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Stereochemistry: Meso Compounds, Diastereomers

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  • Опубликовано: 3 янв 2015
  • Meso soup! Here we will see how compounds with multiple stereocenters may be achiral overall, if they have an internal plane of symmetry (meso compounds) or an inversion center. In addition, we will define and discuss diastereomers. Now where's that soup...
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Комментарии • 236

  • @juliemolina9702
    @juliemolina9702 2 года назад +58

    Dave you beautiful wealth of knowledge. All of my tuition should go to you, you're better than my professor hands down.

  • @onslaabidi5254
    @onslaabidi5254 7 лет назад +49

    i just wanna tell you u saved my life ..Thank u so much ..i had stereochemistry exam today and thanks to ur explanation i succeeded it

  • @elizabethknoll5307
    @elizabethknoll5307 5 лет назад +41

    Wow, it took me a week to try to understand what a diastereomer was based on lecture notes, libretexts, etc but you explained it in 15 seconds with a definition that made SO much more sense. Thank you!

    • @knownstranger2570
      @knownstranger2570 Год назад +1

      Are u in school or are you preparing for some exam?

    • @thelizrd_
      @thelizrd_ Год назад +1

      @@knownstranger2570 yes lol I was. 4 years ago lmao

  • @patriotguy12
    @patriotguy12 8 лет назад +112

    Thanks Dave, I'm studying for the mcat and these explanations you have are great and click so well when I'm reading the prep books.

    • @KoToKo90cHaN
      @KoToKo90cHaN 6 лет назад +4

      so did u pass

    • @alegim98
      @alegim98 5 лет назад +2

      How was your mcat

    • @gtarules1
      @gtarules1 4 года назад +5

      @@KoToKo90cHaN lol no reply 3 years from his comment.

    • @lemickey4204
      @lemickey4204 2 года назад +1

      Update? Dr yet?

    • @patriotguy12
      @patriotguy12 2 года назад +27

      @@lemickey4204 currently in residency : )

  • @TheToxicMegacolon
    @TheToxicMegacolon 5 лет назад +11

    I've been having a tough time understanding this off the bat and this video has cleared a lot of things up, thank you Professor Dave!

  • @sana.xxyyyy
    @sana.xxyyyy 5 лет назад +5

    This is the best explanation of optical isomers I have seen so far :-)
    You are the voice of the ORACLE of organic chemistry

  • @Gangsta0wns456
    @Gangsta0wns456 5 лет назад +12

    You make o-chem concepts very digestible! Great stuff professor dave!

  • @eduardoparedes8200
    @eduardoparedes8200 8 лет назад +8

    That was amazing, thank you so much! My orgo book never even mentioned the concept of an inversion center...

  • @jhazellednaco1569
    @jhazellednaco1569 6 лет назад +5

    I'm studying for my chemical engineering board examination and your videos really helps me to review the chemistry concepts. :) Good job sir!

  • @muditsharma4288
    @muditsharma4288 6 лет назад +5

    You’re so good man. I wish the world had more teachers like you.

    • @hank561
      @hank561 2 года назад

      Where are you now???

  • @ShubhamSingh-fp4wf
    @ShubhamSingh-fp4wf 8 лет назад +28

    your are the best professor

  • @mubmub1358
    @mubmub1358 6 лет назад +86

    You are the Jesus of Ochem. Thank you so much!

    • @user-nv1pu3qg1v
      @user-nv1pu3qg1v 3 месяца назад

      No one compares to Jesus in anything

  • @jumeepark3302
    @jumeepark3302 8 лет назад +4

    Thank you for the best miso soup!!! Its the best miso I had. I wish you could able to offer private tutoring! Your videos are helping me so much!!! Thank you so much!

  • @randaltaco3280
    @randaltaco3280 8 лет назад +12

    Studying for Mcat, thanks for clarification of diastereomers.

  • @shenaliranasinghe8764
    @shenaliranasinghe8764 4 года назад +5

    That was so good, You are a life savior!!! Thank you Dave!!!!

  • @bushidosurvives5779
    @bushidosurvives5779 8 лет назад

    fantastic explanation. i was sitting here spinning my wheels when it came to meso compounds and inversion points. your method of reflecting the molecule across a mirror and then rotating it 180 degrees prior to comparing it with its parent really clicked and has made this material painless. your visual explanation of inversion points was spot on as well. thanks.

  • @shreyasrk7542
    @shreyasrk7542 6 лет назад +1

    You are no doubt the best professor that exists.... According to me at least.......a big salute to you.

