Is THIS the NEXT BIG THING in Skincare?

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  • Опубликовано: 5 фев 2025
  • Looking at the science behind EGF to see if it's worth our money!
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Комментарии • 977

  • @mrmvianna
    @mrmvianna 2 месяца назад +128

    Congratulations! I am a 48-year-old perimenopausal woman, a scientist, and a cell biology professor.
    You did an amazing job analyzing data, scientific bias, and commenting on important and limiting aspects of topic treatments (passing through the skin layers and basal membrane and stability)!
    I subscribe to your channel and have not seen your videos for a while, but today this one showed up (after I watched the one about retirement). Please keep doing this! This was truly great and I am sure it took a lot of time and dedication, so thank you!

    • @tracymiddleton8580
      @tracymiddleton8580 2 месяца назад +6

      This video also showed up on my feed after I watched the retirement video.

    • @pola.3068
      @pola.3068 2 месяца назад +1

      Same for me!

    • @rosiebenitez-groh7700
      @rosiebenitez-groh7700 2 месяца назад +1

      Me too! Hmmmm sounds like there was some sort of Shenanigans you called out.

    • @MonumentGigi
      @MonumentGigi 2 месяца назад

      Me too!!

    • @MsTinymark
      @MsTinymark 2 месяца назад +1

      Thank you, Angie, I've used them for 6 months and not re-ordering. They don't work! I used TNS advance xo

  • @glucksmosaik2342
    @glucksmosaik2342 Месяц назад +6

    Dear Angie, thank you so much for your work. I ´m a dentist from Germany and a skin care nerd. I really appreciate your passion and your work. I’ve learned so much from you! THANK YOU! Don’t retire please. You’re so outstanding and special. You put so much passion and time in research and your reviews are honest and authentic.

    • @Silvie.1
      @Silvie.1 6 дней назад

      A fellow German and skin care nerd❤

  • @Lil-Be
    @Lil-Be 4 месяца назад +69

    I am an esthetician and I wish we had teachers like you at school. They knew nothing compared to you. Great video Angie! 💕

  • @paulachristie7807
    @paulachristie7807 4 месяца назад +660

    I am sticking with Tretinoin, an antioxidant serum, and a moisturizer with peptides. At 73 I’m going to embrace my wrinkles as proving I’ve had a life well lived.

    • @joycebenvenuti4782
      @joycebenvenuti4782 4 месяца назад +30

      Me too … just turned 70 ,I’m beyond fine lines and I’m happy with the Tretinoin and all my serums .

    • @beth8678
      @beth8678 4 месяца назад +21

      Me too at 63 😊

    • @elizabethmyers1328
      @elizabethmyers1328 4 месяца назад +29

      Same. 66 here. Loving my skin and happy with it. Retinol, antioxidant serum, peptide moisturizer, sunscreen. Weekly AHA peel. That's it.

    • @melissavidic2895
      @melissavidic2895 4 месяца назад

      @@joycebenvenuti4782 Same at 59 I’ll stick with my retinaldehyde, Peptide night cream and my serums.

    • @evabothwell454
      @evabothwell454 4 месяца назад +13

      ​@@elizabethmyers1328what antioxidant do you use? & moisturizer w/ peptides thank you 😊

  • @heidifisk2830
    @heidifisk2830 2 месяца назад +15

    Angie - this is the perfect example of the type of video I enjoy. I love it when you go full on nerd and give the absolute truth of skin care products. This is saving your viewers a lot of time and money. Well done. 👍

  • @jenniferglenn3167
    @jenniferglenn3167 2 месяца назад +6

    I’m 51 and have been watching your show for the last 7 years. If you still have it on you please keep going. I love your channel….its shown me that you don’t need to pay big bucks to change your skin and reverse damage and signs of again. Thank you so much for all your work!

  • @kam0406
    @kam0406 4 месяца назад +188

    I just went to a funeral for a friend who was only 52. She was a nurse practitioner, in the Air Force, a wonderful wife, mother , daughter, sister and friend to all. She leaves behind two beautiful boys who are college age. All I can think of right now is that aging is a blessing. Looking good is great, but what Heather would not have traded to still be here with her boys and husbands, family and friends!

    • @baharscorner8842
      @baharscorner8842 4 месяца назад +12

      May your friend rest in peace. I totally agree with you on what you say.

    • @Canuckbelgo
      @Canuckbelgo 4 месяца назад +2

      I'm very sorry for the loss of your friend. Ugh, 52. My younger sister is 53. May I ask what was the cause of her passing ?

    • @CarrieAnn72
      @CarrieAnn72 3 месяца назад +4

      I lost my best friend too she was just 50! So sorry for ur loss. When major things like that happen it puts things in a different perspective. ❤😢

    • @rd7726
      @rd7726 3 месяца назад +6

      Aging meaning getting older is a blessing but some of us don't enjoy the outer signs and wants to slow down the outer effects of aging.

    • @cmilk9082
      @cmilk9082 3 месяца назад +7

      So many younger and middle aged people dying since 2020. It makes you wonder if any widespread medical treatments/interventions since 2020 could be contributing to this…

  • @yinze0089
    @yinze0089 2 месяца назад +2

    You put so much time and energy into your videos. You are appreciated immensely!

  • @catharinecowan4514
    @catharinecowan4514 4 месяца назад +104

    Frantically waving nerd flag - excellent job!! You basically did a PhD thesis literature review in this video! Scientific research isn’t perfect but you consistently provide excellent summaries of ALL the data, good and bad, with enough nuance for folks to make their own choices. Nuance is sorely lacking in media these days, and I deeply appreciate your work and contribution. I’m sure these videos don’t perform as well as others, but please don’t stop making them!!!

