Fecal Transplants: Paving the Future for Crohn’s Disease

This video looks at role of the bacteria and other microbes living within the human gut, referred to as the gut microbiome. It also explores how understanding more about them could hold the key to developing new treatment options for individuals with Gastrointestinal diseases such as Crohn’s Disease. These individuals often have an altered composition of their gut bacteria. In this video, we talk about a new therapy called Fecal Microbiome Transplants that aims to restore the composition to resemble a healthy microbiome.
This series was created by collaborative efforts of the McMaster students Sara Araz, Jaskaran Benepal, Alyssa Ciampa, and Aarchie Soni within the McMaster Demystifying Medicine Program.
We would like to thank Dr. Nikhil Pai for his valuable contributions to this video and his expert inputs.
Please note these videos are not meant to act as medical information or instruction and are solely for educational purposes. Please consult your health care provider for information about your health.
Copyright McMaster 2023.
#Gutmicrobiome #Crohns #scienceeducation #Fecalmicrobiometransplant #DemystifyingMedicine
References
Bojanova, D. P., & Bordenstein, S. R. (2016). Fecal Transplants: What Is Being Transferred? PLOS Biology, 14(7), e1002503. doi.org/10.1371/journal.pbio....
Boston, 677 Huntington Avenue. (2017, August 16). The Microbiome. The Nutrition Source. www.hsph.harvard.edu/nutritio...
Gupta, S., Allen-Vercoe, E., & Petrof, E. O. (2016). Fecal microbiota transplantation: in perspective. Therapeutic Advances in Gastroenterology, 9(2), 229-239. doi.org/10.1177/1756283X15607414
Kaakoush, N. O. (2020). Fecal transplants as a microbiome-based therapeutic. Current Opinion in Microbiology, 56, 16-23. doi.org/10.1016/j.mib.2020.05...
Mayo Clinic Staff. (2022, August 6). Crohn’s disease - Symptoms and causes. Mayo Clinic. www.mayoclinic.org/diseases-c...
Rinninella, E., Raoul, P., Cintoni, M., Franceschi, F., Miggiano, G. A. D., Gasbarrini, A., & Mele, M. C. (2019). What is the Healthy Gut Microbiota
Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases. Microorganisms, 7(1), 14. doi.org/10.3390/microorganism...
Robertson, R. (2017, June 27). Why the Gut Microbiome Is Crucial for Your Health. Healthline. www.healthline.com/nutrition/...
Zhang, Y.-J., Li, S., Gan, R.-Y., Zhou, T., Xu, D.-P., & Li, H.-B. (2015). Impacts of Gut Bacteria on Human Health and Diseases. International Journal of Molecular Sciences, 16(4), 7493-7519. doi.org/10.3390/ijms16047493

[@philliprichards1660]

My wife has severe Crohn's which has brought her many years of suffering including many surgical procedures which included a few brushes with death. I am extremely grateful to the medical community for helping her fight through it time and again. I pray that one day the medical community can create a method to reverse this illness.

[@bradleywebster3086]

Very good 👍🏿

[@susannoel6396]

I would also recommend researching the affects of toxic metals in the body and exposure to high levels of EMFs, (Electromagnetic Frequencies) I suspect doing a toxic metal cleanse as well as the therapy you are speaking of, the combination of both, can really do wonders for many with intestinal problems. Eating a wide cariety of fresh fruits and vegetables will also help to fight against the harmful affects of EMFs.

[@joeypchajek]

Generally not a good idea to do cleanses or detoxes until one first makes sure they are nourished and healthy enough to handle it and even properly get through it.
Most do it backwards, straight to detox before getting nourished.
Often they then get sicker and sicker.