  • @chaitanyashahare2734
    @chaitanyashahare2734 2 года назад +1

    i wish i had discovered your channel a couple years ago that would have been such a help. some of the things I never understood then I'm getting them now because of these videos thank you so much for your effort and your teaching is flawless!!!

  • @Kai1995__
    @Kai1995__ 7 лет назад +3

    i never knew that breakbot is also good at organic chem. anyway you da real mvp, greetings from Indonesia

  • @TheTurtlelover4
    @TheTurtlelover4 3 года назад +3

    not me watching these videos right before the exam

  • @randiniranasinghe6634
    @randiniranasinghe6634 Год назад

    I don't have enough words to say how thankful I am to you professor Dave. Thank you very much ✨

  • @CookiesOnFridays
    @CookiesOnFridays 6 лет назад +1

    Thank you so much for explaining this to me. Was confused, but now it's made clear. You sir, have saved me a lot of time and stress. THANK YOU!

  • @vaedkamat484
    @vaedkamat484 Год назад

    every day when I come home from school I watch one of these videos and I am always curious to what's new on the board at the beginning of hte video.

  • @elletronmatic
    @elletronmatic 7 лет назад +2

    Thank you so much. You truly are a fantastic teacher, keep doing what you do!!

  • @davidwells9709
    @davidwells9709 5 месяцев назад +1

    This video is solid gold

  • @jonathanlai6100
    @jonathanlai6100 2 года назад

    SO CLEAR. you have the incredible gift of teaching and explaining

  • @mariaavedissian4853
    @mariaavedissian4853 8 лет назад +5

    Professor Dave, You are the best!

  • @wesonga7614
    @wesonga7614 7 лет назад +6

    you make organic chemistry look so easy...thanks
    where can i get more biomedical tutorials

  • @mariafernandadelarosasante4463
    @mariafernandadelarosasante4463 3 года назад

    This is the video I was looking for, you save my life and probably my next organic chem exam :)

  • @asiaeamdani2054
    @asiaeamdani2054 2 года назад

    can i hug , u saved the ploblem in my head that my teacher coundnt solve, MUCHAS GRACIAS

  • @rithe07
    @rithe07 7 лет назад +4

    Thank you for this, and thanks for captioning

  • @cinthiayanethcastilloloera3276
    @cinthiayanethcastilloloera3276 4 года назад

    Thank you so much, you're one of the best channels of chemistry I know. Thank you so much again.

  • @salomezhozhadze9071
    @salomezhozhadze9071 10 месяцев назад

    ive been trying to get that since my first year of medschool. thank you

  • @simmiahuja8324
    @simmiahuja8324 5 лет назад +2

    You are great at organic Dave sir

  • @divakarhariharan5541
    @divakarhariharan5541 3 года назад

    I Am watching ur vedios from India, Ur explanation about this topic is be easy to understand thank you so much sir

  • @sriarvind7312
    @sriarvind7312 Год назад

    It seems so easy when u explain, while I was stressing so hard at school, tsym!
    but could u keep the camera fixed, the movement is distracting
    Edit: just realized this was 8yrs ago

  • @shatakshisharma5594
    @shatakshisharma5594 6 лет назад +2

    U r my lifesaver... Thank u sir.. 🙏🙏🙏 i was going mad due to confusions in this topic... 😂😂

  • @silviare73
    @silviare73 6 лет назад +1

    Thank you Dave! I'm an Italian chemistry teacher and I love your videos... I'm trying to make my pupils to learn stereochemistry in English 🙈😊

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  6 лет назад +2

      very cool! i would suggest my new italian tutorials as well but they are probably the last ones who need that :)

  • @KittyLickPart2
    @KittyLickPart2 2 года назад

    I feel like if you were my private tutor I could drop out of college because I wouldn't need it. Thank you so much for the awesome content!

  • @lev4654
    @lev4654 7 лет назад +4

    Thank you so much!
    It's really helpful
    and of course I subscribed your channel.^^

  • @nathaliaferraz9982
    @nathaliaferraz9982 8 лет назад +5

    I'm in love

  • @montsekaye8808
    @montsekaye8808 3 года назад

    I'm back again from grade 11 to grade 12👀
    Thanks dude your explanations are always the best

  • @jamesgarraway5949
    @jamesgarraway5949 5 лет назад

    Don't think you could've been any clearer, thank you!