    • @adria89
      @adria89 4 месяца назад +5

      These are my favorite type of video that Angie makes.

    • @KJB0001
      @KJB0001 4 месяца назад +1

      Yes!! Most of her OG videos were QUITE technical

  • @anniesadventures5133
    @anniesadventures5133 8 дней назад

    Wow, thank you for putting so much time into this. I've been considering this purchase for a while now, but this seals the deal. You’re incredibly informative and realistic. 💚✨

  • @lindagoldman2351
    @lindagoldman2351 4 месяца назад +12

    Angie, I have been watching you ever since you practiced your make up techniques on your then husband (funny video).
    Speaking as a person with a medical background, I am very impressed with the depth of your “deep dive” into this study. You are without a doubt, one of the most trusted and respected influencers on RUclips. Thank you for that.

  • @margarethayes4106
    @margarethayes4106 2 месяца назад +1

    Well done as always, Angie! With regard to other You Tube channels, you are in a league of your own!

  • @user-ij5ek4qw9i
    @user-ij5ek4qw9i 4 месяца назад +8

    Thanks Angie, we so needed that debunking, because at 78, it is tempting to try the next miracle cream. I have also been using Tretinoin for a few years with positive results, but I find my skin has gotten super dry no matter how emollient the creams are. I have chosen to reduce my use to no more than 3 times a week and it has really helped. My skin is looking a lot healthier and plumper. Thanks again

  • @darlenebartos3889
    @darlenebartos3889 Месяц назад +1

    I’m impressed w how well you articulate all these studies! You are very smart lady

  • @margieryne6220
    @margieryne6220 4 месяца назад +172

    Hi, Angie, you are starting to sound like a scientist, you really dug in deep! Thank you for all your hard work, I appreciate all you do for us! Have a great weekend!❤️

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад +32

      I didn't know if I'd find my way back from that rabbit hole!! lol 😆 It was fascinating!

    • @margieryne6220
      @margieryne6220 4 месяца назад +2

      @@AngieHotandFlashy 😂❤️

    • @guadelot
      @guadelot 4 месяца назад +8

      Her dad is a scientist ❤❤❤

    • @jann3443
      @jann3443 4 месяца назад +4

      Angie is her father's daughter for sure!! I love that.

    • @CherylBerryl
      @CherylBerryl 4 месяца назад +4

      Well, her Dad IS an actual Scientist, so, as they say, "little apples don't fall far from the trees!" Lol.

  • @lauriehalverson7755
    @lauriehalverson7755 2 месяца назад

    Thank you, Angie! My nerdy self watched till the end and loved it. 🥰
    Also, like other comments, I watched your ‘retire’ from YT video and you’re now showing up in my feed again!
    Please keep sharing because the variety of your videos, some requiring extensive research, is so helpful, needed and most importantly in my opinion….wanted by most peeps.
    Thanks again and keep shining your light, inside and out. 💛✨

  • @lorainemcgillivray77
    @lorainemcgillivray77 4 месяца назад +249

    Hi Angie I was a Registered Nurse for many years and won’t buy growth factors either. The possibility of proliferation of skin cancer cells in the human bioengineered stuff is a big no and plant based - well I am not a plant 😂.
    I have rosacea and eczema so my skin barrier is chronically impaired therefore I use a lot of caution when choosing skin care. My rosacea hates retinoids during true menopause (I could use them carefully prior to becoming fully menopausal), but I believe in their efficacy as a topical treatment. My active of choice is azelaic acid- it has made the biggest difference in how my skin looks. Obviously I use spf and as I live in the UK use ultrasun or Evy with their more longwear modern filters (ultrasun is available on prescription for skin cancer patients btw). Niacinamide is nice, my skin absolutely hates vitamin C and peptides are hydrating😂. There is no miracle cure for aging and I personally am happy to have lived long enough to even worry about it. I was involved in cancer nursing for many of the years spent in that profession and trust me not everyone lives long enough to worry about aging/wrinkling. I want calm, hydrated and moisturised skin but just embrace the signs of aging as a life lived. My smile lines are far more prominent than frown lines so it is a reflection of that life on my face.
    I am not however on camera on social media with all the pressure about how I look that entails, so no judgement etc. I do think procedures will have a far more obvious impact than anything topical, so for those buying 300$ serums saving that money towards a procedure may get you better results. Best wishes x

    • @Cinnamon349
      @Cinnamon349 4 месяца назад +3

      Have you tried over the counter butt paste for rosacea? Like desitine? Works!

    • @halfamo2422
      @halfamo2422 4 месяца назад +6

      Yes, here for the azelaic acid - makes huge difference to pigmentation (the only thing I really want to get rid of) - and niacinamide (my 66 y o skin was parched, nothing worked, until I discovered it, funnily enough in Cerave) Retinal works well, but so does a 1x week fruit enzyme peel. And why IS vitamin c so problematic - I sweat that was what wrecked my skin barrier and started off kp! Growth factors are such a half-understood science - def not going there.

    • @user-xc7iq4cm8t
      @user-xc7iq4cm8t 4 месяца назад +5

      @@halfamo2422- what tyoe of enzyme peel?

    • @reesesha2289
      @reesesha2289 4 месяца назад +11

      Agreed 100 %, past oncology nurse here too!

    • @paulgillespie8813
      @paulgillespie8813 4 месяца назад +2

      Totally agree about vit c! Rosacea is such a pain. I'll try the A acid you mention.

