Driving from Tampa to Tallahassee, Florida

Head west on I-275 S
Distance: 2.8 miles
Use the right 2 lanes to take exit 39 to merge onto FL-60 W/State Rd 60 W toward Clearwater/Tampa Airport
Distance: 1.7 miles
Continue onto FL-589 N (Toll road)
Distance: 67.1 miles
Turn left onto FL-44 W
Distance: 5.7 miles
Turn right onto N Suncoast Blvd/NW US-19/NE US Hwy 19
Continue to follow NW US-19/NE US Hwy 19
Pass by McDonald's (on the right in 47.5 miles)
Distance: 143 miles
Turn right onto U.S. Hwy 19 N
Distance: 4.8 miles
Turn left to merge onto I-10 W toward Tallahassee
Distance: 16.5 miles
Take exit 209A to merge onto US-90 W/Mahan Dr toward Tallahassee
Pass by Burger King (on the left in 4.7 miles)
Distance: 7.0 miles
Use the left 2 lanes to turn left onto Magnolia Dr
Pass by Buffalo Wild Wings (on the right in 0.6 miles)
Distance: 0.7 miles
Turn right onto Apalachee Pkwy
Counties and Major Communities Passed Through:
Hillsborough County, FL
Tampa
Significant urban area with attractions such as the Tampa Riverwalk and Ybor City.
Home to Tampa International Airport (TIA).
Pinellas County, FL
Clearwater
Known for its beautiful beaches and the Clearwater Marine Aquarium.
Pasco County, FL
New Port Richey
Offers a charming downtown area and the Sims Park.
Hernando County, FL
Brooksville
Notable for its historic architecture and the Withlacoochee State Forest.
Citrus County, FL
Homosassa Springs
Famous for the Homosassa Springs Wildlife State Park.
Levy County, FL
Chiefland
Home to the Manatee Springs State Park.
Dixie County, FL
Cross City
Known for its small-town charm and proximity to the Gulf Coast.
Taylor County, FL
Perry
Offers a glimpse into the rural life of North Florida.
Jefferson County, FL
Monticello
Features historic sites such as the Monticello Opera House.
Leon County, FL
Tallahassee
The state capital, featuring Florida State University and the historic Capitol Building.
Notable Businesses and Landmarks Along the Route:
McDonald's: A familiar stop for fast food on US-19, located approximately 47.5 miles into the journey.
Burger King: Another fast food option, found on US-90 W/Mahan Dr in Tallahassee.
Buffalo Wild Wings: Located on Magnolia Dr in Tallahassee, known for its wide variety of wings and sports viewing.
Tampa International Airport (TIA): A major transportation hub near the starting point.
Clearwater Marine Aquarium: Known for its work with marine life rescue and rehabilitation.
Withlacoochee State Forest: A large forest area offering outdoor activities such as hiking, biking, and camping.
Homosassa Springs Wildlife State Park: Known for its underwater observatory and manatee viewing.
Manatee Springs State Park: Features crystal-clear springs and opportunities for diving and snorkeling.
Scenic and Historical Landmarks:
Tampa Riverwalk: A scenic walking path along the Hillsborough River in downtown Tampa.
Ybor City: A historic district in Tampa known for its Cuban influences and vibrant nightlife.
Monticello Opera House: A historic theater in Monticello, offering performances and events.
Florida State Capitol: Located in Tallahassee, an iconic building with a rich history.
This route takes you through a diverse array of Florida's counties, showcasing urban, suburban, and rural landscapes, and offers a mix of natural beauty, historic sites, and convenient amenities along the way.