i dont mean to be off topic but does someone know a tool to log back into an Instagram account..? I stupidly forgot my password. I would love any help you can offer me
@Kyrie Dustin Thanks so much for your reply. I found the site on google and Im trying it out atm. Looks like it's gonna take quite some time so I will reply here later when my account password hopefully is recovered.
soo helpful i just want to ask a stupid question each tyrosine phosphorylate the other one that is in front of it right? why do we use 6ATP molecules, why not just 3?
So, RTKs are encoded by many genes in our DNA. That means we have different subfamilies (they contain different numbers of tyrosine residues in the cytosolic part -> in the video I drew just 6 but it can be even more). So depending on the subfamily of the RTK much more Phosphates can bind to the cytosolic part. To your question now: In theory 2 would be enough, right. But over the evolution, it one can speculate that it was advantageous for the genes to carry more tyrosine domains (it might be that cells and by that even animals with more domains had a selective advantage over cells with fewer phosphate binding RTKs (but since it is evolution, this is just speculation)
I think you can also add that cell reception typically amplifies the response, this is advantageous for stuff like hormones, at the end of the day if your pituitary gland releases lets say 1000 molecules of ADH (again the number is small for simplicity sake, your gland would release millions of these) there is no way to know how many of them would actually bind to the nephrons in your kidney, however we still need to produce an adequately large response therefore the ability of a single ligand to cause a lot of intracellular change is desired, this increases the efficiency as less ligand needs to be manufactured. Does that make sense?
![I.N "HALLUCINATION" | [Stray Kids : SKZ-PLAYER]](http://i.ytimg.com/vi/n5B5q1Hwt_U/mqdefault.jpg)
This was beyond helpful. 10/10 quality information
Woooow, !!!!! thank you for so much effort in putting this great videos together. 👏🏿👏🏿👏🏿👏🏿👏🏿
Great video - thank you so much for creating and sharing :)
Thank you so much 😊 ✨
Thanks for the video, was really quite helpful.
thank you so much! incredibly good!
Thank you so much!
Thank you so much ❤
thank you this was well explained
Thank you !!!! I don't speak English but I understand this video well. The illustrations are really well done.
bro what r u doing rn 🙂
brilliant explanation -- thank you!
thaaanks
Very easy to understand, thank you!
great video
Thaaaaaanks ❤❤❤❤❤❤❤
Thanks alot , this was very helpful !
❤❤❤ thanks
Wonderfully explained!
i dont mean to be off topic but does someone know a tool to log back into an Instagram account..?
I stupidly forgot my password. I would love any help you can offer me
@Jesse Steven instablaster =)
@Kyrie Dustin Thanks so much for your reply. I found the site on google and Im trying it out atm.
Looks like it's gonna take quite some time so I will reply here later when my account password hopefully is recovered.
@Kyrie Dustin it worked and I now got access to my account again. Im so happy:D
Thanks so much you really help me out :D
@Jesse Steven Happy to help :)
Plz make a video about ras raf pathway
absolut hammer! you should make a video on nonreceptor t kinases now to complement this one, or are they so similar it wouldn't make sense to?
it was really helpful, thank you
soo helpful
i just want to ask a stupid question
each tyrosine phosphorylate the other one that is in front of it right?
why do we use 6ATP molecules, why not just 3?
So, RTKs are encoded by many genes in our DNA. That means we have different subfamilies (they contain different numbers of tyrosine residues in the cytosolic part -> in the video I drew just 6 but it can be even more). So depending on the subfamily of the RTK much more Phosphates can bind to the cytosolic part.
To your question now: In theory 2 would be enough, right. But over the evolution, it one can speculate that it was advantageous for the genes to carry more tyrosine domains (it might be that cells and by that even animals with more domains had a selective advantage over cells with fewer phosphate binding RTKs (but since it is evolution, this is just speculation)
I think you can also add that cell reception typically amplifies the response, this is advantageous for stuff like hormones, at the end of the day if your pituitary gland releases lets say 1000 molecules of ADH (again the number is small for simplicity sake, your gland would release millions of these) there is no way to know how many of them would actually bind to the nephrons in your kidney, however we still need to produce an adequately large response therefore the ability of a single ligand to cause a lot of intracellular change is desired, this increases the efficiency as less ligand needs to be manufactured. Does that make sense?
wow super helpful!! thank you so much
Thank you
Thanks
It was, thanks a lot
What is GRB2
Why did you say trinucleotide?
Sooo helpful
Big thank to Allah then then to you
💕🙏🏻💕🙏🏻🙏
Thank you