  • @trishpugelli5371
    @trishpugelli5371 Месяц назад +1

    I am sooooo glad you put out this video...I have been using growth factors both TNS and Neogenesis for years, and hate plunking out the enormous cash for it...after I am finished with the 2 I have, I will no longer be buying a growth factor... thank you thank you thank you and Merry Christmas xo

  • @MischiefManaged-c5k
    @MischiefManaged-c5k 4 месяца назад +6

    Not what I expected! I’m glad I watched to the end bc I almost skipped straight to the links you shared to buy something you were sharing in the description box 😱
    NO WAY will I be adding a pre-existing-skin-cancer-developer into my skincare routine 😳 (Maybe adjust the title to this one?) Love you AHF!! And thank you for your research! You’re my hero ❤

  • @suemahoney7330
    @suemahoney7330 4 месяца назад +2

    Such an amazing scientific deep dive. This is exactly why I take Angie's advice. If you listen to anyone else, (but why would you), it would be interesting to see what they say about these products. And how may they link for you to purchase. So many RUclipsrs are all about the hype so you purchase and they get the kickback. Everything that Angie recommends has helped me immensely! Thank you for all you do!

  • @lightseeker108
    @lightseeker108 4 месяца назад +5

    Thanks, Angie. This is a great example of why you have so many fans for your channel. You could just tell us buy this and get a little commission, but you’re basically giving us the information to determine which things are effective and which things are a waste of money and we appreciate you for that. I too come back to your basic recommendations of agency tretinoin, timeless vitamin C (Effective and affordable ), Omnilux red light skin mask, and your common sense when it comes to saving money on things like moisturizers if you’re getting your active ingredients elsewhere.

  • @aprilwichman98
    @aprilwichman98 4 месяца назад +151

    I tried both Skin Medica and Neocutis and they didn’t do a thing to improve my skin. Do not waste your hard earned money. I’m 58 and am constantly getting compliments. I use products from Neutrogena, Cosrx, the Ordinary, and Timeless. They do a better job to keep my skin balanced and healthy and they don’t break the bank!

    • @danielmusca9930
      @danielmusca9930 4 месяца назад +1

      What do you use from timeless. Wa Ted to try vitamin c

    • @helenorgarycrevonis2022
      @helenorgarycrevonis2022 4 месяца назад

      Thank you

    • @kam0406
      @kam0406 4 месяца назад +9

      CosRX is the real deal! Korean skin care and sunscreens have improved my sensitive skin. It’s too bad the useless FDA won’t approve the Korean filters here. I really think Korean sunscreens might put the American brands out of business.

    • @karenfarrell6158
      @karenfarrell6158 4 месяца назад

      Ingredients are too toxic

    • @phyllisaugustyn7963
      @phyllisaugustyn7963 3 месяца назад +2

      TNS essential serum and neo cutis eye serum worked miracles for my skin, be your own judge.

  • @deborahbinnie5652
    @deborahbinnie5652 4 месяца назад +78

    Thank you for the scientific deep dive. You really did your homework. I'll stick to retinol, sun screen and peptides.

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад +17

      Me too!

    • @amielynn2657
      @amielynn2657 4 месяца назад +2

      What is a good peptide?

    • @janekraft1359
      @janekraft1359 4 месяца назад +2

      I'm 71 an have used tretinoin since early 40s. I'm workout, take supplements
      I don't look 20, but I look good for my age. Stem cells creep me out. Used for growing other body parts.

  • @christig195
    @christig195 2 месяца назад +2

    Hi Angie! If you haven't already done a "deep dive" into Vaginal Estrogen Cream (Estradiol 0.01%), applied to the face for anti-aging, could you please address this very popular topic. I trust your research and reviews. I am a 73 year old esthetician. The cost factor is much less than some other more expensive products. I know that one brand of Estriol is manufactured by a company called Alloy. Estriol is supposed to be a slightly milder form of Estradiol and is said to have no systemic effect.

  • @LisaNix2
    @LisaNix2 4 месяца назад +9

    Thanks so much Angie! I asked for this video from you months ago, so I appreciate all your research to help me understand this. My dermatologist told me not to use Growth Factors because I’ve had melanoma skin cancer in the past. I think this is important for people to understand.

  • @tracymiddleton8580
    @tracymiddleton8580 2 месяца назад +2

    Growth Factors …..and Stem Cells are the rage now! Excellent relevant subject matter! (Appears to me RUclips wants to keep you active!). This is my second pop up of one of your videos today. I am so happy I saw this one!

  • @practicebalance
    @practicebalance 4 месяца назад +3

    I’ve done sunscreen, vitC and rx retinoid for 15+ years. I added Skinmedica TNS serum a few years ago, and I noticed a significant improvement in my skin’s texture. It’s so soft! So I’ve continued to use it.

  • @denisemishkel7473
    @denisemishkel7473 4 месяца назад +6

    You just saved me tons of money .. I had used the TNS as well and was always questioning the results . We appreciate you so much !!❤

  • @svetlanaanthony2675
    @svetlanaanthony2675 4 месяца назад +8

    Neither Skin Medica nor Neocutis, used for at least a year, did anything for my skin. I also tried it with microneedling. Not worth the money in my opinion. Tretinoin, occasional microneedling, and Omnilux mask worked and continue to work. People ask me what do I do to get a glass-like skin at 52. Don't need expensive skincare, need consistency and appropriate for the age ingredients. Great video, Angie!

  • @sherylbeamer7189
    @sherylbeamer7189 4 месяца назад +14

    ~THANK YOU ANGIE!~ I tried the TNS $280 gf serum a few years ago, took before and after pics and NOTHING! No improvement whatsoever, it was throwing hard earned money down the drain. I so appreciate your analysis of the statistics and data. It’s interesting how very small the study sample sizes are🤓🧐. As always excellent video!💕👏🏻🙏🏼🌷

  • @Fiesty-1
    @Fiesty-1 4 месяца назад +146

    Blue is your color! It softens your blonde and makes your eyes pop. You look beautiful.

