpatel7335]

thanks.

[@anilkumarsharmazoology8333]

Thank you so much

[@shomusbiologyofficial]

You're welcome

[@asfa9039]

6:47 Are the lines written in the chart always validate???

[@ontheway9311]

THANK YOU SIR

[@shomusbiologyofficial]

You're welcome

[@badtameezdil3119]

Helpful

[@jishavinukumar1412]

Thank you sir for taking the class in English

[@shomusbiologyofficial]

You're welcome

[@allrounderteck5011]

Thank u brother

[@shomusbiologyofficial]

You're welcome

[@zosexo9190]

thank you

[@shomusbiologyofficial]

You're welcome

[@muktapal6240]

Thank u sir

[@shomusbiologyofficial]

You're welcome

[@gautomibasumatary5478]

Thank you sir.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@katsanlavers]

Вау, это очень круто! Спасибо

[@sahilrampal5723]

Very helpful

[@shomusbiologyofficial]

Thank you

[@arfinali495]

Thanks

[@shomusbiologyofficial]

You're welcome

[@joemariecastillo504]

really helpful my guy

[@shomusbiologyofficial]

Thank you