  • @BarbieLovethDominic
    @BarbieLovethDominic 3 месяца назад +1

    Thank you 😊

  • @heiitsme182
    @heiitsme182 3 года назад +1

    Thumbs up to Professor Dave👍, thank you

  • @likabakhturidze8191
    @likabakhturidze8191 4 года назад

    i love your lessons! thank you for helping me pass my exams

  • @ae5704
    @ae5704 3 года назад

    Totally came in clutch for an Oxford interview!

  • @hannahmushtaq6362
    @hannahmushtaq6362 3 года назад

    i love you i cant thank you enough after 2 years i get this!!

  • @mslovelee86
    @mslovelee86 8 лет назад +2

    Subscribed, thank you so much it helped me a lot.

  • @13Drumsticks
    @13Drumsticks 8 месяцев назад

    Beautifully explained, thank you!

  • @user-lt2lm8ei3i
    @user-lt2lm8ei3i 10 месяцев назад

    you explained this so well. thank you so much

  • @lakers4shoPSD
    @lakers4shoPSD 7 лет назад

    For the example compound at 03:21, I think if you rotate along the C-C single bond, you'll find a conformation that gives you the desired plane of symmetry, hence achiral.

    • @lakers4shoPSD
      @lakers4shoPSD 7 лет назад

      by C-C I mean carbon-carbon

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 лет назад +1

      that's right, an inversion center is just another way of identifying it, but either way it's achiral!

  • @shaoanchen2871
    @shaoanchen2871 6 лет назад

    Great for students like me who don't bother going their lectures. precise and comprehensive

  • @SuzannesTutoring
    @SuzannesTutoring 6 месяцев назад

    Thank you! Question: when given only the Chemical's name, for example "phenylalanine", and asked to draw it 3D, how do you know which substiuent group lies in the same plane, which goes in front, and which goes in back?

  • @sirrchris249
    @sirrchris249 Год назад

    Great prep for DAT

  • @sujeetverma4259
    @sujeetverma4259 7 лет назад +3

    thanks man
    this helps a lot

  • @rimjhimshukla4066
    @rimjhimshukla4066 6 лет назад

    Great lectures..never knew stereochemistry could get this easy
    Kudos!

  • @sohamkumar9518
    @sohamkumar9518 10 месяцев назад

    every time I had a nickel when I was confused by my professors and had to revisit this playlist I would quit college and comfortably live the rest of my life

  • @randominternetprofile8270
    @randominternetprofile8270 7 лет назад +1

    Thanks Professor Dave

  • @oliviaraypole8745
    @oliviaraypole8745 4 года назад

    You taught me all of my ochem knowledge.. THANK YOU

  • @Paraselene_Tao
    @Paraselene_Tao 2 года назад

    Perfect explanation again.

  • @ushaaaaa
    @ushaaaaa Год назад

    Pls do video on optical activity

  • @tutor001
    @tutor001 2 года назад

    very helpful!! and quite easy to understand

  • @JesusChristTheOnlyTruth
    @JesusChristTheOnlyTruth Год назад

    Hi Dave! I have a question regarding the diastereomer part. My first question is - Why didn't you write -Br on the left side and -OH on the right in the mirror image of the molecule? And my second question is - Do the wedge bonds become dash bonds and vice versa in their respective mirror images? If yes, then, why?
    Thank you so much for the video! May God bless you!

  • @catherinechoi97
    @catherinechoi97 6 лет назад +1

    wow you are amazing at explaining thank you so much!!

  • @vinowithvoices
    @vinowithvoices 7 лет назад +1

    hello sir,why should we rotate the compound 180 degrees and then placed it on the original compound?
    as i know we have to place the mirror image on the original compound.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 лет назад

      we just have to rotate it or flip it in some way so as to try to align all the atoms in the two molecules, whatever method you use is fine.

  • @shoroqhuseen1838
    @shoroqhuseen1838 3 года назад

    Wow amazing lesson 👍 now I anderstand the topic but please can you put some few questions in the end of the lesson for us !?! 🙏

  • @jasminedragon9
    @jasminedragon9 5 лет назад

    Fantastic explanation!

  • @BoshraAsadi-jx2gc
    @BoshraAsadi-jx2gc 4 месяца назад +1

    Wow perfect ❤

  • @imanetc
    @imanetc 7 лет назад +1

    This helped a lot thank you!!!

  • @khalifabio
    @khalifabio 9 месяцев назад

    in monosacchaids, can two diastereoisomers be of different series (one ose belonging to the D series and the other to the L series, e.g. L-glucose and D- tallose, which differ in the position of the OH on carbons 3 and 5)?