    • @marilynshapiro516
      @marilynshapiro516 4 месяца назад +1

      So glad or did this video, I did try the skinmedica advanced my skin felt smooth but when it
      Ran out I used Kiel’s hyraulonic serum which also felt smooth for much less money, will not buy growth factor serums again. Thanks again for this video

    • @nancymccormick7567
      @nancymccormick7567 4 месяца назад +1

      Agree!! Angie looks especially beautiful today!

    • @mam564
      @mam564 4 месяца назад +2

      I'm guessing that Angie used blue or purple shampoo to soften her hair color. It really works!

    • @skyeblu1722
      @skyeblu1722 4 месяца назад +1

      She looks good in anything she wears!

  • @mermaid4122
    @mermaid4122 2 месяца назад

    Thank you for the scientific study. Angie, your brilliant and gorgeous! I have missed seeing your uploads for a long while. I just thought you went to another platform until your last upload. Thrilled your videos are in my feed again :)

  • @juliebacon3027
    @juliebacon3027 4 месяца назад +4

    Thank you for doing a deep dive on this subject. Very informative. As someone who has had melanoma twice, I will be steering clear of these products! ❤

  • @marxalenina
    @marxalenina 2 месяца назад +1

    You saved me a lot of money. Thanks Angie!!!

  • @renejohnson37
    @renejohnson37 4 месяца назад +16

    Thank you. I appreciate your critical eye when reviewing research.

  • @Yogawithyoda
    @Yogawithyoda 4 месяца назад

    Thank you for taking the time to look so thoroughly into these ingredients- this is why you are the queen of woman at midlife- you are detailed and thorough… I am grateful for your work Angie! You have an amazing ability to be tenacious and wise! Thank you for the details and it really sets you apart! ❤

  • @anniesimone
    @anniesimone 4 месяца назад +11

    I've been using "Bioeffect" Egf serum (a brand from Iceland, using a patented egf ingredient) for some years now during winter time. (live in Scandinavia with dry cold air) I haven't notice any revolutionary results in terms of younger skin more than from the tretinoin I use. I will say though, the capacity to keep moisture in skin and keep dryness at bay, then the Egf is outstanding. I can have the most dry flaky skin, and if I put it on at night, I wake up with soft, moisturized skin that arent dry anymore. And it only requires a tiny drop from the serum, it's potent in that way.

  • @KingKikikoi
    @KingKikikoi 4 месяца назад +2

    So sorry I doubted you Angie! Going into this video I wasn’t sure if you were going to do the right thing. But you sure came fully prepared and I am so impressed with the time you took on the research and the variations of papers you sited plus your own experiences! You are the goat!

  • @jennicrow2946
    @jennicrow2946 4 месяца назад +14

    So comprehensive! Was hoping you would do a video on this. I agree, the bottom line is if it could potentially make a skin cancer cell grow then it may not be worth it.

    • @Tsili-Walela
      @Tsili-Walela 4 месяца назад

      I saw a Huberman Lab podcast on skin and when the dermatologist said that, I knew I was out. I already had a stage 0 melanoma. Not taking that chance.

  • @stephanieflechter6978
    @stephanieflechter6978 4 месяца назад

    I respect your research and information that is provided in your videos. I know anytime I watch I can trust the information provided. I’m 52 and have followed your skincare regime for 5 plus years and I’m often told I look like I’m 40!! Thank you for your hard work!!

  • @marcyjackson7577
    @marcyjackson7577 4 месяца назад +8

    I am trying Calecim PTT-6 professional serum, almost done with vile #2 and just ordered #3. I am noticing the elasticity and overall plumpness of my skin especially my neck skin is better (not like in my 30’s or anything but it is improved) and my overall skin texture is improving, which was what I was hoping for. I blend three drops of the serum with Vichy Mineral 89 for better slip AM & PM. I have large pores due to sun damage and am post menopausal 56yr old using transdermal HRT. I have been using retin-a for 6yrs thanks to you, and vitamin-c serum as well. This brand is also approved for use with micro needling (I did a series of 4 treatments 3yrs ago and it works well for me with collagen stimulation and pores) so just had one of four in office MN treatment and used this after and my healing time was faster and I was not as red or puffy the next day. I plan to give this a good six months and decide from there, but as of right now I’m liking this addition to my skin care routine and it doesn’t interfere with the other goodies I’m using. Love your channel, Angie! Xxx

    • @AnD-bu4xs
      @AnD-bu4xs 4 месяца назад +2

      yes, I also have very nice results with calecim serum.. I am on my second bottle and will give a try with third also

    • @d.a.5982
      @d.a.5982 4 месяца назад +1

      One more vote for Calecim!

  • @wendywittmann
    @wendywittmann 4 месяца назад +1

    I'm grinning from ear to ear. You totally KILLED IT, Angie! As someone who has spent way too much money on these products, I'm so happy to see the research. You've found your calling!

  • @manonsinclairladyofblairad9675
    @manonsinclairladyofblairad9675 4 месяца назад +7

    Hi Angie, once again you did a comprehensive research to save us some big money. Thank you!!!

  • @karimenlee
    @karimenlee 4 месяца назад +2

    absolutely love your looking at the science behind. you do hard work for us. thank you so much. I had followed you since pretty much the beginning of you on youtube. other's come and go, but I always have you in my corner.

  • @deniseavt
    @deniseavt 2 месяца назад +31

    Yay now your videos are showing up after watching the retirement one. Do NOT retire please 🙏🏻

  • @patkern185
    @patkern185 4 месяца назад

    Great video, Angie! I'm here for all the nerdy, science-y stuff that you do so well! Thanks for providing information that debunks outrageous claims and noting that growth factors can't discern healthy cells from diseased cells... something that has stopped me from ever using them. At 75, I don't expect miracles from skincare products, just healthy improvement and a slowing down of the signs of aging. You always do a thorough dive into facts and science, and it shows in how young and healthy you look. I'm so happy I found your channel so many years ago. I'm a disciple. Have a fantastic weekend, gorgeous! XXOO ❤️ ❤️

  • @janicelphillips
    @janicelphillips 4 месяца назад +9

    Hey there! I’m over here flying my ‘nerd flag’! Thanks for the deep, deep dive into the research of these claims! I’ve been following you since just after you started your journey and have taken it ALL in to develop my skin care routine. At 72 years old now, it’s never too late to be our best selves! Thank you and thank you again for your efforts on our behalf. ❤️😘

  • @Stvlw7bxnow
    @Stvlw7bxnow День назад

    This is exactly what I was looking for. I'm having microneedling done and I was offered Omni Core Recovery Complex, which is a growth factor serum. It claims to speed recovery time, reduce inflammation, minimize irritation, and reduce redness and heat. Thanks to your video, I will be declining this serum and saving a lot of money ☺️

  • @reneklein6049
    @reneklein6049 4 месяца назад +17

    Hi Angie. You are a scientific genius. I love all of your research and how well you delve into these studies.
    I think I personally will skip the growth factors, and continue my experimentation with the vaginal estradiol used topically on my face in combination with the Tretinoin. So far, it's only been 3 weeks of using estradiol twice a week. I most likely need to bump it up.
    By the way, for anyone interested, if you use a Good RX coupon for Tretinoin, for some reason the brand name, Retin-A is cheaper! It's also much creamier and therefore you need less than the generic.
    Timeless Skincare is definitely the way to go for other products. I use all that you have recommended. I would never be without the Vitamin C, nor their Coq-10 serum.
    You are the best!
    Have a great weekend. Stay dry. We're finally getting much needed rain!❤🌧🌧🌂🌫

    • @kimberlyf4888
      @kimberlyf4888 4 месяца назад +1

      Same here, but I apply the estradiol cream about 5x/week, Tretinoin a couple days a week, and OneSkin daily.

    • @KarenGaylor4712
      @KarenGaylor4712 4 месяца назад

      I would love to know how your vaginal estradiol on the face works out. It's an interesting concept. I know several menopausal women using it vaginally, but no one using it on the face.

    • @reneklein6049
      @reneklein6049 4 месяца назад

      ​@kimberlyf4888 I'm going to up the estradiol dosage, but so far it's been fine in combination with the Tretinoin. A bit drying, but I always seal everything in with a moisturizer. 😊

    • @KarenGaylor4712
      @KarenGaylor4712 4 месяца назад

      @@kimberlyf4888 do you find the OneSkin to be worth it? I'm looking at the eye cream because that's where most of my wrinkles and fine lines are. I basically have a smooth face and very very fine lines. Biggest issue for my face and neck is sagging from 100+ lbs loss 3 yrs ago and surgery is the only way to fix that.

    • @marianne-8979
      @marianne-8979 4 месяца назад

      Be careful that you’re not taking too much estrogen if you use it both on your face and vag. Estradiol is much stronger than estriol

  • @strawberry1025
    @strawberry1025 4 месяца назад +1

    As always l bow to thee O Skin Oracle.🎉 Not only for your wonderful deep dive research but also your flawless presentation and communication of all you've found. No one has more clarity. Thank you! 😊

  • @latherandlace
    @latherandlace 4 месяца назад +7

    I can't use growth factors because I had skin cancer. 😢 But, thank you for such a great presentation of growth factors! I've never heard anyone explain it so well. Have a great weekend ❤~lori

  • @ifwallace1
    @ifwallace1 4 месяца назад

    I love the content on this channel. She always does a deep dive, is knowledgeable and gives me confidence in the authority of what she says. The content is presented in an amazing way. A true teacher here. Thank you for your thorough approach that cuts thru the fluff. Keep it up.

  • @axisgirlvaughn7446
    @axisgirlvaughn7446 4 месяца назад +227

    As others have requested, I am eagerly awaiting your in depth review of estrogen cream for your face (estriol or estradiol?).

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад +148

      That video will come out in December.

    • @jeanlrollins5901
      @jeanlrollins5901 4 месяца назад +19

      I hope you will address whether HRT might affect the efficacy of topical hormonal therapy…. Thanks for all you do Angie! Love your content.

    • @axisgirlvaughn7446
      @axisgirlvaughn7446 4 месяца назад +8

      Thank you. I am sure I am not alone in looking forward to this

    • @KingKikikoi
      @KingKikikoi 4 месяца назад +7

      @@AngieHotandFlashyhave you checked out dr Abs video of testosterone cream? For women too. He’s brought out compelling research and doing it himself, also he said oestrogen isn’t that great for anti aging compared to testosterone.

    • @user-xc7iq4cm8t
      @user-xc7iq4cm8t 4 месяца назад +10

      Yes !! I’m wondering if HRT is worth it at 61.

  • @patriciastark7292
    @patriciastark7292 4 месяца назад

    Thank you for an excellent unbiased review of human growth factors. My anti-aging MD takes expensive human growth hormone injections, and the skin on her face and body look absolutely beautiful. I personally would not use human or plant based growth factors because I had breast cancer several years ago, and I don’t want to activate any cancer stem cells that may remain in my body. Excellent video Angie! Thank you for the research deep dive! I certainly appreciate your research! I always learn so much from your posts! 💜

  • @StayFabulouswithNisha
    @StayFabulouswithNisha 4 месяца назад +20

    Hi sis, great video. I have been looking into EGF for a while and have been using EGF serum(from human stem cells) for over a month now and I can't see any significant difference, maybe if you looked under a microscope lol. I have heard that using it with microneedling might be more effective. I am giving up on finding a miracle cure we are all going to get old and wrinkly eventually 🤣🤣Love ya xoxo Nisha

    • @dvanhottie
      @dvanhottie 3 месяца назад

      I’ve been to scared to try after reading somewhere it could accelerate skin cancer.