  • @rassimsimou1594
    @rassimsimou1594 Год назад +1

    Good

  • @DOCB-op1qc
    @DOCB-op1qc Год назад

    still dont understand. how is the top left is even counted. if its based on AMU Br is 1, CH3 #2 then the hydrocarbon bridge CH2.

  • @Prakash-fh7ic
    @Prakash-fh7ic 5 лет назад

    thanks a lot sir
    Many concepts are clearing

  • @anushaashna4383
    @anushaashna4383 6 месяцев назад

    Thank You!

  • @rima952
    @rima952 3 года назад

    Thank you professor dave .I want to know how to know How many stereoisomer present of a compound 🙏🏻

  • @georgesmaroun1406
    @georgesmaroun1406 8 лет назад +1

    Great video!

  • @manasmhatre8200
    @manasmhatre8200 6 лет назад

    Please explain in presentation method which we will understand more easily and take more and more examples .

  • @sciencenerd7639
    @sciencenerd7639 2 года назад

    wow! very nice explanation.

  • @anikatabassum4462
    @anikatabassum4462 9 лет назад +1

    very helpful! thanks!

  • @sandyoliva7179
    @sandyoliva7179 9 лет назад +3

    thank you for this video!! but I have a question what is the difference between an epimer and an enantiomer ?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  9 лет назад +10

      +Sandy Oliva an enantiomer is the precise mirror image of a molecule, so all the stereocenters are inverted. epimers are diastereomers with more than one chiral center, but differ in only one of those chiral centers. so if a molecule is RRRR, its enantiomer is SSSS, but an epimer of RRRR can have only one S, the rest must remain R.

    • @sandyoliva7179
      @sandyoliva7179 9 лет назад +1

      +Professor Dave Explains thanks a lot!!!!!!! :D

  • @abdelrahmanmetwally581
    @abdelrahmanmetwally581 4 года назад

    You are awesome 🦸‍♂️ my hero who saved me

  • @dilettanter
    @dilettanter 4 года назад

    I like this - it’s all very clear.... except for what did you mean by rotate 180 degrees at the beginning when discussing trans 1,2-dicholorocyclohexane? I can’t seem to see it (although I can see there is no plane of symmetry within the compound, making it not identical to its mirror image ). Did you mean flip it over ? rotate?

  • @its_robbietime1333
    @its_robbietime1333 5 лет назад

    okay geat video but whats more potentially interesting is how does this affect the way some medications interact with your brain

  • @sinaabedini7487
    @sinaabedini7487 4 года назад

    You are a true master

  • @kuusshhh
    @kuusshhh 2 года назад

    i have a question tho..at around 5:15 you say that if we flip the mirror image ..so on flipping the mirror image,wouldnt the stereocentres also change like..
    the comp had the centres in the orders R-S
    its mirror image would be S-R
    and on flipping in again , wouldnt it become R-S again..[otherwise the oh and br also wouldnt go into the plane so??]i dont get it
    nvm i was unaware of what the r and s actually meant and now its perfectly clear to me

  • @xpandax5542
    @xpandax5542 7 лет назад +1

    Amazing vid!

  • @sayyedizazyousafzai8112
    @sayyedizazyousafzai8112 3 года назад

    great sir

  • @user-ug3bg7ey2s
    @user-ug3bg7ey2s 10 месяцев назад

    we love u professor dave

  • @demYcheezu
    @demYcheezu Месяц назад

    thank you!!!!

  • @tomcruise9317
    @tomcruise9317 2 года назад

    Cant understand 😪 give eg with glucose sir

  • @ruthmrks
    @ruthmrks 8 лет назад

    you explained it perfectly! Thank you!!!!! :)

  • @kirmizikitap8834
    @kirmizikitap8834 7 лет назад +1

    Really thank youu

  • @ewwxaca
    @ewwxaca 5 лет назад

    Thank you.

  • @ibdaakojan9401
    @ibdaakojan9401 3 года назад

    you made my life easier

  • @Obsa_abdisa
    @Obsa_abdisa 6 месяцев назад

    Tnks

  • @najwafarhanabintiyahya2783
    @najwafarhanabintiyahya2783 3 года назад

    Thank you so so much!!

  • @nadaal-saadi3984
    @nadaal-saadi3984 4 года назад

    Thank you so much 🙂

  • @walelighkabede1385
    @walelighkabede1385 3 года назад

    Why don't our teachers explain like this? Thanks bro

  • @akithjayalath8686
    @akithjayalath8686 3 года назад

    Dude thanks, just thanks🙏