  • @creditreporthelp
    @creditreporthelp 3 месяца назад

    Excellent. Long-time fan, Angie. Thanks for your candor and honesty.

  • @lisas7516
    @lisas7516 4 месяца назад +4

    i can't believe you just posted this video... i just asked myself this morning, "I wonder what Angie thinks of growth factors?". TY

  • @Sweetnessjuju13
    @Sweetnessjuju13 4 месяца назад +2

    Thanks again for doing the hard work! Had several bad sunburns as a child, so not worth the risk to awaken any cancer cells, will keep using Trentinoin and sunscreen ❤❤❤

  • @kellyfleming251
    @kellyfleming251 3 месяца назад +5

    Hi Angie! Might you have the time to look into the OS-1 peptide, and OneSkin products?

  • @debbiepayne903
    @debbiepayne903 2 месяца назад

    Thanks for your research. Always helpful! I fell for a SkinMedica and a Neocutis product once. They did nothing! I can spend the $200 dollars towards a nice vacation. You’re the best!

  • @smitasingh6462
    @smitasingh6462 4 месяца назад +5

    Love that blue color on you Angie.

  • @kittybeanz102
    @kittybeanz102 Месяц назад +1

    Wowza! I love love love your in depth reviews like this. I believe in science so I nerded out on this one. You are just amazeballs and thank you so much for all the vast amount of time you must spend on your research. I am 69 and tend to grant most new supposedly miracle potions to keep my skin looking as good as possible. You just saved me a boatload of money because I won’t fall for these growth factor products. Did I say that I loved this video?

  • @lauriemcclelland9845
    @lauriemcclelland9845 4 месяца назад +7

    Good morning Angie! Thank you for all the thorough research you do for us. I have been following you and have been using your skin regimen as closely as a I can for a few years. I get so many complements on my skin. I am in my early 60s. 😊Could you please review at some point the products from OneSkin and Adipeau ?

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад +4

      Hi Laurie! That's awesome to hear! I'll put them on the list! 💜

    • @bhall9874
      @bhall9874 4 месяца назад +3

      I've actually been using Adipeau for the last two years and a bit. While it may also do some nice things for the skin, it's primarily a fat cream. That is, it's designed to help with loss of facial fat. I don't think Angie has any significant fat loss at this point, so I don't think Adipeau would do anything for her.
      Based only on my own experience, I think it does work to some extent. It didn't give me filler-type results, but it did restore some fat to the right hand side of my face. Benefits to the left hand side are less noticeable but extant. It's probably worth noting that my left side lost facial fat first. Adipeau also helps with the small hollows on the inside tops of my eyebrows. Alas, it did not help noticeably with my undereye hollows, but I've been happy enough with what it's done that I keep up a maintenance level. Also, it can take time that differs from person to person. For example, a You Tube journalist had some results with it within three months and not much more after that. It took six months for me to see anything (except lip plumping), but in the 7th month I got fast results for a bitand then incremental improvement for about another year. I'm now 72, by the way.

  • @Gather2Grow
    @Gather2Grow 3 месяца назад

    Thank you, Angie! Long time listener and very grateful for all the research you do.🥰

  • @laurieD1970
    @laurieD1970 4 месяца назад +31

    So basically growth factors don’t work and they are mainly just humectants? WOW so good to know. I’m going to start saving some $$ ❤

    • @christinemangan7642
      @christinemangan7642 3 месяца назад

      Right? I have one on subscription and am canceling now!

  • @susanjacobs9784
    @susanjacobs9784 4 месяца назад

    Thank you, Angie! Your sharing of research and data from clinical studies is so helpful and appreciated! And just explaining what the heck growth factors are! I love you how you keep reminding your viewers of what actually has been proven to work and inform about what would be a huge waste of $$. Thank you again!!

  • @jdnicholas8194
    @jdnicholas8194 4 месяца назад +7

    Really informative and useful (and your hair looks great today!)

  • @Karen-DeMars
    @Karen-DeMars 4 месяца назад

    What an excellent, detailed, comprehensive yet completely understandable review and analysis of the data … well done! Thanks so much, Angie.👏🤓👍

  • @christinatruchon1924
    @christinatruchon1924 4 месяца назад +5

    Thank you for your research and honesty.

  • @carriepetersen2377
    @carriepetersen2377 4 месяца назад +2

    I’m 62 and noticed a big difference when using Necutics BioFirm on my neck so I will be sticking with it. Thank you for the review though.

  • @patticarnevale2360
    @patticarnevale2360 4 месяца назад +4

    Thank you for taking the time to research this.

  • @theresaharder918
    @theresaharder918 2 месяца назад

    Your video popped up right away on my feed! Progress!!❤

  • @lynnecarr5791
    @lynnecarr5791 4 месяца назад +28

    Thanks Angie! I have avoided growth factors. I am hearing a lot about DNA repair enzymes. Would you consider doing a video on this?

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад +19

      Absolutely!

    • @JonEllis-o1q
      @JonEllis-o1q 4 месяца назад +1

      I’m on my first bottle and also would love more info!

    • @LisaNix2
      @LisaNix2 4 месяца назад

      @@lynnecarr5791 I’m using DNA repair in my sunscreen (Isdin) and I’m loving it!

    • @tamikops
      @tamikops 4 месяца назад +7

      I just started the DNA repair enzymes as well. Wondering if it’s worth my money and time

    • @user-xc7iq4cm8t
      @user-xc7iq4cm8t 4 месяца назад

      Everything changing so rapidly with technology. I planned on a f/l around this time but hoping I don’t have to. I haven’t tried OmniLux mask/red light therapy yet. Hv been told tox will no longer mk my 11’s disappear bcuz they’re static. Might just try the Omnilux b4 I plan on surgery!!

  • @jgoldfarb3
    @jgoldfarb3 2 месяца назад

    Angie, you do so much investigating into everything you recommend to us, I believe you100% and always try if it’s something I’ve been wanting to truly!🌹🙌

  • @tcm3097
    @tcm3097 4 месяца назад +34

    Oh my goodness. While science advancements are very much appreciated, let’s face it, nothing will turn back the clock. Being and accepting your best self in every stage of life is the healthiest approach. The cosmetic industry is well aware of the “taboo” of aging in our society, especially for women, and they seek to financially capitalize on it. None of us are getting out of this life, “alive”. We are all going to age. Just do the tried and proven: limit sun exposure, wear sunscreen, use a retinoid or tretinoin, moisturize face and body, eat healthily, do both cardio and strength training min of 5 days per week. You are all set.

    • @anniesimone
      @anniesimone 4 месяца назад +1

      Amen to that!

    • @courtneyjackson4843
      @courtneyjackson4843 4 месяца назад +2

      I got convinced I needed Growth factors, so I purchased the Neocutis one...and nothing absolutely nothing changed.

    • @christinemangan7642
      @christinemangan7642 3 месяца назад +1

      This!

  • @acetheshe8700
    @acetheshe8700 2 месяца назад

    Thank you Angie for this extensive research. You're awesome❤

  • @robinaltman8151
    @robinaltman8151 4 месяца назад +4

    Hi Angie! I'm a 61 year old doctor who's super interested in skincare and I've been following you for years. I use all the products you recommend (including the lasers) and get compliments on my skin all the time. This was the best video - so well explained and intelligent. You are wonderful and thanks for all you do! 😍

  • @res1718
    @res1718 2 месяца назад +1

    Excellent research, digested and then delivered for nerds and non nerds!

  • @abcdef156393
    @abcdef156393 4 месяца назад +5

    LOVE the deep dives!!!!

  • @lorianthony4892
    @lorianthony4892 2 месяца назад

    Hi Angie! I enjoy your videos. I have been following for 10 years

  • @NowIknow-c3c
    @NowIknow-c3c 4 месяца назад +96

    I used Neogenesis Recovery for over a year and saw no changes at all.

    • @platinum11110
      @platinum11110 4 месяца назад +11

      Thank you, it's so difficult to find opinions!

    • @Alykat736
      @Alykat736 4 месяца назад +7

      I was recommended that product over the skin medica TNS . Thank you for sharing your experience.
      I’m sticking with the TNS for now . I’ve seen ppl who use it religiously and there skin looks younger than there age . Bc of its cost (with even its crummy pump dispenser) I just don’t spend money on other products, it covers all my skins needs -except for sunblock and retin a which I still Purchase , but both those are very affordable lol

    • @user-xc7iq4cm8t
      @user-xc7iq4cm8t 4 месяца назад

      @@Alykat736 - so you use Retin A and the other product?

    • @maureenturk8578
      @maureenturk8578 4 месяца назад +5

      Same thing for me with TNS. My dermatologist recommended it - I used it - didn’t see a difference.

    • @rambotheragdoll8940
      @rambotheragdoll8940 4 месяца назад +7

      I stopped using growth factors after using it for 5 years. The skin cancer experts are concerned that the skin growth factor’s will grow both the healthy and the cancerous cells.

  • @crisnemitz1606
    @crisnemitz1606 4 месяца назад

    Angie, you are such a wonderful source for all of us people who didn't love science classes growing up. Thank you so much for all the work you put in to your videos.
    I wish this video came out last week. I just ordered 2 serums from Allies of Skin. Now I'm worried about negative effects. 🤦‍♀️

  • @margot9647
    @margot9647 4 месяца назад +3

    I hadn't seen your 2017 trial of TMS, and before your video started my first thought was that I did try a full bottle and saw zero results. Glad I'm not alone. Instead of buying it, I can save that money and get another Halo laser where I actually did get amazing results. And of course Tret and sunscreen

    • @margot9647
      @margot9647 4 месяца назад

      TNS

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад +2

      A laser treatment is definitely a better use of that money than a bottle of TNS (IMHO) 💜

  • @deborahgrogan1919
    @deborahgrogan1919 4 месяца назад

    Thanks for another fact based and well presented video on skincare! I always enjoy these - they are unbiased, scientific enough, and use terms this older gal can comprehend. Much appreciated!!

  • @margot9647
    @margot9647 4 месяца назад +52

    When are you covering the estrogen cream. I got my compounded Estriol cream about 9 days ago. Also putting on my hands and forearms. They are in rough sun damaged shape after 59 years.

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад +62

      I'm doing a 6-month trial on it (that's how long they say it takes to see a difference) so I'll do a video on it in early December.

    • @margot9647
      @margot9647 4 месяца назад +11

      @@AngieHotandFlashy perfect! I'm having a delayed midlife crisis getting so close to 60. I've got my large menopause tool kit, walking daily, trying to get enough protein, weighted vest+++🤣

    • @thedesigndaily
      @thedesigndaily 4 месяца назад +1

      Love the deep dives! Had same ? re the estrogen cream (using Alloy) and now wonder is it “small enough” to penetrate skin? Since it’s a hormone, don’t know if that works differently? Thank you!

    • @elsagrace3893
      @elsagrace3893 4 месяца назад

      Estriol is too weak to do anything. Estriol is the estrogen that is left after menopause because it is produced in body fat. What waste your time and money?

    • @margot9647
      @margot9647 4 месяца назад

      @elsagrace3893 fat cells make estrone. Estriol is made when you're pregnant . They actually have pub med articles comparing Estradiol and Estriol on skin and aging with similar results improving collagen and elastin. It's froma compoundingpharmacynot Amazon. Pharmaceuticalgrade.

  • @wendybitker7498
    @wendybitker7498 4 месяца назад

    Thank you for this deep dive, Angie! I'm sticking with the skincare routine and products I have now. Btw, the colour of your top makes your eyes look so beautiful! Once again, thanks for all you do!

  • @amandamcadam114
    @amandamcadam114 4 месяца назад +4

    Im a scientist with study design and statistics training. An absolute bare minimum should be 30 patients treated with product and with another 30 controls, and with patients at those low numbers, should have the same age, gender and skin types and skin damage. Measures should be be objective and not "patient felt skin was younger looking" means nada. Drives me crazy...

  • @vickyhandal4651
    @vickyhandal4651 4 месяца назад

    Love the nerdy videos! Bravo Angie! Always so informative, have a wonderful and blessed week!

  • @easyfrenchdiet
    @easyfrenchdiet 4 месяца назад +11

    Hello Angie, great video, your blue top suits you very well. May I suggest a deep dive into sculptra, radiesse, etc. if you have the time. Have a nice day.

  • @juliabinford6500
    @juliabinford6500 4 месяца назад

    You did a really nice job of translating that research. You organized this so well to build up to a conclusion. Bravo!!

  • @sameold1212
    @sameold1212 4 месяца назад +5

    Thank you for saving us a lot of money! 😊

  • @corinnecourchaine4416
    @corinnecourchaine4416 4 месяца назад +2

    This was the perfect video to pair with my morning coffee. Your sciencey talks help me forget about my problems, much appreciated!

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад

      So happy it helped! & hope you have a better day! 💜

  • @sarahledbetter7118
    @sarahledbetter7118 4 месяца назад +4

    Thank you for all your research!

  • @SteffanieLiebman
    @SteffanieLiebman 4 месяца назад

    Thank you so much! That was very helpful to hear the whole story & not just the bits & pieces that float around! I love that you always do your research & that is one of the many reasons I have been watching you for years! Thank you for all the thousands of hours of time, research & effort you go to help keep us informed! Love watching all of your videos! 🙂

  • @vickierotell4995
    @vickierotell4995 4 месяца назад +3

    Thanksnfor confirming what I thought tried Skin Medica back in 2013, and didn't see any amazing results. The COST IS OUTRAGEOUS. Have you deep dived Cosrx? Just turned 60 with very dry skin. Looking for fine lines and deep wrinkle help. Finally broke down and got the Snail 96 Mucin and eye cream. Was impressed with the hydration. Then I saw a utube video on Cosrx The 6 Peptide Skin Booster so I purchased the peptide along with their Spa Mask and All in one cream. 1st use of the peptide serum I saw immediate plumping of my deep forehead wrinkles. I've only been using less then a week but I'm impressed. Plays well with my Ordinary Retinol. Help with large pores that I've developed post menopause. All products purchased on Amazon at reasonable prices. Would love to know your thoughts. Thanks for your deep dives and time. ❤❤❤

  • @shannonbellamy5186
    @shannonbellamy5186 4 месяца назад +1

    Love this content! And Thankyou for diving deep!!😊 I’m a nerdy RN and I really appreciate this type of information! Would love your next deep dive to inform us on DNA repair enzymes!❤

  • @kelleycranny3972
    @kelleycranny3972 4 месяца назад +27

    Please do a deep dive into the ingredient "volufiline". Curious🤔

    • @nn7397
      @nn7397 4 месяца назад +6

      Yeah me too!!

    • @moongoddess5858
      @moongoddess5858 4 месяца назад +2

      I use Dr. Rajani’s cream and see no difference. Big disappointment because it’s really expensive!

    • @kelleycranny3972
      @kelleycranny3972 4 месяца назад

      @@moongoddess5858 yeah, I watch him and have followed his advice on some things but his products are way out of my price range! Have a feeling that volufiline is really hyped up.

    • @anniekj6421
      @anniekj6421 4 месяца назад

      @@moongoddess5858hi I follow him too which cream do you use? I was thinking of ordering from him TIA

  • @smallnwise1
    @smallnwise1 4 месяца назад +1

    thanks Angie! Glad to see the 500 dalton rule & (all) peptides addressed. I remember learning at some point that one particular company solved this (Alastin) but, unless and until I see the people I trust address this, I won't spring for it. Really appreciate you taking a deep dive.

  • @mabimorgan4316
    @mabimorgan4316 4 месяца назад +6

    Hi Angie! Love your channel! Please try TIZO Primer/Sunscreen mineral tinted SPF 40 please. I know you tried another TIZO mineral sunscreen but the one I reference is AMAZING!!

    • @AngieHotandFlashy
      @AngieHotandFlashy  4 месяца назад

      I'm pretty sure I tried that one 7-8 years ago & it wasn't my cup of tea, but I'm so happy you love it! 💜

    • @renuk3493
      @renuk3493 4 месяца назад

      Love it too!

  • @kelleyjohnson2637
    @kelleyjohnson2637 4 месяца назад

    Wow, Angie...thank you SO much for doing an honest deep dive into this subject. I feel like we are bombarded by so many marketers and influencers about growth factors. You are the BEST!!!